Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: A kinetic analysis

Toxicology

Volumn 259, Issue 3, 2009, Pages 133-139

  Aurbek, N ^a   Thiermann, H ^a   Eyer, F ^b   Eyer, P ^c   Worek, F ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Butyrylcholinesterase; Human poisoning; Organophosphorus compounds; Oximes; Scavenger; Therapeutic drug monitoring

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 [[[4 (AMINOCARBONYL)PYRIDINIO] METHOXY] METHYL] 2 [(HYDROXYIMINO)METHYL]PYRIDINIUM DICHLORIDE MONOHYDRATE; 1,1' METHYLENE BIS[4 (HYDROXYIMINO)METHYL] PYRIDINIUM DICHLORIDE; ACETYLCHOLINESTERASE; ATROPINE; CHOLINERGIC RECEPTOR; CHOLINESTERASE; DIMETHOATE; OBIDOXIME; ORGANOPHOSPHATE; OXIME; PESTICIDE; PRALIDOXIME; SCAVENGER; SOMAN; TABUN; UNCLASSIFIED DRUG;

ARMY; ARTICLE; CATALYSIS; CHOLINESTERASE BLOOD LEVEL; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONFLICT; DISEASE MARKER; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ERYTHROCYTE; EXPERIMENTAL STUDY; HUMAN; IN VITRO STUDY; INTOXICATION; KINETICS; LABORATORY TEST; MEASUREMENT; MENTAL HEALTH; MONITORING; NERVE; PARAMETER; PRIORITY JOURNAL; PROFESSIONAL PRACTICE; STIMULATION; STOICHIOMETRY; SYMPTOMATOLOGY; SYNAPSE; TERRORISM;

ACETYLCHOLINESTERASE; BIOLOGICAL MARKERS; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ERYTHROCYTE MEMBRANE; HUMANS; KINETICS; OBIDOXIME CHLORIDE; ORGANOPHOSPHORUS COMPOUNDS; OXIMES; PESTICIDES; PRALIDOXIME COMPOUNDS; PYRIDINIUM COMPOUNDS;

EID: 63449083967     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.02.014     Document Type: Article

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