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Volumn 121, Issue 42, 1999, Pages 9883-9884

Reaction products of acetylcholinesterase and VX reveal a mobile histidine in the catalytic triad [7]

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ASPARAGINE; GLUTAMINE; HISTIDINE; SERINE; SERINE PROTEINASE;

EID: 0033610449     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja992704i     Document Type: Letter
Times cited : (151)

References (19)
  • 5
    • 13044303121 scopus 로고    scopus 로고
    • note
    • DFP, diisopropylphosphorofluoridate; sarin, O-isopropylmethylphosphonofluoridate; soman, O-pinacolyl methylphosphonofluoridate.
  • 8
    • 0025778840 scopus 로고
    • 121 were prepared in PEG-200, pH 6.0, and data were collected at 100 K with synchrotron radiation at Elletra, Trieste (1vxr) or Broohaven National Laboratory, NY (1vxo). All crystals were isomorphous with native TcAChE (2ace); see ref 5 and Sussman, J. L.; Harel, M.; Frolow, F.; Oefner, C.; Goldman, A.; Toker, L.; and Silman, I. Science 1991, 253, 872-879. The final R-factors were 18.9% (1vxr) and 19.4% (1vxo), and the free-R-factors were 23.0% (1vxr) and 23.4% (1vxo).
    • (1991) Science , vol.253 , pp. 872-879
    • Sussman, J.L.1    Harel, M.2    Frolow, F.3    Oefner, C.4    Goldman, A.5    Toker, L.6    Silman, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.