Nerve growth factor stimulation of p42/p44 mitogen-activated protein kinase in PC12 cells: Role of Gi/o, G protein-coupled receptor kinase 2, β-arrestin I, and endocytic processing

Molecular Pharmacology

Volumn 60, Issue 1, 2001, Pages 63-70

  Rakhit, Soma ^a   Pyne, Susan ^a   Pyne, Nigel J ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PERTUSSIS TOXIN; PROTEIN P42; PROTEIN P44;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; DRUG MECHANISM; ENDOCYTOSIS; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0034952792     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.1.63     Document Type: Article

References (18)

1. Src-mediated tyrosine phosphorylation of dynamic is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
2. Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: Role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase
3. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
4. Role of transactivation of the EGF receptor in signalling by G-protein coupled receptors
5. Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis toxin-sensitive G proteins
6. i with insulin growth factor-1 receptor. Release of Gβγ subunits upon receptor activation
7. Signal transduction by the neurotrophin receptors
8. Gab1 mediates neurite outgrowths, DNA synthesis, and survival in PC12 cells
9. Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascade in vascular smooth muscle cells
10. β-Arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor
11. A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes
12. βγ subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor
13. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
14. Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: Role of endothelial differentiation gene-1, c-Src tyrosine kinase and phosphoinositide 3-kinase
15. The platelet-derived growth factor stimulation of p42/p44 mitogen-activated protein kinase in airway smooth muscle involves a G-protein-mediated tyrosine phosphorylation of Gab1
16. Insulin inhibits pertussis toxin-catalyzed ADP-ribosylation of G-proteins. Evidence for a novel interaction between insulin receptors and G-proteins
17. The mitogen-activated protein (MAP) protein kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic
18. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor