A new model of cortical stroke in the rhesus macaque

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 6, 2009, Pages 1175-1186

  West, G Alexander ^a   Golshani, Kiarash J ^b,c   Doyle, Kristian P ^c   Lessov, Nikola S ^c   Hobbs, Theodore R ^d   Kohama, Steven G ^d   Pike, Martin M ^b   Kroenke, Christopher D ^b,d   Grafe, Marjorie R ^c   Spector, Maxwell D ^c   Tobar, Eric T ^c   Simon, Roger P ^e   Stenzel Poore, Mary P ^c  

^a SWEDISH MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e LEGACY GOOD SAMARITAN HOSPITAL   (United States)

Author keywords

Cerebral ischemia; MRI; Neurologic deficit; Nonhuman primate; Rhesus macaque; Stroke

Indexed keywords

2,3,5 TRIPHENYL TETRAZOLIUM CHLORIDE; TETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CLIP; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RHESUS MONKEY; STAINING;

ANIMALS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MALE; OXAZINES;

EID: 67349087972     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.43     Document Type: Article

References (40)

1. Clark WM, Hazel JS, Beamer N, Wynn M, Coull B (1996) The initial acute phase response predicts long term stroke recovery. Stroke (Abstract) 7:128-31
2. Coceani F, Libman I, Gloor P (1966) The effect of intracarotid amobarbital injections upon experimentally induced epileptiform activity. Clin Electroencephalogr 20:542-58
3. D'Arceuil HE, Duggan M, He J, Pryor J, de Crespigny A (2006) Middle cerebral artery occlusion in Macaca fascicularis: acute and chronic stroke evolution. J Med Primatol 35:78-86
4. Davis SM, Lees KR, Albers GW, Diener HC, Markabi S, Karlsson G, Norris J (2000) Selfotel in acute ischemic stroke: possible neurotoxic effects of an NMDA antagonist. Stroke 31:347-54
5. DeGraba T, Pettigrew L (2000) Why do neuroprotective drugs work in animals but not humans? Neurol Clin 18:475-93
6. Del Zoppo GJ, Copeland BR, Harker LA, Waltz TA, Zyroff J, Hanson SR, Battenberg E (1986) Experimental acute thrombotic stroke in baboons. Stroke 17:1254-65
7. Emerich DF (2000) Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing? Trends Neurosci 23:245-6
8. Feuerstein GZ, Zaleska MM, Krams M, Wang X, Day M, Rutkowski JL, Finklestein SP, Pangalos MN, Poole M, Stiles GL, Ruffolo RR, Walsh FL (2008) Missing steps in the STAIR case: a translational medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke. J Cereb Blood Flow Metab 28:217-9
9. Furuichi Y, Maeda M, Matsuoka N, Mutoh S, Yanagihara T (2007) Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator. Exp Neurol 204:138-46
10. Furuichi Y, Maeda M, Moriguchi A, Sawamoto T, Kawa-mura A, Matsuoka N, Mutoh S, Yanagihara T (2003) Tacrolimus, a potential neuroprotective agent, ameliorates ischemic brain damage and neurologic deficits after focal cerebral ischemia in nonhuman primates. J Cereb Blood Flow Metab 23:1183-94
11. Gidday J, Shah A, Mceren R, Wang Q, Pelligrino D, Holtzman D, Park T (1999) Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J Cereb Blood Flow Metab 19:331-40
12. Grotta J (1995) Why do all drugs work in animals but none in stroke patients? 2. Neuroprotective therapy. J Intern Med 237:89-94
13. Hirouchi Y, Suzuki E, Mitsuoka C, Jin H, Kitajima S, Kohjimoto Y, Enomoto M, Kugino K (2007) Neuroima-ging and histopathological evaluation of delayed neurological damage produced by artificial occlusion of the middle cerebral artery in Cynomolgus monkeys: establishment of a monkey model for delayed cerebral ischemia. Exp Toxicol Pathol 59:9-16
14. Huang J, Mocco J, Choudhri TF, Poisik A, Popilskis SJ, Emerson R, DelaPaz RL, Khandji AG, Pinsky DJ, Connolly Jr ES (2000) A modified transorbital baboon model of reperfused stroke. Stroke 31:3054-63
15. Huang Z, Huang PL, Fishman MC, Moskowitz MA (1994) Effects of cerebral ischemia in mice deficient in neuronal nitirc oxide synthase. Science 265:1883-5
16. Jones TH, Morawetz RB, Crowell RM, Marcoux FW, FitzGibbon SJ, DeGirolami U, Ojemann RG (1981) Thresholds of focal cerebral ischemia in awake monkeys. J Neurosurg 54:773-82
17. Kapoor K, Kak VK, Singh B (2003) Morphology and comparative anatomy of circulus arteriosus cerebri in mammals. Anat Histol Embryol 32:347-55
18. Kasner SE, Demchuk AM, Berrouschot J, Schmutzhard E, Harms L, Verro P, Chalela JA, Abbur R, McGrade H, Christou I, Krieger DW (2001) Predictors of fatal brain edema in massive hemispheric ischemic stroke. Stroke 32:2117-23
19. Kito G, Nishimura A, Susumu T, Nagata R, Kuge Y, Yokota C, Minematsu K (2001) Experimental thromboembolic stroke in cynomolgus monkey. J Neurosci Methods 105:45-53
20. Li F, Liu KF, Silva MD, Omae T, Sotak CH, Fenstermacher JD, Fisher M, Hsu CY, Lin W (2000) Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: correlation with histopathology. Stroke 31: 946-54
21. Liu H, Xin L, Chan BPL, Teoh R, Tang BL, Tan YH (2002) Interferon beta administration confers a beneficial outcome in a rabbit model of thromboembolic cerebral ischemia. Neurosci Lett 327:146-8
22. Liu Y, D'Arceuil HE, Westmoreland S, He J, Duggan M, Gonzalez RG, Pryor J, de Crespigny AJ (2007) Serial diffusion tensor MRI after transient and permanent cerebral ischemia in nonhuman primates. Stroke 38:138-45
23. Mack WJ, Komotar RJ, Mocco J, Coon AL, Hoh DJ, King RG, Ducruet AF, Ransom ER, Oppermann M, DeLaPaz R, Connolly Jr ES (2003) Serial magnetic resonance imaging in experimental primate stroke: validation of MRI for pre-clinical cerebroprotective trials. Neurol Res 25:846-52
24. Maeda M, Takamatsu H, Furuichi Y, Noda A, Awaga Y, Tatsumi M, Yamamoto M, Ichise R, Nishimura S, Matsuoka N (2005) Characterization of a novel thrombotic middle cerebral artery occlusion model in monkeys that exhibits progressive hypoperfusion and robust cortical infarction. J Neurosci Methods 146:106-15
25. Murphy SJ, Kirsch JR, Zhang W, Grafe MR, West GA, del Zoppo GJ, Traystman RJ, Hum PD (2008) Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia? Comp Med 58:588-96
26. Nolte UG, Finsterbusch J, Frahm J (2000) Rapid isotropic diffusion mapping without susceptibility artifacts: whole brain studies using diffusion-weighted single-shot STEAM MR imaging. Magn Reson Med 44:731-6
27. Ostergaard L (2005) Principles of cerebral perfusion imaging by bolus tracking. J Magn Reson Imaging 22:710-7
28. Ross AM, Hurn P, Perrin N, Wood L, Carlini W, Potempa K (2007) Evidence of the peripheral inflammatory response in patients with transient ischemic attack. J Stroke Cerebrovasc Dis 16:203-7
29. Savitz SI (2007) A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke. Exp Neurol 205:20-5
30. Schmitz J, Roos C, Zischler H (2005) Primate phylogeny: molecular evidence from retroposons. Cytogenet Genome Res 108:26-37
31. Schmued LC, Hopkins KJ (2000) Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874:123-30
32. Sotak CH (2002) The role of diffusion tensor imaging in the evaluation of ischemic brain injury - a review. NMR Biomed 15:561-9
33. Spetzler RF, Selman WR, Weinstein P, Townsend J, Mehdorn M, Telles D, Crumrine RC, Macko R (1980) Chronic reversible cerebral ischemia: evaluation of a new baboon model. Neurosurgery 7:257-61
34. Stenzel-Poore MP, Stevens SL, King JS, Simon RP (2007) Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis. Stroke 38:680-5
35. Stroke Therapy Academic Industry Round Table (Fisher M. Chair) (1999) Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30:2752-8
36. Stroke Therapy Academic Industry Round Table (Fisher M. Chair) (2005) Enhancing the development and approval of acute stroke therapies: Stroke Therapy Academic Industry roundtable. Stroke 36:1808-13
37. Takamatsu H, Tsukada H, Kakiuchi T, Nishiyama S, Noda A, Umemura K (2000) Detection of reperfusion injury using PET in a monkey model of cerebral ischemia. J Nucl Med 41:1409-16
38. Tamura A, Kirino T, Sano K, Takagi K, Oka H (1990) Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat. Brain Res 510:154-7
39. Traversa R, Cicinelli P, Oliveri M, Giuseppina Palmieri M, Filippi MM, Pasqualetti P, Rossini PM (2000) Neurophysiological follow-up of motor cortical output in stroke patients. Clin Neurophysiol 111:1695-703
40. Young AR, Touzani O, Derlon JM, Sette G, MacKenzie ET, Baron JC (1997) Early reperfusion in the anesthetized baboon reduces brain damage following middle cerebral artery occlusion: a quantitative analysis of infarction volume. Stroke 28:632-8