Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases

Human Molecular Genetics

Volumn 5, Issue 1, 1996, Pages 1-14

  Phaneuf, Daniel ^a,g   Wakamatsu, Nobuaki ^a,h   Huang, Jing Qi ^a   Borowski, Anita ^c   Peterson, Alan C ^b   Fortunato, Sheila R ^d   Ritter, Gerd ^d   Igdoura, Suleiman A ^a   Morales, Carlos R ^a   Benoit, Guylaine ^a   Akerman, Beverly R ^a   Leclerc, Daniel ^a   Hanai, Nobuo ^e   Marth, Jamey D ^c,i   Trasler, Jacquetta M ^a   Gravel, Roy A ^a,f  

^a MCGILL UNIVERSITY   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e KYOWA HAKKO KOGYO CO LTD   (Japan)

^f RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^g HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^h UNIVERSITY OF TOKUSHIMA   (Japan)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE B; GANGLIOSIDE GM2; SIALIDASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CATABOLISM; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE DISRUPTION; MOUSE; MUSCLE WEAKNESS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RIGIDITY; SANDHOFF DISEASE; SPASTICITY; SPINAL CORD; TAY SACHS DISEASE; TREMOR;

ANIMALS; BASE SEQUENCE; BETA-N-ACETYLHEXOSAMINIDASE; BRAIN CHEMISTRY; BRAIN INJURIES; DISEASE MODELS, ANIMAL; FEMALE; G(M2) GANGLIOSIDE; GENE TARGETING; GLYCOSPHINGOLIPIDS; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PHENOTYPE; RNA, MESSENGER; SANDHOFF DISEASE; SPINAL CORD; TAY-SACHS DISEASE;

ANIMALIA; ATAXIA;

EID: 9044236158     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/5.1.1     Document Type: Article

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