메뉴 건너뛰기




Volumn 26, Issue 3, 2011, Pages 421-429

Chronic alcohol exposure induces genome damage measured using the cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ANEUPLOIDY; ARTICLE; CANCER GROWTH; CELL ASSAY; CHILD; CHROMOSOMAL INSTABILITY; CHROMOSOME 17; CHROMOSOME BREAKAGE; CHROMOSOME DAMAGE; CHROMOSOME LOSS; CHROMOSOME REARRANGEMENT; CYTOKINESIS BLOCK MICRONUCLEUS CYTOME ASSAY; DAUDI CELL; DNA DAMAGE; FEMALE; GENE AMPLIFICATION; GENERAL AND MISCELLANEOUS PROCEDURES AND TECHNIQUES; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; PRESCHOOL CHILD; PRIORITY JOURNAL;

EID: 79955449806     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq110     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 0030963846 scopus 로고    scopus 로고
    • DNA damage, DNA repair, and alcohol toxicity - A review
    • Brooks, P. J. (1997) DNA damage, DNA repair, and alcohol toxicity-a review. Alcohol Clin. Exp. Res., 21, 1073-1082. (Pubitemid 27407173)
    • (1997) Alcoholism: Clinical and Experimental Research , vol.21 , Issue.6 , pp. 1073-1082
    • Brooks, P.J.1
  • 2
    • 0033645269 scopus 로고    scopus 로고
    • Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics
    • Maffei, F., Fimognari, C., Castelli, E., Stefanini, G. F., Forti, G. C. and Hrelia, P. (2000) Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics. Mutagenesis, 15, 517-523.
    • (2000) Mutagenesis , vol.15 , pp. 517-523
    • Maffei, F.1    Fimognari, C.2    Castelli, E.3    Stefanini, G.F.4    Forti, G.C.5    Hrelia, P.6
  • 3
    • 0017340425 scopus 로고
    • Association of cancer sites with tobacco and alcohol consumption and socioeconomic status of patients: interview study from the Third National Cancer Survey
    • Williams, R. R. and Horm, J. W. (1977) Association of cancer sites with tobacco and alcohol consumption and socioeconomic status of patients: interview study from the Third National Cancer Survey. J. Natl Cancer Inst., 58, 525-547. (Pubitemid 8056552)
    • (1977) Journal of the National Cancer Institute , vol.58 , Issue.3 , pp. 525-547
    • Williams, R.R.1    Horm, J.W.2
  • 5
    • 0035887773 scopus 로고    scopus 로고
    • Exploring the relation of alcohol consumption to risk of breast cancer
    • DOI 10.1093/aje/154.8.740
    • Ellison, R. C., Zhang, Y., McLennan, C. E. and Rothman, K. J. (2001) Exploring the relation of alcohol consumption to risk of breast cancer. Am. J. Epidemiol., 154, 740-747. (Pubitemid 32971495)
    • (2001) American Journal of Epidemiology , vol.154 , Issue.8 , pp. 740-747
    • Ellison, R.C.1    Zhang, Y.2    McLennan, C.E.3    Rothman, K.J.4
  • 6
    • 0027958427 scopus 로고
    • Alcoholic beverage consumption in relation to risk of breast cancer: Meta-analysis and review
    • Longnecker, M. P. (1994) Alcoholic beverage consumption in relation to risk of breast cancer: meta-analysis and review. Cancer Causes Control, 5, 73-82. (Pubitemid 24066596)
    • (1994) Cancer Causes and Control , vol.5 , Issue.1 , pp. 73-82
    • Longnecker, M.P.1
  • 7
    • 0032740553 scopus 로고    scopus 로고
    • Alcohol: The link between hormone replacement and breast cancer risk-the critical role of alcohol consumption in determining the risk of breast cancer with postmenopausal estrogen administration
    • Ballagh, S. (1999) Alcohol: the link between hormone replacement and breast cancer risk-the critical role of alcohol consumption in determining the risk of breast cancer with postmenopausal estrogen administration. Women Health Iss., 9, 338-342.
    • (1999) Women Health Iss. , vol.9 , pp. 338-342
    • Ballagh, S.1
  • 8
    • 0037389507 scopus 로고    scopus 로고
    • Roles of BRCA1 in DNA damage repair: A link between development and cancer
    • Spec No 1 R113-R123
    • Deng, C. X. and Wang, R. H. (2003) Roles of BRCA1 in DNA damage repair: a link between development and cancer. Hum. Mol. Genet., 12, Spec No 1, R113-R123.
    • (2003) Hum. Mol. Genet. , vol.12
    • Deng, C.X.1    Wang, R.H.2
  • 9
    • 0033945795 scopus 로고    scopus 로고
    • In vitro genotoxicity of ethanol and acetaldehyde in human lymphocytes and the gastrointestinal tract mucosa cells
    • DOI 10.1016/S0887-2333(00)00022-9, PII S0887233300000229
    • Blasiak, J., Trzeciak, A., Malecka-Panas, E., Drzewoski, J. and Wojewodzka, M. (2000) In vitro genotoxicity of ethanol and acetaldehyde in human lymphocytes and the gastrointestinal tract mucosa cells. Toxicol. In Vitro, 14, 287-295. (Pubitemid 30440596)
    • (2000) Toxicology in Vitro , vol.14 , Issue.4 , pp. 287-295
    • Blasiak, J.1    Trzeciak, A.2    Malecka-Panas, E.3    Drzewoski, J.4    Wojewodzka, M.5
  • 10
    • 0037112246 scopus 로고    scopus 로고
    • Chromosomal biomarkers of genomic instability relevant to cancer
    • DOI 10.1016/S1359-6446(02)02502-3, PII S1359644602025023
    • Fenech, M. (2002) Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov. Today, 7, 1128-1137. (Pubitemid 35346420)
    • (2002) Drug Discovery Today , vol.7 , Issue.22 , pp. 1128-1137
    • Fenech, M.1
  • 12
    • 0037272682 scopus 로고    scopus 로고
    • Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma
    • DOI 10.1023/A:1021399923825
    • Watters, A. D., Going, J. J., Cooke, T. G. and Bartlett, J. M. (2003) Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma. Breast Cancer Res. Treat., 77, 109-114. (Pubitemid 36197611)
    • (2003) Breast Cancer Research and Treatment , vol.77 , Issue.2 , pp. 109-114
    • Watters, A.D.1    Going, J.J.2    Cooke, T.G.3    Bartlett, J.M.S.4
  • 13
    • 0034951142 scopus 로고    scopus 로고
    • Double-strand-break-induced homologous recombination in mammalian cells
    • DOI 10.1042/0300-5127:0290196
    • Johnson, R. D. and Jasin, M. (2001) Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc. Trans., 29, 196-201. (Pubitemid 32587504)
    • (2001) Biochemical Society Transactions , vol.29 , Issue.2 , pp. 196-201
    • Johnson, R.D.1    Jasin, M.2
  • 14
    • 0035928799 scopus 로고    scopus 로고
    • New complexities for BRCA1 and BRCA2
    • DOI 10.1016/S0960-9822(01)00389-X
    • Kerr, P. and Ashworth, A. (2001) New complexities for BRCA1 and BRCA2. Curr. Biol., 11, R668-R676. (Pubitemid 32774078)
    • (2001) Current Biology , vol.11 , Issue.16
    • Kerr, P.1    Ashworth, A.2
  • 15
    • 0033106326 scopus 로고    scopus 로고
    • 2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
    • DOI 10.1016/S1097-2765(00)80466-9
    • Xu, X., Weaver, Z., Linke, S. P., Li, C., Gotay, J., Wang, X. W., Harris, C. C., Ried, T. and Deng, C. X. (1999) Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol. Cell, 3, 389-395. (Pubitemid 29290679)
    • (1999) Molecular Cell , vol.3 , Issue.3 , pp. 389-395
    • Xu, X.1    Weaver, Z.2    Linke, S.P.3    Li, C.4    Gotay, J.5    Wang, X.-W.6    Harris, C.C.7    Ried, T.8    Deng, C.-X.9
  • 17
    • 0021330367 scopus 로고
    • Disruptive effects of ethyl alcohol on mitotic chromosome segregation in diploid and haploid strains of Aspergillus nidulans
    • Kafer, E. (1984) Disruptive effects of ethyl alcohol on mitotic chromosome segregation in diploid and haploid strains of Aspergillus nidulans. Mutat. Res., 135, 53-75. (Pubitemid 14184090)
    • (1984) Mutation Research , vol.135 , Issue.1 , pp. 53-75
    • Kafer, E.1
  • 18
    • 0023909473 scopus 로고
    • Acetaldehyde-induced aneuploidy in cultured Chinese hamster cells
    • Dulout, F. N. and Furnus, C. C. (1988) Acetaldehyde-induced aneuploidy in cultured Chinese hamster cells. Mutagenesis, 3, 207-211.
    • (1988) Mutagenesis , vol.3 , pp. 207-211
    • Dulout, F.N.1    Furnus, C.C.2
  • 19
    • 0022203364 scopus 로고
    • Solutions to the kinetic problem in the micronucleus assay
    • Fenech, M. and Morley, A. (1985) Solutions to the kinetic problem in the micronucleus assay. Cytobios, 43, 233-246. (Pubitemid 16255452)
    • (1985) Cytobios , vol.43 , Issue.172-173 , pp. 233-246
    • Fenech, M.1    Morley, A.2
  • 20
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech, M. and Morley, A. A. (1985) Measurement of micronuclei in lymphocytes. Mutat. Res., 147, 29-36. (Pubitemid 15111220)
    • (1985) Mutation Research , vol.147 , Issue.1-2 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 21
    • 34250187067 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus cytome assay
    • DOI 10.1038/nprot.2007.77, PII NPROT.2007.77
    • Fenech, M. (2007) Cytokinesis-block micronucleus cytome assay. Nat. Protoc., 2, 1084-1104. (Pubitemid 46901289)
    • (2007) Nature Protocols , vol.2 , Issue.5 , pp. 1084-1104
    • Fenech, M.1
  • 22
    • 33747335092 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death
    • Fenech, M. (2006) Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death. Mutat. Res., 600, 58-66.
    • (2006) Mutat. Res. , vol.600 , pp. 58-66
    • Fenech, M.1
  • 23
    • 79955370398 scopus 로고    scopus 로고
    • accessed November 18 2010)
    • http://www.atcc.org (accessed November 18, 2010).
  • 24
    • 0014333021 scopus 로고
    • Human lymphoblastoid lines from lymph node and spleen
    • Levy, J. A., Virolainen, M. and Defendi, V. (1968) Human lymphoblastoid lines from lymph node and spleen. Cancer, 22, 517-524.
    • (1968) Cancer , vol.22 , pp. 517-524
    • Levy, J.A.1    Virolainen, M.2    Defendi, V.3
  • 25
    • 0032486088 scopus 로고    scopus 로고
    • Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53
    • DOI 10.1016/S0027-5107(97)00272-8, PII S0027510797002728
    • Greenwood, S. K., Armstrong, M. J., Hill, R. B., Bradt, C. I., Johnson, T. E., Hilliard, C. A. and Galloway, S. M. (1998) Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53. Mutat. Res., 401, 39-53. (Pubitemid 28293837)
    • (1998) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.401 , Issue.1-2 , pp. 39-53
    • Greenwood, S.K.1    Armstrong, M.J.2    Hill, R.B.3    Bradt, C.I.4    Johnson, T.E.5    Hilliard, C.A.6    Galloway, S.M.7
  • 26
    • 0028986587 scopus 로고
    • The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status
    • Zhen, W., Denault, C. M., Loviscek, K., Walter, S., Geng, L. and Vaughan, A. T. (1995) The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status. Mutat. Res., 346, 85-92.
    • (1995) Mutat. Res. , vol.346 , pp. 85-92
    • Zhen, W.1    Denault, C.M.2    Loviscek, K.3    Walter, S.4    Geng, L.5    Vaughan, A.T.6
  • 28
    • 79955366826 scopus 로고    scopus 로고
    • accessed November 18 2010)
    • http://ccr.coriell.org (accessed November 18, 2010).
  • 29
    • 0037342501 scopus 로고    scopus 로고
    • The principal phenolic and alcoholic components of wine protect human lymphocytes against hydrogen peroxide- and ionizing radiation-induced DNA damage in vitro
    • DOI 10.1093/mutage/18.2.119
    • Greenrod, W. and Fenech, M. (2003) The principal phenolic and alcoholic components of wine protect human lymphocytes against hydrogen peroxideand ionizing radiation-induced DNA damage in vitro. Mutagenesis, 18, 119-126. (Pubitemid 36336527)
    • (2003) Mutagenesis , vol.18 , Issue.2 , pp. 119-126
    • Greenrod, W.1    Fenech, M.2
  • 31
    • 0036356495 scopus 로고    scopus 로고
    • Basic FISH techniques and troubleshooting
    • Van Stedum, S. and King, W. (2002) Basic FISH techniques and troubleshooting. Methods Mol. Biol., 204, 51-63.
    • (2002) Methods Mol. Biol. , vol.204 , pp. 51-63
    • Van Stedum, S.1    King, W.2
  • 32
    • 0023214387 scopus 로고
    • Moderate alcohol consumption and the risk of breast cancer
    • Willett, W. C., Stampfer, M. J., Colditz, G. A., Rosner, B. A., Hennekens, C. H. and Speizer, F. E. (1987) Moderate alcohol consumption and the risk of breast cancer. N. Engl. J. Med., 316, 1174-1180. (Pubitemid 17069951)
    • (1987) New England Journal of Medicine , vol.316 , Issue.19 , pp. 1174-1180
    • Willett, W.C.1    Stampfer, M.J.2    Colditz, G.A.3
  • 35
    • 33745685857 scopus 로고    scopus 로고
    • Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk
    • El-Zein, R. A., Schabath, M. B., Etzel, C. J., Lopez, M. S., Franklin, J. D. and Spitz, M. R. (2006) Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk. Cancer Res., 66, 6449-6456.
    • (2006) Cancer Res. , vol.66 , pp. 6449-6456
    • El-Zein, R.A.1    Schabath, M.B.2    Etzel, C.J.3    Lopez, M.S.4    Franklin, J.D.5    Spitz, M.R.6
  • 36
    • 0034650339 scopus 로고    scopus 로고
    • Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families
    • Rothfuss, A., Schutz, P., Bochum, S., Volm, T., Eberhardt, E., Kreienberg, R., Vogel, W. and Speit, G. (2000) Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families. Cancer Res., 60, 390-394. (Pubitemid 30070767)
    • (2000) Cancer Research , vol.60 , Issue.2 , pp. 390-394
    • Rothfuss, A.1    Schutz, P.2    Bochum, S.3    Volm, T.4    Eberhardt, E.5    Kreienberg, R.6    Vogel, W.7    Speit, G.8
  • 37
    • 27844582230 scopus 로고    scopus 로고
    • Moderate acute intake of de-alcoholised red wine, but not alcohol, is protective against radiation-induced DNA damage ex vivo - Results of a comparative in vivo intervention study in younger men
    • DOI 10.1016/j.mrfmmm.2005.03.031, PII S0027510705002848, Mechanistic Approaches to Chemoprevention of Mutation and Cancer
    • Greenrod,W., Stockley, C. S., Burcham, P.,Abbey,M. and Fenech,M. (2005) Moderate acute intake of de-alcoholized red wine, but not alcohol, is protective against radiation-induced DNA damage ex vivo-results of a comparative in vivo intervention study in younger men. Mutat. Res., 591, 290-301. (Pubitemid 41654856)
    • (2005) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.591 , Issue.1-2 , pp. 290-301
    • Greenrod, W.1    Stockley, C.S.2    Burcham, P.3    Abbey, M.4    Fenech, M.5
  • 38
    • 0034693730 scopus 로고    scopus 로고
    • The in vitro micronucleus technique
    • Fenech, M. (2000) The in vitro micronucleus technique. Mutat. Res., 455, 81-95.
    • (2000) Mutat. Res. , vol.455 , pp. 81-95
    • Fenech, M.1
  • 39
    • 0028869543 scopus 로고
    • Chromosomal damages by ethanol and acetaldehyde in Saccharomyces cerevisiae as studied by pulsed field gel electrophoresis
    • Ristow, H., Seyfarth, A. and Lochmann, E. R. (1995) Chromosomal damages by ethanol and acetaldehyde in Saccharomyces cerevisiae as studied by pulsed field gel electrophoresis. Mutat. Res., 326, 165-170.
    • (1995) Mutat. Res. , vol.326 , pp. 165-170
    • Ristow, H.1    Seyfarth, A.2    Lochmann, E.R.3
  • 41
    • 0025168419 scopus 로고
    • DNA cleavage during ethanol metabolism: Role of superoxide radicals and catalytic iron
    • DOI 10.1016/0024-3205(90)90553-4
    • Rajasinghe, H., Jayatilleke, E. and Shaw, S. (1990) DNA cleavage during ethanol metabolism: role of superoxide radicals and catalytic iron. Life Sci., 47, 807-814. (Pubitemid 20286239)
    • (1990) Life Sciences , vol.47 , Issue.9 , pp. 807-814
    • Rajasinghe, H.1    Jayatilleke, E.2    Shaw, S.3
  • 42
    • 0029043990 scopus 로고
    • Acetaldehyde: Genotoxicity and cytotoxicity in human lymphocytes
    • Singh, N. P. and Khan, A. (1995) Acetaldehyde: genotoxicity and cytotoxicity in human lymphocytes. Mutat. Res., 337, 9-17.
    • (1995) Mutat. Res. , vol.337 , pp. 9-17
    • Singh, N.P.1    Khan, A.2
  • 43
    • 0022359190 scopus 로고
    • Induction and persistence of SCE-inducing damage in human lymphocytes exposed to vinyl acetate and acetaldehyde in vitro
    • He, S. M. and Lambert, B. (1985) Induction and persistence of SCEinducing damage in human lymphocytes exposed to vinyl acetate and acetaldehyde in vitro. Mutat. Res., 158, 201-208. (Pubitemid 16187980)
    • (1985) Mutation Research , vol.158 , Issue.3 , pp. 201-208
    • He, S.-M.1    Lambert, B.2
  • 44
    • 0034066102 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils
    • Umegaki, K. and Fenech, M. (2000) Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis, 15, 261-269. (Pubitemid 30312718)
    • (2000) Mutagenesis , vol.15 , Issue.3 , pp. 261-269
    • Umegaki, K.1    Fenech, M.2
  • 45
    • 0037340936 scopus 로고    scopus 로고
    • Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay
    • DOI 10.1093/mutage/18.2.187
    • Thomas, P., Umegaki, K. and Fenech, M. (2003) Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesisblock micronucleus assay. Mutagenesis, 18, 187-194. (Pubitemid 36336536)
    • (2003) Mutagenesis , vol.18 , Issue.2 , pp. 187-194
    • Thomas, P.1    Umegaki, K.2    Fenech, M.3
  • 46
    • 78650664775 scopus 로고    scopus 로고
    • Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells
    • Fenech, M., Kirsch-Volders, M., Natarajan, A. T. et al. (2010) "Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells". Mutagenesis, 26, 125-132.
    • (2010) Mutagenesis , vol.26 , pp. 125-132
    • Fenech, M.1    Kirsch-Volders, M.2    Natarajan, A.T.3
  • 47
    • 23144451094 scopus 로고    scopus 로고
    • Mechanisms of alcohol-associated cancers: Introduction and summary of the symposium
    • DOI 10.1016/j.alcohol.2005.05.001, PII S074183290500090X
    • Purohit, V., Khalsa, J. and Serrano, J. (2005) "Mechanisms of alcoholassociated cancers: introduction and summary of the symposium". Alcohol, 35, 155-160. (Pubitemid 41079919)
    • (2005) Alcohol , vol.35 , Issue.3 , pp. 155-160
    • Purohit, V.1    Khalsa, J.2    Serrano, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.