Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-κB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway

Arthritis and Rheumatism

Volumn 54, Issue 1, 2006, Pages 301-311

  López Pedrera, Chary ^a   Buendía, Paula ^a   Cuadrado, Maria José ^b   Siendones, Emilio ^a   Aguirre, Maria Angeles ^a   Barbarroja, Nuria ^a   Montiel Duarte, Cristina ^c   Torres, Antonio ^a   Khamashta, Munther ^b   Velasco, Francisco ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPID ANTIBODY; SN 50; THROMBOPLASTIN; TRANSCRIPTION FACTOR REL;

ADULT; ANTIBODY PRODUCTION; ARTICLE; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ANALYSIS; FEMALE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALE; MONOCYTE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THROMBOSIS;

ADULT; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; FEMALE; HUMANS; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE KINASE 1; MIDDLE AGED; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN TRANSPORT; THROMBOPLASTIN;

EID: 31044449865     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21549     Document Type: Article

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