-
1
-
-
77649126524
-
Heart disease and stroke statistics - 2010 update: A report from the American Heart Association
-
Lloyd-Jones D, Adams RJ, Brown TM et al. Heart disease and stroke statistics - 2010 update: a report from the American Heart Association. Circulation 121(7), e46-e215 (2010).
-
(2010)
Circulation
, vol.121
, Issue.7
-
-
Lloyd-Jones, D.1
Adams, R.J.2
Brown, T.M.3
-
2
-
-
70449632804
-
Costs and rehabilitation use of stroke survivors: A retrospective study of Medicare beneficiaries
-
Zorowitz RD, Chen E, Tong KB, Laouri M. Costs and rehabilitation use of stroke survivors: a retrospective study of Medicare beneficiaries. Top Stroke Rehabil. 16(5), 309-320 (2009).
-
(2009)
Top Stroke Rehabil.
, vol.16
, Issue.5
, pp. 309-320
-
-
Zorowitz, R.D.1
Chen, E.2
Tong, K.B.3
Laouri, M.4
-
3
-
-
0034983276
-
Trends in acute ischemic stroke trials through the 20th century
-
Kidwell CS, Liebeskind DS, Starkman S, Saver JL. Trends in acute ischemic stroke trials through the 20th Century. Stroke 32(6), 1349-1359 (2001). (Pubitemid 32530421)
-
(2001)
Stroke
, vol.32
, Issue.6
, pp. 1349-1359
-
-
Kidwell, C.S.1
Liebeskind, D.S.2
Starkman, S.3
Saver, J.L.4
-
4
-
-
0036330007
-
Toward wisdom from failure: Lessons from neuroprotective stroke trials and new therapeutic directions
-
DOI 10.1161/01.STR.0000025518.34157.51
-
Gladstone DJ, Black SE, Hakim AM. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 33(8), 2123-2136 (2002). (Pubitemid 34840080)
-
(2002)
Stroke
, vol.33
, Issue.8
, pp. 2123-2136
-
-
Gladstone, D.J.1
Black, S.E.2
Hakim, A.M.3
-
5
-
-
33644818304
-
1,026 Experimental treatments in acute stroke
-
DOI 10.1002/ana.20741
-
O'Collins VE, Macleod MR, Donnan GA, Horky LL, van Der Worp BH, Howells DW. 1,026 experimental treatments in acute stroke. Ann. Neurol. 59(3), 467-477 (2006). (Pubitemid 43358067)
-
(2006)
Annals of Neurology
, vol.59
, Issue.3
, pp. 467-477
-
-
O'Collins, V.E.1
Macleod, M.R.2
Donnan, G.A.3
Horky, L.L.4
Van Der Worp, B.H.5
Howells, D.W.6
-
6
-
-
26844435654
-
Rodent models of focal stroke: Size, mechanism, and purpose
-
DOI 10.1602/neurorx.2.3.396
-
Carmichael ST. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2(3), 396-409 (2005). (Pubitemid 41444874)
-
(2005)
NeuroRx
, vol.2
, Issue.3
, pp. 396-409
-
-
Carmichael, S.T.1
-
7
-
-
0032825279
-
Pharmacological approaches to stroke recovery
-
Fisher M, Finklestein S. Pharmacological approaches to stroke recovery. Cerebrovasc. Dis. 9(Suppl. 5), 29-32 (1999). (Pubitemid 29410706)
-
(1999)
Cerebrovascular Diseases
, vol.9
, Issue.SUPPL. 5
, pp. 29-32
-
-
Fisher, M.1
Finklestein, S.2
-
8
-
-
77955171934
-
Different strokes for different folks: The rich diversity of animal models of focal cerebral ischemia
-
Howells DW, Porritt MJ, Rewell SS et al. Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia. J. Cereb. Blood Flow Metab. 30(8), 1412-1431 (2010).
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, Issue.8
, pp. 1412-1431
-
-
Howells, D.W.1
Porritt, M.J.2
Rewell, S.S.3
-
9
-
-
2142768247
-
Pooling of animal experimental data reveals influence of study design and publication bias
-
DOI 10.1161/01.STR.0000125719.25853.20
-
Macleod MR, O'collins T, Howells DW, Donnan GA. Pooling of animal experimental data reveals influence of study design and publication bias. Stroke 35(5), 1203-1208 (2004). (Pubitemid 38543544)
-
(2004)
Stroke
, vol.35
, Issue.5
, pp. 1203-1208
-
-
Macleod, M.R.1
O'Collins, T.2
Howells, D.W.3
Donnan, G.A.4
-
10
-
-
0344065373
-
Recommendations for standards regarding preclinical neuroprotective and restorative drug development
-
STAIR
-
STAIR. Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30(12), 2752-2758 (1999).
-
(1999)
Stroke
, vol.30
, Issue.12
, pp. 2752-2758
-
-
-
11
-
-
66849097996
-
Update of the stroke therapy academic industry roundtable preclinical recommendations
-
Fisher M, Feuerstein G, Howells DW et al. Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke 40(6), 2244-2250 (2009).
-
(2009)
Stroke
, vol.40
, Issue.6
, pp. 2244-2250
-
-
Fisher, M.1
Feuerstein, G.2
Howells, D.W.3
-
12
-
-
10844282711
-
Nitrone-related therapeutics: Potential of NXY-059 for the treatment of acute ischaemic stroke
-
DOI 10.2165/00023210-200418150-00003
-
Maples KR, Green AR, Floyd RA. Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke. CNS Drugs 18(15), 1071-1084 (2004). (Pubitemid 40007491)
-
(2004)
CNS Drugs
, vol.18
, Issue.15
, pp. 1071-1084
-
-
Maples, K.R.1
Green, A.R.2
Floyd, R.A.3
-
13
-
-
33749017039
-
NXY-059: A hopeful sign in the treatment of stroke
-
DOI 10.1161/01.STR.0000240511.22775.a7, PII 0000767020061000000045
-
Hess DC. NXY-059: a hopeful sign in the treatment of stroke. Stroke 37(10), 2649-2650 (2006). (Pubitemid 44454696)
-
(2006)
Stroke
, vol.37
, Issue.10
, pp. 2649-2650
-
-
Hess, D.C.1
-
14
-
-
0037253099
-
Assessment of cognitive and motor deficits in a marmoset model of stroke
-
Marshall JW, Ridley RM. Assessment of cognitive and motor deficits in a marmoset model of stroke. ILAR J. 44(2), 153-160 (2003). (Pubitemid 36410969)
-
(2003)
ILAR Journal
, vol.44
, Issue.2
, pp. 153-160
-
-
Marshall, J.W.B.1
Ridley, R.M.2
-
15
-
-
0141608602
-
Serial MRI, functional recovery, and long-term infarct maturation in a non-human primate model of stroke
-
DOI 10.1016/S0361-9230(03)00214-4
-
Marshall JW, Ridley RM, Baker HF, Hall LD, Carpenter TA, Wood NI. Serial MRI, functional recovery, and long-term infarct maturation in a non-human primate model of stroke. Brain Res. Bull. 61(6), 577-585 (2003). (Pubitemid 37168092)
-
(2003)
Brain Research Bulletin
, vol.61
, Issue.6
, pp. 577-585
-
-
Marshall, J.W.B.1
Ridley, R.M.2
Baker, H.F.3
Hall, L.D.4
Carpenter, T.A.5
Wood, N.I.6
-
16
-
-
0035154631
-
NXY-059, a free radical-trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species
-
Marshall JW, Duffin KJ, Green AR, Ridley RM. NXY-059, a free radical - trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species. Stroke 32(1), 190-198 (2001). (Pubitemid 32063845)
-
(2001)
Stroke
, vol.32
, Issue.1
, pp. 190-198
-
-
Marshall, J.W.B.1
Duffin, K.J.2
Green, A.R.3
Ridley, R.M.4
-
17
-
-
0042919342
-
Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion
-
DOI 10.1161/01.STR.0000087790.79851.A8
-
Marshall JW, Cummings RM, Bowes LJ, Ridley RM, Green AR. Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion. Stroke 34(9), 2228-2233 (2003). (Pubitemid 37099841)
-
(2003)
Stroke
, vol.34
, Issue.9
, pp. 2228-2233
-
-
Marshall, J.W.B.1
Cummings, R.M.2
Bowes, L.J.3
Ridley, R.M.4
Green, A.R.5
-
18
-
-
0242501513
-
Comparison of the neuroprotective effect of clomethiazole, AR-R15896AR and NXY-059 in a primate model of stroke using histological and behavioural measures
-
DOI 10.1016/S0006-8993(03)02511-3
-
Marshall JW, Green AR, Ridley RM. Comparison of the neuroprotective effect of clomethiazole, AR-R15896AR and NXY-059 in a primate model of stroke using histological and behavioural measures. Brain Res. 972(1-2), 119-126 (2003). (Pubitemid 36507083)
-
(2003)
Brain Research
, vol.972
, Issue.1-2
, pp. 119-126
-
-
Marshall, J.W.B.1
Green, A.R.2
Ridley, R.M.3
-
19
-
-
32144453826
-
NXY-059 for acute ischemic stroke
-
DOI 10.1056/NEJMoa052980
-
Lees KR, Zivin JA, Ashwood T et al. NXY-059 for acute ischemic stroke. N. Engl. J. Med. 354(6), 588-600 (2006). (Pubitemid 43209106)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.6
, pp. 588-600
-
-
Lees, K.R.1
Zivin, J.A.2
Ashwood, T.3
Davalos, A.4
Davis, S.M.5
Diener, H.-C.6
Grotta, J.7
Lyden, P.8
Shuaib, A.9
Hardemark, H.-G.10
Wasiewski, W.W.11
-
20
-
-
34547795720
-
NXY-059 for the treatment of acute ischemic stroke
-
DOI 10.1056/NEJMoa070240
-
Shuaib A, Lees KR, Lyden P et al. NXY-059 for the treatment of acute ischemic stroke. N. Engl. J. Med. 357(6), 562-571 (2007). (Pubitemid 47236281)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.6
, pp. 562-571
-
-
Shuaib, A.1
Lees, K.R.2
Lyden, P.3
Grotta, J.4
Davalos, A.5
Davis, S.M.6
Diener, H.-C.7
Ashwood, T.8
Wasiewski, W.W.9
Emeribe, U.10
-
21
-
-
46249131138
-
NXY-059 for the treatment of acute stroke: Pooled analysis of the SAINT I and II Trials
-
Diener HC, Lees KR, Lyden P et al. NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials. Stroke 39(6), 1751-1758 (2008).
-
(2008)
Stroke
, vol.39
, Issue.6
, pp. 1751-1758
-
-
Diener, H.C.1
Lees, K.R.2
Lyden, P.3
-
22
-
-
33751327483
-
Bench to bedside: The quest for quality in experimental stroke research
-
DOI 10.1038/sj.jcbfm.9600298, PII 9600298
-
Dirnagl U. Bench to bedside: the quest for quality in experimental stroke research. J. Cereb. Blood Flow Metab. 26(12), 1465-1478 (2006). (Pubitemid 44809076)
-
(2006)
Journal of Cerebral Blood Flow and Metabolism
, vol.26
, Issue.12
, pp. 1465-1478
-
-
Dirnagl, U.1
-
23
-
-
34249942190
-
Future of neuroprotection for acute stroke: In the aftermath of the SAINT trials
-
DOI 10.1002/ana.21127
-
Savitz SI, Fisher M. Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials. Ann. Neurol. 61(5), 396-402 (2007). (Pubitemid 46878767)
-
(2007)
Annals of Neurology
, vol.61
, Issue.5
, pp. 396-402
-
-
Savitz, S.I.1
Fisher, M.2
-
24
-
-
60549107281
-
Methodological quality of animal studies of neuroprotective agents currently in Phase II/III acute ischemic stroke trials
-
Philip M, Benatar M, Fisher M, Savitz SI. Methodological quality of animal studies of neuroprotective agents currently in Phase II/III acute ischemic stroke trials. Stroke 40(2), 577-581 (2009).
-
(2009)
Stroke
, vol.40
, Issue.2
, pp. 577-581
-
-
Philip, M.1
Benatar, M.2
Fisher, M.3
Savitz, S.I.4
-
25
-
-
34247263212
-
A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: A need for more rigorous testing of neuroprotective agents in animal models of stroke
-
DOI 10.1016/j.expneurol.2007.03.003, PII S0014488607000970
-
Savitz SI. A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke. Exp. Neurol. 205(1), 20-25 (2007). (Pubitemid 46621180)
-
(2007)
Experimental Neurology
, vol.205
, Issue.1
, pp. 20-25
-
-
Savitz, S.I.1
-
26
-
-
0141688316
-
Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line
-
Liu Y, Song XD, Liu W, Zhang TY, Zuo J. Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line. J. Cell Mol. Med. 7(1), 49-56 (2003). (Pubitemid 37123376)
-
(2003)
Journal of Cellular and Molecular Medicine
, vol.7
, Issue.1
, pp. 49-56
-
-
Liu, Y.1
Song, X.-D.2
Liu, W.3
Zhang, T.-Y.4
Zuo, J.5
-
27
-
-
0031024098
-
Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro
-
DOI 10.1210/en.138.1.101
-
Behl C, Lezoualc'h F, Trapp T, Widmann M, Skutella T, Holsboer F. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology 138(1), 101-106 (1997). (Pubitemid 27009411)
-
(1997)
Endocrinology
, vol.138
, Issue.1
, pp. 101-106
-
-
Behl, C.1
Lezoualc'h, F.2
Trapp, T.3
Widmann, M.4
Skutella, T.5
Holsboer, F.6
-
28
-
-
0015447985
-
Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures
-
Booher J, Sensenbrenner M. Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology 2(3), 97-105 (1972).
-
(1972)
Neurobiology
, vol.2
, Issue.3
, pp. 97-105
-
-
Booher, J.1
Sensenbrenner, M.2
-
29
-
-
0027328680
-
Combined oxygen and glucose deprivation in cortical cell culture: Calcium- dependent and calcium-independent mechanisms of neuronal injury
-
Goldberg MP, Choi DW. Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J. Neurosci. 13(8), 3510-3524 (1993). (Pubitemid 23241187)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.8
, pp. 3510-3524
-
-
Goldberg, M.P.1
Choi, D.W.2
-
30
-
-
0028804835
-
Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures
-
Newell DW, Barth A, Papermaster V, Malouf AT. Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. J. Neurosci. 15(11), 7702-7711 (1995).
-
(1995)
J. Neurosci.
, vol.15
, Issue.11
, pp. 7702-7711
-
-
Newell, D.W.1
Barth, A.2
Papermaster, V.3
Malouf, A.T.4
-
31
-
-
0028902855
-
Quantitative measurement of neuronal degeneration in organotypic hippocampal cultures after combined oxygen/glucose deprivation
-
Strasser U, Fischer G. Quantitative measurement of neuronal degeneration in organotypic hippocampal cultures after combined oxygen/glucose deprivation. J. Neurosci. Methods 57(2), 177-186 (1995).
-
(1995)
J. Neurosci. Methods
, vol.57
, Issue.2
, pp. 177-186
-
-
Strasser, U.1
Fischer, G.2
-
32
-
-
0033555423
-
Oxygen/glucose deprivation in hippocampal slices: Altered intraneuronal elemental composition predicts structural and functional damage
-
Taylor CP, Weber ML, Gaughan CL, Lehning EJ, Lopachin RM. Oxygen/ glucose deprivation in hippocampal slices: altered intraneuronal elemental composition predicts structural and functional damage. J. Neurosci. 19(2), 619-629 (1999). (Pubitemid 29036013)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.2
, pp. 619-629
-
-
Taylor, C.P.1
Weber, M.L.2
Gaughan, C.L.3
Lehning, E.J.4
LoPachin, R.M.5
-
33
-
-
85056069766
-
Animal models of ischemic stroke. Part two: Modeling cerebral ischemia
-
Bacigaluppi M, Comi G, Hermann DM. Animal models of ischemic stroke. Part two: modeling cerebral ischemia. Open Neurol. J. 4, 34-38 (2010).
-
(2010)
Open Neurol. J.
, vol.4
, pp. 34-38
-
-
Bacigaluppi, M.1
Comi, G.2
Hermann, D.M.3
-
34
-
-
22044448897
-
Organotypic cultures as tools for functional screening in the CNS
-
DOI 10.1016/S1359-6446(05)03502-6, PII S1359644605035026
-
Sundstrom L, Morrison B 3rd, Bradley M, Pringle A. Organotypic cultures as tools for functional screening in the CNS. Drug Discov. Today 10(14), 993-1000 (2005). (Pubitemid 40967048)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.14
, pp. 993-1000
-
-
Sundstrom, L.1
Morrison III, B.2
Bradley, M.3
Pringle, A.4
-
35
-
-
62949129784
-
Translational medicine for stroke drug discovery: The pharmaceutical industry perspective
-
Feuerstein GZ, Chavez J. Translational medicine for stroke drug discovery: the pharmaceutical industry perspective. Stroke 40(Suppl. 3), S121-S125 (2009).
-
(2009)
Stroke
, vol.40
, Issue.SUPPL. 3
-
-
Feuerstein, G.Z.1
Chavez, J.2
-
36
-
-
0029175202
-
Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
-
Mattson MP, Barger SW, Begley JG, Mark RJ. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46, 187-216 (1995).
-
(1995)
Methods Cell Biol.
, vol.46
, pp. 187-216
-
-
Mattson, M.P.1
Barger, S.W.2
Begley, J.G.3
Mark, R.J.4
-
37
-
-
0036447440
-
Oxidative stress and cyclooxygenase-2 induction mediate cyanide-induced apoptosis of cortical cells
-
DOI 10.1006/taap.2002.9515
-
Li L, Prabhakaran K, Shou Y, Borowitz JL, Isom GE. Oxidative stress and cyclooxygenase-2 induction mediate cyanide-induced apoptosis of cortical cells. Toxicol. Appl. Pharmacol. 185(1), 55-63 (2002). (Pubitemid 35425697)
-
(2002)
Toxicology and Applied Pharmacology
, vol.185
, Issue.1
, pp. 55-63
-
-
Li, L.1
Prabhakaran, K.2
Shou, Y.3
Borowitz, J.L.4
Isom, G.E.5
-
38
-
-
77955570062
-
Glutamate receptors, neurotoxicity and neurodegeneration
-
Lau A, Tymianski M. Glutamate receptors, neurotoxicity and neurodegeneration. Pflugers Arch. 460(2), 525-542 (2010).
-
(2010)
Pflugers Arch.
, vol.460
, Issue.2
, pp. 525-542
-
-
Lau, A.1
Tymianski, M.2
-
39
-
-
77549083577
-
Calcium, ischemia and excitotoxicity
-
Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium 47(2), 122-129 (2010).
-
(2010)
Cell Calcium
, vol.47
, Issue.2
, pp. 122-129
-
-
Szydlowska, K.1
Tymianski, M.2
-
41
-
-
0029820948
-
+ changes induced by glutamate, kainate, and D- aspartate in rat hippocampal astrocytes
-
Rose CR, Ransom BR. Mechanisms of H+ and Na+ changes induced by glutamate, kainate, and d-aspartate in rat hippocampal astrocytes. J. Neurosci. 16(17), 5393-5404 (1996). (Pubitemid 26277868)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.17
, pp. 5393-5404
-
-
Rose, C.R.1
Ransom, B.R.2
-
42
-
-
0032078116
-
AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization
-
DOI 10.1016/S0197-0186(97)00130-7, PII S0197018697001307
-
Jensen JB, Schousboe A, Pickering DS. AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization. Neurochem. Int. 32(5-6), 505-513 (1998). (Pubitemid 28287204)
-
(1998)
Neurochemistry International
, vol.32
, Issue.5-6
, pp. 505-513
-
-
Jensen, J.B.1
Schousboe, A.2
Pickering, D.S.3
-
43
-
-
40949114131
-
The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures
-
Lau AC, Cui H, Tymianski M. The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. Methods Mol. Biol. 399, 15-29 (2007).
-
(2007)
Methods Mol. Biol.
, vol.399
, pp. 15-29
-
-
Lau, A.C.1
Cui, H.2
Tymianski, M.3
-
44
-
-
0030852948
-
Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) reduction
-
Liu Y, Peterson DA, Kimura H, Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) reduction J. Neurochem. 69(2), 581-593 (1997). (Pubitemid 27327958)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.2
, pp. 581-593
-
-
Liu, Y.1
Peterson, D.A.2
Kimura, H.3
Schubert, D.4
-
45
-
-
0023545249
-
PC12 pheochromocytoma cells: Culture, nerve growth factor treatment, and experimental exploitation
-
Greene LA, Aletta JM, Rukenstein A, Green SH. PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Methods Enzymol. 147, 207-216 (1987). (Pubitemid 18013020)
-
(1987)
Methods in Enzymology
, vol.147
, pp. 207-216
-
-
Greene, L.A.1
Aletta, J.M.2
Rukenstein, A.3
Green, S.H.4
-
46
-
-
0030273118
-
Ischemia-induced neuronal apoptosis
-
DOI 10.1016/S0959-4388(96)80101-2
-
Choi DW. Ischemia-induced neuronal apoptosis. Curr. Opin. Neurobiol. 6(5), 667-672 (1996). (Pubitemid 26387723)
-
(1996)
Current Opinion in Neurobiology
, vol.6
, Issue.5
, pp. 667-672
-
-
Choi, D.W.1
-
47
-
-
0028882764
-
Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-d-aspartate
-
Dugan LL, Sensi SL, Canzoniero LM et al. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-d-aspartate. J. Neurosci. 15(10), 6377-6388 (1995).
-
(1995)
J. Neurosci.
, vol.15
, Issue.10
, pp. 6377-6388
-
-
Dugan, L.L.1
Sensi, S.L.2
Canzoniero, L.M.3
-
48
-
-
65449153299
-
A novel in vitro ischemia/reperfusion injury model
-
Lee WH, Kang S, Vlachos PP, Lee YW. A novel in vitro ischemia/reperfusion injury model. Arch. Pharm. Res. 32(3), 421-429 (2009).
-
(2009)
Arch. Pharm. Res.
, vol.32
, Issue.3
, pp. 421-429
-
-
Lee, W.H.1
Kang, S.2
Vlachos, P.P.3
Lee, Y.W.4
-
49
-
-
35848949798
-
Cell-cell signaling in the neurovascular unit
-
DOI 10.1007/s11064-007-9342-9
-
Lok J, Gupta P, Guo S et al. Cell-cell signaling in the neurovascular unit. Neurochem. Res. 32(12), 2032-2045 (2007). (Pubitemid 350059847)
-
(2007)
Neurochemical Research
, vol.32
, Issue.12
, pp. 2032-2045
-
-
Lok, J.1
Gupta, P.2
Guo, S.3
Kim, W.J.4
Whalen, M.J.5
Van Leyen, K.6
Lo, E.H.7
-
50
-
-
0032261713
-
Understanding the physiology of the blood-brain barrier: In vitro models
-
Grant GA, Abbott NJ, Janigro D. Understanding the physiology of the blood-brain barrier: in vitro models. News Physiol. Sci. 13, 287-293 (1998).
-
(1998)
News Physiol. Sci.
, vol.13
, pp. 287-293
-
-
Grant, G.A.1
Abbott, N.J.2
Janigro, D.3
-
51
-
-
77951527968
-
Comparison of two blood-brain barrier in vitro systems: Cytotoxicity and transfer assessments of malathion/oxon and lead acetate
-
Balbuena P, Li W, Magnin-Bissel G, Meldrum JB, Ehrich M. Comparison of two blood-brain barrier in vitro systems: cytotoxicity and transfer assessments of malathion/oxon and lead acetate. Toxicol. Sci. 114(2), 260-271 (2010).
-
(2010)
Toxicol. Sci.
, vol.114
, Issue.2
, pp. 260-271
-
-
Balbuena, P.1
Li, W.2
Magnin-Bissel, G.3
Meldrum, J.B.4
Ehrich, M.5
-
52
-
-
29144533824
-
Organotypic hippocampal slice cultures: A model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity
-
DOI 10.1007/s11064-005-8829-5
-
Holopainen IE. Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity. Neurochem. Res. 30(12), 1521-1528 (2005). (Pubitemid 41813716)
-
(2005)
Neurochemical Research
, vol.30
, Issue.12
, pp. 1521-1528
-
-
Holopainen, I.E.1
-
53
-
-
23144445999
-
Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair
-
DOI 10.2174/1568007054546108
-
Noraberg J, Poulsen FR, Blaabjerg M et al. Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair. Curr. Drug Targets CNS Neurol. Disord. 4(4), 435-452 (2005). (Pubitemid 41086760)
-
(2005)
Current Drug Targets: CNS and Neurological Disorders
, vol.4
, Issue.4
, pp. 435-452
-
-
Noraberg, J.1
Poulsen, F.R.2
Blaabjerg, M.3
Kristensen, B.W.4
Bonde, C.5
Montero, M.6
Meyer, M.7
Gramsbergen, J.B.8
Zimmer, J.9
-
54
-
-
13544251757
-
Mechanisms of Neural Cell Death: Implications for Development of Neuroprotective Treatment Strategies
-
DOI 10.1602/neurorx.1.1.5, PII S1545534306700037
-
Yakovlev AG, Faden AI. Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies. NeuroRx 1(1), 5-16 (2004). (Pubitemid 46589338)
-
(2004)
NeuroRx
, vol.1
, Issue.1
, pp. 5-16
-
-
Yakovlev, A.G.1
Faden, A.I.2
-
55
-
-
0037268227
-
Neuroprotective gene therapy against acute neurological insults
-
DOI 10.1038/nrn1006
-
Sapolsky RM. Neuroprotective gene therapy against acute neurological insults. Nat. Rev. Neurosci. 4(1), 61-69 (2003). (Pubitemid 37271089)
-
(2003)
Nature Reviews Neuroscience
, vol.4
, Issue.1
, pp. 61-69
-
-
Sapolsky, R.M.1
-
56
-
-
65749097049
-
In vivo gene regulation using tetracycline-regulatable systems
-
Stieger K, Belbellaa B, Le Guiner C, Moullier P, Rolling F. In vivo gene regulation using tetracycline-regulatable systems. Adv. Drug Deliv. Rev. 61(7-8), 527-541 (2009).
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, Issue.7-8
, pp. 527-541
-
-
Stieger, K.1
Belbellaa, B.2
Le Guiner, C.3
Moullier, P.4
Rolling, F.5
-
57
-
-
34548636072
-
PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors
-
DOI 10.1523/JNEUROSCI.1464-07.2007
-
Cui H, Hayashi A, Sun HS et al. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J. Neurosci. 27(37), 9901-9915 (2007). (Pubitemid 47404012)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.37
, pp. 9901-9915
-
-
Cui, H.1
Hayashi, A.2
Sun, H.-S.3
Belmares, M.P.4
Cobey, C.5
Phan, T.6
Schweizer, J.7
Salter, M.W.8
Yu, T.W.9
Tasker, R.A.10
Garman, D.11
Rabinowitz, J.12
Lu, P.S.13
Tymianski, M.14
-
58
-
-
33947288475
-
Ischaemic brain damage after stroke: New insights into efficient therapeutic strategies. International Symposium on Neurodegeneration and Neuroprotection
-
DOI 10.1038/sj.embor.7400892, PII 7400892
-
Culmsee C, Krieglstein J. Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies. International Symposium on Neurodegeneration and Neuroprotection. EMBO Rep. 8(2), 129-133 (2007). (Pubitemid 46420838)
-
(2007)
EMBO Reports
, vol.8
, Issue.2
, pp. 129-133
-
-
Culmsee, C.1
Krieglstein, J.2
-
59
-
-
0033546347
-
Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
-
Sattler R, Xiong Z, Lu WY, Hafner M, Macdonald JF, Tymianski M. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 284(5421), 1845-1848 (1999).
-
(1999)
Science
, vol.284
, Issue.5421
, pp. 1845-1848
-
-
Sattler, R.1
Xiong, Z.2
Lu, W.Y.3
Hafner, M.4
MacDonald, J.F.5
Tymianski, M.6
-
60
-
-
0037174635
-
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
-
DOI 10.1126/science.1072873
-
Aarts M, Liu Y, Liu L et al. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science 298(5594), 846-850 (2002). (Pubitemid 35231541)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 846-850
-
-
Aarts, M.1
Liu, Y.2
Liu, L.3
Besshoh, S.4
Arundine, M.5
Gurd, J.W.6
Wang, Y.-T.7
Salter, M.W.8
Tymianski, M.9
-
61
-
-
77953270524
-
Rodent models of focal cerebral ischemia: Procedural pitfalls and translational problems
-
Braeuninger S, Kleinschnitz C. Rodent models of focal cerebral ischemia: procedural pitfalls and translational problems. Exp. Transl. Stroke Med. 1, 8 (2009).
-
(2009)
Exp. Transl. Stroke Med.
, vol.1
, pp. 8
-
-
Braeuninger, S.1
Kleinschnitz, C.2
-
62
-
-
0034936407
-
The failure of neuronal protective agents versus the success of thrombolysis in the treatment of ischemic stroke: The predictive value of animal models
-
Jonas S, Aiyagari V, Vieira D, Figueroa M. The failure of neuronal protective agents versus the success of thrombolysis in the treatment of ischemic stroke. The predictive value of animal models. Ann. NY Acad. Sci. 939, 257-267 (2001). (Pubitemid 32620075)
-
(2001)
Annals of the New York Academy of Sciences
, vol.939
, pp. 257-267
-
-
Jonas, S.1
Aiyagari, V.2
Vieira, D.3
Figueroa, M.4
-
63
-
-
0037247702
-
Clinical issues in animal models of stroke and rehabilitation
-
Cramer SC. Clinical issues in animal models of stroke and rehabilitation. ILAR J. 44(2), 83-84 (2003). (Pubitemid 36410961)
-
(2003)
ILAR Journal
, vol.44
, Issue.2
, pp. 83-84
-
-
Cramer, S.C.1
-
64
-
-
0029044195
-
Animal models of acute ischaemic stroke: Can they predict clinically successful neuroprotective drugs?
-
Hunter AJ, Green AR, Cross AJ. Animal models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs? Trends Pharmacol. Sci. 16(4), 123-128 (1995).
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, Issue.4
, pp. 123-128
-
-
Hunter, A.J.1
Green, A.R.2
Cross, A.J.3
-
65
-
-
0037713477
-
Why have so many drugs with stellar results in laboratory stroke models failed in clinical trials? A theory based on allometric relationships
-
Curry SH. Why have so many drugs with stellar results in laboratory stroke models failed in clinical trials? A theory based on allometric relationships. Ann. NY Acad. Sci. 993, 69-74; discussion 79-81 (2003). (Pubitemid 36808433)
-
(2003)
Annals of the New York Academy of Sciences
, vol.993
, pp. 69-74
-
-
Curry, S.H.1
-
66
-
-
85056070875
-
Animal models of ischemic stroke. Part one: Modeling risk factors
-
Bacigaluppi M, Comi G, Hermann DM. Animal models of ischemic stroke. Part one: modeling risk factors. Open Neurol. J. 4, 26-33 (2010).
-
(2010)
Open Neurol. J.
, vol.4
, pp. 26-33
-
-
Bacigaluppi, M.1
Comi, G.2
Hermann, D.M.3
-
67
-
-
3042706276
-
Lost in translation: Taking neuroprotection from animal models to clinical trials
-
DOI 10.1016/j.expneurol.2004.05.008, PII S0014488604001803
-
Hoyte L, Kaur J, Buchan AM. Lost in translation: taking neuroprotection from animal models to clinical trials. Exp. Neurol. 188(2), 200-204 (2004). (Pubitemid 38891581)
-
(2004)
Experimental Neurology
, vol.188
, Issue.2
, pp. 200-204
-
-
Hoyte, L.1
Kaur, J.2
Buchan, A.M.3
-
68
-
-
5444233626
-
Pathophysiology of stroke: Lessons from animal models
-
DOI 10.1023/B:MEBR.0000043966.46964.e6
-
Mergenthaler P, Dirnagl U, Meisel A. Pathophysiology of stroke: lessons from animal models. Metab. Brain Dis. 19(3-4), 151-167 (2004). (Pubitemid 39361178)
-
(2004)
Metabolic Brain Disease
, vol.19
, Issue.3-4
, pp. 151-167
-
-
Mergenthaler, P.1
Dirnagl, U.2
Meisel, A.3
-
69
-
-
0037252395
-
Models of focal cerebral ischemia in the nonhuman primate
-
Fukuda S, Del Zoppo GJ. Models of focal cerebral ischemia in the nonhuman primate. ILAR J. 44(2), 96-104 (2003). (Pubitemid 36410963)
-
(2003)
ILAR Journal
, vol.44
, Issue.2
, pp. 96-104
-
-
Fukuda, S.1
Del Zoppo, G.J.2
-
70
-
-
76349121799
-
Permanent or transient chronic ischemic stroke in the non-human primate: Behavioral, neuroimaging, histological, and immunohistochemical investigations
-
Bihel E, Pro-Sistiaga P, Letourneur A et al. Permanent or transient chronic ischemic stroke in the non-human primate: behavioral, neuroimaging, histological, and immunohistochemical investigations. J. Cereb. Blood Flow Metab. 30(2), 273-285 (2010).
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, Issue.2
, pp. 273-285
-
-
Bihel, E.1
Pro-Sistiaga, P.2
Letourneur, A.3
-
71
-
-
0022483434
-
Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
-
Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17(3), 472-476 (1986). (Pubitemid 16085691)
-
(1986)
Stroke
, vol.17
, Issue.3
, pp. 472-476
-
-
Bederson, J.B.1
Pitts, L.H.2
Tsuji, M.3
-
72
-
-
0024494427
-
Reversible middle cerebral artery occlusion without craniectomy in rats
-
Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20(1), 84-91 (1989). (Pubitemid 19040218)
-
(1989)
Stroke
, vol.20
, Issue.1
, pp. 84-91
-
-
Longa, E.Z.1
Weinstein, P.R.2
Carlson, S.3
Cummins, R.4
-
73
-
-
0041695258
-
Evaluation of MCAO stroke models in normotensive rats: Standardized neocortical infarction by the 3VO technique
-
DOI 10.1016/S0014-4886(03)00116-X
-
Yanamoto H, Nagata I, Niitsu Y, Xue JH, Zhang Z, Kikuchi H. Evaluation of MCAO stroke models in normotensive rats: standardized neocortical infarction by the 3VO technique. Exp. Neurol. 182(2), 261-274 (2003). (Pubitemid 36937080)
-
(2003)
Experimental Neurology
, vol.182
, Issue.2
, pp. 261-274
-
-
Yanamoto, H.1
Nagata, I.2
Niitsu, Y.3
Xue, J.-H.4
Zhang, Z.5
Kikuchi, H.6
-
74
-
-
0035701822
-
Rat middle cerebral artery occlusion: Correlations between histopathology, T2-weighted magnetic resonance imaging, and behavioral indices
-
DOI 10.1053/jscd.2001.26865
-
Peeling J, Corbett D, Del Bigio MR, Hudzik TJ, Campbell TM, Palmer GC. Rat middle cerebral artery occlusion: correlations between histopathology, T2-weighted magnetic resonance imaging, and behavioral indices. J. Stroke Cerebrovasc. Dis. 10(4), 166-177 (2001). (Pubitemid 34098126)
-
(2001)
Journal of Stroke and Cerebrovascular Diseases
, vol.10
, Issue.4
, pp. 166-177
-
-
Peeling, J.1
Corbett, D.2
Del Bigio, M.R.3
Hudzik, T.J.4
Campbell, T.M.5
Palmer, G.C.6
-
75
-
-
0034743293
-
2-weighted MRI correlates with long-term histopathology, neurology scores, and skilled motor behavior in a rat stroke model
-
Palmer GC, Peeling J, Corbett D, Del Bigio MR, Hudzik TJ. T2-weighted MRI correlates with long-term histopathology, neurology scores, and skilled motor behavior in a rat stroke model. Ann. NY Acad. Sci. 939, 283-296 (2001). (Pubitemid 32620078)
-
(2001)
Annals of the New York Academy of Sciences
, vol.939
, pp. 283-296
-
-
Palmer, G.C.1
Peeling, J.2
Corbett, D.3
Del Bigio, M.R.4
Hudzik, T.J.5
-
76
-
-
0032961564
-
Infarct volume as a surrogate or auxiliary outcome measure in ischemic stroke clinical trials
-
Saver JL, Johnston KC, Homer D et al. Infarct volume as a surrogate or auxiliary outcome measure in ischemic stroke clinical trials. The RANTTAS Investigators. Stroke 30(2), 293-298 (1999). (Pubitemid 29071792)
-
(1999)
Stroke
, vol.30
, Issue.2
, pp. 293-298
-
-
Saver, J.L.1
Johnston, K.C.2
Homer, D.3
Wityk, R.4
Koroshetz, W.5
Truskowski, L.L.6
Haley, E.C.7
-
78
-
-
0034933608
-
Cognitive and behavioral assessment in experimental stroke research: Will it prove useful?
-
DOI 10.1016/S0149-7634(01)00017-3, PII S0149763401000173
-
Devries AC, Nelson RJ, Traystman RJ, Hurn PD. Cognitive and behavioral assessment in experimental stroke research: will it prove useful? Neurosci. Biobehav. Rev. 25(4), 325-342 (2001). (Pubitemid 32624375)
-
(2001)
Neuroscience and Biobehavioral Reviews
, vol.25
, Issue.4
, pp. 325-342
-
-
DeVries, A.C.1
Nelson, R.J.2
Traystman, R.J.3
Hurn, P.D.4
-
79
-
-
0027315232
-
Paw-reaching, sensorimotor, and rotational behavior after brain infarction in rats
-
Grabowski M, Brundin P, Johansson BB. Paw-reaching, sensorimotor, and rotational behavior after brain infarction in rats. Stroke 24(6), 889-895 (1993). (Pubitemid 23163564)
-
(1993)
Stroke
, vol.24
, Issue.6
, pp. 889-895
-
-
Grabowski, M.1
Brundin, P.2
Johansson, B.B.3
Kontos, H.A.4
-
80
-
-
0035168782
-
A comparison of long-term functional outcome after 2 middle cerebral artery occlusion models in rats
-
Roof RL, Schielke GP, Ren X, Hall ED. A comparison of long-term functional outcome after 2 middle cerebral artery occlusion models in rats. Stroke 32(11), 2648-2657 (2001). (Pubitemid 33055320)
-
(2001)
Stroke
, vol.32
, Issue.11
, pp. 2648-2657
-
-
Roof, R.L.1
Schielke, G.P.2
Ren, X.3
Hall, E.D.4
-
81
-
-
19544376511
-
Neuroprotection for Ischemic Stroke: Two Decades of Success and Failure
-
DOI 10.1602/neurorx.1.1.36, PII S1545534306700062
-
Cheng YD, Al-Khoury L, Zivin JA. Neuroprotection for ischemic stroke: two decades of success and failure. NeuroRx 1(1), 36-45 (2004). (Pubitemid 46589340)
-
(2004)
NeuroRx
, vol.1
, Issue.1
, pp. 36-45
-
-
Cheng, Y.D.1
Al-Khoury, L.2
Zivin, J.A.3
-
82
-
-
0024805137
-
Rodent models of cerebral ischemia
-
Ginsberg MD, Busto R. Rodent models of cerebral ischemia. Stroke 20(12), 1627-1642 (1989). (Pubitemid 20030870)
-
(1989)
Stroke
, vol.20
, Issue.12
, pp. 1627-1642
-
-
Ginsberg, M.D.1
Busto, R.2
-
83
-
-
0033972303
-
Temperature modulation (hypothermic and hyperthermic conditions) and its influence on histological and behavioral outcomes following cerebral ischemia
-
Corbett D, Thornhill J. Temperature modulation (hypothermic and hyperthermic conditions) and its influence on histological and behavioral outcomes following cerebral ischemia. Brain Pathol. 10(1), 145-152 (2000). (Pubitemid 30056402)
-
(2000)
Brain Pathology
, vol.10
, Issue.1
, pp. 145-152
-
-
Corbett, D.1
Thornhill, J.2
-
84
-
-
0025012714
-
Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia
-
Buchan A, Pulsinelli WA. Hypothermia but not the N-methyl-d-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia. J. Neurosci. 10(1), 311-316 (1990). (Pubitemid 20059267)
-
(1990)
Journal of Neuroscience
, vol.10
, Issue.1
, pp. 311-316
-
-
Buchan, A.1
Pulsinelli, W.A.2
-
85
-
-
56649103770
-
Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review
-
Hainsworth AH, Markus HS. Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review. J. Cereb. Blood Flow Metab. 28(12), 1877-1891 (2008).
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, Issue.12
, pp. 1877-1891
-
-
Hainsworth, A.H.1
Markus, H.S.2
-
86
-
-
37549068172
-
Missing steps in the STAIR case: A translational medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke
-
Feuerstein GZ, Zaleska MM, Krams M et al. Missing steps in the STAIR case: a translational medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke. J. Cereb. Blood Flow Metab. 28(1), 217-219 (2008).
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, Issue.1
, pp. 217-219
-
-
Feuerstein, G.Z.1
Zaleska, M.M.2
Krams, M.3
-
87
-
-
77956267967
-
Methodological quality of preclinical stroke studies is not required for publication in high-impact journals
-
Minnerup J, Wersching H, Diederich K et al. Methodological quality of preclinical stroke studies is not required for publication in high-impact journals. J. Cereb. Blood Flow Metab. 30(9), 1619-1624 (2010).
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, Issue.9
, pp. 1619-1624
-
-
Minnerup, J.1
Wersching, H.2
Diederich, K.3
-
88
-
-
9244232873
-
Primate phylogeny: Molecular evidence from retroposons
-
DOI 10.1159/000080799
-
Schmitz J, Roos C, Zischler H. Primate phylogeny: molecular evidence from retroposons. Cytogenet. Genome Res. 108(1-3), 26-37 (2005). (Pubitemid 39551765)
-
(2005)
Cytogenetic and Genome Research
, vol.108
, Issue.1-3
, pp. 26-37
-
-
Schmitz, J.1
Roos, C.2
Zischler, H.3
-
89
-
-
58549088982
-
The development of stroke therapeutics: Promising mechanisms and translational challenges
-
Zaleska MM, Mercado ML, Chavez J, Feuerstein GZ, Pangalos MN, Wood A. The development of stroke therapeutics: promising mechanisms and translational challenges. Neuropharmacology 56(2), 329-341 (2009).
-
(2009)
Neuropharmacology
, vol.56
, Issue.2
, pp. 329-341
-
-
Zaleska, M.M.1
Mercado, M.L.2
Chavez, J.3
Feuerstein, G.Z.4
Pangalos, M.N.5
Wood, A.6
-
90
-
-
3042805396
-
Stroke in the female: Role of biological sex and estrogen
-
Murphy SJ, Mccullough LD, Smith JM. Stroke in the female: role of biological sex and estrogen. ILAR J. 45(2), 147-159 (2004).
-
(2004)
ILAR J.
, vol.45
, Issue.2
, pp. 147-159
-
-
Murphy, S.J.1
McCullough, L.D.2
Smith, J.M.3
-
91
-
-
9344246907
-
Animal models of ischemic stroke: Balancing experimental aims and animal care
-
Graham SM, Mccullough LD, Murphy SJ. Animal models of ischemic stroke: balancing experimental aims and animal care. Comp. Med. 54(5), 486-496 (2004). (Pubitemid 39557442)
-
(2004)
Comparative Medicine
, vol.54
, Issue.5
, pp. 486-496
-
-
Graham, S.M.1
McCullough, L.D.2
Murphy, S.J.3
-
93
-
-
0020656735
-
Acute NMR changes during MCA occlusion: A preliminary study in primates
-
Spetzler RF, Zabramski JM, Kaufman B, Yeung HN. Acute NMR changes during MCA occlusion: a preliminary study in primates. Stroke 14(2), 185-191 (1983). (Pubitemid 13159735)
-
(1983)
Stroke
, vol.14
, Issue.2
, pp. 185-191
-
-
Spetzler, R.F.1
Zabramski, J.M.2
Kaufman, B.3
Yeung, H.N.4
-
94
-
-
10744229657
-
Serial magnetic resonance imaging in experimental primate stroke: Validation of MRI for pre-clinical cerebroprotective trials
-
DOI 10.1179/016164103771953943
-
Mack WJ, Komotar RJ, Mocco J et al. Serial magnetic resonance imaging in experimental primate stroke: validation of MRI for pre-clinical cerebroprotective trials. Neurol. Res. 25(8), 846-852 (2003). (Pubitemid 37499720)
-
(2003)
Neurological Research
, vol.25
, Issue.8
, pp. 846-852
-
-
Mack, W.J.1
Komotar, R.J.2
Mocco, J.3
Coon, A.L.4
Hoh, D.J.5
King, R.G.6
Ducruet, A.F.7
Ransom, E.R.8
Oppermann, M.9
DeLaPaz, R.10
Connolly Jr., E.S.11
-
95
-
-
0033667394
-
A modified transorbital baboon model of reperfused stroke
-
Huang J, Mocco J, Choudhri TF et al. A modified transorbital baboon model of reperfused stroke. Stroke 31(12), 3054-3063 (2000).
-
(2000)
Stroke
, vol.31
, Issue.12
, pp. 3054-3063
-
-
Huang, J.1
Mocco, J.2
Choudhri, T.F.3
-
96
-
-
2442711779
-
A modified transorbital baboon model of reperfused stroke
-
DOI 10.1016/S0076-6879(04)86002-6
-
D'ambrosio AL, Sughrue ME, Mocco J et al. A modified transorbital baboon model of reperfused stroke. Methods Enzymol. 386, 60-73 (2004). (Pubitemid 38657587)
-
(2004)
Methods in Enzymology
, vol.386
, pp. 60-73
-
-
D'Ambrosio, A.L.1
Sughrue, M.E.2
Mocco, J.3
Mack, W.J.4
King, R.G.5
Agarwal, S.6
Connolly Jr., E.S.7
-
97
-
-
0022871398
-
Experimental acute thrombotic stroke in baboons
-
Del Zoppo GJ, Copeland BR, Harker LA et al. Experimental acute thrombotic stroke in baboons. Stroke 17(6), 1254-1265 (1986). (Pubitemid 17008967)
-
(1986)
Stroke
, vol.17
, Issue.6
, pp. 1254-1265
-
-
Del Zoppo, G.J.1
Copeland, B.R.2
Harker, L.A.3
-
98
-
-
0037396349
-
An improved functional neurological examination for use in nonhuman primate studies of focal reperfused cerebral ischemia
-
DOI 10.1179/016164103101201346
-
Mack WJ, King RG, Hoh DJ et al. An improved functional neurological examination for use in nonhuman primate studies of focal reperfused cerebral ischemia. Neurol. Res. 25(3), 280-284 (2003). (Pubitemid 36520485)
-
(2003)
Neurological Research
, vol.25
, Issue.3
, pp. 280-284
-
-
Mack, W.J.1
King, R.G.2
Hoh, D.J.3
Coon, A.L.4
Ducruet, A.F.5
Huang, J.6
Mocco, J.7
Winfree, C.J.8
D'Ambrosio, A.L.9
Nair, M.N.10
Sciacca, R.R.11
Connolly Jr., E.S.12
-
99
-
-
0022530448
-
The beneficial effect of intracarotid urokinase on acute stroke in a baboon model
-
Del Zoppo GJ, Copeland BR, Waltz TA, Zyroff J, Plow EF, Harker LA. The beneficial effect of intracarotid urokinase on acute stroke in a baboon model. Stroke 17(4), 638-643 (1986). (Pubitemid 16066531)
-
(1986)
Stroke
, vol.17
, Issue.4
, pp. 638-643
-
-
Del Zoppo, G.J.1
Copeland, B.R.2
Waltz, T.A.3
-
100
-
-
26444510219
-
Extending reperfusion therapy for acute ischemic stroke: Emerging pharmacological, mechanical, and imaging strategies
-
DOI 10.1161/01.STR.0000182100.65262.46
-
Molina CA, Saver JL. Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke 36(10), 2311-2320 (2005). (Pubitemid 41429268)
-
(2005)
Stroke
, vol.36
, Issue.10
, pp. 2311-2320
-
-
Molina, C.A.1
Saver, J.L.2
-
101
-
-
33749527060
-
Preclinical evaluation of the neuroprotective effect of soluble complement receptor type 1 in a nonhuman primate model of reperfused stroke
-
Mocco J, Mack WJ, Ducruet AF et al. Preclinical evaluation of the neuroprotective effect of soluble complement receptor type 1 in a nonhuman primate model of reperfused stroke. J. Neurosurg. 105(4), 595-601 (2006). (Pubitemid 44525892)
-
(2006)
Journal of Neurosurgery
, vol.105
, Issue.4
, pp. 595-601
-
-
Mocco, J.1
Mack, W.J.2
Ducruet, A.F.3
King, R.G.4
Sughrue, M.E.5
Coon, A.L.6
Sosunov, S.A.7
Sciacca, R.R.8
Zhang, Y.9
Marsh Jr., H.C.10
Pinsky, D.J.11
Connolly Jr., E.S.12
-
102
-
-
35748936795
-
x-glycosylated complement inhibitory protein in a non-human primate model of reperfused stroke
-
DOI 10.1111/j.1600-0684.2007.00213.x
-
Ducruet AF, Mocco J, Mack WJ et al. Pre-clinical evaluation of an sLe x-glycosylated complement inhibitory protein in a non-human primate model of reperfused stroke. J. Med. Primatol. 36(6), 375-380 (2007). (Pubitemid 350042175)
-
(2007)
Journal of Medical Primatology
, vol.36
, Issue.6
, pp. 375-380
-
-
Ducruet, A.F.1
Mocco, J.2
Mack, W.J.3
Coon, A.L.4
Marsh, H.C.5
Pinsky, D.J.6
Hickman, Z.L.7
Kim, G.H.8
Connolly Jr., E.S.9
-
103
-
-
0037112549
-
HuEP5C7 as a humanized monoclonal anti-E/P-selectin neurovascular protective strategy in a blinded placebo-controlled trial of nonhuman primate stroke
-
DOI 10.1161/01.RES.0000042063.15901.20
-
Mocco J, Choudhri T, Huang J et al. HuEP5C7 as a humanized monoclonal anti-E/P-selectin neurovascular protective strategy in a blinded placebo-controlled trial of nonhuman primate stroke. Circ. Res. 91(10), 907-914 (2002). (Pubitemid 35373590)
-
(2002)
Circulation Research
, vol.91
, Issue.10
, pp. 907-914
-
-
Mocco, J.1
Choudhri, T.2
Huang, J.3
Harfeldt, E.4
Efros, L.5
Klingbeil, C.6
Vexler, V.7
Hall, W.8
Zhang, Y.9
Mack, W.10
Popilskis, S.11
Pinsky, D.J.12
Connolly Jr., E.S.13
-
104
-
-
20044379398
-
Acute studies of a new primate model of reversible middle cerebral artery occlusion
-
DOI 10.1016/j.jstrokecerebrovasdis.2004.12.005
-
De Crespigny AJ, D'arceuil HE, Maynard KI et al. Acute studies of a new primate model of reversible middle cerebral artery occlusion. J. Stroke Cerebrovasc. Dis. 14(2), 80-87 (2005). (Pubitemid 40332498)
-
(2005)
Journal of Stroke and Cerebrovascular Diseases
, vol.14
, Issue.2
, pp. 80-87
-
-
De Crespigny, A.J.1
D'Arceuil, H.E.2
Maynard, K.I.3
He, J.4
McAuliffe, D.5
Norbash, A.6
Sehgal, P.K.7
Hamberg, L.8
Hunter, G.9
Budzik, R.F.10
Putman, C.M.11
Gonzalez, R.G.12
-
105
-
-
0037240633
-
Chronic ischemic stroke model in cynomolgus monkeys: Behavioral, neuroimaging and anatomical study
-
DOI 10.1179/016164103101200950
-
Roitberg B, Khan N, Tuccar E et al. Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study. Neurol. Res. 25(1), 68-78 (2003). (Pubitemid 36106053)
-
(2003)
Neurological Research
, vol.25
, Issue.1
, pp. 68-78
-
-
Roitberg, B.1
Khan, N.2
Tuccar, E.3
Kompoliti, K.4
Chu, Y.5
Alperin, N.6
Kordower, J.H.7
Emborg, M.E.8
-
106
-
-
59049100044
-
Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia?
-
Murphy SJ, Kirsch JR, Zhang W et al. Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia? Comp. Med. 58(6), 588-596 (2008).
-
(2008)
Comp. Med.
, vol.58
, Issue.6
, pp. 588-596
-
-
Murphy, S.J.1
Kirsch, J.R.2
Zhang, W.3
-
107
-
-
0033870514
-
Detection of reperfusion injury using PET in a monkey model of cerebral ischemia
-
Takamatsu H, Tsukada H, Kakiuchi T, Nishiyama S, Noda A, Umemura K. Detection of reperfusion injury using PET in a monkey model of cerebral ischemia. J. Nucl. Med. 41(8), 1409-1416 (2000). (Pubitemid 30643383)
-
(2000)
Journal of Nuclear Medicine
, vol.41
, Issue.8
, pp. 1409-1416
-
-
Takamatsu, H.1
Tsukada, H.2
Kakiuchi, T.3
Nishiyama, S.4
Noda, A.5
Umemura, K.6
-
109
-
-
34547659257
-
Neuroimaging and histopathological evaluation of delayed neurological damage produced by artificial occlusion of the middle cerebral artery in Cynomolgus monkeys. - Establishment of a monkey model for delayed cerebral ischemia
-
DOI 10.1016/j.etp.2007.02.008, PII S0940299307000139
-
Hirouchi Y, Suzuki E, Mitsuoka C et al. Neuroimaging and histopathological evaluation of delayed neurological damage produced by artificial occlusion of the middle cerebral artery in cynomolgus monkeys: establishment of a monkey model for delayed cerebral ischemia. Exp. Toxicol. Pathol. 59(1), 9-16 (2007). (Pubitemid 47223680)
-
(2007)
Experimental and Toxicologic Pathology
, vol.59
, Issue.1
, pp. 9-16
-
-
Hirouchi, Y.1
Suzuki, E.2
Mitsuoka, C.3
Jin, H.4
Kitajima, S.5
Kohjimoto, Y.6
Enomoto, M.7
Kugino, K.8
-
110
-
-
20144374304
-
Characterization of a novel thrombotic middle cerebral artery occlusion model in monkeys that exhibits progressive hypoperfusion and robust cortical infarction
-
DOI 10.1016/j.jneumeth.2005.01.019, PII S0165027005000452
-
Maeda M, Takamatsu H, Furuichi Y et al. Characterization of a novel thrombotic middle cerebral artery occlusion model in monkeys that exhibits progressive hypoperfusion and robust cortical infarction. J. Neurosci. Methods 146(1), 106-115 (2005). (Pubitemid 40776130)
-
(2005)
Journal of Neuroscience Methods
, vol.146
, Issue.1
, pp. 106-115
-
-
Maeda, M.1
Takamatsu, H.2
Furuichi, Y.3
Noda, A.4
Awaga, Y.5
Tatsumi, M.6
Yamamoto, M.7
Ichise, R.8
Nishimura, S.9
Matsuoka, N.10
-
111
-
-
33645861944
-
Effects of intra-arterial urokinase on a non-human primate thromboembolic stroke model
-
Susumu T, Yoshikawa T, Akiyoshi Y, Nagata R, Fujiwara M, Kito G. Effects of intra-arterial urokinase on a non-human primate thromboembolic stroke model. J. Pharmacol. Sci. 100(4), 278-284 (2006).
-
(2006)
J. Pharmacol. Sci.
, vol.100
, Issue.4
, pp. 278-284
-
-
Susumu, T.1
Yoshikawa, T.2
Akiyoshi, Y.3
Nagata, R.4
Fujiwara, M.5
Kito, G.6
-
112
-
-
0037424434
-
Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: Dose dependency, therapeutic time window and long-term efficacy
-
DOI 10.1016/S0006-8993(02)04151-3
-
Furuichi Y, Katsuta K, Maeda M et al. Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy. Brain Res. 965(1-2), 137-145 (2003). (Pubitemid 36183695)
-
(2003)
Brain Research
, vol.965
, Issue.1-2
, pp. 137-145
-
-
Furuichi, Y.1
Katsuta, K.2
Maeda, M.3
Ueyama, N.4
Moriguchi, A.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
113
-
-
33847360523
-
Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: Comparison with tissue plasminogen activator
-
DOI 10.1016/j.expneurol.2006.10.003, PII S0014488606005887
-
Furuichi Y, Maeda M, Matsuoka N, Mutoh S, Yanagihara T. Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator. Exp. Neurol. 204(1), 138-146 (2007). (Pubitemid 46335903)
-
(2007)
Experimental Neurology
, vol.204
, Issue.1
, pp. 138-146
-
-
Furuichi, Y.1
Maeda, M.2
Matsuoka, N.3
Mutoh, S.4
Yanagihara, T.5
-
114
-
-
0035662825
-
FK506 attenuates early ischemic neuronal death in a monkey model of stroke
-
Takamatsu H, Tsukada H, Noda A et al. FK506 attenuates early ischemic neuronal death in a monkey model of stroke. J. Nucl. Med. 42(12), 1833-1840 (2001). (Pubitemid 34016354)
-
(2001)
Journal of Nuclear Medicine
, vol.42
, Issue.12
, pp. 1833-1840
-
-
Takamatsu, H.1
Tsukada, H.2
Noda, A.3
Kakiuchi, T.4
Nishiyama, S.5
Nishimura, S.6
Umemura, K.7
-
115
-
-
44349164016
-
1 reduces neurodegeneration in the peri-infarct area of a thromboembolic stroke model in non-human primates
-
DOI 10.1254/jphs.FP0071297
-
Yoshikawa T, Akiyoshi Y, Susumu T et al. Ginsenoside Rb1 reduces neurodegeneration in the peri-infarct area of a thromboembolic stroke model in non-human primates. J. Pharmacol. Sci. 107(1), 32-40 (2008). (Pubitemid 351744082)
-
(2008)
Journal of Pharmacological Sciences
, vol.107
, Issue.1
, pp. 32-40
-
-
Yoshikawa, T.1
Akiyoshi, Y.2
Susumu, T.3
Tokado, H.4
Fukuzaki, K.5
Nagata, R.6
Samukawa, K.7
Iwao, H.8
Kito, G.9
-
116
-
-
77956168352
-
Seroprevalence of Toxoplasma gondii in bred cynomolgus monkeys (Macaca fascicularis) in China
-
Li HL, Yan C, Li J et al. Seroprevalence of Toxoplasma gondii in bred cynomolgus monkeys (Macaca fascicularis) in China. J. Parasitol. 96(4), 807-808 (2010).
-
(2010)
J. Parasitol.
, vol.96
, Issue.4
, pp. 807-808
-
-
Li, H.L.1
Yan, C.2
Li, J.3
-
117
-
-
76749110723
-
Liposome-encapsulated hemoglobin ameliorates ischemic stroke in nonhuman primates: An acute study
-
Kawaguchi AT, Haida M, Yamano M, Fukumoto D, Ogata Y, Tsukada H. Liposome-encapsulated hemoglobin ameliorates ischemic stroke in nonhuman primates: an acute study. J. Pharmacol. Exp. Ther. 332(2), 429-436 (2010).
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, Issue.2
, pp. 429-436
-
-
Kawaguchi, A.T.1
Haida, M.2
Yamano, M.3
Fukumoto, D.4
Ogata, Y.5
Tsukada, H.6
-
118
-
-
33845978362
-
Translational research: Moving discovery to practice
-
DOI 10.1038/sj.clpt.6100029, PII 6100029
-
Zerhouni EA. Translational research: moving discovery to practice. Clin. Pharmacol. Ther. 81(1), 126-128 (2007). (Pubitemid 46050877)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.1
, pp. 126-128
-
-
Zerhouni, E.A.1
-
119
-
-
38049096095
-
The meaning of translational research and why it matters
-
Woolf SH. The meaning of translational research and why it matters. JAMA 299(2), 211-213 (2008).
-
(2008)
JAMA
, vol.299
, Issue.2
, pp. 211-213
-
-
Woolf, S.H.1
-
120
-
-
77950292456
-
A matching algorithm to address imbalances in study populations: Application to the National Institute of Neurological Diseases and Stroke Recombinant Tissue Plasminogen Activator Acute Stroke Trial
-
Mandava P, Kalkonde YV, Rochat RH, Kent TA. A matching algorithm to address imbalances in study populations: application to the National Institute of Neurological Diseases and Stroke Recombinant Tissue Plasminogen Activator Acute Stroke Trial. Stroke 41(4), 765-770 (2010).
-
(2010)
Stroke
, vol.41
, Issue.4
, pp. 765-770
-
-
Mandava, P.1
Kalkonde, Y.V.2
Rochat, R.H.3
Kent, T.A.4
-
121
-
-
24644483617
-
Optimizing cutoff scores for the Barthel Index and the modified Rankin Scale for defining outcome in acute stroke trials
-
DOI 10.1161/01.STR.0000177872.87960.61
-
Uyttenboogaart M, Stewart RE, Vroomen PC, De Keyser J, Luijckx GJ. Optimizing cutoff scores for the Barthel index and the modified Rankin scale for defining outcome in acute stroke trials. Stroke 36(9), 1984-1987 (2005). (Pubitemid 41266538)
-
(2005)
Stroke
, vol.36
, Issue.9
, pp. 1984-1987
-
-
Uyttenboogaart, M.1
Stewart, R.E.2
Vroomen, P.C.A.J.3
De Keyser, J.4
Luijckx, G.-J.5
-
122
-
-
0036281510
-
Heterogeneity of stroke pathophysiology and neuroprotective clinical trial design
-
DOI 10.1161/01.STR.0000018684.86293.AB
-
Muir KW. Heterogeneity of stroke pathophysiology and neuroprotective clinical trial design. Stroke 33(6), 1545-1550 (2002). (Pubitemid 34619955)
-
(2002)
Stroke
, vol.33
, Issue.6
, pp. 1545-1550
-
-
Muir, K.W.1
-
123
-
-
41249090758
-
Empirical evidence of bias in the design of experimental stroke studies: A metaepidemiologic approach
-
DOI 10.1161/STROKEAHA.107.498725
-
Crossley NA, Sena E, Goehler J et al. Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach. Stroke 39(3), 929-934 (2008). (Pubitemid 351619572)
-
(2008)
Stroke
, vol.39
, Issue.3
, pp. 929-934
-
-
Crossley, N.A.1
Sena, E.2
Goehler, J.3
Horn, J.4
Van Der Worp, B.5
Bath, P.M.W.6
MacLeod, M.7
Dirnagl, U.8
-
124
-
-
0033019138
-
What are surrogate outcome measures and why do they fail in clinical research?
-
DOI 10.1159/000026208
-
Johnston K. What are surrogate outcome measures and why do they fail in clinical research? Neuroepidemiology 18(4), 167-173 (1999). (Pubitemid 29284077)
-
(1999)
Neuroepidemiology
, vol.18
, Issue.4
, pp. 167-173
-
-
Johnston, K.C.1
-
125
-
-
0028803360
-
Changes of relaxation times (T1, T2) and apparent diffusion coefficient after permanent middle cerebral artery occlusion in the rat: Temporal evolution, regional extent, and comparison with histology
-
Hoehn-Berlage M, Eis M, Back T, Kohno K, Yamashita K. Changes of relaxation times (T1, T2) and apparent diffusion coefficient after permanent middle cerebral artery occlusion in the rat: temporal evolution, regional extent, and comparison with histology. Magn. Reson. Med. 34(6), 824-834 (1995).
-
(1995)
Magn. Reson. Med.
, vol.34
, Issue.6
, pp. 824-834
-
-
Hoehn-Berlage, M.1
Eis, M.2
Back, T.3
Kohno, K.4
Yamashita, K.5
-
126
-
-
76349085893
-
Correlating tissue outcome with quantitative multiparametric MRI of acute cerebral ischemia in rats
-
Jokivarsi KT, Hiltunen Y, Tuunanen PI, Kauppinen RA, Grohn OH. Correlating tissue outcome with quantitative multiparametric MRI of acute cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 30(2), 415-427 (2010).
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, Issue.2
, pp. 415-427
-
-
Jokivarsi, K.T.1
Hiltunen, Y.2
Tuunanen, P.I.3
Kauppinen, R.A.4
Grohn, O.H.5
-
127
-
-
0022870943
-
Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats
-
Bederson JB, Pitts LH, Germano SM, Nishimura MC, Davis RL, Bartkowski HM. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17(6), 1304-1308 (1986). (Pubitemid 17008976)
-
(1986)
Stroke
, vol.17
, Issue.6
, pp. 1304-1308
-
-
Bederson, J.B.1
Pitts, L.H.2
Germano, S.M.3
-
128
-
-
16544375117
-
Pharmacokinetic animal PET study of FK506 as a potent neuroprotective agent
-
Murakami Y, Takamatsu H, Noda A et al. Pharmacokinetic animal PET study of FK506 as a potent neuroprotective agent. J. Nucl. Med. 45(11), 1946-1949 (2004). (Pubitemid 47618455)
-
(2004)
Journal of Nuclear Medicine
, vol.45
, Issue.11
, pp. 1946-1949
-
-
Murakami, Y.1
Takamatsu, H.2
Noda, A.3
Osoda, K.4
Ichise, R.5
Tatsumi, M.6
Tabata, K.7
Sawamoto, T.8
Nishimura, S.9
-
129
-
-
0018114449
-
Experimental stroke in gerbils: Effect on translation and transcription
-
DOI 10.1016/0006-8993(78)90686-8
-
Yanagihara T. Experimental stroke in gerbils: effect on translation and transcription. Brain Res. 158(2), 435-444 (1978). (Pubitemid 9040957)
-
(1978)
Brain Research
, vol.158
, Issue.2
, pp. 435-444
-
-
Yanagihara, T.1
-
130
-
-
68249113718
-
MAP2 immunostaining in thick sections for early ischemic stroke infarct volume in non-human primate brain
-
Kharlamov A, Laverde GC, Nemoto EM et al. MAP2 immunostaining in thick sections for early ischemic stroke infarct volume in non-human primate brain. J. Neurosci. Methods 182(2), 205-210 (2009).
-
(2009)
J. Neurosci. Methods
, vol.182
, Issue.2
, pp. 205-210
-
-
Kharlamov, A.1
Laverde, G.C.2
Nemoto, E.M.3
-
131
-
-
0019822988
-
Thresholds in cerebral ischemia - The ischemic penumbra
-
Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia - the ischemic penumbra. Stroke 12(6), 723-725 (1981). (Pubitemid 12227362)
-
(1981)
Stroke
, vol.12
, Issue.6
, pp. 723-725
-
-
Astrup, J.1
Siejo, B.K.2
Symon, L.3
-
132
-
-
2442691625
-
A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. II. Volume of distribution and mean residence time
-
DOI 10.1124/dmd.32.6.612
-
Ward KW, Smith BR. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. II. Volume of distribution and mean residence time. Drug Metab. Dispos. 32(6), 612-619 (2004). (Pubitemid 38668153)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.6
, pp. 612-619
-
-
Ward, K.W.1
Smith, B.R.2
-
133
-
-
0037250575
-
A squirrel monkey model of poststroke motor recovery
-
Nudo RJ, Larson D, Plautz EJ, Friel KM, Barbay S, Frost SB. A squirrel monkey model of poststroke motor recovery. ILAR J. 44(2), 161-174 (2003). (Pubitemid 36410970)
-
(2003)
ILAR Journal
, vol.44
, Issue.2
, pp. 161-174
-
-
Nudo, R.J.1
Larson, D.2
Plautz, E.J.3
Friel, K.M.4
Barbay, S.5
Frost, S.B.6
-
134
-
-
0019507004
-
Selective lenticulostriate occlusion in the primate. A highly focal cerebral ischemia model
-
Yonas H, Wolfson SK Jr, Dujovny M, Boehnke M, Cook E. Selective lenticulostriate occlusion in the primate. A highly focal cerebral ischemia model. Stroke 12(5), 567-572 (1981). (Pubitemid 11030058)
-
(1981)
Stroke
, vol.12
, Issue.5
, pp. 567-572
-
-
Yonas, H.1
Wolfson Jr., S.D.2
Dujovny, M.3
-
135
-
-
0036087814
-
Functional CT perfusion imaging in predicting the extent of cerebral infarction from a 3-hour middle cerebral arterial occlusion in a primate stroke model
-
Hamberg LM, Hunter GJ, Maynard KI et al. Functional CT perfusion imaging in predicting the extent of cerebral infarction from a 3-hour middle cerebral arterial occlusion in a primate stroke model. AJNR Am. J. Neuroradiol. 23(6), 1013-1021 (2002). (Pubitemid 34663450)
-
(2002)
American Journal of Neuroradiology
, vol.23
, Issue.6
, pp. 1013-1021
-
-
Hamberg, L.M.1
Hunter, G.J.2
Maynard, K.I.3
Owen, C.4
Morris, P.P.5
Putman, C.M.6
Ogilvy, C.7
Gonzalez, R.G.8
-
136
-
-
33644804061
-
Middle cerebral artery occlusion in Macaca fascicularis: Acute and chronic stroke evolution
-
DOI 10.1111/j.1600-0684.2006.00147.x
-
D'arceuil HE, Duggan M, He J, Pryor J, De Crespigny A. Middle cerebral artery occlusion in Macaca fascicularis: acute and chronic stroke evolution. J. Med. Primatol. 35(2), 78-86 (2006). (Pubitemid 43349101)
-
(2006)
Journal of Medical Primatology
, vol.35
, Issue.2
, pp. 78-86
-
-
D'Arceuil, H.E.1
Duggan, M.2
He, J.3
Pryor, J.4
De Crespigny, A.5
-
137
-
-
0035970047
-
Experimental thromboembolic stroke in cynomolgus monkey
-
DOI 10.1016/S0165-0270(00)00351-4, PII S0165027000003514
-
Kito G, Nishimura A, Susumu T et al. Experimental thromboembolic stroke in cynomolgus monkey. J. Neurosci. Methods 105(1), 45-53 (2001). (Pubitemid 32109224)
-
(2001)
Journal of Neuroscience Methods
, vol.105
, Issue.1
, pp. 45-53
-
-
Kito, G.1
Nishimura, A.2
Susumu, T.3
Nagata, R.4
Kuge, Y.5
Yokota, C.6
Minematsu, K.7
-
138
-
-
0035092908
-
Serial changes in cerebral blood flow and flow-metabolism uncoupling in primates with acute thromboembolic stroke
-
Kuge Y, Yokota C, Tagaya M et al. Serial changes in cerebral blood flow and flow-metabolism uncoupling in primates with acute thromboembolic stroke. J. Cereb. Blood Flow Metab. 21(3), 202-210 (2001). (Pubitemid 32207419)
-
(2001)
Journal of Cerebral Blood Flow and Metabolism
, vol.21
, Issue.3
, pp. 202-210
-
-
Kuge, Y.1
Yokota, C.2
Tagaya, M.3
Hasegawa, Y.4
Nishimura, A.5
Kito, G.6
Tamaki, N.7
Hashimoto, N.8
Yamaguchi, T.9
Minematsu, K.10
-
139
-
-
28144439355
-
Intraarterial reteplase and intravenous abciximab for treatment of acute ischemic stroke. A preliminary feasibility and safety study in a non-human primate model
-
DOI 10.1007/s00234-003-1097-7
-
Qureshi AI, Suri MF, Ali Z et al. Intraarterial reteplase and intravenous abciximab for treatment of acute ischemic stroke. A preliminary feasibility and safety study in a non-human primate model. Neuroradiology 47(11), 845-854 (2005). (Pubitemid 41693208)
-
(2005)
Neuroradiology
, vol.47
, Issue.11
, pp. 845-854
-
-
Qureshi, A.I.1
Suri, M.F.K.2
Ali, Z.3
Ringer, A.J.4
Boulos, A.S.5
Nakada, M.T.6
Alberico, R.A.7
Martin, L.B.E.8
Guterman, L.R.9
Hopkins, L.N.10
-
140
-
-
66949153247
-
Bioethical considerations in translational research: Primate stroke
-
Sughrue ME, Mocco J, Mack WJ et al. Bioethical considerations in translational research: primate stroke. Am. J. Bioeth. 9(5), 3-12 (2009).
-
(2009)
Am. J. Bioeth.
, vol.9
, Issue.5
, pp. 3-12
-
-
Sughrue, M.E.1
Mocco, J.2
MacK, W.J.3
-
141
-
-
0029815102
-
Considerations in the design of clinical trials of neuroprotective therapy in acute stroke
-
Dorman PJ, Sandercock PA. Considerations in the design of clinical trials of neuroprotective therapy in acute stroke. Stroke 27(9), 1507-1515 (1996). (Pubitemid 26295897)
-
(1996)
Stroke
, vol.27
, Issue.9
, pp. 1507-1515
-
-
Dorman, P.J.1
Sandercock, P.A.G.2
-
142
-
-
0015544566
-
Unit activity in prefrontal cortex during delayed-response performance: Neuronal correlates of transient memory
-
Fuster JM. Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory. J. Neurophysiol. 36(1), 61-78 (1973).
-
(1973)
J. Neurophysiol.
, vol.36
, Issue.1
, pp. 61-78
-
-
Fuster, J.M.1
-
143
-
-
0021349076
-
Preserved learning in monkeys with medial temporal lesions: Sparing of motor and cognitive skills
-
Zola-Morgan S, Squire LR. Preserved learning in monkeys with medial temporal lesions: sparing of motor and cognitive skills. J. Neurosci. 4(4), 1072-1085 (1984). (Pubitemid 14146836)
-
(1984)
Journal of Neuroscience
, vol.4
, Issue.4
, pp. 1072-1085
-
-
Zola-Morgan, S.1
Squire, L.R.2
-
144
-
-
0031902287
-
Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease
-
DOI 10.1038/nm0898-963
-
Palfi S, Conde F, Riche D et al. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease. Nat. Med. 4(8), 963-966 (1998). (Pubitemid 28364039)
-
(1998)
Nature Medicine
, vol.4
, Issue.8
, pp. 963-966
-
-
Palfi, S.1
Conde, F.2
Riche, D.3
Brouillet, E.4
Dautry, C.5
Mittoux, V.6
Chibois, A.7
Peschanski, M.8
Hantraye, P.9
-
145
-
-
0030765344
-
Patterns of cognitive decline in aged rhesus monkeys
-
DOI 10.1016/S0166-4328(96)02256-5, PII S0166432896022565
-
Herndon JG, Moss MB, Rosene DL, Killiany RJ. Patterns of cognitive decline in aged rhesus monkeys. Behav. Brain Res. 87(1), 25-34 (1997). (Pubitemid 27421546)
-
(1997)
Behavioural Brain Research
, vol.87
, Issue.1
, pp. 25-34
-
-
Herndon, J.G.1
Moss, M.B.2
Rosene, D.L.3
Killiany, R.J.4
-
146
-
-
0037216101
-
Impairment in abstraction and set shifting in aged Rhesus monkeys
-
DOI 10.1016/S0197-4580(02)00054-4, PII S0197458002000544
-
Moore TL, Killiany RJ, Herndon JG, Rosene DL, Moss MB. Impairment in abstraction and set shifting in aged rhesus monkeys. Neurobiol. Aging 24(1), 125-134 (2003). (Pubitemid 36001986)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.1
, pp. 125-134
-
-
Moore, T.L.1
Killiany, R.J.2
Herndon, J.G.3
Rosene, D.L.4
Moss, M.B.5
-
147
-
-
34147181656
-
Cerebrovascular disease and dementia: A primate model of hypertension and cognition
-
DOI 10.1016/j.jalz.2007.01.002, PII S1552526007000052
-
Moss MB, Jonak E. Cerebrovascular disease and dementia: a primate model of hypertension and cognition. Alzheimers Dement. 3(Suppl. 2), S6-S15 (2007). (Pubitemid 46554902)
-
(2007)
Alzheimer's and Dementia
, vol.3
, Issue.2 SUPPL.
-
-
Moss, M.B.1
Jonak, E.2
-
148
-
-
39349100371
-
Neuroprotection does not work!
-
DOI 10.1161/STROKEAHA.107.494799, PII 0000767020080200000060
-
Rother J. Neuroprotection does not work! Stroke 39(2), 523-524 (2008). (Pubitemid 351619490)
-
(2008)
Stroke
, vol.39
, Issue.2
, pp. 523-524
-
-
Rother, J.1
-
149
-
-
62449174377
-
Good laboratory practice: Preventing introduction of bias at the bench
-
Macleod MR, Fisher M, O'collins V et al. Good laboratory practice: preventing introduction of bias at the bench. Stroke 40(3), e50-e52 (2009).
-
(2009)
Stroke
, vol.40
, Issue.3
-
-
MacLeod, M.R.1
Fisher, M.2
O'Collins, V.3
-
150
-
-
69249121556
-
Acute stroke therapy with tissue plasminogen activator (tPA) since it was approved by the U.S. Food and Drug Administration (FDA)
-
Zivin JA. Acute stroke therapy with tissue plasminogen activator (tPA) since it was approved by the U.S. Food and Drug Administration (FDA). Ann. Neurol. 66(1), 6-10 (2009).
-
(2009)
Ann. Neurol.
, vol.66
, Issue.1
, pp. 6-10
-
-
Zivin, J.A.1
-
151
-
-
67650082771
-
Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: A metaanalysis
-
Lansberg MG, Bluhmki E, Thijs VN. Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis. Stroke 40(7), 2438-2441 (2009).
-
(2009)
Stroke
, vol.40
, Issue.7
, pp. 2438-2441
-
-
Lansberg, M.G.1
Bluhmki, E.2
Thijs, V.N.3
-
152
-
-
0016770896
-
Local cerebral blood flow and vascular reactivity in a chronic stable stroke in baboons
-
Symon L, Crockard HA, Dorsch NW, Branston NM, Juhasz J. Local cerebral blood flow and vascular reactivity in a chronic stable stroke in baboons. Stroke 6(5), 482-492 (1975).
-
(1975)
Stroke
, vol.6
, Issue.5
, pp. 482-492
-
-
Symon, L.1
Crockard, H.A.2
Dorsch, N.W.3
Branston, N.M.4
Juhasz, J.5
-
153
-
-
0017623724
-
Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia
-
Astrup J, Symon L, Branston NM, Lassen NA. Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia. Stroke 8(1), 51-57 (1977).
-
(1977)
Stroke
, vol.8
, Issue.1
, pp. 51-57
-
-
Astrup, J.1
Symon, L.2
Branston, N.M.3
Lassen, N.A.4
-
154
-
-
42549133526
-
Optimal definition for PWI/DWI mismatch in acute ischemic stroke patients
-
DOI 10.1038/sj.jcbfm.9600604, PII 9600604
-
Kakuda W, Lansberg MG, Thijs VN et al. Optimal definition for PWI/DWI mismatch in acute ischemic stroke patients. J. Cereb. Blood Flow Metab. 28(5), 887-891 (2008). (Pubitemid 351589640)
-
(2008)
Journal of Cerebral Blood Flow and Metabolism
, vol.28
, Issue.5
, pp. 887-891
-
-
Kakuda, W.1
Lansberg, M.G.2
Thijs, V.N.3
Kemp, S.M.4
Bammer, R.5
Wechsler, L.R.6
Moseley, M.E.7
Parks, M.P.8
Albers, G.W.9
-
155
-
-
49849098015
-
Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)
-
Olivot JM, Mlynash M, Thijs VN et al. Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE). Stroke 39(8), 2257-2263 (2008).
-
(2008)
Stroke
, vol.39
, Issue.8
, pp. 2257-2263
-
-
Olivot, J.M.1
Mlynash, M.2
Thijs, V.N.3
-
156
-
-
79451474059
-
EPITHET: Positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration
-
Nagakane Y, Christensen S, Brekenfeld C et al. EPITHET: positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration. Stroke 42(1), 59-64 (2010).
-
(2010)
Stroke
, vol.42
, Issue.1
, pp. 59-64
-
-
Nagakane, Y.1
Christensen, S.2
Brekenfeld, C.3
-
157
-
-
45449110595
-
Optimal Outcome Measures for Detecting Clinical Benefits of Early Reperfusion: Insights from the DEFUSE Study
-
DOI 10.1016/j.jstrokecerebrovasdis.2008.03.001, PII S1052305708000694
-
Kakuda W, Hamilton S, Thijs VN et al. Optimal outcome measures for detecting clinical benefits of early reperfusion: insights from the DEFUSE Study. J. Stroke Cerebrovasc. Dis. 17(4), 235-240 (2008). (Pubitemid 351853446)
-
(2008)
Journal of Stroke and Cerebrovascular Diseases
, vol.17
, Issue.4
, pp. 235-240
-
-
Kakuda, W.1
Hamilton, S.2
Thijs, V.N.3
Lansberg, M.G.4
Kemp, S.5
Skalabrin, E.6
Albers, G.W.7
-
158
-
-
0037319340
-
New light on white matter
-
DOI 10.1161/01.STR.0000054048.22626.B9
-
Goldberg MP, Ransom BR. New light on white matter. Stroke 34(2), 330-332 (2003). (Pubitemid 36206313)
-
(2003)
Stroke
, vol.34
, Issue.2
, pp. 330-332
-
-
Goldberg, M.P.1
Ransom, B.R.2
-
159
-
-
33646714427
-
Ischemic thresholds for gray and white matter: A diffusion and perfusion magnetic resonance study
-
DOI 10.1161/01.STR.0000217258.63925.6b, PII 0000767020060500000025
-
Arakawa S, Wright PM, Koga M et al. Ischemic thresholds for gray and white matter: a diffusion and perfusion magnetic resonance study. Stroke 37(5), 1211-1216 (2006). (Pubitemid 43731864)
-
(2006)
Stroke
, vol.37
, Issue.5
, pp. 1211-1216
-
-
Arakawa, S.1
Wright, P.M.2
Koga, M.3
Phan, T.G.4
Reutens, D.C.5
Lim, I.6
Gunawan, M.R.7
Mam, H.8
Perera, N.9
Ly, J.10
Zavala, J.11
Fitt, G.12
Donnan, G.A.13
-
160
-
-
1842483228
-
The rise and fall of NMDA antagonists for ischemic stroke
-
DOI 10.2174/1566524043479248
-
Hoyte L, Barber PA, Buchan AM, Hill MD. The rise and fall of NMDA antagonists for ischemic stroke. Curr. Mol. Med. 4(2), 131-136 (2004). (Pubitemid 38425910)
-
(2004)
Current Molecular Medicine
, vol.4
, Issue.2
, pp. 131-136
-
-
Hoyte, L.1
Barber, P.A.2
Buchan, A.M.3
Hill, M.D.4
-
161
-
-
26444539696
-
The existence and evolution of diffusion-perfusion mismatched tissue in white and gray matter after acute stroke
-
DOI 10.1161/01.STR.0000181066.23213.8f
-
Koga M, Reutens DC, Wright P et al. The existence and evolution of diffusion-perfusion mismatched tissue in white and gray matter after acute stroke. Stroke 36(10), 2132-2137 (2005). (Pubitemid 41429233)
-
(2005)
Stroke
, vol.36
, Issue.10
, pp. 2132-2137
-
-
Koga, M.1
Reutens, D.C.2
Wright, P.3
Phan, T.4
Markus, R.5
Pedreira, B.6
Fitt, G.7
Lim, I.8
Donnan, G.A.9
-
162
-
-
0033053635
-
Drug development for stroke: Importance of protecting cerebral white
-
DOI 10.1016/S0014-2999(99)00280-0, PII S0014299999002800
-
Dewar D, Yam P, Mcculloch J. Drug development for stroke: importance of protecting cerebral white matter. Eur. J. Pharmacol. 375(1-3), 41-50 (1999). (Pubitemid 29317591)
-
(1999)
European Journal of Pharmacology
, vol.375
, Issue.1-3
, pp. 41-50
-
-
Dewar, D.1
Yam, P.2
McCulloch, J.3
-
163
-
-
33644520285
-
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
-
DOI 10.1038/nature04474, PII N04474
-
Micu I, Jiang Q, Coderre E et al. NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 439(7079), 988-992 (2006). (Pubitemid 43292418)
-
(2006)
Nature
, vol.439
, Issue.7079
, pp. 988-992
-
-
Micu, I.1
Jiang, Q.2
Coderre, E.3
Ridsdale, A.4
Zhang, L.5
Woulfe, J.6
Yin, X.7
Trapp, B.D.8
McRory, J.E.9
Rehak, R.10
Zamponi, G.W.11
Wang, W.12
Stys, P.K.13
-
164
-
-
62649146471
-
Combination therapy with hypothermia for treatment of cerebral ischemia
-
Tang XN, Liu L, Yenari MA. Combination therapy with hypothermia for treatment of cerebral ischemia. J. Neurotrauma 26(3), 325-331 (2009).
-
(2009)
J. Neurotrauma
, vol.26
, Issue.3
, pp. 325-331
-
-
Tang, X.N.1
Liu, L.2
Yenari, M.A.3
-
165
-
-
0032876536
-
Combination drug therapy and mild hypothermia: A promising treatment strategy for reversible, focal cerebral ischemia
-
Schmid-Elsaesser R, Hungerhuber E, Zausinger S, Baethmann A, Reulen HJ. Combination drug therapy and mild hypothermia: a promising treatment strategy for reversible, focal cerebral ischemia. Stroke 30(9), 1891-1899 (1999). (Pubitemid 29411833)
-
(1999)
Stroke
, vol.30
, Issue.9
, pp. 1891-1899
-
-
Schmid-Elsaesser, R.1
Hungerhuber, E.2
Zausinger, S.3
Baethmann, A.4
Reulen, H.-J.5
-
166
-
-
0005711784
-
Combination treatment for acute ischemic stroke: A ray of hope?
-
Fagan SC, Bowes MP, Berri SA, Zivin JA. Combination treatment for acute ischemic stroke: a ray of hope? J. Stroke Cerebrovasc. Dis. 8(6), 359-367 (1999).
-
(1999)
J. Stroke Cerebrovasc. Dis.
, vol.8
, Issue.6
, pp. 359-367
-
-
Fagan, S.C.1
Bowes, M.P.2
Berri, S.A.3
Zivin, J.A.4
-
167
-
-
60949087646
-
Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: A pilot study of caffeinol and mild hypothermia
-
Martin-Schild S, Hallevi H, Shaltoni H et al. Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: a pilot study of caffeinol and mild hypothermia. J. Stroke Cerebrovasc. Dis. 18(2), 86-96 (2009).
-
(2009)
J. Stroke Cerebrovasc. Dis.
, vol.18
, Issue.2
, pp. 86-96
-
-
Martin-Schild, S.1
Hallevi, H.2
Shaltoni, H.3
|