The development of stroke therapeutics: Promising mechanisms and translational challenges

Neuropharmacology

Volumn 56, Issue 2, 2009, Pages 329-341

  Zaleska, Margaret M ^a   Mercado, Mary Lynn T ^a   Chavez, Juan ^a   Feuerstein, Giora Z ^a   Pangalos, Menelas N ^a   Wood, Andrew ^a  

^a PFIZER INC   (United States)

Author keywords

Drug development; Inflammation; Ischemia; Neuroimaging; Neuroprotection; Regeneration; Translational medicine

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE; 2,3 DIHYDRO 3,4 CYCLOPENTANO 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; 4 (4 FLUOROPHENYL) 2 METHYL 6 (5 PIPERIDINOPENTYLOXY)PYRIMIDINE; ABCIXIMAB; AEOL 10150; ALFIMEPRASE; ALTEPLASE; ANCROD; ARGATROBAN; ARIMOCLOMAL; ARUNDIC ACID; AX 200; BAY 387271; BRX 345; CAFEINOL; CITICOLINE; DESMOTEPLASE; DISUFENTON SODIUM; ETHYLENEGLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID BIS(2 OCTYLOXYETHYL) ESTER; FIBRINOLYTIC AGENT; GRANULOCYTE COLONY STIMULATING FACTOR; HF 0220; HF 0420; ILS 920; LUAA 24493; MICROPLASMIN; MK 0724; MRX 801; MSC 1; NA 1; NEU 2000; NTX 265; ONO 2231; PICLOZOTAN; PN 02; PYRIDOXAL 5 PHOSPHATE; SOLULIN; SUN N8075; TS 011; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AUTOPHAGY; BRAIN TISSUE; CAUSE OF DEATH; CELL DEATH; CELL INFILTRATION; CELL PROLIFERATION; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; DEVICE; DISABILITY; DRUG EFFICACY; HUMAN; IMAGING; INFLAMMATION; NEUROIMAGING; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; STROKE; SYNAPSE;

ANIMALS; CLINICAL TRIALS AS TOPIC; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; FIBRINOLYTIC AGENTS; HUMANS; STROKE;

EID: 58549088982     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.10.006     Document Type: Review

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