Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis

PLoS Biology

Volumn 9, Issue 4, 2011, Pages

  Lazaridis, Iakovos ^a   Charalampopoulos, Ioannis ^a   Alexaki, Vassilia Ismini ^a   Avlonitis, Nicolaos ^b   Pediaditakis, Iosif ^a   Efstathopoulos, Paschalis ^a   Calogeropoulou, Theodora ^b   Castanas, Elias ^a   Gravanis, Achille ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GENE PRODUCT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN; NEUROTROPHIN RECEPTOR P75; PRASTERONE; PROTEIN KINASE B; PROTEIN RIP2; PROTEIN SHC; PROTEIN TYROSINE KINASE A; RHOGDI PROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; NERVE PROTEIN; NGFR PROTEIN, HUMAN; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL STRAIN HEK293; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MEMBRANE BINDING; NERVE CELL MEMBRANE; NEUROPROTECTION; NONHUMAN; PHYLOGENY; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE CELL; ANIMAL; C57BL MOUSE; CELL STRAIN; GENETICS; METABOLISM; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; DEHYDROEPIANDROSTERONE; HEK293 CELLS; HUMANS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEUROGENESIS; NEURONS; PC12 CELLS; PHOSPHORYLATION; PHYLOGENY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 79955514139     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001051     Document Type: Article

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