Liposome-encapsulated hemoglobin ameliorates ischemic stroke in nonhuman primates: An acute study

Journal of Pharmacology and Experimental Therapeutics

Volumn 332, Issue 2, 2010, Pages 429-436

  Kawaguchi, Akira T ^a   Haida, Munetaka ^a,b   Yamano, Mariko ^c   Fukumoto, Dai ^d   Ogata, Yoshitaka ^e   Tsukada, Hideo ^d  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c Osaka Prefecture University   (Japan)

^d CENTRAL RESEARCH LABORATORY   (Japan)

^e TERUMO CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; LIPOSOME; LIPOSOME ENCAPSULATED HEMOGLOBIN; OXYGEN 15; TRM 645; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CLINICAL EVALUATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG CAPSULE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG EFFICACY; HEMODYNAMIC PARAMETERS; IMMUNOHISTOCHEMISTRY; INFUSION; METABOLIC RATE; METABOLISM; MIDDLE CEREBRAL ARTERY OCCLUSION; MONKEY; NEUROPROTECTION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIMATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; STEADY STATE;

ANIMALS; BASAL GANGLIA; BLOOD GAS ANALYSIS; BLOOD GLUCOSE; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; HEMODYNAMICS; HEMOGLOBINS; INFARCTION, MIDDLE CEREBRAL ARTERY; LIPOSOMES; MACACA FASCICULARIS; MICROTUBULE-ASSOCIATED PROTEINS; OXYGEN RADIOISOTOPES; POSITRON-EMISSION TOMOGRAPHY;

EID: 76749110723     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.160051     Document Type: Article

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