A mutation in the gene encoding mitochondrial mg2+ channel MRS2 results in demyelination in the RAT

PLoS Genetics

Volumn 7, Issue 1, 2011, Pages

  Kuramoto, Takashi ^a   Kuwamura, Mitsuru ^b   Tokuda, Satoko ^a,b   Izawa, Takeshi ^b   Nakane, Yoshifumi ^a   Kitada, Kazuhiro ^a,c   Akao, Masaharu ^a   Guénet, Jean Louis ^d   Serikawa, Tadao ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Osaka City University   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; LACTIC ACID; MYELIN; PROTEIN MRS2; UNCLASSIFIED DRUG; CATION TRANSPORT PROTEIN; MITOCHONDRIAL PROTEIN; MRS2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ARTICLE; CELL SWELLING; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CONTROLLED STUDY; CYTOPLASM; DEMYELINATION; GENE INACTIVATION; GENE MUTATION; HOMEOSTASIS; HUMAN; HUMAN CELL; LACTATE BLOOD LEVEL; MALE; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL GENE; MITOCHONDRIAL MEMBRANE; MYELINATION; NEUROPATHOLOGY; NONHUMAN; OLIGODENDROGLIA; RAT; TRANSGENIC RAT; ANIMAL; DEMYELINATING DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PHENOTYPE; RNA SPLICING; TRANSGENIC ANIMAL;

RATTUS; SACCHAROMYCES CEREVISIAE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CATION TRANSPORT PROTEINS; DEMYELINATING DISEASES; MICROSCOPY, ELECTRON; MITOCHONDRIAL DISEASES; MITOCHONDRIAL PROTEINS; MUTATION; PHENOTYPE; RATS; RNA SPLICE SITES;

EID: 79851482435     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001262     Document Type: Article

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