Molecular Dynamics-Solvated Interaction Energy Studies of Protein-Protein Interactions: The MP1-p14 Scaffolding Complex

Journal of Molecular Biology

Volumn 379, Issue 4, 2008, Pages 787-802

  Cui, Qizhi ^a   Sulea, Traian ^a   Schrag, Joseph D ^a   Munger, Christine ^b   Hung, Ming Ni ^a   Naïm, Marwen ^a   Cygler, Miroslaw ^a,b   Purisima, Enrico O ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

binding affinity calculations; MAP kinase signaling; virtual alanine scanning; yeast two hybrid assay

Indexed keywords

ALANINE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P14; RAF PROTEIN; RAS PROTEIN; SCAFFOLD PROTEIN;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; MUTANT; MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SYNTHESIS; SOLVATED INTERACTION ENERGY; WILD TYPE;

EID: 44149094011     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.04.035     Document Type: Article

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