Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells

European Journal of Pharmacology

Volumn 587, Issue 1-3, 2008, Pages 25-34

  Gosslau, Alexander ^a,b   Pabbaraja, Srihari ^a,b   Knapp, Spencer ^a,b   Chen, Kuang Yu ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b The Cancer Institute New Jersey   (United States)

Author keywords

Apoptosis; Mitochondria; p53; Resveratrol; Trans and cis stilbenes

Indexed keywords

CYTOCHROME C; DNA; MITOCHONDRIAL PROTEIN; POLYPHENOL; PROTEIN P21; PROTEIN P53; STILBENE; STILBENE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL DISRUPTION; CELL GROWTH; CIS ISOMER; COLORECTAL CARCINOMA; DEPOLYMERIZATION; DNA FRAGMENTATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MICROTUBULE; MITOCHONDRION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN SECRETION; STRUCTURE ACTIVITY RELATION;

APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; DNA FRAGMENTATION; ENZYME ACTIVATION; FLAVONOIDS; FLUORESCENT DYES; HUMANS; MEMBRANE POTENTIALS; MICROTUBULES; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; PHENOLS; RHODAMINE 123; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 44149087812     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.03.027     Document Type: Article

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