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Volumn 19, Issue 4, 2005, Pages 925-938

Feedback inhibition of leptin receptor/Jak2 signaling via Tyr 1138 of the leptin receptor and suppressor of cytokine signaling 3

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ERYTHROPOIETIN RECEPTOR; JANUS KINASE 2; LEPTIN RECEPTOR; RNA;

EID: 15444366416     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2004-0353     Document Type: Article
Times cited : (120)

References (45)
  • 5
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL 1998 Leptin and the regulation of body weight in mammals. Nature 395:763-770
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 8
    • 0033578334 scopus 로고    scopus 로고
    • Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction
    • Li C, Friedman JM 1999 Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. Proc Natl Acad Sci USA 96:9677-9682
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9677-9682
    • Li, C.1    Friedman, J.M.2
  • 9
    • 0034640508 scopus 로고    scopus 로고
    • Activation of downstream signals by the long form of the leptin receptor
    • Banks AS, Davis SM, Bates SH, Myers Jr MG 2000 Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 275:14563-14572
    • (2000) J Biol Chem , vol.275 , pp. 14563-14572
    • Banks, A.S.1    Davis, S.M.2    Bates, S.H.3    Myers Jr., M.G.4
  • 13
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek C, Uotani S, da Silva B, Flier JS 1997 Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 272:32686-32695
    • (1997) J Biol Chem , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    Da Silva, B.3    Flier, J.S.4
  • 16
    • 0034548763 scopus 로고    scopus 로고
    • Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
    • Eyckerman S, Broekaert D, Verhee A, Vandekerckhove J, Tavernier J 2000 Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor. FEBS Lett 486:33-37
    • (2000) FEBS Lett , vol.486 , pp. 33-37
    • Eyckerman, S.1    Broekaert, D.2    Verhee, A.3    Vandekerckhove, J.4    Tavernier, J.5
  • 17
    • 0034724677 scopus 로고    scopus 로고
    • SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
    • Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F 2000 SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J Biol Chem 275:12848-12856
    • (2000) J Biol Chem , vol.275 , pp. 12848-12856
    • Schmitz, J.1    Weissenbach, M.2    Haan, S.3    Heinrich, P.C.4    Schaper, F.5
  • 18
    • 0038676954 scopus 로고    scopus 로고
    • Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2
    • Fairlie WD, De Souza D, Nicola NA, Baca M 2003 Negative regulation of gp130 signalling mediated through tyrosine-757 is not dependent on the recruitment of SHP2. Biochem J 372:495-502
    • (2003) Biochem J , vol.372 , pp. 495-502
    • Fairlie, W.D.1    De Souza, D.2    Nicola, N.A.3    Baca, M.4
  • 19
    • 0032788884 scopus 로고    scopus 로고
    • Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells
    • Kim H, Baumann H 1999 Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells. Mol Cell Biol 19:5326-5338
    • (1999) Mol Cell Biol , vol.19 , pp. 5326-5338
    • Kim, H.1    Baumann, H.2
  • 20
    • 0036681955 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
    • Hortner M, Nielsch U, Mayr LM, Johnston JA, Heinrich PC, Haan S 2002 Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J Immunol 169:1219-1227
    • (2002) J Immunol , vol.169 , pp. 1219-1227
    • Hortner, M.1    Nielsch, U.2    Mayr, L.M.3    Johnston, J.A.4    Heinrich, P.C.5    Haan, S.6
  • 24
    • 0034004130 scopus 로고    scopus 로고
    • Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bβ
    • Rui L, Gunter DR, Herrington J, Carter-Su C 2000 Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bβ. Mol Cell Biol 20:3168-3177
    • (2000) Mol Cell Biol , vol.20 , pp. 3168-3177
    • Rui, L.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 25
    • 0033544899 scopus 로고    scopus 로고
    • SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms
    • Ram PA, Waxman DJ 1999 SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. J Biol Chem 274:35553-35561
    • (1999) J Biol Chem , vol.274 , pp. 35553-35561
    • Ram, P.A.1    Waxman, D.J.2
  • 26
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: Proceed a your own RSK
    • Blenis J 1993 Signal transduction via the MAP kinases: proceed a your own RSK. Proc Natl Acad Sci USA 9089: 5889-5892
    • (1993) Proc Natl Acad Sci USA , vol.9089 , pp. 5889-5892
    • Blenis, J.1
  • 27
    • 0038292961 scopus 로고    scopus 로고
    • SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling
    • Ridderstrale M, Amstrup J, Hilton DJ, Billestrup N, Tornqvist H 2003 SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling. Horm Metab Res 35:169-177
    • (2003) Horm Metab Res , vol.35 , pp. 169-177
    • Ridderstrale, M.1    Amstrup, J.2    Hilton, D.J.3    Billestrup, N.4    Tornqvist, H.5
  • 31
    • 0028179013 scopus 로고
    • Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor β to Ras
    • Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG 1994 Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor β to Ras. Proc Natl Acad Sci USA 91:7335-7339
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7335-7339
    • Bennett, A.M.1    Tang, T.L.2    Sugimoto, S.3    Walsh, C.T.4    Neel, B.G.5
  • 32
    • 0033569730 scopus 로고    scopus 로고
    • The role of SOCS-3 in leptin signaling and leptin resistance
    • Bjorbaek C, El Haschimi K, Frantz JD, Flier JS 1999 The role of SOCS-3 in leptin signaling and leptin resistance. J Biol Chem 274:30059-30065
    • (1999) J Biol Chem , vol.274 , pp. 30059-30065
    • Bjorbaek, C.1    El Haschimi, K.2    Frantz, J.D.3    Flier, J.S.4
  • 33
  • 35
  • 36
    • 0034703097 scopus 로고    scopus 로고
    • CIS3/SOCS3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2
    • Sasaki A, Yasukawa H, Shouda T, Kitamura T, Dikic I, Yoshimura A 2000 CIS3/SOCS3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2. J Biol Chem 275:29338-29347
    • (2000) J Biol Chem , vol.275 , pp. 29338-29347
    • Sasaki, A.1    Yasukawa, H.2    Shouda, T.3    Kitamura, T.4    Dikic, I.5    Yoshimura, A.6
  • 37
    • 0032803530 scopus 로고    scopus 로고
    • Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
    • Sasaki A, Yasukawa H, Suzuki A, Kamizono S, Syoda T, Kinjyo I, Sasaki M, Johnston JA, Yoshimura A 1999 Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells 4:339-351
    • (1999) Genes Cells , vol.4 , pp. 339-351
    • Sasaki, A.1    Yasukawa, H.2    Suzuki, A.3    Kamizono, S.4    Syoda, T.5    Kinjyo, I.6    Sasaki, M.7    Johnston, J.A.8    Yoshimura, A.9
  • 40
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI 1998 Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394:897-901
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 42
    • 3142782772 scopus 로고    scopus 로고
    • Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
    • Howard JK, Cave BJ, Oksanen LJ, Tzameli I, Bjorbaek C, Flier JS 2004 Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. Nat Med 10:734-738
    • (2004) Nat Med , vol.10 , pp. 734-738
    • Howard, J.K.1    Cave, B.J.2    Oksanen, L.J.3    Tzameli, I.4    Bjorbaek, C.5    Flier, J.S.6
  • 44
    • 0030049783 scopus 로고    scopus 로고
    • Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
    • Bennett AM, Hausdorff SF, O'Reilly AM, Freeman RM, Neel BG 1996 Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol Cell Biol 16:1189-1202
    • (1996) Mol Cell Biol , vol.16 , pp. 1189-1202
    • Bennett, A.M.1    Hausdorff, S.F.2    O'Reilly, A.M.3    Freeman, R.M.4    Neel, B.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.