TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1β and caspase-1 in monocytes and dendritic cells

Immunobiology

Volumn 214, Issue 8, 2009, Pages 683-691

  Hurst, Julia ^a   Prinz, Nadine ^a   Lorenz, Mareike ^a   Bauer, Stefan ^b   Chapman, Joab ^c   Lackner, Karl J ^a   von Landenberg, Philipp ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Caspase 1; Dendritic cells; Interleukin 1 beta; Monocytes; TLR7; TLR8

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIGAND; MESSENGER RNA; PHOSPHOLIPID ANTIBODY; RESIQUIMOD; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA;

ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MALE; MONOCYTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; CASPASE 1; CELL SEPARATION; DENDRITIC CELLS; ENZYME INDUCTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; IMIDAZOLES; INTERLEUKIN-1BETA; LIGANDS; MALE; MONOCYTES; OLIGONUCLEOTIDES, ANTISENSE; REGULATORY SEQUENCES, NUCLEIC ACID; RNA; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 67650067301     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.12.003     Document Type: Article

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