-
1
-
-
0037167558
-
Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator
-
Alexandrov A.V., and Grotta J.C. Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator. Neurology 59 (2002) 862-867
-
(2002)
Neurology
, vol.59
, pp. 862-867
-
-
Alexandrov, A.V.1
Grotta, J.C.2
-
2
-
-
0033512004
-
Inflammatory mediators and stroke: new opportunities for novel therapeutics
-
Barone F.C., and Feuerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 19 (1999) 819-834
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
3
-
-
0033019790
-
Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury
-
Bochelen D., Rudin M., and Sauter A. Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury. J. Pharmacol. Exp. Ther. 288 (1999) 653-659
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.288
, pp. 653-659
-
-
Bochelen, D.1
Rudin, M.2
Sauter, A.3
-
4
-
-
0031470554
-
Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin
-
Chen Z.L., and Strickland S. Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 91 (1997) 917-925
-
(1997)
Cell
, vol.91
, pp. 917-925
-
-
Chen, Z.L.1
Strickland, S.2
-
5
-
-
0025766358
-
Cerebral hemorrhagic risk of aspirin or heparin therapy with thrombolytic treatment in rabbits
-
Clark W.M., Madden K.P., Lyden P.D., and Zivin J.A. Cerebral hemorrhagic risk of aspirin or heparin therapy with thrombolytic treatment in rabbits. Stroke 22 (1991) 872-876
-
(1991)
Stroke
, vol.22
, pp. 872-876
-
-
Clark, W.M.1
Madden, K.P.2
Lyden, P.D.3
Zivin, J.A.4
-
6
-
-
0023134694
-
Photochemically induced cerebral infarction: I. Early microvascular alterations
-
Dietrich W.D., Watson B.D., Busto R., Ginsberg M.D., and Bethea J.R. Photochemically induced cerebral infarction: I. Early microvascular alterations. Acta Neuropathol. (Berl.) 72 (1987) 315-325
-
(1987)
Acta Neuropathol. (Berl.)
, vol.72
, pp. 315-325
-
-
Dietrich, W.D.1
Watson, B.D.2
Busto, R.3
Ginsberg, M.D.4
Bethea, J.R.5
-
7
-
-
0037424434
-
Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy
-
Furuichi Y., Katsuta K., Maeda M., Ueyama N., Moriguchi A., Matsuoka N., Goto T., and Yanagihara T. Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy. Brain Res. 965 (2003) 137-145
-
(2003)
Brain Res.
, vol.965
, pp. 137-145
-
-
Furuichi, Y.1
Katsuta, K.2
Maeda, M.3
Ueyama, N.4
Moriguchi, A.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
8
-
-
0141994812
-
Tacrolimus, a potential neuroprotective agent, ameliorates ischemic brain damage and neurologic deficits after focal cerebral ischemia in nonhuman primates
-
Furuichi Y., Maeda M., Moriguchi A., Sawamoto T., Kawamura A., Matsuoka N., Mutoh S., and Yanagihara T. Tacrolimus, a potential neuroprotective agent, ameliorates ischemic brain damage and neurologic deficits after focal cerebral ischemia in nonhuman primates. J. Cereb. Blood Flow Metab. 23 (2003) 1183-1194
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 1183-1194
-
-
Furuichi, Y.1
Maeda, M.2
Moriguchi, A.3
Sawamoto, T.4
Kawamura, A.5
Matsuoka, N.6
Mutoh, S.7
Yanagihara, T.8
-
9
-
-
2942729463
-
Multiple modes of action of tacrolimus (FK506) for neuroprotective action on ischemic damage after transient focal cerebral ischemia in rats
-
Furuichi Y., Noto T., Li J.Y., Oku T., Ishiye M., Moriguchi A., Aramori I., Matsuoka N., Mutoh S., and Yanagihara T. Multiple modes of action of tacrolimus (FK506) for neuroprotective action on ischemic damage after transient focal cerebral ischemia in rats. Brain Res. 1014 (2004) 120-130
-
(2004)
Brain Res.
, vol.1014
, pp. 120-130
-
-
Furuichi, Y.1
Noto, T.2
Li, J.Y.3
Oku, T.4
Ishiye, M.5
Moriguchi, A.6
Aramori, I.7
Matsuoka, N.8
Mutoh, S.9
Yanagihara, T.10
-
10
-
-
0032541845
-
Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators
-
Hacke W., Kaste M., Fieschi C., von Kummer R., Davalos A., Meier D., Larrue V., Bluhmki E., Davis S., Donnan G., Schneider D., Diez-Tejedor E., and Trouillas P. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators. Lancet 352 (1998) 1245-1251
-
(1998)
Lancet
, vol.352
, pp. 1245-1251
-
-
Hacke, W.1
Kaste, M.2
Fieschi, C.3
von Kummer, R.4
Davalos, A.5
Meier, D.6
Larrue, V.7
Bluhmki, E.8
Davis, S.9
Donnan, G.10
Schneider, D.11
Diez-Tejedor, E.12
Trouillas, P.13
-
11
-
-
0033135379
-
FK506 prevents stroke-induced generation of ceramide and apoptosis signaling
-
Herr I., Martin-Villalba A., Kurz E., Roncaioli P., Schenkel J., Cifone M.G., and Debatin K.M. FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. Brain Res. 826 (1999) 210-219
-
(1999)
Brain Res.
, vol.826
, pp. 210-219
-
-
Herr, I.1
Martin-Villalba, A.2
Kurz, E.3
Roncaioli, P.4
Schenkel, J.5
Cifone, M.G.6
Debatin, K.M.7
-
12
-
-
0028882207
-
Effect of argatroban on microthrombi formation and brain damage in the rat middle cerebral artery thrombosis model
-
Kawai H., Umemura K., and Nakashima M. Effect of argatroban on microthrombi formation and brain damage in the rat middle cerebral artery thrombosis model. Jpn. J. Pharmacol. 69 (1995) 143-148
-
(1995)
Jpn. J. Pharmacol.
, vol.69
, pp. 143-148
-
-
Kawai, H.1
Umemura, K.2
Nakashima, M.3
-
13
-
-
0021713150
-
In vitro fibrinolytic activity of recombinant tissue-type plasminogen activator in the plasma of various primate species
-
Lijnen H.R., Maraafino Jr. B.J., and Collen D. In vitro fibrinolytic activity of recombinant tissue-type plasminogen activator in the plasma of various primate species. Thromb. Haemost. 52 (1984) 308-310
-
(1984)
Thromb. Haemost.
, vol.52
, pp. 308-310
-
-
Lijnen, H.R.1
Maraafino Jr., B.J.2
Collen, D.3
-
14
-
-
0036791876
-
A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: increased neuroprotective efficacy and extended therapeutic time window
-
Maeda M., Furuichi Y., Ueyama N., Moriguchi A., Satoh N., Matsuoka N., Goto T., and Yanagihara T. A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: increased neuroprotective efficacy and extended therapeutic time window. J. Cereb. Blood Flow Metab. 22 (2002) 1205-1211
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 1205-1211
-
-
Maeda, M.1
Furuichi, Y.2
Ueyama, N.3
Moriguchi, A.4
Satoh, N.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
15
-
-
11844291391
-
FK419, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, ameliorates brain infarction associated with thrombotic focal cerebral ischemia in monkeys: comparison with tissue plasminogen activator
-
Maeda M., Moriguchi A., Mihara K., Aoki T., Takamatsu H., Matsuoka N., Mutoh S., and Goto T. FK419, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, ameliorates brain infarction associated with thrombotic focal cerebral ischemia in monkeys: comparison with tissue plasminogen activator. J. Cereb. Blood Flow Metab. 25 (2005) 108-118
-
(2005)
J. Cereb. Blood Flow Metab.
, vol.25
, pp. 108-118
-
-
Maeda, M.1
Moriguchi, A.2
Mihara, K.3
Aoki, T.4
Takamatsu, H.5
Matsuoka, N.6
Mutoh, S.7
Goto, T.8
-
16
-
-
20144374304
-
Characterization of a novel thrombotic middle cerebral artery occlusion model in monkeys that exhibits progressive hypoperfusion and robust cortical infarction
-
Maeda M., Takamatsu H., Furuichi Y., Noda A., Awaga Y., Tatsumi M., Yamamoto M., Ichise R., Nishimura S., and Matsuoka N. Characterization of a novel thrombotic middle cerebral artery occlusion model in monkeys that exhibits progressive hypoperfusion and robust cortical infarction. J. Neurosci. Methods 146 (2005) 106-115
-
(2005)
J. Neurosci. Methods
, vol.146
, pp. 106-115
-
-
Maeda, M.1
Takamatsu, H.2
Furuichi, Y.3
Noda, A.4
Awaga, Y.5
Tatsumi, M.6
Yamamoto, M.7
Ichise, R.8
Nishimura, S.9
Matsuoka, N.10
-
17
-
-
0034642165
-
Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study
-
Marler J.R., Tilley B.C., Lu M., Brott T.G., Lyden P.C., Grotta J.C., Broderick J.P., Levine S.R., Frankel M.P., Horowitz S.H., Haley Jr. E.C., Lewandowski C.A., and Kwiatkowski TP. Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. Neurology 55 (2000) 1649-1655
-
(2000)
Neurology
, vol.55
, pp. 1649-1655
-
-
Marler, J.R.1
Tilley, B.C.2
Lu, M.3
Brott, T.G.4
Lyden, P.C.5
Grotta, J.C.6
Broderick, J.P.7
Levine, S.R.8
Frankel, M.P.9
Horowitz, S.H.10
Haley Jr., E.C.11
Lewandowski, C.A.12
Kwiatkowski, TP.13
-
18
-
-
0026668270
-
Effects of vapiprost, a novel thromboxane receptor antagonist, on thrombus formation and vascular patency after thrombolysis by tissue-type plasminogen activator
-
Matsuno H., Uematsu T., Umemura K., Takiguchi Y., Wada K., and Nakashima M. Effects of vapiprost, a novel thromboxane receptor antagonist, on thrombus formation and vascular patency after thrombolysis by tissue-type plasminogen activator. Br. J. Pharmacol. 106 (1992) 533-538
-
(1992)
Br. J. Pharmacol.
, vol.106
, pp. 533-538
-
-
Matsuno, H.1
Uematsu, T.2
Umemura, K.3
Takiguchi, Y.4
Wada, K.5
Nakashima, M.6
-
19
-
-
0034746189
-
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
-
Nicole O., Docagne F., Ali C., Margaill I., Carmeliet P., MacKenzie E.T., Vivien D., and Buisson A. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nat. Med. 7 (2001) 59-64
-
(2001)
Nat. Med.
, vol.7
, pp. 59-64
-
-
Nicole, O.1
Docagne, F.2
Ali, C.3
Margaill, I.4
Carmeliet, P.5
MacKenzie, E.T.6
Vivien, D.7
Buisson, A.8
-
20
-
-
0025202161
-
Brain volume estimation from serial section measurements: a comparison of methodologies
-
Rosen G.D., and Harry J.D. Brain volume estimation from serial section measurements: a comparison of methodologies. J. Neurosci. Methods 35 (1990) 115-124
-
(1990)
J. Neurosci. Methods
, vol.35
, pp. 115-124
-
-
Rosen, G.D.1
Harry, J.D.2
-
21
-
-
0027937489
-
Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia
-
Sharkey J., and Butcher S.P. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Nature 371 (1994) 336-339
-
(1994)
Nature
, vol.371
, pp. 336-339
-
-
Sharkey, J.1
Butcher, S.P.2
-
22
-
-
0344065373
-
Recommendations for standards regarding preclinical neuroprotective and restorative drug development
-
STAIR
-
STAIR. Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30 (1999) 2752-2758
-
(1999)
Stroke
, vol.30
, pp. 2752-2758
-
-
-
23
-
-
0034943173
-
Recommendations for clinical trial evaluation of acute stroke therapies
-
STAIR-II
-
STAIR-II. Recommendations for clinical trial evaluation of acute stroke therapies. Stroke 32 (2001) 1598-1606
-
(2001)
Stroke
, vol.32
, pp. 1598-1606
-
-
-
24
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke
-
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med. 333 (1995) 1581-1587
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1581-1587
-
-
-
25
-
-
0031807664
-
Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia
-
Tsujikawa A., Ogura Y., Hiroshiba N., Miyamoto K., Kiryu J., and Honda Y. Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia. Stroke 29 (1998) 1431-1437
-
(1998)
Stroke
, vol.29
, pp. 1431-1437
-
-
Tsujikawa, A.1
Ogura, Y.2
Hiroshiba, N.3
Miyamoto, K.4
Kiryu, J.5
Honda, Y.6
-
26
-
-
0027216002
-
Evaluation of the combination of a tissue-type plasminogen activator, SUN9216, and a thromboxane A2 receptor antagonist, vapiprost, in a rat middle cerebral artery thrombosis model
-
Umemura K., Wada K., Uematsu T., and Nakashima M. Evaluation of the combination of a tissue-type plasminogen activator, SUN9216, and a thromboxane A2 receptor antagonist, vapiprost, in a rat middle cerebral artery thrombosis model. Stroke 24 (1993) 1077-1081
-
(1993)
Stroke
, vol.24
, pp. 1077-1081
-
-
Umemura, K.1
Wada, K.2
Uematsu, T.3
Nakashima, M.4
-
27
-
-
0028053156
-
Effect of 21-aminosteroid lipid peroxidation inhibitor, U74006F, in the rat middle cerebral artery occlusion model
-
Umemura K., Wada K., Uematsu T., Mizuno A., and Nakashima M. Effect of 21-aminosteroid lipid peroxidation inhibitor, U74006F, in the rat middle cerebral artery occlusion model. Eur. J. Pharmacol. 251 (1994) 69-74
-
(1994)
Eur. J. Pharmacol.
, vol.251
, pp. 69-74
-
-
Umemura, K.1
Wada, K.2
Uematsu, T.3
Mizuno, A.4
Nakashima, M.5
-
28
-
-
0028919198
-
Effect of combination of a tissue-type plasminogen activator and an endothelin receptor antagonist, FR139317, in the rat cerebral infarction model
-
Umemura K., Ishiye M., Kosuge K., and Nakashima M. Effect of combination of a tissue-type plasminogen activator and an endothelin receptor antagonist, FR139317, in the rat cerebral infarction model. Eur. J. Pharmacol. 275 (1995) 17-21
-
(1995)
Eur. J. Pharmacol.
, vol.275
, pp. 17-21
-
-
Umemura, K.1
Ishiye, M.2
Kosuge, K.3
Nakashima, M.4
-
29
-
-
0032482134
-
Dose-dependent, protective effect of FK506 against white matter changes in the rat brain after chronic cerebral ischemia
-
Wakita H., Tomimoto H., Akiguchi I., and Kimura J. Dose-dependent, protective effect of FK506 against white matter changes in the rat brain after chronic cerebral ischemia. Brain Res. 792 (1998) 105-113
-
(1998)
Brain Res.
, vol.792
, pp. 105-113
-
-
Wakita, H.1
Tomimoto, H.2
Akiguchi, I.3
Kimura, J.4
-
30
-
-
0031951510
-
Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice
-
Wang Y.F., Tsirka S.E., Strickland S., Stieg P.E., Soriano S.G., and Lipton S.A. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat. Med. 4 (1998) 228-231
-
(1998)
Nat. Med.
, vol.4
, pp. 228-231
-
-
Wang, Y.F.1
Tsirka, S.E.2
Strickland, S.3
Stieg, P.E.4
Soriano, S.G.5
Lipton, S.A.6
-
31
-
-
0033537768
-
2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science 284 (1999) 339-343
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
32
-
-
0021826450
-
Induction of reproducible brain infarction by photochemically initiated thrombosis
-
Watson B.D., Dietrich W.D., Busto R., Wachtel M.S., and Ginsberg M.D. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann. Neurol. 17 (1985) 497-504
-
(1985)
Ann. Neurol.
, vol.17
, pp. 497-504
-
-
Watson, B.D.1
Dietrich, W.D.2
Busto, R.3
Wachtel, M.S.4
Ginsberg, M.D.5
-
33
-
-
0030569031
-
Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils
-
Yagita Y., Kitagawa K., Matsushita K., Taguchi A., Mabuchi T., Ohtsuki T., Yanagihara T., and Matsumoto M. Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils. Life Sci. 59 (1996) 1643-1650
-
(1996)
Life Sci.
, vol.59
, pp. 1643-1650
-
-
Yagita, Y.1
Kitagawa, K.2
Matsushita, K.3
Taguchi, A.4
Mabuchi, T.5
Ohtsuki, T.6
Yanagihara, T.7
Matsumoto, M.8
-
34
-
-
0345251951
-
Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat
-
Zhang R.L., Zhang Z.G., and Chopp M. Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat. Neurology 52 (1999) 273-279
-
(1999)
Neurology
, vol.52
, pp. 273-279
-
-
Zhang, R.L.1
Zhang, Z.G.2
Chopp, M.3
|