Animal models of human genetic diseases: Do they need to be faithful to be useful?

Molecular Genetics and Genomics

Volumn 286, Issue 1, 2011, Pages 1-20

  Guénet, Jean Louis ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Animal models of human genetic diseases; Mouse genetics; Rat genetics

Indexed keywords

ALLELE; DISEASE MODEL; EPISTASIS; EXPERIMENTAL MOUSE; EXPERIMENTAL RAT; GENE IDENTIFICATION; GENE INTERACTION; GENE MUTATION; GENETIC DISORDER; GENETIC MODEL; GENOME; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; MAMMALIAN GENETICS; MULTIFACTORIAL INHERITANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; TRANSGENIC ANIMAL; TRANSGENICS;

ANIMALS; DISEASE MODELS, ANIMAL; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; HUMANS;

ANIMALIA; RATTUS;

EID: 79955496674     PISSN: 16174615     EISSN: 16174623     Source Type: Journal    
DOI: 10.1007/s00438-011-0627-y     Document Type: Review

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