-
1
-
-
0023434038
-
Syndrome of the black swan
-
Harris E: Syndrome of the black swan. Br. J. Rheumatol. 26(5), 324-326 (1987).
-
(1987)
Br. J. Rheumatol.
, vol.26
, Issue.5
, pp. 324-326
-
-
Harris, E.1
-
2
-
-
0033512274
-
International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International Workshop
-
DOI 10.1002/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F
-
Wilson W, Gharavi A, Koike T et al.: International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome. Arthritis Rheum. 42(7), 1309-1311 (1999). (Pubitemid 30265586)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.7
, pp. 1309-1311
-
-
Wilson, W.A.1
Gharavi, A.E.2
Koike, T.3
Lockshin, M.D.4
Ware Branch, D.5
Piette, J.-C.6
Brey, R.7
Derksen, R.8
Nigel Harris, E.9
Hughes, G.R.V.10
Triplett, D.A.11
Khamashta, M.A.12
-
3
-
-
33344458573
-
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome APS
-
Miyakis S, Lockshin M, Atusmi T et al.: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).J. Thromb. Haemost. 4, 295-306 (2006).
-
(2006)
J. Thromb. Haemost.
, vol.4
, pp. 295-306
-
-
Miyakis, S.1
Lockshin, M.2
Atusmi, T.3
-
4
-
-
0023772539
-
Antiprothrombin antibodies and the lupus anticoagulant
-
Fleck R, Rapaport S, Rao L: Antiprothrombin antibodies and the lupus anticoagulant. Blood 72(2), 512-519 (1988).
-
(1988)
Blood
, vol.72
, Issue.2
, pp. 512-519
-
-
Fleck, R.1
Rapaport, S.2
Rao, L.3
-
5
-
-
0025332717
-
Antiphospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I apolipoprotein H
-
USA
-
McNeil H, Simpson R, Chesterman C, Krilis S: Antiphospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H).Proc. Natl Acad. Sci. USA 87, 4120-4124 (1990).
-
(1990)
Proc. Natl Acad. Sci.
, vol.87
, pp. 4120-4124
-
-
McNeil, H.1
Simpson, R.2
Chesterman, C.3
Krilis, S.4
-
6
-
-
33748550680
-
2-glycoprotein I: Prevalence, clinical correlations, and importance of persistent positivity in patients with antiphospholipid syndrome and systemic lupus erythematosus
-
Danowski A, Kickler T, Petri M: Anti-β2-glycoprotein I: prevalence, clinical correlations, and importance of persistent positivity in patients with antiphospholipid syndrome and systemic lupus erythematosus. J. Rheumatol. 33(9), 1775-1779 (2006). (Pubitemid 44373210)
-
(2006)
Journal of Rheumatology
, vol.33
, Issue.9
, pp. 1775-1779
-
-
Danowski, A.1
Kickler, T.S.2
Petri, M.3
-
7
-
-
34248523994
-
2-glycoprotein I and the homologous catalytic domains of several serine proteases
-
DOI 10.1002/art.22522
-
Lin W-S, Chen P-C, Yang C-D et al.: Some antiphospholipid antibodies recognize conformational epitopes shared by β2-glycoprotein I and the homologous catalytic domains of several serine proteases. Arthritis Rheum. 56(5), 1638-1647 (2007). (Pubitemid 46764093)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.5
, pp. 1638-1647
-
-
Lin, W.-S.1
Chen, P.-C.2
Yang, C.-B.3
Cho, E.4
Hahn, B.H.5
Grossman, J.6
Hwang, K.-K.7
Chen, P.P.8
-
8
-
-
61449186513
-
Risk factors for a first thrombotic event in antiphospholipid antibody carriers a multicentre retrospective follow-up study
-
Ruffatti A, Del Ross T, Ciprian M et al.: Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up study. Ann. Rheum. Dis. 68, 397-399 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 397-399
-
-
Ruffatti, A.1
Del Ross, T.2
Ciprian, M.3
-
9
-
-
67149087369
-
Determinants of risk for venous and arterial thrombosis in primary antiphospholipid syndrome and in antiphospholipid syndrome with systemic lupus erythematosus
-
Danowski A, de Azevedo M, de Souza Papi J, Petri M: Determinants of risk for venous and arterial thrombosis in primary antiphospholipid syndrome and in antiphospholipid syndrome with systemic lupus erythematosus. J. Rheumatol. 36, 1195-1199 (2009).
-
(2009)
J. Rheumatol.
, vol.36
, pp. 1195-1199
-
-
Danowski, A.1
De Azevedo, M.2
De Souza Papi, J.3
Petri, M.4
-
10
-
-
0037370733
-
Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: A systematic review of the literature
-
DOI 10.1182/blood-2002-02-0441
-
Galli M, Luciani D, Bertolini G, Barbui T: Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 101(5), 1827-1832 (2003). (Pubitemid 36237580)
-
(2003)
Blood
, vol.101
, Issue.5
, pp. 1827-1832
-
-
Galli, M.1
Luciani, D.2
Bertolini, G.3
Barbui, T.4
-
11
-
-
30644461619
-
Lupus anticoagulants and the risk of a first episode of deep venous thrombosis
-
DOI 10.1111/j.1538-7836.2005.01485.x
-
De Groot P, Lutters B, Derksen R, Lisman T, Maijers J, Rosendaal F: Lupus anticoagulants and the risk of a first episode of deep venous thrombosis. J. Thromb. Haemost. 3, 1993-1997 (2005). (Pubitemid 43086056)
-
(2005)
Journal of Thrombosis and Haemostasis
, vol.3
, Issue.9
, pp. 1993-1997
-
-
De Groot, P.G.1
Lutters, B.2
Derksen, R.H.W.M.3
Lisman, T.4
Meijers, J.C.M.5
Rosendaal, F.R.6
-
12
-
-
67649371944
-
Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: A multicentre prospective study of 1000 patients
-
Cervera R, Khamashta M, Shoenfeld Y et al.: Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: a multicentre prospective study of 1000 patients. Ann. Rheum. Dis. 68, 1428-1432 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1428-1432
-
-
Cervera, R.1
Khamashta, M.2
Shoenfeld, Y.3
-
13
-
-
33746993589
-
Mortality in the catastrophic antiphospholipid syndrome: Causes of death and prognostic factors in a series of 250 patients
-
DOI 10.1002/art.22018
-
Bucciarelli S, Espinosa G, Cervera R et al.: Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum. 54(8), 2568-2576 (2006). (Pubitemid 44205018)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.8
, pp. 2568-2576
-
-
Bucciarelli, S.1
Espinosa, G.2
Cervera, R.3
Erkan, D.4
Gomez-Puerta, J.A.5
Ramos-Casals, M.6
Font, J.7
Asherson, R.A.8
-
14
-
-
33344456904
-
2-glycoprotein I only after a conformational change
-
DOI 10.1182/blood-2005-05-1943
-
de Laat B, Derksen R, Lummel M, Pennings M, de Groot P: Pathogenic anti-β2-glycoprotein I antibodies recognize domain I of the β2-glycoprotein I only after a conformational change. Blood 107, 1916-1924 (2006). (Pubitemid 43289372)
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 1916-1924
-
-
De Laat, B.1
Derksen, R.H.W.M.2
Van Lummel, M.3
Pennings, M.T.T.4
De Groot, P.G.5
-
15
-
-
13544276197
-
2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
-
DOI 10.1182/blood-2004-09-3387
-
de Laat B, Derksen R, Urbanus R, de Groot P: IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis. Blood 105, 1540-1545 (2005). (Pubitemid 40223671)
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1540-1545
-
-
De Laat, B.1
Derksen, R.H.W.M.2
Urbanus, R.T.3
De Groot, P.G.4
-
16
-
-
33846236309
-
Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2-glycoprotein I
-
Ioannou Y, Pericleous C, Giles I, Latchman D, Isenberg D, Rahman A: Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2-glycoprotein I. Arthritis Rheum. 56(1), 280-290 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, Issue.1
, pp. 280-290
-
-
Ioannou, Y.1
Pericleous, C.2
Giles, I.3
Latchman, D.4
Isenberg, D.5
Rahman, A.6
-
17
-
-
77956488547
-
β2-Glycoprotein I can exist in 2 conformations: Implications for our understanding of the antiphospholipid syndrome
-
Agar C, van Os G, Morgelin M et al.: β2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood 116, 1336-1343 (2010).
-
(2010)
Blood
, vol.116
, pp. 1336-1343
-
-
Agar, C.1
Van Os, G.2
Morgelin, M.3
-
18
-
-
5444256422
-
Beta-2-glycoprotein specificity of human anti-phospholipid antibody resides on the light chain: A novel mechanism for acquisition of cross-reactivity by an autoantibody
-
DOI 10.1016/j.molimm.2004.07.012, PII S0161589004002743
-
Kumar S, Nagl S, Kalsi J et al.: b-2-glycoprotein specificity of human anti-phospholipid antibody resides on the light chain: a novel mechanism for acquisitionof cross-reactivity by an autoantibody. Mol. Immunol. 42, 39-48 (2004). (Pubitemid 39360925)
-
(2005)
Molecular Immunology
, vol.42
, Issue.1
, pp. 39-48
-
-
Kumar, S.1
Nagl, S.2
Kalsi, J.K.3
Ravirajan, C.T.4
Athwal, D.5
Latchman, D.S.6
Pearl, L.H.7
Isenberg, D.A.8
-
19
-
-
0033173789
-
247 polymorphism and anti-β2-glycoprotein I antibodies in patients with primary antiphospholipid syndrome
-
DOI 10.1093/rheumatology/38.8.721
-
Atsumi T, Tsutsumi A, Amengual O et al.: Correlation between β2-glycoprotein I valine/ leucine 247 polymorphism and anti-β2- glycoprotein I antibodies in patients with primary antiphospholipid syndrome. Rheumatology 38(8), 721-723 (1999). (Pubitemid 29507387)
-
(1999)
Rheumatology
, vol.38
, Issue.8
, pp. 721-723
-
-
Atsumi, T.1
Tsutsumi, A.2
Amengual, O.3
Khamashta, M.A.4
Hughes, G.R.V.5
Miyoshi, Y.6
Ichikawa, K.7
Koike, T.8
-
20
-
-
12344312949
-
Significance of valine leucine 247polymorphism of β2-glycoprotein I in antiphospholipid syndrome: Increased reactivity of anti-β2-glycoprotein I autoantibodies to the valine 247 β2- glycoprotein I variant
-
Yasuda S, Atusmi T, Matsuura E et al.: Significance of valine/leucine 247polymorphism of β2- glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-β2-glycoprotein I autoantibodies to the valine 247 β2- glycoprotein I variant. Arthritis Rheum. 52(1), 212-218 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, Issue.1
, pp. 212-218
-
-
Yasuda, S.1
Atusmi, T.2
Matsuura, E.3
-
21
-
-
0033496362
-
2-glycoprotein I antibodies in the antiphospholipid syndrome
-
DOI 10.1002/1529-0131(199908)42:8<1655::AID-ANR14>3.0.CO;2-B
-
Hirose N, Williams R, Alberts A et al.: A role for the polymorphism at position 247 of the β2-glycoprotein I gene in the generation of anti-β2-glycoprotein I antibodies in the antiphospholipid syndrome. Arthritis Rheum. 42(8), 1655-1661 (1999). (Pubitemid 30263634)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.8
, pp. 1655-1661
-
-
Hirose, N.1
Williams, R.2
Alberts, A.R.3
Furie, R.A.4
Chartash, E.K.5
Jain, R.I.6
Sison, C.7
Lahita, R.G.8
Merrill, J.T.9
Cucurull, E.10
Gharavi, A.E.11
Sammaritano, L.R.12
Salmon, J.E.13
Hashimoto, S.14
Sawada, T.15
Chu, C.C.16
Gregersen, P.K.17
Chiorazzi, N.18
-
22
-
-
69949179178
-
Val Leu247 polymorphism of β2-glycoprotein I in brazilian patients with antiphospholipid syndrome -a genetic risk factor
-
Pernambuco-Climaco J, Brochado M, Frietas M, Roselino A, Louzado-Junior P: Val/ Leu247 polymorphism of β2-glycoprotein I in Brazilian patients with antiphospholipid syndrome - a genetic risk factor? Ann. NY Acad. Sci. 1173, 509-514 (2009).
-
(2009)
Ann. NY Acad. Sci.
, vol.1173
, pp. 509-514
-
-
Pernambuco-Climaco, J.1
Brochado, M.2
Frietas, M.3
Roselino, A.4
Louzado-Junior, P.5
-
23
-
-
70449390005
-
The association between circulating antibodies against domain I of β2- glycoprotein I and thrombosis: An international multicenter study
-
de Laat B, Pengo V, Pabinger I et al.: The association between circulating antibodies against domain I of β2- glycoprotein I and thrombosis: an international multicenter study. J. Thromb. Haemost. 7, 1767-1773 (2009).
-
(2009)
J. Thromb. Haemost.
, vol.7
, pp. 1767-1773
-
-
De Laat, B.1
Pengo, V.2
Pabinger, I.3
-
24
-
-
33847055815
-
β2-glycoprotein I binds thrombin via exosite I and exosite II: anti-β2-glycoprotein I antibodies potentiate the inhibitory effect of β2-glycoprotein I on thrombin-mediated factor XIa generation
-
Rahgozar S, Yang Q, Giannakopoulos B, Yan X, Miyakis S, Krilis S: β2-glycoprotein I binds thrombin via exosite I and exosite II: anti-β2-glycoprotein I antibodies potentiate the inhibitory effect of β2-glycoprotein I on thrombin-mediated factor XIa generation. Arthritis Rheum. 56(2), 605-613 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, Issue.2
, pp. 605-613
-
-
Rahgozar, S.1
Yang, Q.2
Giannakopoulos, B.3
Yan, X.4
Miyakis, S.5
Krilis, S.6
-
25
-
-
42449145853
-
2-glycoprotein I autoantibodies
-
DOI 10.1002/art.23387
-
Rahgozar S, Giannakopoulos B, Yan X et al.: β2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: potentiation of this effect in the presence of anti-β2- glycoprotein I autoantibodies. Arthritis Rheum. 58, 1146-1155 (2008). (Pubitemid 351564018)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.4
, pp. 1146-1155
-
-
Rahgozar, S.1
Giannakopoulos, B.2
Yan, X.3
Wei, J.4
Jian, C.Q.5
Gemmell, R.6
Krilis, S.A.7
-
26
-
-
27744494859
-
2-glycoprotein I for ApoER2β on platelets is located is in domain V
-
DOI 10.1074/jbc.M504172200
-
van Lummel M, Pennings M, Derksen R et al.: The binding site in β2-glycoprotein I for ApoER2́ on platelets is located in domain V. J. Biol. Chem. 280(44), 36729-36736 (2005). (Pubitemid 41587752)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 36729-36736
-
-
Van Lummel, M.1
Pennings, M.T.T.2
Derksen, R.H.W.M.3
Urbanus, R.T.4
Lutters, B.C.H.5
Kaldenhoven, N.6
De Groot, P.G.7
-
27
-
-
34250757023
-
Platelets express three different splice variants of ApoER2 that are all involved in signaling
-
DOI 10.1111/j.1538-7836.2007.02605.x
-
Pennings M, Derksen R, Urbanus R, Tekelenburg W, Hemrika W, de Groot P: Platelets express three different splice variants of ApoER2 that are all involved in signaling. J. Thromb. Haemost. 5, 1538-1544 (2007). (Pubitemid 46965385)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.7
, pp. 1538-1544
-
-
Pennings, M.T.T.1
Derksen, R.H.W.M.2
Urbanus, R.T.3
Tekelenburg, W.L.4
Hemrika, W.5
De Groot, P.G.6
-
28
-
-
0141445991
-
2-Glycoprotein I Increase Platelet Deposition to Collagen via Interaction with Phospholipids and the Apolipoprotein E Receptor 2β
-
DOI 10.1074/jbc.M212655200
-
Lutters B, Derksen R, Tekelenburg W, Lenting P, Arnout J, de Groot P: Dimers of β2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2́. J. Biol. Chem. 278(36), 33831-33838 (2003). (Pubitemid 37553217)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 33831-33838
-
-
Lutters, B.C.H.1
Derksen, R.H.W.M.2
Tekelenburg, W.L.3
Lenting, P.J.4
Arnout, J.5
De Groot, P.G.6
-
29
-
-
79251578627
-
Apolipoprotein E receptor 2́ is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
-
Romay-Penabad Z, Aguilar-Valenzuela R, Urbanus R et al.: Apolipoprotein E receptor 2́ is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome. Blood 117(4), 1408-1414 (2011).
-
(2011)
Blood
, vol.117
, Issue.4
, pp. 1408-1414
-
-
Romay-Penabad, Z.1
Aguilar-Valenzuela, R.2
Urbanus, R.3
-
30
-
-
46749138272
-
Anti-annexin II antibodies in systemic autoimmune disease and antiphospholipid syndrome
-
Salle V, Maziere J, Smail A et al.: Anti-annexin II antibodies in systemic autoimmune disease and antiphospholipid syndrome. J. Clin. Immunol. 28, 291-297 (2008).
-
(2008)
J. Clin. Immunol.
, vol.28
, pp. 291-297
-
-
Salle, V.1
Maziere, J.2
Smail, A.3
-
31
-
-
70350786142
-
Annexin A2 mediates anti-b2GPI b2GPI-induced tissue factor expression on monocytes
-
Zhou H, Wang H, Li N et al.: Annexin A2 mediates anti-b2GPI/b2GPI-induced tissue factor expression on monocytes. Int. J. Mol. Med. (24), 557-562 (2009).
-
(2009)
Int. J. Mol. Med.
, vol.24
, pp. 557-562
-
-
Zhou, H.1
Wang, H.2
Li, N.3
-
32
-
-
0028129557
-
An endothelial cell receptor for plasminogen tissue plasminogen activator t-PA
-
Cesarman G, Guevara C, Hajjar K: An endothelial cell receptor for plasminogen/ tissue plasminogen activator (t-PA).J. Biol. Chem. 269(33), 21198-21203 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.33
, pp. 21198-21203
-
-
Cesarman, G.1
Guevara, C.2
Hajjar, K.3
-
33
-
-
0034685886
-
2-glycoprotein I to human endothelial cells is mediated by annexin II
-
DOI 10.1074/jbc.275.20.15541
-
Ma K, Simantov R, Zhang J-C, Silverstein R, Hajjar K, McCrae K: High affinity binding of β2-glycoprotein I to human endothelial cells is mediated by annexin II. J. Biol. Chem. 275(20), 15541-15548 (2000). (Pubitemid 30337288)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.20
, pp. 15541-15548
-
-
Ma, K.1
Simantov, R.2
Zhang, J.-C.3
Silverstein, R.4
Hajjar, K.A.5
McCrae, K.R.6
-
34
-
-
70449509134
-
Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
-
Romay-Penabad Z, Montiel-Manzano M, Shilagard T et al.: Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood 114, 3074-3083 (2009).
-
(2009)
Blood
, vol.114
, pp. 3074-3083
-
-
Romay-Penabad, Z.1
Montiel-Manzano, M.2
Shilagard, T.3
-
35
-
-
50349088997
-
Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10 p11
-
He K, Deora A, Xiong H et al.: Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. J. Biol. Chem. 283(28), 19192-19200 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.28
, pp. 19192-19200
-
-
He, K.1
Deora, A.2
Xiong, H.3
-
36
-
-
14944367961
-
2 glycoprotein I antibodies
-
DOI 10.1182/blood-2004-05-1708
-
Zhang J, McCrae K: Annexin A2 mediates endothelial cell activation by antiphospholipid/anti-β-2 glycoprotein I antibodies. Blood 105, 1964-1969 (2005). (Pubitemid 40731779)
-
(2005)
Blood
, vol.105
, Issue.5
, pp. 1964-1969
-
-
Zhang, J.1
McCrae, K.R.2
-
37
-
-
77953624768
-
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signalling pathways
-
Lambrianides A, Carroll C, Pierangeli S et al.: Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signalling pathways. J. Immunol. 184, 6622-6628 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 6622-6628
-
-
Lambrianides, A.1
Carroll, C.2
Pierangeli, S.3
-
38
-
-
33846899419
-
The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
-
DOI 10.1182/blood-2005-03-024463
-
Satta N, Dunoyer-Geindre S, Reber G et al.: The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood 109, 1507-1514 (2007). (Pubitemid 46239583)
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1507-1514
-
-
Satta, N.1
Dunoyer-Geindre, S.2
Reber, G.3
Fish, R.J.4
Boehlen, F.5
Kruithof, E.K.O.6
De Moerloose, P.7
-
39
-
-
33744481250
-
Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
-
DOI 10.1182/blood-2005-07-2636
-
Cesarman-Maus G, Rios-Luna N, Deora A et al.: Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome. Blood 107, 4375-4382 (2006). (Pubitemid 43801363)
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4375-4382
-
-
Cesarman-Maus, G.1
Rios-Luna, N.P.2
Deora, A.B.3
Huang, B.4
Villa, R.5
Cravioto, M.D.C.6
Alarcon-Segovia, D.7
Sanchez-Guerrero, J.8
Hajjar, K.A.9
-
40
-
-
69649095448
-
β2-Glycoprotein I and annexin A5 phospholipid interactions: Artificial and cell membranes
-
Frank M, Sodin-Semri S, Irman S, Bozic B, Rozman B: β2-glycoprotein I and annexin A5 phospholipid interactions: artificial and cell membranes. Autoimmun. Rev. 9, 5-10 (2009).
-
(2009)
Autoimmun. Rev.
, vol.9
, pp. 5-10
-
-
Frank, M.1
Sodin-Semri, S.2
Irman, S.3
Bozic, B.4
Rozman, B.5
-
41
-
-
7244242660
-
Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: A pathway to targeted therapies
-
DOI 10.1016/j.thromres.2004.06.031, PII S0049384804003408
-
Pierangeli S, Vega-Ostertag M, Harris E: Intracellular signaling triggerd by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. Thromb. Res. 114, 467-476 (2004). (Pubitemid 39429425)
-
(2004)
Thrombosis Research
, vol.114
, Issue.5-6 SPEC. ISS.
, pp. 467-476
-
-
Pierangeli, S.S.1
Vega-Ostertag, M.2
Nigel Harris, E.3
-
42
-
-
33644868952
-
Resistance to annexin A5 binding and anticoagulant activity in plasmas from patients with the antiphospholipid syndrome but not with syphilis
-
Wu X, Pierangeli S, Rand J: Resistance to annexin A5 binding and anticoagulant activity in plasmas from patients with the antiphospholipid syndrome but not with syphilis. J. Thromb. Haemost. 4, 271-273 (2006).
-
(2006)
J. Thromb. Haemost.
, vol.4
, pp. 271-273
-
-
Wu, X.1
Pierangeli, S.2
Rand, J.3
-
43
-
-
33846936761
-
Correlation between antiphospholipid antibodies that recognize domain I of β2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5
-
DOI 10.1182/blood-2006-07-030148
-
de Laat B, Wu X, van Lummel M, Derksen R, de Groot P, Rand J: Correlation between antiphospholipid antibodies that recognize domain I of β2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5. Blood 109, 1490-1494 (2007). (Pubitemid 46239580)
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1490-1494
-
-
De Laat, B.1
Wu, X.-X.2
Van Lummel, M.3
Derksen, R.H.W.M.4
De Groot, P.G.5
Rand, J.H.6
-
44
-
-
77950435764
-
Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: Evidence for a novel effect for an old anitmalarial drug
-
Rand J, Wu X, Quinn A et al.: Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old anitmalarial drug. Blood 115, 2292-2299 (2010).
-
(2010)
Blood
, vol.115
, pp. 2292-2299
-
-
Rand, J.1
Wu, X.2
Quinn, A.3
-
45
-
-
48749104624
-
Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-β2-glycoprotein I complexes to phospholipid bilayers
-
Rand J, Wu X, Quinn A, Chen P, Hathcock J, Taatjes D: Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-β2-glycoprotein I complexes to phospholipid bilayers. Blood 112, 1687-1695 (2008).
-
(2008)
Blood
, vol.112
, pp. 1687-1695
-
-
Rand, J.1
Wu, X.2
Quinn, A.3
Chen, P.4
Hathcock, J.5
Taatjes, D.6
-
46
-
-
51849152401
-
Proteomic analysis in monocytes of antiphospholipid syndrome patients: Deregulation of proteins related to the development of thrombosis
-
Lopez-Pedrera C, Cuadrado M, Hernandez V et al.: Proteomic analysis in monocytes of antiphospholipid syndrome patients: deregulation of proteins related to the development of thrombosis. Arthritis Rheum. 58(9), 2835-2844 (2006).
-
(2006)
Arthritis Rheum.
, vol.58
, Issue.9
, pp. 2835-2844
-
-
Lopez-Pedrera, C.1
Cuadrado, M.2
Hernandez, V.3
-
47
-
-
31044449865
-
Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway
-
DOI 10.1002/art.21549
-
Lopez-Pedrera C, Buendia P, Cuadrado M et al.: Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kB/Rel proteins via the p38 mitogenactivated protein kinase pathway, and of the MEK-1/ERK pathway. Arthritis Rheum. 54(1), 301-311 (2006). (Pubitemid 43122214)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.1
, pp. 301-311
-
-
Lopez-Pedrera, C.1
Buendia, P.2
Cuadrado, M.J.3
Siendones, E.4
Aguirre, M.A.5
Barbarroja, N.6
Montiel-Duarte, C.7
Torres, A.8
Khamashta, M.9
Velasco, F.10
-
48
-
-
34548079756
-
Role of p38 mitogen-activated protein kinase in antiphospholipid antibody-mediated thrombosis and endothelial cell activation
-
DOI 10.1111/j.1538-7836.2007.02680.x
-
Vega-Ostertag M, Ferrara D, Romay-Penabad Z et al.: Role of p38 mitogen-activated protein kinase in antiphospholipid antibody-mediated thrombosis and endothelial cell activation. J. Thromb. Haemost. 5, 1828-1834 (2007). (Pubitemid 47288938)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.9
, pp. 1828-1834
-
-
Vega-Ostertag, M.E.1
Ferrara, D.E.2
Romay-Penabad, Z.3
Liu, X.4
Taylor, W.R.5
Colden-Stanfield, M.6
Pierangeli, S.S.7
-
49
-
-
8344267910
-
2Glycoprotein I antibodies
-
DOI 10.1093/intimm/dxh166
-
Bohgaki M, Atsumi T, Yamashita Y et al.: The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-b2glycoprotein I antibodies. Int. Immunol. 16(1), 1633-1641 (2004). (Pubitemid 39480782)
-
(2004)
International Immunology
, vol.16
, Issue.11
, pp. 1633-1641
-
-
Bohgaki, M.1
Atsumi, T.2
Yamashita, Y.3
Yasuda, S.4
Sakai, Y.5
Furusaki, A.6
Bohgaki, T.7
Amengual, O.8
Amasaki, Y.9
Koike, T.10
-
50
-
-
33750091036
-
Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome
-
DOI 10.1111/j.1538-7836.2006.02193.x
-
Cuadrado M, Buendia P, Velasco F et al.: Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome. J. Thromb. Haemost. 4, 2461-2469 (2006). (Pubitemid 44575442)
-
(2006)
Journal of Thrombosis and Haemostasis
, vol.4
, Issue.11
, pp. 2461-2469
-
-
Cuadrado, M.J.1
Buendia, P.2
Velasco, F.3
Aguirre, M.A.4
Barbarroja, N.5
Torres, L.A.6
Khamashta, M.7
Lopez-Pedrera, C.8
-
51
-
-
77649099693
-
Differential expression of proteaseactivated receptors in monocytes from patients with primary antiphospholipid syndrome
-
Lopez-Pedrera C, Aguirre M, Buendia P et al.: Differential expression of proteaseactivated receptors in monocytes from patients with primary antiphospholipid syndrome. Arthritis Rheum. 62, 869-877 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 869-877
-
-
Lopez-Pedrera, C.1
Aguirre, M.2
Buendia, P.3
-
52
-
-
37749045374
-
Platelet activation rather than endothelial injury identifies risk of thrombosis in subjects positive for antiphospholipid antibodies
-
Jy W, Tiede M, Bidot C et al.: Platelet activation rather than endothelial injury identifies risk of thrombosis in subjects positive for antiphospholipid antibodies. Thromb. Res. 121, 319-325 (2007).
-
(2007)
Thromb. Res.
, vol.121
, pp. 319-325
-
-
Jy, W.1
Tiede, M.2
Bidot, C.3
-
53
-
-
45149103015
-
Double heterozygosity polymorphisms for platelet glycoproteins Ia/IIa and IIb/IIIa increases arterial thrombosis and arteriosclerosis in patients with the antiphospholipid syndrome or with systemic lupus erythematosus
-
DOI 10.1136/ard.2007.077321
-
Jimenez S, Tassies D, Espinosa G et al.: Double heterozygosity polymorphisms for platelet glycoproteins Ia/IIa and IIb/IIIa increases arterial thrombosis and arteriosclerosis in patients with antiphospholipid syndrome or with systemic lupus erythematosus. Ann. Rheum. Dis. 67, 835-840 (2008). (Pubitemid 351829385)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.6
, pp. 835-840
-
-
Jimenez, S.1
Tassies, D.2
Espinosa, G.3
Garcia-Criado, A.4
Plaza, J.5
Monteagudo, J.6
Cervera, R.7
Reverter, J.C.8
-
54
-
-
47649130477
-
2-glycoprotein I requires signaling via both glycoprotein Ibα and apolipoprotein E receptor 2β
-
DOI 10.1111/j.1538-7836.2008.03021.x
-
Urbanus R, Pennings M, Derksen R, de Groot P: Platelet activation by dimeric β2-glycoprotein I requires signaling via both glycoprotein Iba and apolipoprotein E receptor 2́. J. Thromb. Haemost. 6, 1405-1412 (2008). (Pubitemid 352016322)
-
(2008)
Journal of Thrombosis and Haemostasis
, vol.6
, Issue.8
, pp. 1405-1412
-
-
Urbanus, R.T.1
Pennings, M.T.T.2
Derksen, R.H.W.M.3
De Groot, P.G.4
-
55
-
-
39549086338
-
Anti-heparin platelet factor 4 antibodies in systemic lupus erythaematosus are associated with IgM antiphospholipid antibodies and the antiphospholipid syndrome
-
DOI 10.1136/ard.2007.074476
-
Alpert D, Mandl L, Erkan D, Yin W, Peerschke W, Salmon J: Anti-heparin platelet factor 4 antibodies in systemic lupus erythaematosus are associated with IgM antiphospholipid antibodies and the antiphospholipid syndrome. Ann. Rheum. Dis. 67, 395-401 (2008). (Pubitemid 351281277)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.3
, pp. 395-401
-
-
Alpert, D.1
Mandl, L.A.2
Erkan, D.3
Yin, W.4
Peerschke, E.I.5
Salmon, J.E.6
-
56
-
-
33847371134
-
High prevalence of antibodies to platelet factor 4 heparin in patients with antiphospholipid antibodies in absence of heparin-induced thrombocytopenia
-
DOI 10.1177/0961203306075562
-
Martin-Toutain I, Piette J, Diemert M, Faucher C, Jobic L, Ankri A: High prevalence of antibodies to platelet factor 4 heparin in patients with antiphospholipid syndrome in absence of heparin-induced thrombocytopenia. Lupus 16, 79-83 (2007). (Pubitemid 46347928)
-
(2007)
Lupus
, vol.16
, Issue.2
, pp. 79-83
-
-
Martin-Toutain, I.1
Piette, J.C.2
Diemert, M.C.3
Faucher, C.4
Jobic, L.5
Ankri, A.6
-
57
-
-
77449133188
-
B2 glycoprotein I b2GPI binds platelet factor 4 PF4: Implications for the pathogenesis of antiphospholipid syndrome
-
Sikara M, Routsias J, Samiotaki M, Panayotou G, Moutsopoulos H, Vlachoyiannopoulos P: b2 glycoprotein I (b2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome. Blood 115, 713-723 (2010).
-
(2010)
Blood
, vol.115
, pp. 713-723
-
-
Sikara, M.1
Routsias, J.2
Samiotaki, M.3
Panayotou, G.4
Moutsopoulos, H.5
Vlachoyiannopoulos, P.6
-
59
-
-
54049157838
-
Altered gene expression patterns in dendritic cells after severe trauma: Implications for systemic inflammation and organ injury
-
Maier M, Wutzler S, Bauer M, Trendafilov P, Henrich D, Marzi I: Altered gene expression patterns in dendritic cells after severe trauma: implications for systemic inflammation and organ injury. Shock 30, 344-351 (2008).
-
(2008)
Shock
, vol.30
, pp. 344-351
-
-
Maier, M.1
Wutzler, S.2
Bauer, M.3
Trendafilov, P.4
Henrich, D.5
Marzi, I.6
-
60
-
-
0035673283
-
2-glycoprotein I) antibodies: Effect on the proadhesive and proinflammatory phenotype
-
DOI 10.1002/1529-0131(200112)44:12<2870::AID-ART475>3.0.CO;2-Y
-
Meroni P, Raschi E, Testoni C et al.: Statins prevent endothelial cell activation induced by antiphospholipid (anti-β2- glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype. Arthritis Rheum. 44(12), 2870-2878 (2001). (Pubitemid 34016207)
-
(2001)
Arthritis and Rheumatism
, vol.44
, Issue.12
, pp. 2870-2878
-
-
Meroni, P.L.1
Raschi, E.2
Testoni, C.3
Tincani, A.4
Balestrieri, G.5
Molteni, R.6
Khamashta, M.A.7
Tremoli, E.8
Camera, M.9
-
61
-
-
0033586656
-
Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
-
Pierangeli S, Colden-Stanfield M, Liu X, Barker J, Anderson G, Harris E: Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation 99, 1997-2002 (1999). (Pubitemid 29183897)
-
(1999)
Circulation
, vol.99
, Issue.15
, pp. 1997-2002
-
-
Pierangeli, S.S.1
Colden-Stanfield, M.2
Liu, X.3
Barker, J.H.4
Anderson, G.L.5
Harris, E.N.6
-
62
-
-
34948885608
-
C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies
-
DOI 10.1196/annals.1422.058, Autoimmunity, Part D: Autoimmune Disease, Annus Mirabilis
-
Romay-Penabad Z, Liu X, Montiel-Manzano G, de Martinez E, Pierangeli S: C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies. Ann. NY Acad. Sci. 1108, 554-566 (2007). (Pubitemid 47528769)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1108
, pp. 554-566
-
-
Romay-Penabad, Z.1
Liu X, X.2
Montiel-Manzano, G.3
De Martinez, E.P.4
Pierangeli, S.S.5
-
63
-
-
54449091353
-
Immunological features of primary anti-phospholipid syndrome in connection with endothelial dysfunction
-
Soltesz P, Der H, Veres K et al.: Immunological features of primary anti-phospholipid syndrome in connection with endothelial dysfunction. Rheumatology 47, 1628-1634 (2008).
-
(2008)
Rheumatology
, vol.47
, pp. 1628-1634
-
-
Soltesz, P.1
Der, H.2
Veres, K.3
-
64
-
-
75349108595
-
Patients with antiphospholipid syndrome display endothelial perturbation
-
Cugno M, Borghi M, Lonati L et al.: Patients with antiphospholipid syndrome display endothelial perturbation. J. Autoimmunity 34, 105-110 (2010).
-
(2010)
J. Autoimmunity
, vol.34
, pp. 105-110
-
-
Cugno, M.1
Borghi, M.2
Lonati, L.3
-
65
-
-
77952946073
-
Arterial and venous thrombosis is associated with different angiogenic cytokine patterns in patients with antiphospholid syndrome
-
Smadja D, Gaussem P, Roncal C, Fischer AM, Emmerich J, Darnige L: Arterial and venous thrombosis is associated with different angiogenic cytokine patterns in patients with antiphospholid syndrome. Lupus 19(7), 837-843 (2010).
-
(2010)
Lupus
, vol.19
, Issue.7
, pp. 837-843
-
-
Smadja, D.1
Gaussem, P.2
Roncal, C.3
Fischer, A.M.4
Emmerich, J.5
Darnige, L.6
-
66
-
-
67649502333
-
Antiphospholipid antibodies may impair factor-XIIa-dependent activation of fibrinolysis in pregnancy: In vitro evidence with human endothelial cells in culture and monoclonal anticardiolipin antibodies
-
Lazaro I, Carmona F, Reverter J, Cervera R, Tassies D, Balasch J: Antiphospholipid antibodies may impair factor-XIIa-dependent activation of fibrinolysis in pregnancy: in vitro evidence with human endothelial cells in culture and monoclonal anticardiolipin antibodies. Am. J. Obstet. Gynecol. 201(87), e1-e6 (2009).
-
(2009)
Am. J. Obstet. Gynecol.
, vol.201
, Issue.87
-
-
Lazaro, I.1
Carmona, F.2
Reverter, J.3
Cervera, R.4
Tassies, D.5
Balasch, J.6
-
67
-
-
34547218488
-
2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome
-
DOI 10.1136/ard.2006.063909
-
Hamid C, Norgate K, D'Cruz D et al.: Anti-b2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome. Ann. Rheum. Dis. 66, 1000-1007 (2007). (Pubitemid 47122310)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.8
, pp. 1000-1007
-
-
Hamid, C.1
Norgate, K.2
D'Cruz, D.P.3
Khamashta, M.A.4
Arno, M.5
Pearson, J.D.6
Frampton, G.7
Murphy, J.J.8
-
68
-
-
18644361988
-
Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
-
DOI 10.1002/art.21009
-
Vega-Ostertag M, Casper K, Swerlick R, Ferrara D, Harris E, Pierangeli S: Involvement of p38 MAPK in the upregulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum. 52(5), 1545-1554 (2005). (Pubitemid 40663946)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.5
, pp. 1545-1554
-
-
Vega-Ostertag, M.1
Casper, K.2
Swerlick, R.3
Ferrara, D.4
Harris, E.N.5
Pierangeli, S.S.6
-
69
-
-
0142166253
-
E-Selectin mediates pathogenic effects of antiphospholipid antibodies
-
Espinola R, Liu X, Colden-Stanfield M, Hall J, Harris E, Pierangeli S: E-Selectin mediates pathogenic effects of antiphospholipid antibodies. J. Thromb. Haemost. 1(4), 843-848 (2003).
-
(2003)
J. Thromb. Haemost.
, vol.1
, Issue.4
, pp. 843-848
-
-
Espinola, R.1
Liu, X.2
Colden-Stanfield, M.3
Hall, J.4
Harris, E.5
Pierangeli, S.6
-
70
-
-
0035793334
-
Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin
-
Pierangeli S, Espinola R, Liu X, Harris E: Thrombogenic effects of antiphospholipid syndrome antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin. Circ. Res. 88, 245-250 (2001). (Pubitemid 32147315)
-
(2001)
Circulation Research
, vol.88
, Issue.2
, pp. 245-250
-
-
Pierangeli, S.S.1
Espinola, R.G.2
Liu, X.3
Harris, E.N.4
-
71
-
-
34848821297
-
P-selectin glycoprotein ligand-1 VNTR polymorphisms and risk of thrombosis in the antiphospholipid syndrome
-
DOI 10.1136/ard.2007.075945
-
Diz-Kucukkaya R, Inanc M, Afshar-Kharghan V, Zhang Q, Lopez J, Pekcelen Y: P-selectin glycoprotein ligand-1 VNTR polymorphisms and risk of thrombosis in the antiphospholipid syndrome. Ann. Rheum. Dis. 66, 1378-1380 (2007). (Pubitemid 47492485)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.10
, pp. 1378-1380
-
-
Diz-Kucukkaya, R.1
Inanc, M.2
Afshar-Kharghan, V.3
Zhang, Q.E.4
Lopez, J.A.5
Pekcelen, Y.6
-
72
-
-
35449001281
-
Activated protein C resistance determined with a thrombin generation-based test is associated with thrombotic events in patients with lupus anticoagulants
-
DOI 10.1111/j.1538-7836.2007.02734.x
-
Liestol S, Sandset P, Mowinckel MC, Wisloff F: Activated protein C resistance determined with a thrombin generation-based test is associated with thrombotic events in patients with lupus anticoagulants. J. Thromb. Haemost. 5, 2204-2210 (2007). (Pubitemid 47617872)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.11
, pp. 2204-2210
-
-
Liestol, S.1
Sandset, P.M.2
Mowinckel, M.-C.3
Wisloff, F.4
-
73
-
-
69549137883
-
The role of antiphospholipid antibodies toward the protein C protein S system in venous thromboembolic disease
-
Rossetto V, Spiezia L, Franz F et al.: The role of antiphospholipid antibodies toward the protein C/protein S system in venous thromboembolic disease. Am. J. Hematol. 84(9), 594-596 (2009).
-
(2009)
Am. J. Hematol.
, vol.84
, Issue.9
, pp. 594-596
-
-
Rossetto, V.1
Spiezia, L.2
Franz, F.3
-
74
-
-
34250736220
-
Autoantibodies against endothelial protein C receptor and the risk of a first deep vein thrombosis
-
DOI 10.1111/j.1538-7836.2007.02582.x
-
van Hylckama Vlieg A, Montes R, Rosendaal F, Hermida J: Autoantibodies against endothelial protein C receptor and the risk of a first deep vein thrombosis. J. Thromb. Haemost. 5, 1449-1454 (2007). (Pubitemid 46965374)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.7
, pp. 1449-1454
-
-
Van Hylckama Vlieg, A.1
Montes, R.2
Rosendaal, F.R.3
Hermida, J.4
-
75
-
-
4444301246
-
Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death
-
DOI 10.1182/blood-2004-03-0793
-
Hurtado V, Montes R, Gris J et al.: Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death. Blood 104, 1369-1374 (2004). (Pubitemid 39166513)
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1369-1374
-
-
Hurtado, V.1
Montes, R.2
Gris, J.-C.3
Bertolaccini, M.L.4
Alonso, A.5
Martinez-Gonzalez, M.A.6
Khamashta, M.A.7
Fukudome, K.8
Lane, D.A.9
Hermida, J.10
-
76
-
-
33751578678
-
Antibodies against the activated coagulation factor X FXa in the antiphospholipid syndrome that interfere with the FXa inactivation by antithrombin
-
Yang Y-H, Hwang K-K, FitzGerald J et al.: Antibodies against the activated coagulation factor X (FXa) in the antiphospholipid syndrome that interfere with the FXa inactivation by antithrombin. J. Immunol. 177(8219), 8225 (2006).
-
(2006)
J. Immunol.
, vol.177
, Issue.8219
, pp. 8225
-
-
Yang, Y.-H.1
Hwang, K.-K.2
FitzGerald, J.3
-
77
-
-
63149169674
-
Novel autoantibodies against the activated coagulation factor IX FIXa in the antiphospholipid syndrome that interpose the FIXa regulation by antithrombin
-
Yang Y-H, Chien D, Wu M et al.: Novel autoantibodies against the activated coagulation factor IX (FIXa) in the antiphospholipid syndrome that interpose the FIXa regulation by antithrombin. J. Immunol. 182, 1674-1680 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 1674-1680
-
-
Yang, Y.-H.1
Chien, D.2
Wu, M.3
-
78
-
-
33750020533
-
The effects of tissue factor pathway inhibitor and anti-β-2- glycoprotein-I IgG on thrombin generation
-
Lean S, Ellery P, Ivey L et al.: The effects of tissue factor pathway inhibitor and anti-β-2-glycoprotein-I IgG on thrombin generation. Haematologica 91, 1360-1366 (2006) (Pubitemid 44569809)
-
(2006)
Haematologica
, vol.91
, Issue.10
, pp. 1360-1366
-
-
Lean, S.Y.1
Ellery, P.2
Ivey, L.3
Thom, J.4
Oostryck, R.5
Leahy, M.6
Baker, R.7
Adams, M.8
-
79
-
-
34548816709
-
2-Glycoprotein I inhibits vonWillebrand factor-dependent platelet adhesion and aggregation
-
DOI 10.1182/blood-2006-10-053199
-
Hulstein J, Lenting P, de Laat B, Derksen R, Fijnheer R, de Groot P: β2-glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation. Blood 110, 1483-1491 (2007). (Pubitemid 47443963)
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1483-1491
-
-
Hulstein, J.J.J.1
Lenting, P.J.2
De Laat, B.3
Derksen, R.H.W.M.4
Fijnheer, R.5
De Groot, P.G.6
-
80
-
-
62449126466
-
Factor XIII-A subunit Val34Leu polymorphism is associated with the risk of thrombosis in patients with antiphospholipid antibodies and high fibrinogen levels
-
de la Red G, Tassies D, Espinosa G et al.: Factor XIII-A subunit Val34Leu polymorphism is associated with the risk of thrombosis in patients with antiphospholipid antibodies and high fibrinogen levels. Thromb. Haemost. 101, 312-316 (2009).
-
(2009)
Thromb. Haemost.
, vol.101
, pp. 312-316
-
-
De La Red, G.1
Tassies, D.2
Espinosa, G.3
-
81
-
-
68049110510
-
The effects of phosphatidylserine-dependent antiprothrombin antibody on thrombin generation
-
Sakai Y, Atsumi T, Ieko M et al.: The effects of phosphatidylserine- dependent antiprothrombin antibody on thrombin generation. Arthritis Rheum. 60(8), 2457-2467 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.8
, pp. 2457-2467
-
-
Sakai, Y.1
Atsumi, T.2
Ieko, M.3
-
82
-
-
33847415027
-
Increased plasma concentrations of antiprothrombin antibodies in women with recurrent spontaneous abortions
-
DOI 10.1373/clinchem.2006.073098
-
Sabatini L, Torricelli M, Scaccia V et al.: Increased plasma concentration of antiprothrombin antibodies in women with recurrent spontaneous abortions. Clin. Chem. 53, 228-232 (2007). (Pubitemid 46338266)
-
(2007)
Clinical Chemistry
, vol.53
, Issue.2
, pp. 228-232
-
-
Sabatini, L.1
Torricelli, M.2
Scaccia, V.3
Fineschi, D.4
Pescaglini, M.5
Gasparri, L.6
Florio, P.7
Petraglia, F.8
-
83
-
-
33748748970
-
A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells
-
DOI 10.1111/j.1365-2141.2006.06283.x
-
Vega-Ostertag M, Liu X, Kwank-Ki H, Chen P, Pierangeli S: A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells. Br. J. Haematol. 135(2), 214-219 (2006). (Pubitemid 44401619)
-
(2006)
British Journal of Haematology
, vol.135
, Issue.2
, pp. 214-219
-
-
Vega-Ostertag, M.1
Liu, X.2
Kwan-Ki, H.3
Chen, P.4
Pierangeli, S.5
-
84
-
-
59649088830
-
β2-Glycoprotein I is a cofactor for tissue plasminogen activatormediated plasminogen activation
-
Bu C, Gao L, Xie W et al.: β2-glycoprotein I is a cofactor for tissue plasminogen activatormediated plasminogen activation. Arthritis Rheum. 60(2), 559-568 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.2
, pp. 559-568
-
-
Bu, C.1
Gao, L.2
Xie, W.3
-
85
-
-
77954540087
-
Increase in plasma thrombin-activatable fibrinolysis inhibitor may not contribute to thrombotic tendency in antiphospholipid syndrome because of inhibitory potential of antiphospholipid antibodies toward TAFI activation
-
Ieko M, Yoshida M, Naito S et al.: Increase in plasma thrombin-activatable fibrinolysis inhibitor may not contribute to thrombotic tendency in antiphospholipid syndrome because of inhibitory potential of antiphospholipid antibodies toward TAFI activation. Int. J. Haematol. 91, 776-783 (2010).
-
(2010)
Int. J. Haematol.
, vol.91
, pp. 776-783
-
-
Ieko, M.1
Yoshida, M.2
Naito, S.3
-
86
-
-
67651205888
-
STAT4 single nucleotide polymorphism rs7574865 G T as a risk for antiphospholipid syndrome
-
Horita T, Atusmi T, Yoshida N et al.: STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome. Ann. Rheum. Dis. 68, 1366-1367 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1366-1367
-
-
Horita, T.1
Atusmi, T.2
Yoshida, N.3
-
87
-
-
58849119882
-
Pro-inflammatory genotype as a risk factor for aPL-associated thrombosis: Report of a family with multiple anti-phospholipid positive members
-
De Angelis V, Scurati S, Raschi E et al.: Pro-inflammatory genotype as a risk factor for aPL-associated thrombosis: report of a family with multiple anti-phospholipid positive members. J. Autoimmunity 32, 60-63 (2009).
-
(2009)
J. Autoimmunity
, vol.32
, pp. 60-63
-
-
De Angelis, V.1
Scurati, S.2
Raschi, E.3
-
88
-
-
68049107373
-
Association of STAT4 and BLK but not BANK1 or IRF5 with primary antiphospholipid syndrome
-
Yin H, Borghi M, Delgado-Vega A, Tincani A, Meroni P, Alarcon-Riquelme M: Association of STAT4 and BLK, but not BANK1 or IRF5 with primary antiphospholipid syndrome. Arthritis Rheum. 60(8), 2468-2471 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.8
, pp. 2468-2471
-
-
Yin, H.1
Borghi, M.2
Delgado-Vega, A.3
Tincani, A.4
Meroni, P.5
Alarcon-Riquelme, M.6
-
89
-
-
79954444111
-
Increased level of tumor necrosis factor-a in patients with antiphospholipid syndrome: Marker not only of inflammation but also of the prothrombotic state
-
Swadzba J, Iwaniec T, Musial J: Increased level of tumor necrosis factor-a in patients with antiphospholipid syndrome: marker not only of inflammation but also of the prothrombotic state. Rheumatol. Int. 31(3), 307-313 (2009).
-
(2009)
Rheumatol. Int.
, vol.31
, Issue.3
, pp. 307-313
-
-
Swadzba, J.1
Iwaniec, T.2
Musial, J.3
-
90
-
-
34547733912
-
2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid rafts
-
DOI 10.1002/art.22802
-
Sorice M, Longo A, Capozzi A et al.: Anti-β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor a and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum. 56, 2687-2697 (2007). (Pubitemid 47237287)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.8
, pp. 2687-2697
-
-
Sorice, M.1
Longo, A.2
Capozzi, A.3
Garofalo, T.4
Misasi, R.5
Alessandri, C.6
Conti, F.7
Buttari, B.8
Rigano, R.9
Ortona, E.10
Valesini, G.11
-
91
-
-
34250721890
-
Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
-
DOI 10.1136/ard.2006.065037
-
Pierangeli S, Vega-Ostertag M, Raschi E et al.: Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann. Rheum. Dis. 66, 1327-1333 (2007). (Pubitemid 47492476)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.10
, pp. 1327-1333
-
-
Pierangeli, S.S.1
Vega-Ostertag, M.E.2
Raschi, E.3
Liu, X.4
Romay-Penabad, Z.5
De Micheli, V.6
Galli, M.7
Moia, M.8
Tincani, A.9
Borghi, M.O.10
Nguyen-Oghalai, T.11
Meroni, P.L.12
-
92
-
-
77956395908
-
TLR2 is one of the endothelial receptors for β2-glycoprotein I
-
Alard J, Gaillard F, Daridon C, Shoenfeld Y, Jamin C, Youinou P: TLR2 is one of the endothelial receptors for β2-glycoprotein I. J. Immunol. 185, 1550-1557 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 1550-1557
-
-
Alard, J.1
Gaillard, F.2
Daridon, C.3
Shoenfeld, Y.4
Jamin, C.5
Youinou, P.6
-
93
-
-
67650067301
-
TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of the IL-1b and caspase-1 in monocytes and dendritic cells
-
Hurst J, Prinz N, Lorenz M et al.: TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of the IL-1b and caspase-1 in monocytes and dendritic cells. Immunobiology 214, 683-691 (2009).
-
(2009)
Immunobiology
, vol.214
, pp. 683-691
-
-
Hurst, J.1
Prinz, N.2
Lorenz, M.3
-
94
-
-
38049023658
-
2-glycoprotein I in patients with antiphospholipid syndrome
-
DOI 10.1182/blood-2007-07-100008
-
Yamaguchi Y, Seta N, Kaburaki J, Kobayashi K, Matsuura E, Matsuura E: Excessive exposure to anionic surfaces maintains autoantibody response to β2-glycoprotein I in patients with antiphospholipid syndrome. Blood 110, 4312-4318 (2007). (Pubitemid 351377796)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4312-4318
-
-
Yamaguchi, Y.1
Seta, N.2
Kaburaki, J.3
Kobayashi, K.4
Matsuura, E.5
Kuwana, M.6
-
95
-
-
67449159236
-
Complement activation in patients with primary antiphospholipid syndrome
-
Oku K, Atsumi T, Bohgaki M et al.: Complement activation in patients with primary antiphospholipid syndrome. Ann. Rheum. Dis. 68, 1030-1035 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1030-1035
-
-
Oku, K.1
Atsumi, T.2
Bohgaki, M.3
-
96
-
-
65149101917
-
Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid syndrome
-
Peerschke E, Yin W, Alpert D, Roubey R, Salmon J, Ghebrehiwet B: Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid syndrome. Lupus 18, 530-538 (2009).
-
(2009)
Lupus
, vol.18
, pp. 530-538
-
-
Peerschke, E.1
Yin, W.2
Alpert, D.3
Roubey, R.4
Salmon, J.5
Ghebrehiwet, B.6
-
97
-
-
41849106908
-
Antiphospholipid syndrome patients display reduced titers of soluble CD21 in their sera irrespective of circulating anti-β2-glycoprotein-I autoantibodies
-
Singh A, Blank M, Shoenfeld Y, Illges H: Antiphospholipid syndrome patients display reduced titers of soluble CD21 in their sera irrespective of circulating anti-β2- glycoprotein-I autoantibodies. Rheumatol. Int. 28, 661-665 (2008).
-
(2008)
Rheumatol. Int.
, vol.28
, pp. 661-665
-
-
Singh, A.1
Blank, M.2
Shoenfeld, Y.3
Illges, H.4
-
98
-
-
33749118495
-
A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways
-
Ritis K, Doumas M, Mastellos D et al.: A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. J. Immunol. 177, 4794-4802 (2006). (Pubitemid 44469814)
-
(2006)
Journal of Immunology
, vol.177
, Issue.7
, pp. 4794-4802
-
-
Ritis, K.1
Doumas, M.2
Mastellos, D.3
Micheli, A.4
Giaglis, S.5
Magotti, P.6
Rafail, S.7
Kartalis, G.8
Sideras, P.9
Lambris, J.D.10
-
99
-
-
22244485396
-
Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
-
DOI 10.1002/art.21157
-
Pierangeli S, Girardi G, Vega-Ostertag M, Liu X, Espinola R, Salmon J: Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum. 52(7), 2120-2124 (2005). (Pubitemid 40994335)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.7
, pp. 2120-2124
-
-
Pierangeli, S.S.1
Girardi, G.2
Vega-Ostertag, M.3
Liu, X.4
Espinola, R.G.5
Salmon, J.6
-
100
-
-
77951971046
-
The role of defective clearance of apoptotic cells in systemic autoimmunity
-
Munoz L, Lauber K, Schiller M, Manfredi A, Hermann M: The role of defective clearance of apoptotic cells in systemic autoimmunity. Nat. Rev. Rheumatol. 6(5), 280-289 (2010).
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, Issue.5
, pp. 280-289
-
-
Munoz, L.1
Lauber, K.2
Schiller, M.3
Manfredi, A.4
Hermann, M.5
-
101
-
-
33846821657
-
Antiphospholipid reactivity against cardiolipin metabolites occurring during endothelial cell apoptosis
-
Alessandri C, Sorice M, Bombardieri M et al.: Antiphospholipid reactivity against cardiolipin metabolites occurring during endothelial cell apoptosis. Arthritis Res. Ther. 8, R180 (2006).
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Alessandri, C.1
Sorice, M.2
Bombardieri, M.3
-
102
-
-
63149195539
-
Anti-endothelial antibodies interfere in apoptotic cell clearance and promote thrombosis in patients with antiphospholipid syndrome
-
Graham A, Ford I, Morrison R, Barker R, Greaves M, Erwig L-P: Anti-endothelial antibodies interfere in apoptotic cell clearance and promote thrombosis in patients with antiphospholipid syndrome. J. Immunol. 182, 1756-1762 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 1756-1762
-
-
Graham, A.1
Ford, I.2
Morrison, R.3
Barker, R.4
Greaves, M.5
Erwig, L.-P.6
-
103
-
-
70349116054
-
Vascular abnormalities paraoxonase activity and dysfunctional HDL in primary antiphospholipid syndrome
-
Charakida M, Besler C, Batuca J et al.: Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome. JAMA 302(11), 1210-1217 (2009).
-
(2009)
JAMA
, vol.302
, Issue.11
, pp. 1210-1217
-
-
Charakida, M.1
Besler, C.2
Batuca, J.3
-
104
-
-
0035967833
-
2-glycoprotein I)
-
DOI 10.1016/S0024-3205(01)01164-X, PII S002432050101164X
-
Lin K, Pan J, Yang D et al.: Evidence for inhibition of low density lipoprotein oxidation and cholesterol accumulation by apolipoprotein H (β2-glycoprotein I).Life Sci. 69(6), 707-719 (2001). (Pubitemid 32673629)
-
(2001)
Life Sciences
, vol.69
, Issue.6
, pp. 707-719
-
-
Lin, K.-Y.1
Pan, J.-P.2
Yang, D.-L.3
Huang, K.-T.4
Chang, M.-S.5
Ding, P.Y.-A.6
Chiang, A.-N.7
-
105
-
-
37649024028
-
Distinguished effects of antiphospholipid antibodies and anti-oxidized LDL antibodies on oxidized LDL uptake by macrophages
-
Kobayashi K, Tada K, Ueno T et al.: Distinguished effects of antiphospholipid antibodies and anti-oxidized LDL antibodies on oxidized LDL uptake by macrophages. Lupus 16, 929-938 (2007).
-
(2007)
Lupus
, vol.16
, pp. 929-938
-
-
Kobayashi, K.1
Tada, K.2
Ueno, T.3
-
106
-
-
34548543161
-
2-glycoprotein I complexes with lipid vesicles in macrophages: Implications on the development of antiphospholipid syndrome
-
DOI 10.1016/j.jaut.2007.07.003, PII S0896841107000820
-
Kajiwara T, Yasuda T, Matsuura E: Intracellular trafficking of β2-glycoprotein I complexes with lipid vesicles in macrophages: implications on the development of antiphospholipid syndrome. J. Autoimmunity 29, 164-173 (2007). (Pubitemid 47385117)
-
(2007)
Journal of Autoimmunity
, vol.29
, Issue.2-3
, pp. 164-173
-
-
Kajiwara, T.1
Yasuda, T.2
Matsuura, E.3
-
107
-
-
48049112768
-
Antibodies to oxidized LDL β2-glycoprotein I in antiphospholipid syndrome patients with venous and arterial thromboembolism
-
Pengo V, Bison E, Ruffatti A, Iliceto S: Antibodies to oxidized LDL/β2- glycoprotein I in antiphospholipid syndrome patients with venous and arterial thromboembolism. Thromb. Res. 122, 556-559 (2008).
-
(2008)
Thromb. Res.
, vol.122
, pp. 556-559
-
-
Pengo, V.1
Bison, E.2
Ruffatti, A.3
Iliceto, S.4
-
108
-
-
3242706212
-
Histologic features of placentas and abortion specimens from women with antiphospholipid and antiphospholipis-like syndromes
-
DOI 10.1016/j.placenta.2003.12.006, PII S0143400403003254
-
Van Horn J, Craven C, Wark K, Branch D, Silver R: Histologic features of placentas and abortion specimens from women with antiphospholipid and antiphospholipid-like syndromes. Placenta 25, 642-648 (2004). (Pubitemid 38950318)
-
(2004)
Placenta
, vol.25
, Issue.7
, pp. 642-648
-
-
Van Horn, J.T.1
Craven, C.2
Ward, K.3
Branch, D.W.4
Silver, R.M.5
-
109
-
-
0030064150
-
Placental changes in a first trimester missed abortion in maternal systemic lupus erythematosus with antiphospholipid syndrome: A case report and review of the literature
-
DOI 10.1016/S0046-8177(96)90377-9
-
Nayar R, Lage J: Placental changes in a first trimester missed abortion in maternal systemic lupus erythematosus with antiphospholipid syndrome: a case report and review of the literature. Hum. Pathol. 27, 201-206 (1996). (Pubitemid 26049477)
-
(1996)
Human Pathology
, vol.27
, Issue.2
, pp. 201-206
-
-
Nayar, R.1
Lage, J.M.2
-
110
-
-
0027146697
-
The effect of immunoglobulin G fractions from patients with lupus anticoagulant on placental prostacyclin and thromboxane production
-
Peaceman A, Rehnberg K: The effect of immunoglobulin G fractions from patients with lupus anticoagulant on placental prostacyclin and thromboxane production. Am. J. Obstet. Gynecol. 169, 1403-1406 (1993). (Pubitemid 24009168)
-
(1993)
American Journal of Obstetrics and Gynecology
, vol.169
, Issue.6
, pp. 1403-1406
-
-
Peaceman, A.M.1
Rehnberg, K.A.2
-
111
-
-
0028586742
-
Reduction of annexin-V placental anticoagulant protein-I on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion
-
Rand J, Wu X, Guller S et al.: Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion. Am. J. Obstet. Gynecol. 171(6), 1566-1572 (1994).
-
(1994)
Am. J. Obstet. Gynecol.
, vol.171
, Issue.6
, pp. 1566-1572
-
-
Rand, J.1
Wu, X.2
Guller, S.3
-
112
-
-
0037059463
-
Molecular pathogenesis of the antiphospholipid syndrome
-
DOI 10.1161/hh0102.102795
-
Rand J: Molecular pathogenesis of the antiphospholipid syndrome. Circ. Res. 11, 29-37 (2002). (Pubitemid 34074605)
-
(2002)
Circulation Research
, vol.90
, Issue.1
, pp. 29-37
-
-
Rand, J.H.1
-
113
-
-
77951217438
-
The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: Role in pregnancy losses and thrombosis
-
Rand J, Wu X, Quinn A, Taatjes D: The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: role in pregnancy losses and thrombosis. Lupus 19, 460-469 (2010).
-
(2010)
Lupus
, vol.19
, pp. 460-469
-
-
Rand, J.1
Wu, X.2
Quinn, A.3
Taatjes, D.4
-
114
-
-
33745599584
-
Anti-beta-2 glycoprotein I antibodies affect Bcl-2 and Bax trophoblast expression without evidence of apoptosis
-
DOI 10.1196/annals.1351.034
-
Di Simone N, Castellani R, Raschi E, Borghi M, Meroni P, Caruso A: Anti-b-2 glycoprotein i antibodies affect Bcl-2 and Bax trophoblast expression without evidence of apoptosis. Ann. NY Acad. Sci. 1069, 364-376 (2006). (Pubitemid 43989879)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1069
, pp. 364-376
-
-
Di Simone, N.1
Castellani, R.2
Raschi, E.3
Borghi, M.O.4
Meroni, P.L.5
Caruso, A.6
-
115
-
-
67650651969
-
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4 MyD88 pathway
-
Mulla M, Brosens J, Chamley L et al.: Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. Am. J. Reprod. Immunol. 62, 96-111 (2009).
-
(2009)
Am. J. Reprod. Immunol.
, vol.62
, pp. 96-111
-
-
Mulla, M.1
Brosens, J.2
Chamley, L.3
-
116
-
-
77953039466
-
Antiphospholipid antibodies limit trophoblast migration by reducing IL-6 production and STAT3 activity
-
Mulla M, Myrtolli K, Brosens J et al.: antiphospholipid antibodies limit trophoblast migration by reducing IL-6 production and STAT3 activity. Am. J. Reprod. Immunol. 63, 339-348 (2010).
-
(2010)
Am. J. Reprod. Immunol.
, vol.63
, pp. 339-348
-
-
Mulla, M.1
Myrtolli, K.2
Brosens, J.3
-
117
-
-
72849110555
-
Detailed analysis of peripheral blood natural killer NK cells in women with recurrent miscarriage
-
King K, Smith S, Chapman M, Sacks G: Detailed analysis of peripheral blood natural killer (NK) cells in women with recurrent miscarriage. Hum. Reprod. 25(1), 52-58 (2010).
-
(2010)
Hum. Reprod.
, vol.25
, Issue.1
, pp. 52-58
-
-
King, K.1
Smith, S.2
Chapman, M.3
Sacks, G.4
-
118
-
-
34848864591
-
High levels of NK cells in the peripheral blood of patients affected with anti-phospholipid syndrome and recurrent spontaneous abortion: A potential new hypothesis
-
DOI 10.1093/rheumatology/kem197
-
Perricone C, De Carolis C, Giacomelli R et al.: High levels of NK cells in the peripheral blood of patients affected with antiphospholipid syndrome and recurrent sponatenous abortion: a potential new hypothesis. Rheumatology 46, 1574-1578 (2007). (Pubitemid 47500573)
-
(2007)
Rheumatology
, vol.46
, Issue.10
, pp. 1574-1578
-
-
Perricone, C.1
De Carolis, C.2
Giacomelli, R.3
Zaccari, G.4
Cipriani, P.5
Bizzi, E.6
Perricone, R.7
-
119
-
-
34948903311
-
Tissue factor: A link between C5a and neutrophil activation in antiphospholipid antibody-induced fetal injury
-
DOI 10.1182/blood-2007-01-070631
-
Redecha P, Tilley R, Tencati M et al.: Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood 110, 2423-2431 (2007). (Pubitemid 47523163)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2423-2431
-
-
Redecha, P.1
Tilley, R.2
Tencati, M.3
Salmon, J.E.4
Kirchhofer, D.5
Mackman, N.6
Girardi, G.7
-
120
-
-
55849112296
-
Neutrophil activation by the tissue factor factor VIIa PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
-
Redecha P, Franzke C-W, Ruf W, Mackman N, Girardi G: Neutrophil activation by the tissue factor/factor VIIa/ PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J. Clin. Immunol. 118(10), 3453-3454 (2008).
-
(2008)
J. Clin. Immunol.
, vol.118
, Issue.10
, pp. 3453-3454
-
-
Redecha, P.1
Franzke, C.-W.2
Ruf, W.3
Mackman, N.4
Girardi, G.5
-
121
-
-
77955343208
-
Antiphospholipid antibodies affect human endometrial angiogenesis
-
Di Simone N, Di Nicuolo F, D'Ippolito S et al.: Antiphospholipid antibodies affect human endometrial angiogenesis. Biol. Reprod. 83, 212-219 (2010).
-
(2010)
Biol. Reprod.
, vol.83
, pp. 212-219
-
-
Di Simone, N.1
Di Nicuolo, F.2
Dippolito, S.3
-
122
-
-
78649289804
-
Prolactins role in the pathogenesis of the antiphospholipid syndrome
-
Praprotnik S, Agmon-Levin N, Porat-Katz B et al.: Prolactin's role in the pathogenesis of the antiphospholipid syndrome. Lupus 19(13), 1515-1519 (2010).
-
(2010)
Lupus
, vol.19
, Issue.13
, pp. 1515-1519
-
-
Praprotnik, S.1
Agmon-Levin, N.2
Porat-Katz, B.3
-
123
-
-
65349188214
-
In vivo inhibition of antiphospholipid antibody-induced pathogenecity utilizing the antigenic target peptide domain of β2-glycoprotein I: Proof of concept
-
Ioannou Y, Romay-Penabad Z, Pericleous C et al.: In vivo inhibition of antiphospholipid antibody-induced pathogenecity utilizing the antigenic target peptide domain of β2- glycoprotein I: proof of concept. J. Thromb. Haemost. 7, 833-842 (2009).
-
(2009)
J. Thromb. Haemost.
, vol.7
, pp. 833-842
-
-
Ioannou, Y.1
Romay-Penabad, Z.2
Pericleous, C.3
-
124
-
-
74849122596
-
Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: Extension of a phase II double-blind placebo-controlled dose-ranging study
-
Jacobi A, Huand W, Wang T et al.: Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a Phase II, double-blind, placebo-controlled, dose-ranging study. Arthritis Rheum. 62(1), 201-210 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, Issue.1
, pp. 201-210
-
-
Jacobi, A.1
Huand, W.2
Wang, T.3
-
125
-
-
69749120918
-
A phase II randomized double-blind placebocontrolled dose-ranging study of belimumab in patients with active systemic lupus erythematosus
-
Wallace D, Stohl W, Furie R et al.: A Phase II, randomized, double-blind, placebocontrolled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. Arthritis Rheum. 61(9), 1168-1178 (2009).
-
(2009)
Arthritis Rheum.
, vol.61
, Issue.9
, pp. 1168-1178
-
-
Wallace, D.1
Stohl, W.2
Furie, R.3
-
126
-
-
77957004137
-
B-lymphocyte stimulator a proliferationinducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin
-
Dillon S, Harder B, Lewis K et al.: B-lymphocyte stimulator/a proliferationinducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin. Arthritis Res. Ther. 12(2), R48 (2010).
-
(2010)
Arthritis Res. Ther.
, vol.12
, Issue.2
-
-
Dillon, S.1
Harder, B.2
Lewis, K.3
-
127
-
-
51849128320
-
Prevention of murine antiphospholipid syndrome by BAFF blockade
-
Kahn P, Ramanujam M, Bethunaickan R et al.: Prevention of murine antiphospholipid syndrome by BAFF blockade. Arthritis Rheum. 58(9), 2824-2834 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.9
, pp. 2824-2834
-
-
Kahn, P.1
Ramanujam, M.2
Bethunaickan, R.3
-
128
-
-
76049120027
-
Pharmacokinetics of LJP 993 a tetrameric conjugate of domain 1 of β2-glycoprotein I for antiphospholipid syndrome
-
Jia L, Gu Y, Zeng E, Linnik M, Jones D: Pharmacokinetics of LJP 993, a tetrameric conjugate of domain 1 of β2-glycoprotein I for antiphospholipid syndrome. Lupus 19(2), 130-137 (2010).
-
(2010)
Lupus
, vol.19
, Issue.2
, pp. 130-137
-
-
Jia, L.1
Gu, Y.2
Zeng, E.3
Linnik, M.4
Jones, D.5
-
129
-
-
0035207161
-
2GPI immune response
-
DOI 10.1021/bc015512x
-
Jones D, Cockerill K, Gamino C et al.: Synthesis of LJP 993, a multivalent conjugate of the N-terminal domain of b2GPI and suppression of an anti-b2GPI immune response. Bioconjugate Chem. 12(6), 1012-1020 (2001). (Pubitemid 33136873)
-
(2001)
Bioconjugate Chemistry
, vol.12
, Issue.6
, pp. 1012-1020
-
-
Jones, D.S.1
Cockerill, K.A.2
Gamino, C.A.3
Hammaker, J.R.4
Hayag, M.S.5
Iverson, G.M.6
Linnik, M.D.7
McNeeley, P.A.8
Tedder, M.E.9
Ton-Nu, H.10
Victoria, E.J.11
-
130
-
-
0029990745
-
Hydroxychloroquine use in the Baltimore Lupus Cohort: Effects on lipids, glucose and thrombosis
-
Petri M: Hydroxychloroquine use in the Baltimore Lupus Cohort: effects on lipid, glucose and thrombosis. Lupus 5(Suppl. 1), S16-S22 (1996). (Pubitemid 26196736)
-
(1996)
Lupus
, vol.5
, Issue.SUPPL. 1
-
-
Petri, M.1
-
131
-
-
0031442025
-
Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice
-
Edwards M, Pierangeli S, Liu X, Barker J, Anderson G, Harris E: Hydroxochloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. Circulation 96(12), 4380-4384 (1997). (Pubitemid 28007469)
-
(1997)
Circulation
, vol.96
, Issue.12
, pp. 4380-4384
-
-
Edwards, M.H.1
Pierangeli, S.2
Liu, X.3
Barker, J.H.4
Anderson, G.5
Nigel Harris, E.6
-
132
-
-
7244237671
-
Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells
-
DOI 10.1111/j.1538-7836.2004.00896.x
-
Ferrara D, Swerlick R, Casper K et al.: Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells. J. Thromb. Haemost. 2(9), 1558-1563 (2004). (Pubitemid 40186171)
-
(2004)
Journal of Thrombosis and Haemostasis
, vol.2
, Issue.9
, pp. 1558-1563
-
-
Ferrara, D.E.1
Swerlick, R.2
Casper, K.3
Meroni, P.L.4
Vega-Ostertag, M.E.5
Harris, E.N.6
Pierangeli, S.S.7
-
133
-
-
0242721975
-
Inhibition of the Thrombogenic and Inflammatory Properties of Antiphospholipid Antibodies by Fluvastatin in an In Vivo Animal Model
-
DOI 10.1002/art.11449
-
Ferrara D, Liu X, Espinola R et al.: Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal model. Arthritis Rheum. 48(11), 3272-3279 (2003). (Pubitemid 37409342)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.11
, pp. 3272-3279
-
-
Ferrara, D.E.1
Liu, X.2
Espinola, R.G.3
Meroni, P.L.4
Abukhalaf, I.5
Harris, E.N.6
Pierangeli, S.S.7
-
134
-
-
70049117028
-
Statins for the treatment of antiphospholipid syndrome
-
Jajoria P, Murthy V, Papalardo E, Romay-Penabad Z, Gleason C, Pierangeli S: Statins for the treatment of antiphospholipid syndrome? Ann. NY Acad. Sci. 1173, 736-745 (2009).
-
(2009)
Ann. NY Acad. Sci.
, vol.1173
, pp. 736-745
-
-
Jajoria, P.1
Murthy, V.2
Papalardo, E.3
Romay-Penabad, Z.4
Gleason, C.5
Pierangeli, S.6
-
135
-
-
34948875756
-
In vivo effects of an inhibitor of nuclear factor-kappa B on thrombogenic properties of antiphospholipid antibodies
-
DOI 10.1196/annals.1422.057, Autoimmunity, Part D: Autoimmune Disease, Annus Mirabilis
-
Montiel-Manzano G, Romay-Penabad Z, de Martinez E et al.: In vivo effects of an inhibitor of nuclear factor-kB on thrombogenic properties of antiphospholipid antibodies. Ann. NY Acad. Sci. 1108, 540-553 (2007). (Pubitemid 47528768)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1108
, pp. 540-553
-
-
Montiel-Manzano, G.1
Romay-Penabad, Z.2
De Martinez, E.P.3
Meillon-Garcia, L.A.4
Garcia-Latorre, E.5
Reyes-Maldonado, E.6
Pierangeli, S.S.7
-
136
-
-
75749127860
-
Improved pain physical functioning and health status in patients with rheumatoid arthritis treated with CP-690 550 an orally active Janus kinase JAK
-
Coombs J, Bloom B, Breedveld F et al.: Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomized, double-blind placebo controlled trial. Ann. Rheum. Dis. 69(2), 413-416 (2010).
-
(2010)
Ann. Rheum. Dis.
, vol.69
, Issue.2
, pp. 413-416
-
-
Coombs, J.1
Bloom, B.2
Breedveld, F.3
-
137
-
-
67650093218
-
The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind placebo-controlled phase IIa trial of three dosage levels of CP-690 550 versus placebo
-
Kremer J, Bloom B, Breedveld F et al.: The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled Phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum. 60(7), 1895-1905 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.7
, pp. 1895-1905
-
-
Kremer, J.1
Bloom, B.2
Breedveld, F.3
-
138
-
-
77957333252
-
An oral spleen tyrosine kinase Syk inhibitor for rheumatoid arthritis
-
Weinblatt M, Kavanaugh A, Genovese M, Musser T, Grossbard E, Magilavy D: An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis. N. Engl. J. Med. 363(14), 1303-1312 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, Issue.14
, pp. 1303-1312
-
-
Weinblatt, M.1
Kavanaugh, A.2
Genovese, M.3
Musser, T.4
Grossbard, E.5
Magilavy, D.6
|