Neurosteroid dehydroepiandrosterone exerts anti-apoptotic effects by membrane-mediated, integrated genomic and non-genomic pro-survival signaling pathways

Journal of Neurochemistry

Volumn 107, Issue 5, 2008, Pages 1457-1469

  Charalampopoulos, Ioannis ^a   Margioris, Andrew N ^a   Gravanis, Achille ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Apoptosis; Bcl 2; Neurosteroids; Prosurvival kinases; Signaling

Indexed keywords

BOVINE SERUM ALBUMIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PRASTERONE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL LEVEL; CELL MEMBRANE; CELL PROTECTION; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENOMICS; HORMONE ACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEHYDROEPIANDROSTERONE; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENOMICS; HIPPOCAMPUS; MODELS, BIOLOGICAL; NF-KAPPA B; PC12 CELLS; PERTUSSIS TOXIN; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

BOVINAE;

EID: 55849139115     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05732.x     Document Type: Article

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