Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus

Journal of Medicinal Chemistry

Volumn 54, Issue 8, 2011, Pages 2646-2657

  Duque, María D ^a   Ma, Chunlong ^b   Torres, Eva ^a   Wang, Jun ^c   Naesens, Lieve ^d   Juárez Jiménez, Jordi ^a   Camps, Pelayo ^a   Luque, F Javier ^a   Degrado, William F ^c   Lamb, Robert A ^b   Pinto, Lawrence H ^b   Vázquez, Santiago ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMANTADINE DERIVATIVE; BISNORADAMANTANE; ION CHANNEL; NORADAMANTANE; POLYCYCLIC AROMATIC COMPOUND; PROTEIN M2; SERINE; UNCLASSIFIED DRUG; VALINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SYNTHESIS; INFLUENZA VIRUS A; MOLECULAR MODEL; NONHUMAN; OOCYTE; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VOLTAGE CLAMP; XENOPUS;

AMANTADINE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; INFLUENZA A VIRUS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PATCH-CLAMP TECHNIQUES; PLAQUE ASSAY; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL MATRIX PROTEINS; XENOPUS;

EID: 79955451255     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101334y     Document Type: Article

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