Structural study of the complex stereoselectivity of human butyrylcholinesterase for the neurotoxic V-agents

Journal of Biological Chemistry

Volumn 286, Issue 19, 2011, Pages 16783-16789

  Wandhammer, Marielle ^a,b   Carletti, Eugénie ^a   Van Der Schans, Marcel ^c   Gillon, Emilie ^a   Nicolet, Yvain ^d   Masson, Patrick ^a   Goeldner, Maurice ^b   Noort, Daan ^c   Nachon, Florian ^a  

^a INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

^b Faculté de Pharmacie   (France)

^c TNO   (Netherlands)

^d INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; STEREOSELECTIVITY;

ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTERASE; CHOLINERGIC SYSTEMS; ORGANOPHOSPHATE COMPOUNDS; STRUCTURAL STUDIES; THREE-DIMENSIONAL DATA; THREE-DIMENSIONAL STRUCTURE; TIME-DEPENDENT PROCESS;

ENANTIOMERS;

CHOLINESTERASE; DIETHYLAMINO ETHYL O BUTYL METHYLPHOSPHONOTHIOATE; DIETHYLAMINO ETHYL O ISOBUTYL METHYLPHOSPHONOTHIOATE; DIISOPROPYLAMINO ETHYL O ETHYL METHYLPHOSPHONOTHIOATE; ORGANOPHOSPHORUS COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENANTIOMER; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

EID: 79955773724     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.209569     Document Type: Article

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