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Volumn 26, Issue 3, 2011, Pages 359-369

Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUDARABINE; FLUOROURACIL; GEMCITABINE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; IFOSFAMIDE; METHOTREXATE; MITOMYCIN C; PROTEIN P53; RALTITREXED; TAXANE DERIVATIVE; VINCRISTINE;

EID: 79955411778     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq102     Document Type: Article
Times cited : (59)

References (100)
  • 1
    • 0025350619 scopus 로고
    • Antineoplastic drugs in 1990. A review (Part II)
    • Black, D. J. and Livingston, R. B. (1990) Antineoplastic drugs in 1990. A review (Part II). Drugs, 39, 652-673.
    • (1990) Drugs , vol.39 , pp. 652-673
    • Black, D.J.1    Livingston, R.B.2
  • 2
    • 0025256032 scopus 로고
    • Antineoplastic drugs in 1990. A review (Part I)
    • Black, D. J. and Livingston, R. B. (1990) Antineoplastic drugs in 1990. A review (Part I). Drugs, 39, 489-501.
    • (1990) Drugs , vol.39 , pp. 489-501
    • Black, D.J.1    Livingston, R.B.2
  • 3
    • 12444345581 scopus 로고
    • Chemotherapeutic agents: Cancer chemotherapy
    • Harper, H. A., Rodwel V. W. and Mayes, P. A. (eds), Los Altos, CA, USA.
    • Salmon, S. and Apple, M. (1979) Chemotherapeutic agents: cancer chemotherapy. In Harper, H. A., Rodwel, V. W. and Mayes, P. A. (eds), Physiological Chemistry. Los Altos, CA, USA. pp. 471-503.
    • (1979) Physiological Chemistry , pp. 471-503
    • Salmon, S.1    Apple, M.2
  • 5
    • 33845410111 scopus 로고    scopus 로고
    • Preventing occupational exposures to antineoplastic drugs in health care settings
    • Connor, T. H. and McDiarmid, M. A. (2006) Preventing occupational exposures to antineoplastic drugs in health care settings. CA Cancer J. Clin., 56, 354-365. (Pubitemid 44903909)
    • (2006) Ca-A Cancer Journal for Clinicians , vol.56 , Issue.6 , pp. 354-365
    • Connor, T.H.1    McDiarmid, M.A.2
  • 14
    • 0026592892 scopus 로고
    • Leukaemia and reproductive outcome among nurses handling antineoplastic drugs
    • Skov, T., Maarup, B., Olsen, J., Rorth, M., Winthereik, H. and Lynge, E. (1992) Leukaemia and reproductive outcome among nurses handling antineoplastic drugs. Br. J. Ind. Med., 49, 855-861.
    • (1992) Br. J. Ind. Med. , vol.49 , pp. 855-861
    • Skov, T.1    Maarup, B.2    Olsen, J.3    Rorth, M.4    Winthereik, H.5    Lynge, E.6
  • 15
    • 0018785705 scopus 로고
    • Mutagenicity in urine of nurses handling cytostatic drugs
    • Falck, K., Grohn, P., Sorsa, M., Vainio, H., Heinonen, E. and Holsti, L. R. (1979) Mutagenicity in urine of nurses handling cytostatic drugs. Lancet, 1, 1250-1251.
    • (1979) Lancet , vol.1 , pp. 1250-1251
    • Falck, K.1    Grohn, P.2    Sorsa, M.3    Vainio, H.4    Heinonen, E.5    Holsti, L.R.6
  • 16
    • 0019905836 scopus 로고
    • Risk of handling injectable antineoplastic agents
    • Anderson,R.W., Puckett, W.H., Jr.,Dana, W. J.,Nguyen, T. V., Theiss, J. C. and Matney, T. S. (1982) Risk of handling injectable antineoplastic agents. American Journal of Hospital Pharmacy, 39, 1881-1887. (Pubitemid 12002311)
    • (1982) American Journal of Hospital Pharmacy , vol.39 , Issue.11 , pp. 1881-1887
    • Anderson, R.W.1    Puckett Jr., W.H.2    Dana, W.J.3
  • 18
    • 0023951013 scopus 로고
    • Ambient monitoring of cyclophosphamide in manufacture and hospitals
    • Pyy, L., Sorsa, M. and Hakala, E. (1988) Ambient monitoring of cyclophosphamide in manufacture and hospitals. Am. Ind. Hyg. Assoc. J., 49, 314-317.
    • (1988) Am. Ind. Hyg. Assoc. J. , vol.49 , pp. 314-317
    • Pyy, L.1    Sorsa, M.2    Hakala, E.3
  • 19
  • 22
    • 0028079554 scopus 로고
    • Assessment of occupational exposure of pharmaceutical plant workers to 5- fluorouracil: Determination of α-fluoro-β-alanine in urine
    • Sessink, P. J., Timmersmans, J. L., Anzion, R. B. and Bos, R. P. (1994) Assessment of occupational exposure of pharmaceutical plant workers to 5-fluorouracil. Determination of alpha-fluoro-beta-alanine in urine. J. Occup. Med., 36, 79-83. (Pubitemid 24020694)
    • (1994) Journal of Occupational Medicine , vol.36 , Issue.1 , pp. 79-83
    • Sessink, P.J.M.1    Timmersmans, J.L.2    Anzion, R.B.M.3    Bos, R.P.4
  • 23
    • 0028261134 scopus 로고
    • Environmental contamination and assessment of exposure to antineoplastic agents by determination of cyclophosphamide in urine of exposed pharmacy technicians: Is skin absorption an important exposure route?
    • Sessink, P. J., Van de Kerkhof, M. C., Anzion, R. B., Noordhoek, J. and Bos, R. P. (1994) Environmental contamination and assessment of exposure to antineoplastic agents by determination of cyclophosphamide in urine of exposed pharmacy technicians: is skin absorption an important exposure route? Arch. Environ. Health, 49, 165-169. (Pubitemid 24153799)
    • (1994) Archives of Environmental Health , vol.49 , Issue.3 , pp. 165-169
    • Sessink, P.J.M.1    Van De Kerkhof, M.C.A.2    Anzion, R.B.M.3    Noordhoek, J.4    Bos, R.P.5
  • 24
    • 0029987302 scopus 로고    scopus 로고
    • Monitoring occupational exposure to cancer chemotherapy drugs
    • Baker, E. S. and Connor, T. H. (1996) Monitoring occupational exposure to cancer chemotherapy drugs. Am. J. Health Syst. Pharm., 53, 2713-2723. (Pubitemid 26386655)
    • (1996) American Journal of Health-System Pharmacy , vol.53 , Issue.22 , pp. 2713-2723
    • Baker, E.S.1    Connor, T.H.2
  • 26
    • 0032941875 scopus 로고    scopus 로고
    • Drugs hazardous to healthcare workers. Evaluation of methods for monitoring occupational exposure to cytostatic drugs
    • DOI 10.2165/00002018-199920040-00004
    • Sessink, P. J. and Bos, R. P. (1999) Drugs hazardous to healthcare workers. Evaluation of methods for monitoring occupational exposure to cytostatic drugs. Drug Saf., 20, 347-359. (Pubitemid 29196911)
    • (1999) Drug Safety , vol.20 , Issue.4 , pp. 347-359
    • Sessink, P.J.M.1    Bos, R.P.2
  • 28
    • 23644431539 scopus 로고    scopus 로고
    • Genotoxic effects in a population of nurses handling antineoplastic drugs, and relationship with genetic polymorphisms in DNA repair enzymes
    • DOI 10.1002/ajim.20189
    • Laffon, B., Teixeira, J. P., Silva, S., Loureiro, J., Torres, J., Pasaro, E., Mendez, J. and Mayan, O. (2005) Genotoxic effects in a population of nurses handling antineoplastic drugs, and relationship with genetic polymorphisms in DNA repair enzymes. Am. J. Ind. Med., 48, 128-136. (Pubitemid 41134215)
    • (2005) American Journal of Industrial Medicine , vol.48 , Issue.2 , pp. 128-136
    • Laffon, B.1    Teixeira, J.P.2    Silva, S.3    Loureiro, J.4    Torres, J.5    Pasaro, E.6    Mendez, J.7    Mayan, O.8
  • 29
    • 36049052510 scopus 로고    scopus 로고
    • Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs
    • DOI 10.1093/mutage/gem032
    • Rekhadevi, P. V., Sailaja, N., Chandrasekhar, M., Mahboob, M., Rahman, M. F. and Grover, P. (2007) Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs. Mutagenesis, 22, 395-401. (Pubitemid 350098495)
    • (2007) Mutagenesis , vol.22 , Issue.6 , pp. 395-401
    • Rekhadevi, P.V.1    Sailaja, N.2    Chandrasekhar, M.3    Mahboob, M.4    Rahman, M.F.5    Grover, P.6
  • 30
    • 34547784016 scopus 로고    scopus 로고
    • Occupational exposure to antineoplastic agents induces a high level of chromosome damage. Lack of an effect of GST polymorphisms
    • DOI 10.1016/j.taap.2007.05.006, PII S0041008X07002281
    • Testa, A., Giachelia, M., Palma, S., Appolloni, M., Padua, L., Tranfo, G., Spagnoli, M., Tirindelli, D. and Cozzi, R. (2007) Occupational exposure to antineoplastic agents induces a high level of chromosome damage. Lack of an effect of GST polymorphisms. Toxicol. Appl. Pharmacol., 223, 46-55. (Pubitemid 47224967)
    • (2007) Toxicology and Applied Pharmacology , vol.223 , Issue.1 , pp. 46-55
    • Testa, A.1    Giachelia, M.2    Palma, S.3    Appolloni, M.4    Padua, L.5    Tranfo, G.6    Spagnoli, M.7    Tirindelli, D.8    Cozzi, R.9
  • 32
    • 57649186928 scopus 로고    scopus 로고
    • Longitudinal biomonitoring of nurses handling antineoplastic drugs
    • Mader, R. M., Kokalj, A., Kratochvil, E., Pilger, A. and Rudiger, H. W. (2008) Longitudinal biomonitoring of nurses handling antineoplastic drugs. J. Clin. Nurs., 18, 263-269.
    • (2008) J. Clin. Nurs. , vol.18 , pp. 263-269
    • Mader, R.M.1    Kokalj, A.2    Kratochvil, E.3    Pilger, A.4    Rudiger, H.W.5
  • 33
    • 67349260754 scopus 로고    scopus 로고
    • Assessment of genotoxic risks in Croatian health care workers occupationally exposed to cytotoxic drugs: A multi-biomarker approach
    • Kopjar, N., Garaj-Vrhovac, V., Kasuba, V., Rozgaj, R., Ramic, S., Pavlica, V. and Zeljezic, D. (2009) Assessment of genotoxic risks in Croatian health care workers occupationally exposed to cytotoxic drugs: a multi-biomarker approach. Int. J. Hyg. Environ. Health, 212, 414-431.
    • (2009) Int. J. Hyg. Environ. Health , vol.212 , pp. 414-431
    • Kopjar, N.1    Garaj-Vrhovac, V.2    Kasuba, V.3    Rozgaj, R.4    Ramic, S.5    Pavlica, V.6    Zeljezic, D.7
  • 35
    • 61649097739 scopus 로고    scopus 로고
    • Occupational risk assessment of genotoxicity and oxidative stress in workers handling anti-neoplastic drugs during a working week
    • Rombaldi, F., Cassini, C., Salvador, M., Saffi, J. and Erdtmann, B. (2009) Occupational risk assessment of genotoxicity and oxidative stress in workers handling anti-neoplastic drugs during a working week. Mutagenesis, 24, 143-148.
    • (2009) Mutagenesis , vol.24 , pp. 143-148
    • Rombaldi, F.1    Cassini, C.2    Salvador, M.3    Saffi, J.4    Erdtmann, B.5
  • 36
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N. P., McCoy, M. T., Tice, R. R. and Schneider, E. L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 40
    • 0034694109 scopus 로고    scopus 로고
    • Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay
    • Maluf, S. W. and Erdtmann, B. (2000) Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay. Mutat. Res., 471, 21-27.
    • (2000) Mutat. Res. , vol.471 , pp. 21-27
    • Maluf, S.W.1    Erdtmann, B.2
  • 41
    • 0035172448 scopus 로고    scopus 로고
    • Application of the alkaline comet assay in human biomonitoring for genotoxicity: A study on Croatian medical personnel handling antineoplastic drugs
    • Kopjar, N. and Garaj-Vrhovac, V. (2001) Application of the alkaline comet assay in human biomonitoring for genotoxicity: a study on Croatian medical personnel handling antineoplastic drugs. Mutagenesis, 16, 71-78. (Pubitemid 32050829)
    • (2001) Mutagenesis , vol.16 , Issue.1 , pp. 71-78
    • Kopjar, N.1    Garaj-Vrhovac, V.2
  • 42
    • 24044449663 scopus 로고    scopus 로고
    • Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points
    • DOI 10.1093/mutage/gei048
    • Deng, H., Zhang, M., He, J., Wu, W., Jin, L., Zheng, W., Lou, J. and Wang, B. (2005) Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points. Mutagenesis, 20, 351-357. (Pubitemid 41219864)
    • (2005) Mutagenesis , vol.20 , Issue.5 , pp. 351-357
    • Deng, H.1    Zhang, M.2    He, J.3    Wu, W.4    Jin, L.5    Zheng, W.6    Lou, J.7    Wang, B.8
  • 45
    • 33846034002 scopus 로고    scopus 로고
    • Genotoxic risks to nurses from contamination of the work environment with antineoplastic drugs in Japan
    • DOI 10.1539/joh.48.517
    • Yoshida, J., Kosaka, H., Tomioka, K. and Kumagai, S. (2006) Genotoxic risks to nurses from contamination of the work environment with antineoplastic drugs in Japan. J. Occup. Health, 48, 517-522. (Pubitemid 46057884)
    • (2006) Journal of Occupational Health , vol.48 , Issue.6 , pp. 517-522
    • Yoshida, J.1    Kosaka, H.2    Tomioka, K.3    Kumagai, S.4
  • 46
    • 40349114255 scopus 로고    scopus 로고
    • Assessment of DNA damage in Japanese nurses handling antineoplastic drugs by the comet assay
    • DOI 10.1539/joh.50.7
    • Sasaki, M., Dakeishi, M., Hoshi, S., Ishii, N. and Murata, K. (2008) Assessment of DNA damage in Japanese nurses handling antineoplastic drugs by the comet assay. J. Occup. Health, 50, 7-12. (Pubitemid 351680002)
    • (2008) Journal of Occupational Health , vol.50 , Issue.1 , pp. 7-12
    • Sasaki, M.1    Dakeishi, M.2    Hoshi, S.3    Ishii, N.4    Murata, K.5
  • 47
    • 73249122080 scopus 로고    scopus 로고
    • Evaluation of a suitable DNA damage biomarker for human biomonitoring of exposed workers
    • Cavallo, D., Ursini, C. L., Rondinone, B. and Iavicoli, S. (2009) Evaluation of a suitable DNA damage biomarker for human biomonitoring of exposed workers. Environ. Mol. Mutagen., 50, 781-790.
    • (2009) Environ. Mol. Mutagen. , vol.50 , pp. 781-790
    • Cavallo, D.1    Ursini, C.L.2    Rondinone, B.3    Iavicoli, S.4
  • 48
    • 0023088299 scopus 로고
    • A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines
    • Doetsch, P. W., Henner, W. D., Cunningham, R. P., Toney, J. H. and Helland, D. E. (1987) A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines. Mol. Cell. Biol., 7, 26-32. (Pubitemid 17230381)
    • (1987) Molecular and Cellular Biology , vol.7 , Issue.1 , pp. 26-32
    • Doetsch, P.W.1    Henner, W.D.2    Cunningham, R.P.3
  • 49
    • 0026533905 scopus 로고
    • Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine- DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization
    • Boiteux, S., Gajewski, E., Laval, J. and Dizdaroglu, M. (1992) Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine- DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry, 31, 106-110.
    • (1992) Biochemistry , vol.31 , pp. 106-110
    • Boiteux, S.1    Gajewski, E.2    Laval, J.3    Dizdaroglu, M.4
  • 50
    • 0027375157 scopus 로고
    • Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA
    • Collins, A. R., Duthie, S. J. and Dobson, V. L. (1993) Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis, 14, 1733-1735. (Pubitemid 23290881)
    • (1993) Carcinogenesis , vol.14 , Issue.9 , pp. 1733-1735
    • Collins, A.R.1    Duthie, S.J.2    Dobson, V.L.3
  • 51
    • 0014872311 scopus 로고
    • Studies in mouse L-cells on the incorporation of 1-beta-D- arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5#- triphosphate
    • Graham, F. L. and Whitmore, G. F. (1970) Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5#- triphosphate. Cancer Res., 30, 2636-2644.
    • (1970) Cancer Res. , vol.30 , pp. 2636-2644
    • Graham, F.L.1    Whitmore, G.F.2
  • 52
    • 0023608923 scopus 로고
    • Detection of 1-β-D-arabinofuranosylcytosine incorporation into DNA in vivo
    • Spriggs, D., Robbins, G., Ohno, Y. and Kufe, D. (1987) Detection of 1- beta-D-arabinofuranosylcytosine incorporation into DNA in vivo. Cancer Res., 47, 6532-6536. (Pubitemid 18019650)
    • (1987) Cancer Research , vol.47 , Issue.24 , pp. 6532-6536
    • Spriggs, D.1    Robbins, G.2    Ohno, Y.3    Kufe, D.4
  • 53
    • 0025907152 scopus 로고
    • The mode of action of 1-beta-Darabinofuranosylcytosine in inhibiting DNA repair; New evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells
    • Gedik, C. M. and Collins, A. R. (1991) The mode of action of 1-beta-Darabinofuranosylcytosine in inhibiting DNA repair; new evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells. Mutat. Res., 254, 231-237.
    • (1991) Mutat. Res. , vol.254 , pp. 231-237
    • Gedik, C.M.1    Collins, A.R.2
  • 54
    • 0032853153 scopus 로고    scopus 로고
    • The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis ('comet') assay in metabolically-competent MCL-5 cells
    • DOI 10.1016/S1383-5718(99)00116-3, PII S1383571899001163
    • Martin, F. L., Cole, K. J., Orme, M. H., Grover, P. L., Phillips, D. H. and Venitt, S. (1999) The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis ('comet') assay in metabolically-competent MCL-5 cells. Mutat. Res., 445, 21-43. (Pubitemid 29474932)
    • (1999) Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.445 , Issue.1 , pp. 21-43
    • Martin, F.L.1    Cole, K.J.2    Orme, M.H.3    Grover, P.L.4    Phillips, D.H.5    Venitt, S.6
  • 55
    • 1842766408 scopus 로고    scopus 로고
    • Cytogenetic biomarkers and genetic polymorphisms
    • DOI 10.1016/j.toxlet.2003.12.042, PII S0378427403005113
    • Norppa, H. (2004) Cytogenetic biomarkers and genetic polymorphisms. Toxicol. Lett., 149, 309-334. (Pubitemid 38469850)
    • (2004) Toxicology Letters , vol.149 , Issue.1-3 , pp. 309-334
    • Norppa, H.1
  • 56
    • 0033795121 scopus 로고    scopus 로고
    • Biological indicators of genotoxic risk and metabolic polymorphisms
    • Pavanello, S. and Clonfero, E. (2000) Biological indicators of genotoxic risk and metabolic polymorphisms. Mutat. Res., 463, 285-308.
    • (2000) Mutat. Res. , vol.463 , pp. 285-308
    • Pavanello, S.1    Clonfero, E.2
  • 57
    • 0035977862 scopus 로고    scopus 로고
    • Genetic variability in susceptibility and response to toxicants
    • DOI 10.1016/S0378-4274(01)00278-8, PII S0378427401002788
    • Ingelman-Sundberg, M. (2001) Genetic variability in susceptibility and response to toxicants. Toxicol. Lett., 120, 259-268. (Pubitemid 32375092)
    • (2001) Toxicology Letters , vol.120 , Issue.1-3 , pp. 259-268
    • Ingelman-Sundberg, M.1
  • 60
    • 0037037822 scopus 로고    scopus 로고
    • The p53 network in lung carcinogenesis
    • DOI 10.1038/sj.onc.1205563
    • Robles, A. I., Linke, S. P. and Harris, C. C. (2002) The p53 network in lung carcinogenesis. Oncogene, 21, 6898-6907. (Pubitemid 35221936)
    • (2002) Oncogene , vol.21 , Issue.45 REV. ISS. 5 , pp. 6898-6907
    • Robles, A.I.1    Linke, S.P.2    Harris, C.C.3
  • 62
    • 1642487256 scopus 로고    scopus 로고
    • P53 Codon 72 Polymorphism and Cervical Neoplasia: A Meta-Analysis Review
    • DOI 10.1158/1055-9965.EPI-083-3
    • Koushik, A., Platt, R. W. and Franco, E. L. (2004) p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review. Cancer Epidemiol. Biomarkers Prev., 13, 11-22. (Pubitemid 38116615)
    • (2004) Cancer Epidemiology Biomarkers and Prevention , vol.13 , Issue.1 , pp. 11-22
    • Koushik, A.1    Platt, R.W.2    Franco, E.L.3
  • 63
    • 0035808621 scopus 로고    scopus 로고
    • Determination of 5-fluorouracil in environmental samples by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection
    • DOI 10.1016/S0378-4347(00)00377-7, PII S0378434700003777
    • Micoli, G., Turci, R., Arpellini, M. and Minoia, C. (2001) Determination of 5-fluorouracil in environmental samples by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B Biomed. Sci. Appl., 750, 25-32. (Pubitemid 33648326)
    • (2001) Journal of Chromatography B: Biomedical Sciences and Applications , vol.750 , Issue.1 , pp. 25-32
    • Micoli, G.1    Turci, R.2    Arpellini, M.3    Minoia, C.4
  • 64
    • 0032772052 scopus 로고    scopus 로고
    • Determination of cyclophosphamide and ifosphamide in urine at trace levels by gas chromatography/tandem mass spectrometry
    • Sannolo, N., Miraglia, N., Biglietto, M., Acampora, A. and Malorni, A. (1999) Determination of cyclophosphamide and ifosphamide in urine at trace levels by gas chromatography/tandem mass spectrometry. J. Mass Spectrom., 34, 845-849.
    • (1999) J. Mass Spectrom. , vol.34 , pp. 845-849
    • Sannolo, N.1    Miraglia, N.2    Biglietto, M.3    Acampora, A.4    Malorni, A.5
  • 65
    • 36348987180 scopus 로고    scopus 로고
    • Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant
    • Moretti, M., Dell'Omo, M., Villarini, M., Pastorelli, R., Muzi, G., Airoldi, L. and Pasquini, R. (2007) Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant. BMC Public Health, 7, 270.
    • (2007) BMC Public Health , vol.7 , pp. 270
    • Moretti, M.1    Dell'Omo, M.2    Villarini, M.3    Pastorelli, R.4    Muzi, G.5    Airoldi, L.6    Pasquini, R.7
  • 66
    • 52149101175 scopus 로고    scopus 로고
    • Evaluation of primary DNA damage, cytogenetic biomarkers and genetic polymorphisms for CYP1A1 and GSTM1 in road tunnel construction workers
    • Villarini, M., Moretti, M., Fatigoni, C., Agea, E., Dominici, L., Mattioli, A., Volpi, R. and Pasquini, R. (2008) Evaluation of primary DNA damage, cytogenetic biomarkers and genetic polymorphisms for CYP1A1 and GSTM1 in road tunnel construction workers. J. Toxicol. Environmental Health, 71, 1430-1439.
    • (2008) J. Toxicol. Environmental Health , vol.71 , pp. 1430-1439
    • Villarini, M.1    Moretti, M.2    Fatigoni, C.3    Agea, E.4    Dominici, L.5    Mattioli, A.6    Volpi, R.7    Pasquini, R.8
  • 67
    • 0032875309 scopus 로고    scopus 로고
    • Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: Analysis by alkaline single cell gel electrophoresis and cytogenetic methods
    • Andreoli, C., Leopardi, P., Rossi, S. and Crebelli, R. (1999) Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: analysis by alkaline single cell gel electrophoresis and cytogenetic methods. Mutagenesis, 14, 497-504.
    • (1999) Mutagenesis , vol.14 , pp. 497-504
    • Andreoli, C.1    Leopardi, P.2    Rossi, S.3    Crebelli, R.4
  • 68
    • 23044478948 scopus 로고    scopus 로고
    • Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: Evidence of xenobiotic stress and impaired antioxidant capacity
    • DOI 10.1007/s10620-005-2790-7
    • Rahman, S. H., Nanny, C., Ibrahim, K., O'Reilly, D., Larvin, M., Kingsnorth, A. J. and McMahon, M. J. (2005) Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity. Dig. Dis. Sci., 50, 1376-1383. (Pubitemid 41184772)
    • (2005) Digestive Diseases and Sciences , vol.50 , Issue.7 , pp. 1376-1383
    • Rahman, S.H.1    Nanny, C.2    Ibrahim, K.3    O'Reilly, D.4    Larvin, M.5    Kingsnorth, A.J.6    McMahon, M.J.7
  • 70
    • 44649202871 scopus 로고    scopus 로고
    • Statistical issues in the use of the comet assay
    • Lovell, D. P. and Omori, T. (2008) Statistical issues in the use of the comet assay. Mutagenesis, 23, 171-182.
    • (2008) Mutagenesis , vol.23 , pp. 171-182
    • Lovell, D.P.1    Omori, T.2
  • 71
    • 0037342116 scopus 로고    scopus 로고
    • Statistics of the Comet assay: A key to discriminate between genotoxic effects
    • DOI 10.1093/mutage/18.2.159
    • Duez, P., Dehon, G., Kumps, A. and Dubois, J. (2003) Statistics of the Comet assay: a key to discriminate between genotoxic effects. Mutagenesis, 18, 159-166. (Pubitemid 36336533)
    • (2003) Mutagenesis , vol.18 , Issue.2 , pp. 159-166
    • Duez, P.1    Dehon, G.2    Kumps, A.3    Dubois, J.4
  • 72
    • 0037339240 scopus 로고    scopus 로고
    • Aspects of design and statistical analysis in the Comet assay
    • DOI 10.1093/mutage/18.2.167
    • Wiklund, S. J. and Agurell, E. (2003) Aspects of design and statistical analysis in the Comet assay. Mutagenesis, 18, 167-175. (Pubitemid 36336534)
    • (2003) Mutagenesis , vol.18 , Issue.2 , pp. 167-175
    • Wiklund, S.J.1    Agurell, E.2
  • 73
    • 0026602463 scopus 로고
    • High-dose combination alkylating agents with autologous bone-marrow support in patients with breast cancer: Preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay
    • Tice, R. R., Strauss, G. H. and Peters, W. P. (1992) High-dose combination alkylating agents with autologous bone-marrow support in patients with breast cancer: preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay. Mutat. Res., 271, 101-113.
    • (1992) Mutat. Res. , vol.271 , pp. 101-113
    • Tice, R.R.1    Strauss, G.H.2    Peters, W.P.3
  • 74
    • 0031557167 scopus 로고    scopus 로고
    • Validation of chromatographic methods in biomedical analysis. Viewpoint and discussion
    • DOI 10.1016/S0378-4347(96)00297-6, PII S0378434796002976
    • Causon, R. (1997) Validation of chromatographic methods in biomedical analysis. Viewpoint and discussion. J. Chromatogr. B Biomed. Sci. Appl., 689, 175-180. (Pubitemid 27089650)
    • (1997) Journal of Chromatography B: Biomedical Applications , vol.689 , Issue.1 , pp. 175-180
    • Causon, R.1
  • 77
    • 0021955455 scopus 로고
    • Guidelines for handling parenteral antineoplastics. Council on Scientific Affairs (American Medical Association)
    • AMA
    • AMA (1985) Guidelines for handling parenteral antineoplastics. Council on Scientific Affairs (American Medical Association). JAMA, 253, 1590-1592.
    • (1985) JAMA , vol.253 , pp. 1590-1592
  • 78
    • 0022627932 scopus 로고
    • OSHA work-practice guidelines for personnel dealing with cytotoxic (antineoplastic) drugs. Occupational Safety and Health Administration
    • OSHA
    • OSHA (1986) OSHA work-practice guidelines for personnel dealing with cytotoxic (antineoplastic) drugs. Occupational Safety and Health Administration. Am. J. Hosp. Pharm., 43, 1193-1204.
    • (1986) Am. J. Hosp. Pharm. , vol.43 , pp. 1193-1204
  • 79
    • 0025317639 scopus 로고
    • ASHP (American Society of Hospital Pharmacists) technical assistance bulletin on handling cytotoxic and hazardous drugs
    • ASHP
    • ASHP (1990) ASHP (American Society of Hospital Pharmacists) technical assistance bulletin on handling cytotoxic and hazardous drugs. Am. J. Hosp. Pharm, 47, 1033-1049.
    • (1990) Am. J. Hosp. Pharm , vol.47 , pp. 1033-1049
  • 80
    • 0029973067 scopus 로고    scopus 로고
    • Controlling occupational exposure to hazardous drugs. Occupational Safety and Health Administration
    • OSHA
    • OSHA (1996) Controlling occupational exposure to hazardous drugs. Occupational Safety and Health Administration. Am. J. Health Syst. Pharm., 53, 1669-1685.
    • (1996) Am. J. Health Syst. Pharm. , vol.53 , pp. 1669-1685
  • 81
    • 79955441624 scopus 로고    scopus 로고
    • OSHA Occupational Safety and Health Administration, US Department of Labor, Washington, DC, USA
    • OSHA (2000) OSHA Technical Manual. Hospital Investigations: Health Hazard-Section VI. Occupational Safety and Health Administration, US Department of Labor, Washington, DC, USA.
    • (2000) OSHA Technical Manual. Hospital Investigations: Health Hazard-Section VI
  • 83
    • 33747042154 scopus 로고    scopus 로고
    • NIOSH Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Washington, DC, USA
    • NIOSH (2004) NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings. Department of Health and Human Services, Centers for Disease Control and Prevention. National Institute for Occupational Safety and Health, Washington, DC, USA.
    • (2004) NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings
  • 84
    • 85016097523 scopus 로고    scopus 로고
    • ASHP (American Society of Hospital Pharmacists) guidelines on handling hazardous drugs
    • ASHP
    • ASHP (2006) ASHP (American Society of Hospital Pharmacists) guidelines on handling hazardous drugs. Am. J. Hosp. Pharm., 63, 1172-1193.
    • (2006) Am. J. Hosp. Pharm. , vol.63 , pp. 1172-1193
  • 85
    • 0033790136 scopus 로고    scopus 로고
    • The comet assay as a rapid test in biomonitoring occupational exposure to DNAdamaging agents and effect of confounding factors
    • Moller, P., Knudsen, L. E., Loft, S. and Wallin, H. (2000) The comet assay as a rapid test in biomonitoring occupational exposure to DNAdamaging agents and effect of confounding factors. Cancer Epidemiol. Biomarkers Prev., 9, 1005-1015.
    • (2000) Cancer Epidemiol. Biomarkers Prev. , vol.9 , pp. 1005-1015
    • Moller, P.1    Knudsen, L.E.2    Loft, S.3    Wallin, H.4
  • 87
    • 0344801351 scopus 로고    scopus 로고
    • An investigation of bone marrow and testicular cells in vivo using the comet assay
    • PII S0165121896000614
    • Anderson, D., Dhawan, A., Yu, T. W. and Plewa, M. J. (1996) An investigation of bone marrow and testicular cells in vivo using the comet assay. Mutat. Res., 370, 159-174. (Pubitemid 26365154)
    • (1996) Mutation Research - Genetic Toxicology , vol.370 , Issue.3-4 , pp. 159-174
    • Anderson, D.1    Dhawan, A.2    Yu, T.-W.3    Plewa, M.J.4
  • 88
    • 0028884765 scopus 로고
    • Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent
    • Olive, P. L. and Banath, J. P. (1995) Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp. Cell Res., 221, 19-26.
    • (1995) Exp. Cell Res. , vol.221 , pp. 19-26
    • Olive, P.L.1    Banath, J.P.2
  • 90
    • 0036372576 scopus 로고    scopus 로고
    • Occupational exposure to cytotoxic drugs in two UK oncology wards
    • DOI 10.1136/oem.59.9.608
    • Ziegler, E., Mason, H. J. and Baxter, P. J. (2002) Occupational exposure to cytotoxic drugs in two UK oncology wards. Occup. Environ. Med., 59, 608-612. (Pubitemid 34983587)
    • (2002) Occupational and Environmental Medicine , vol.59 , Issue.9 , pp. 608-612
    • Ziegler, E.1    Mason, H.J.2    Baxter, P.J.3
  • 93
    • 33845625637 scopus 로고    scopus 로고
    • Residual hazard assessment related to handling of antineoplastic drugs: Safety system evolution and quality assurance of analytical measurement
    • DOI 10.1196/annals.1371.047, Living in a Chemical World: Framing the Future in Light of the Past
    • Turci, R. and Minoia, C. (2006) Residual hazard assessment related to handling of antineoplastic drugs: safety system evolution and quality assurance of analytical measurement. Ann. N. Y. Acad. Sci., 1076, 649-656. (Pubitemid 44955296)
    • (2006) Annals of the New York Academy of Sciences , vol.1076 , pp. 649-656
    • Turci, R.1    Minoia, C.2
  • 94
    • 60249101744 scopus 로고    scopus 로고
    • Cyclophosphamide contamination observed on the external surfaces of drug vials and the efficacy of cleaning on vial contamination
    • Touzin, K., Bussieres, J. F., Langlois, E., Lefebvre, M. and Gallant, C. (2008) Cyclophosphamide contamination observed on the external surfaces of drug vials and the efficacy of cleaning on vial contamination. Ann. Occup. Hyg., 52, 765-771.
    • (2008) Ann. Occup. Hyg. , vol.52 , pp. 765-771
    • Touzin, K.1    Bussieres, J.F.2    Langlois, E.3    Lefebvre, M.4    Gallant, C.5
  • 95
    • 61749100798 scopus 로고    scopus 로고
    • Evaluation of surface contamination in a hospital hematology-oncology pharmacy
    • Touzin, K., Bussieres, J. F., Langlois, E. and Lefebvre, M. (2009) Evaluation of surface contamination in a hospital hematology-oncology pharmacy. J. Oncol. Pharm. Pract., 15, 53-61.
    • (2009) J. Oncol. Pharm. Pract. , vol.15 , pp. 53-61
    • Touzin, K.1    Bussieres, J.F.2    Langlois, E.3    Lefebvre, M.4
  • 96
    • 0021334333 scopus 로고
    • Occupational exposure to cyclophosphamide
    • Hirst, M., Tse, S., Mills, D. G., Levin, L. and White, D. F. (1984) Occupational exposure to cyclophosphamide. Lancet, 1, 186-188. (Pubitemid 14221990)
    • (1984) Lancet , vol.1 , Issue.8370 , pp. 186-188
    • Hirst, M.1    Tse, S.2    Mills, D.G.3
  • 97
    • 0021181902 scopus 로고
    • Assessment of potential exposure to antineoplastic agents in the health care setting
    • Stellman, J. M., Aufiero, B. M. and Taub, R. N. (1984) Assessment of potential exposure to antineoplastic agents in the health care setting. Preven. Med., 13, 245-255. (Pubitemid 14042054)
    • (1984) Preventive Medicine , vol.13 , Issue.3 , pp. 245-255
    • Stellman, J.M.1    Aufiero, B.M.2    Taub, R.N.3
  • 98
    • 33645739658 scopus 로고    scopus 로고
    • The alkaline comet assay: Towards validation in biomonitoring of DNA damaging exposures
    • Moller, P. (2006) The alkaline comet assay: towards validation in biomonitoring of DNA damaging exposures. Basic Clin. Pharmacol. Toxicol., 98, 336-345.
    • (2006) Basic Clin. Pharmacol. Toxicol. , vol.98 , pp. 336-345
    • Moller, P.1
  • 100
    • 62149133088 scopus 로고    scopus 로고
    • Environmental and occupational biomonitoring using the Comet assay
    • Valverde, M. and Rojas, E. (2009) Environmental and occupational biomonitoring using the Comet assay. Mutat. Res., 681, 93-109.
    • (2009) Mutat. Res. , vol.681 , pp. 93-109
    • Valverde, M.1    Rojas, E.2


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