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Volumn 14, Issue 5, 1999, Pages 497-503

Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: Analysis by alkaline single cell gel electrophoresis and cytogenetic methods

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; HYDROGEN PEROXIDE; MESYLIC ACID METHYL ESTER; MITOGENIC AGENT;

EID: 0032875309     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.5.497     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 0030987923 scopus 로고    scopus 로고
    • Detection of DNA damage in human lymphocytes by alkaline single cell gel electrophoresis after exposure to benzene or benzene metabolites
    • Andreoli, C., Leopardi, P. and Crebelli, R. (1997) Detection of DNA damage in human lymphocytes by alkaline single cell gel electrophoresis after exposure to benzene or benzene metabolites. Mutat. Res., 377, 95-104.
    • (1997) Mutat. Res. , vol.377 , pp. 95-104
    • Andreoli, C.1    Leopardi, P.2    Crebelli, R.3
  • 2
    • 0032927696 scopus 로고    scopus 로고
    • DNA damage by hydroquinone in human white blood cells: Analysis by alkaline single-cell gel electrophoresis
    • Andreoli, C., Rossi, S., Leopardi, P. and Crebelli, R. (1999) DNA damage by hydroquinone in human white blood cells: analysis by alkaline single-cell gel electrophoresis. Mutat. Res., 438, 37-45.
    • (1999) Mutat. Res. , vol.438 , pp. 37-45
    • Andreoli, C.1    Rossi, S.2    Leopardi, P.3    Crebelli, R.4
  • 3
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek, D.T. (1990) Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res., 231, 11-30.
    • (1990) Mutat. Res. , vol.231 , pp. 11-30
    • Beranek, D.T.1
  • 4
    • 0029095190 scopus 로고
    • Assessment of DNA damage in leukocytes from infected and malnourished children by single cell gel electrophoresis/comet assay
    • Betancourt, M., Ortiz, R., Gonzales, C., Perez, P., Corts, L., Rodriguez, L. and Villasenor, L. (1995) Assessment of DNA damage in leukocytes from infected and malnourished children by single cell gel electrophoresis/comet assay. Mutat. Res., 331, 65-77.
    • (1995) Mutat. Res. , vol.331 , pp. 65-77
    • Betancourt, M.1    Ortiz, R.2    Gonzales, C.3    Perez, P.4    Corts, L.5    Rodriguez, L.6    Villasenor, L.7
  • 5
    • 0029069893 scopus 로고
    • Comparative studies by comet test and sce analysis in human lymphocytes from 200 healthy subjects
    • Betti, C., Davini, T., Giannessi, L., Loprieno, N. and Barale, R. (1995) Comparative studies by comet test and SCE analysis in human lymphocytes from 200 healthy subjects. Mutat. Res., 343, 201-207.
    • (1995) Mutat. Res. , vol.343 , pp. 201-207
    • Betti, C.1    Davini, T.2    Giannessi, L.3    Loprieno, N.4    Barale, R.5
  • 7
    • 0027375157 scopus 로고
    • Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA
    • Collins, A.R., Duthie, S.J. and Dobson, V.L. (1993) Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis, 14, 1733-1735.
    • (1993) Carcinogenesis , vol.14 , pp. 1733-1735
    • Collins, A.R.1    Duthie, S.J.2    Dobson, V.L.3
  • 8
    • 0028833163 scopus 로고
    • The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells
    • Collins, A.R., Ai-guo, M. and Duthie, S.J. (1995) The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells. Mutat. Res., 336, 69-77.
    • (1995) Mutat. Res. , vol.336 , pp. 69-77
    • Collins, A.R.1    Ai-Guo, M.2    Duthie, S.J.3
  • 10
    • 2842526228 scopus 로고    scopus 로고
    • Detection of oxidised purines and UV-induced photoproducts in DNA of single cells, by inclusion of lesion-specific enzymes in the comet assay
    • Dusinska, M. and Collins, A. (1996) Detection of oxidised purines and UV-induced photoproducts in DNA of single cells, by inclusion of lesion-specific enzymes in the comet assay. ATLA Altern. Lab. Anim., 24, 405-411.
    • (1996) ATLA Altern. Lab. Anim. , vol.24 , pp. 405-411
    • Dusinska, M.1    Collins, A.2
  • 11
    • 0024461337 scopus 로고
    • Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody
    • Eastmond, D.A. and Tucker, J.D. (1989) Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ. Mol. Mutagen., 13, 34-43.
    • (1989) Environ. Mol. Mutagen. , vol.13 , pp. 34-43
    • Eastmond, D.A.1    Tucker, J.D.2
  • 12
  • 13
    • 0027497435 scopus 로고
    • The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations
    • Fenech, M. (1993) The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations. Mutat. Res., 285, 35-44.
    • (1993) Mutat. Res. , vol.285 , pp. 35-44
    • Fenech, M.1
  • 14
    • 0026593221 scopus 로고
    • Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes
    • Fenech, M. and Neville, S. (1992) Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen., 19, 27-36.
    • (1992) Environ. Mol. Mutagen. , vol.19 , pp. 27-36
    • Fenech, M.1    Neville, S.2
  • 15
    • 0025907152 scopus 로고
    • The mode of action of 1-β-D-arabinofuranosylcytosine in inhibiting DNA repair: New evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells
    • Gedik, C.M. and Collins, A.R. (1991) The mode of action of 1-β-D-arabinofuranosylcytosine in inhibiting DNA repair: new evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells. Mutat. Res., 254, 231-237.
    • (1991) Mutat. Res. , vol.254 , pp. 231-237
    • Gedik, C.M.1    Collins, A.R.2
  • 16
    • 0028147174 scopus 로고
    • Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells
    • Green, M.H.L., Lowe, J.E., Waugh, A.P.W., Aldridge, K.E., Cole, J. and Arlett, C.F. (1994) Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. Mutat. Res., 316, 91-102.
    • (1994) Mutat. Res. , vol.316 , pp. 91-102
    • Green, M.H.L.1    Lowe, J.E.2    Waugh, A.P.W.3    Aldridge, K.E.4    Cole, J.5    Arlett, C.F.6
  • 18
    • 0031015884 scopus 로고    scopus 로고
    • Alkaline single cell electrophoresis of DNA fragments in biomonitoring for genotoxicity: An introductory study on healthy human volunteers
    • Hellman, B., Vaghef, H., Friis, L. and Edling, C. (1997) Alkaline single cell electrophoresis of DNA fragments in biomonitoring for genotoxicity: an introductory study on healthy human volunteers. Int. Arch. Occup. Environ. Health, 69, 185-192.
    • (1997) Int. Arch. Occup. Environ. Health , vol.69 , pp. 185-192
    • Hellman, B.1    Vaghef, H.2    Friis, L.3    Edling, C.4
  • 20
    • 0022001993 scopus 로고
    • Dependency of the yield of sister-chromatid exchanges induced by alkylating agents on fixation time. Possible involvement of secondary lesions in sister chromatid exchange induction
    • Kaina, B. and Aurich, O. (1985) Dependency of the yield of sister-chromatid exchanges induced by alkylating agents on fixation time. Possible involvement of secondary lesions in sister chromatid exchange induction. Mutat. Res., 149, 451-461.
    • (1985) Mutat. Res. , vol.149 , pp. 451-461
    • Kaina, B.1    Aurich, O.2
  • 21
    • 0027340278 scopus 로고
    • 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations and gene mutations
    • 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations and gene mutations. Environ. Mol. Mutagen., 22, 283-292.
    • (1993) Environ. Mol. Mutagen. , vol.22 , pp. 283-292
    • Kaina, B.1    Fritz, G.2    Coquerelle, T.3
  • 22
    • 0023107254 scopus 로고
    • Effects of repair inhibition in the G1 phase of clastogen-treated human lymphocytes on the frequencies of chromosome-type and chromatid-type aberrations and sister-chromatid exchanges
    • Kishi, K. (1987) Effects of repair inhibition in the G1 phase of clastogen-treated human lymphocytes on the frequencies of chromosome-type and chromatid-type aberrations and sister-chromatid exchanges. Mutat. Res., 176, 105-116.
    • (1987) Mutat. Res. , vol.176 , pp. 105-116
    • Kishi, K.1
  • 23
    • 0020535194 scopus 로고
    • Cell kinetics and sister-chromatid exchange frequency in human lymphocytes
    • Lamberti, L., Bigatti-Ponzetto, P. and Ardito, G. (1983) Cell kinetics and sister-chromatid exchange frequency in human lymphocytes. Mutat. Res., 120, 193-199.
    • (1983) Mutat. Res. , vol.120 , pp. 193-199
    • Lamberti, L.1    Bigatti-Ponzetto, P.2    Ardito, G.3
  • 24
    • 0014360495 scopus 로고
    • Induction of DNA polymerase in human lymphocytes by phytohaemagglutinin
    • Loeb, L.A., Agarwal, S.S. and Woodside, M. (1968) Induction of DNA polymerase in human lymphocytes by phytohaemagglutinin. Proc. Natl Acad. Sci. USA, 61, 827-834.
    • (1968) Proc. Natl Acad. Sci. USA , vol.61 , pp. 827-834
    • Loeb, L.A.1    Agarwal, S.S.2    Woodside, M.3
  • 26
    • 0030725479 scopus 로고    scopus 로고
    • Detection of DNA lesions induced by chemical mutagens using the single-cell gel electrophoresis (comet) assay. 2. Relationship between DNA migration and alkaline condition
    • Miyamae, Y., Iwasaki, K., Kinae, N., Tsuda, S., Murakami, M., Tanaka, M. and Sasaki, Y.F. (1997) Detection of DNA lesions induced by chemical mutagens using the single-cell gel electrophoresis (Comet) assay. 2. Relationship between DNA migration and alkaline condition. Mutat. Res., 393, 107-113.
    • (1997) Mutat. Res. , vol.393 , pp. 107-113
    • Miyamae, Y.1    Iwasaki, K.2    Kinae, N.3    Tsuda, S.4    Murakami, M.5    Tanaka, M.6    Sasaki, Y.F.7
  • 27
    • 0023677076 scopus 로고
    • Functional consequences of the arabinosyl-cytosine structural lesion in DNA
    • Mikita, T. and Beardsley, G.P. (1988) Functional consequences of the arabinosyl-cytosine structural lesion in DNA. Biochemistry, 27, 4698-4705.
    • (1988) Biochemistry , vol.27 , pp. 4698-4705
    • Mikita, T.1    Beardsley, G.P.2
  • 29
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
    • Ostling, O. and Johanson, K.J. (1984) Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun., 123, 291-298.
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 291-298
    • Ostling, O.1    Johanson, K.J.2
  • 30
    • 0016328318 scopus 로고
    • New giemsa method for the differential staining of sister chromatids
    • Perry, P. and Wolff, S. (1974) New Giemsa method for the differential staining of sister chromatids. Nature (Lond.), 251, 156-158.
    • (1974) Nature (Lond.) , vol.251 , pp. 156-158
    • Perry, P.1    Wolff, S.2
  • 31
    • 0030012151 scopus 로고    scopus 로고
    • Detection of DNA-crosslinking agents with the alkaline comet assay
    • Pfuhler, S. and Wolf, H.U. (1996) Detection of DNA-crosslinking agents with the alkaline comet assay. Environ. Mol. Mutagen., 27, 196-201.
    • (1996) Environ. Mol. Mutagen. , vol.27 , pp. 196-201
    • Pfuhler, S.1    Wolf, H.U.2
  • 32
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N.P., McCoy, M.T., Tice, R.R. and Schneider, E.L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell, Res., 175, 184-191.
    • (1988) Exp. Cell, Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 33
    • 0030296410 scopus 로고    scopus 로고
    • Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis
    • Speit, G., Hanelt, S., Helbig, R., Seidel, A. and Hartmann, A. (1996) Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis. Toxicol. Lett., 88, 91-98.
    • (1996) Toxicol. Lett. , vol.88 , pp. 91-98
    • Speit, G.1    Hanelt, S.2    Helbig, R.3    Seidel, A.4    Hartmann, A.5
  • 34
    • 2642639542 scopus 로고    scopus 로고
    • Single cell gel electrophoresis assay: Sensitivity of peripheral white blood cells in human population studies
    • Sram, R.J., Podrazilova, K., Dejmek, J., Mrackova, G. and Pilcik, T. (1998) Single cell gel electrophoresis assay: sensitivity of peripheral white blood cells in human population studies. Mutagenesis, 13, 99-103.
    • (1998) Mutagenesis , vol.13 , pp. 99-103
    • Sram, R.J.1    Podrazilova, K.2    Dejmek, J.3    Mrackova, G.4    Pilcik, T.5
  • 35
    • 0025962780 scopus 로고
    • Non-random cell killing in cryopreservation: Implications for performance of the battery of leucocyte tests (BLT) I. Toxic and immunotoxic effects
    • Strauss, G.H.S. (1991) Non-random cell killing in cryopreservation: implications for performance of the battery of leucocyte tests (BLT) I. Toxic and immunotoxic effects. Mutat. Res., 252, 1-15.
    • (1991) Mutat. Res. , vol.252 , pp. 1-15
    • Strauss, G.H.S.1
  • 36
    • 0028907998 scopus 로고
    • The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair
    • Surralles, J., Xamena, N., Creus, A. and Marcos, R. (1995) The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair. Mutat. Res., 342, 43-59.
    • (1995) Mutat. Res. , vol.342 , pp. 43-59
    • Surralles, J.1    Xamena, N.2    Creus, A.3    Marcos, R.4
  • 37
    • 0030851297 scopus 로고    scopus 로고
    • Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: Genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide
    • Van Goethem, F., Lison, D. and Kirsch-Volders, M. (1997) Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat. Res., 392, 31-43.
    • (1997) Mutat. Res. , vol.392 , pp. 31-43
    • Van Goethem, F.1    Lison, D.2    Kirsch-Volders, M.3
  • 38
    • 0029032680 scopus 로고
    • 6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guanine phosphoribosyltransferase gene in T-lymphocytes
    • 6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guanine phosphoribosyltransferase gene in T-lymphocytes. Carcinogenesis, 16, 1473-1481.
    • (1995) Carcinogenesis , vol.16 , pp. 1473-1481
    • Vodicka, P.1    Bastlova, T.2    Vodickova, L.3    Peterkova, K.4    Lambert, B.5    Hemminki, K.6
  • 39
    • 0030822993 scopus 로고    scopus 로고
    • Comparison of alkaline single cell gel (Comet) and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens
    • Vrzoc, M. and Petras, M.L. (1997) Comparison of alkaline single cell gel (Comet) and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens. Mutat. Res., 381, 31-40.
    • (1997) Mutat. Res. , vol.381 , pp. 31-40
    • Vrzoc, M.1    Petras, M.L.2
  • 40
    • 0023908550 scopus 로고
    • Sister chromatid exchange and cell cycle patterns of normal human bone marrow cells after in vitro exposure to cytostatic drugs
    • Zhang, S., Huang, J., Chen, P. and U.C. (1988) Sister chromatid exchange and cell cycle patterns of normal human bone marrow cells after in vitro exposure to cytostatic drugs. Cancer Genet. Cytogenet., 31, 157-163.
    • (1988) Cancer Genet. Cytogenet. , vol.31 , pp. 157-163
    • Zhang, S.1    Huang, J.2    Chen, P.3


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