Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus

Journal of Biological Chemistry

Volumn 283, Issue 23, 2008, Pages 15921-15931

  Ma, Chunlong ^a   Soto, Cinque S ^b   Ohigashi, Yuki ^a   Taylor, Albert ^a,d   Bournas, Vasilios ^a   Glawe, Brett ^a   Udo, Maria K ^c   DeGrado, William F ^b   Lamb, Robert A ^a   Pinto, Lawrence H ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINES; CELL MEMBRANES; METHANE; PROTEINS; VIRUSES;

ACIDIC ENVIRONMENTS; AMANTADINE; ANTIVIRAL DRUGS; CYSTEINE MUTANTS; ENDOSOME; EXPERIMENTAL DATUMS; ION CHANNELS; MEMBRANE PROTEINS; POLAR COMPOUNDS; POLAR RESIDUES; PROTEIN IONS; RIBONUCLEOPROTEIN; SPECIFIC ACTIVITIES; TRANSMEMBRANE DOMAINS; VIRUS PARTICLES; WILD TYPES;

IONS;

(2 AMINOETHYL) METHANE THIOSULFONATE; CYSTEINE; ION CHANNEL; N ETHYLMALEIMIDE; PROTEIN BM2; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; VIRUS PROTEIN; AMANTADINE; ANTIVIRUS AGENT; BM2 POLYPEPTIDE, INFLUENZA B VIRUS;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; INFLUENZA VIRUS B; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; ANIMAL; ANTIVIRAL RESISTANCE; CHEMICAL STRUCTURE; CYTOLOGY; DRUG EFFECT; ENDOSOME; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN MOTIF; VIROLOGY; XENOPUS LAEVIS;

INFLUENZA A VIRUS; INFLUENZA B VIRUS;

AMANTADINE; AMINO ACID MOTIFS; ANIMALS; ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; ENDOSOMES; INFLUENZA B VIRUS; ION CHANNELS; MODELS, MOLECULAR; MUTATION; OOCYTES; VIRAL PROTEINS; XENOPUS LAEVIS;

EID: 47049086607     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710302200     Document Type: Article

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