Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

Journal of Molecular Biology

Volumn 385, Issue 4, 2009, Pages 1127-1141

  Cady, Sarah D ^a   Mishanina, Tatiana V ^a   Hong, Mei ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

amantadine; chemical shifts; influenza M2 proton channel; magic angle spinning; solid state NMR

Indexed keywords

AMANTADINE; GLYCINE; MEMBRANE PROTEIN; MONOMER; PROTEIN M2; SERINE; TRYPTOPHAN; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CHANNEL GATING; CRYSTAL STRUCTURE; DRUG BINDING; HYDROGEN BOND; INFLUENZA VIRUS A; LIPID BILAYER; LOW TEMPERATURE; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 58149345493     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.11.022     Document Type: Article

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