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Volumn 16, Issue 4, 2011, Pages 1302-1314

Signalling pathways and vascular calcification

Author keywords

Review; Signalling pathways; Vascular calcification; Vascular smooth muscle cell

Indexed keywords

BONE MORPHOGENETIC PROTEIN; INTERLEUKIN 6; NOTCH RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; WNT PROTEIN;

EID: 79955035385     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3790     Document Type: Article
Times cited : (56)

References (119)
  • 1
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz S.A., M.Y. Speer, G. Curinga, H.Y.Yang, P. Haynes, R. Aebersold, T. Schinke, G. Karsenty, and C.M. Giachelli, Smooth Muscle Cell Phenotypic Transition Associated With Calcification: Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers. Circ Res 89, 1147-1154 (2001) (Pubitemid 34627872)
    • (2001) Circulation Research , vol.89 , Issue.12 , pp. 1147-1154
    • Steitz, S.A.1    Speer, M.Y.2    Curinga, G.3    Yang, H.-Y.4    Haynes, P.5    Aebersold, R.6    Schinke, T.7    Karsenty, G.8    Giachelli, C.M.9
  • 2
    • 85047680880 scopus 로고
    • Approaches to the development of selective inhibitors of vascular smooth muscle cell proliferation
    • Weissberg P.L., D.J. Grainger, C.M. Shanahan, and J.C. Metcalfe, Approaches to the development of selective inhibitors of vascular smooth muscle cell proliferation. Cardiovasc Res 27, 1191-1198 (1993) (Pubitemid 23250895)
    • (1993) Cardiovascular Research , vol.27 , Issue.7 , pp. 1191-1198
    • Weissberg, P.L.1    Grainger, D.J.2    Shanahan, C.M.3    Metcalfe, J.C.4
  • 3
    • 0033598796 scopus 로고    scopus 로고
    • Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: Evidence for smooth muscle cell-mediated vascular calcification
    • Shanahan C.M., N.R. Cary, J.R. Salisbury, D. Proudfoot, P.L.Weissberg, and M.E. Edmonds, Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation 100, 2168-2176 (1999)
    • (1999) Circulation , vol.100 , pp. 2168-2176
    • Shanahan, C.M.1    Cary, N.R.2    Salisbury, J.R.3    Proudfoot, D.4    Weissberg, P.L.5    Edmonds, M.E.6
  • 4
    • 0037341318 scopus 로고    scopus 로고
    • Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification
    • DOI 10.1161/01.ATV.0000059406.92165.31
    • Tyson K.L., J.L. Reynolds, R. McNair, Q. Zhang, P.L. Weissberg, and C.M.Shanahan, Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification. Arterioscler Thromb and Vasc Biol23, 489-494 (2003) (Pubitemid 36337227)
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.3 , pp. 489-494
    • Tyson, K.L.1    Reynolds, J.L.2    McNair, R.3    Zhang, Q.4    Weissberg, P.L.5    Shanahan, C.M.6
  • 7
    • 17644398457 scopus 로고    scopus 로고
    • Regulation of vascular calcification: Roles of phosphate and osteopontin
    • DOI 10.1161/01.RES.0000161997.24797.c0
    • Giachelli C.M., M.Y. Speer, X. Li, R.M. Rajachar, and H. Yang, Regulation of vascular calcification: roles of phosphate and osteopontin. Circ Res 96, 717-722 (2005) (Pubitemid 40559510)
    • (2005) Circulation Research , vol.96 , Issue.7 , pp. 717-722
    • Giachelli, C.M.1    Speer, M.Y.2    Li, X.3    Rajachar, R.M.4    Yang, H.5
  • 8
    • 33749132161 scopus 로고    scopus 로고
    • Molecular mechanisms mediating vascular calcification: Role of matrix Gla protein (review article)
    • DOI 10.1111/j.1440-1797.2006.00660.x
    • Proudfoot D. and C.M. Shanahan, Molecular mechanisms mediating vascular calcification: Role of matrix Gla protein. Nephrology 11, 455-461 (2006) (Pubitemid 44470096)
    • (2006) Nephrology , vol.11 , Issue.5 , pp. 455-461
    • Proudfoot, D.1    Shanahan, C.M.2
  • 9
    • 67349099856 scopus 로고    scopus 로고
    • Osteoprotegerin, vascular calcification and atherosclerosis
    • van C.A. and J. Golledge, Osteoprotegerin, vascular calcification and atherosclerosis. Atherosclerosis 204, 321-329 (2009)
    • (2009) Atherosclerosis , vol.204 , pp. 321-329
    • Van, C.A.1    Golledge, J.2
  • 10
    • 0034711505 scopus 로고    scopus 로고
    • Apoptosis Regulates Human Vascular Calcification in vitro: Evidence for Initiation of Vascular Calcification by Apoptotic Bodies
    • Proudfoot D., J.N. Skepper, L. Hegyi, M.R. Bennett, C.M. Shanahan, and P.L. Weissberg, Apoptosis Regulates Human Vascular Calcification In vitro: Evidence for Initiation of Vascular Calcification by Apoptotic Bodies. Circ Res 87, 1055-1062 (2000)
    • (2000) Circ Res , vol.87 , pp. 1055-1062
    • Proudfoot, D.1    Skepper, J.N.2    Hegyi, L.3    Bennett, M.R.4    Shanahan, C.M.5    Weissberg, P.L.6
  • 11
    • 14644435083 scopus 로고    scopus 로고
    • Impact of inflammation and oxidative stress on vascular calcifications in chronic kidney disease
    • DOI 10.1007/s00467-004-1623-9, IPNA Seventh Symposium on Growth and Development in Children with Chronic Kidney Disease: The Molecular Basis of Skeletal
    • Massy Z. A., C. Maziére, S. Kamel, M. Brazier, G. Choukroun, C. Tribouilloy, M. Slama, M. Andrejak and J. C. Maziére, Impact of inflammation and oxidative stress on vascular calcifications in chronic kidney disease. Pediatr Nephrol 20 (3), 380-382 (2005) (Pubitemid 40309947)
    • (2005) Pediatric Nephrology , vol.20 , Issue.3 SPEC. ISS. , pp. 380-382
    • Massy, Z.A.1    Maziere, C.2    Kamel, S.3    Brazier, M.4    Choukroun, G.5    Tribouilloy, C.6    Slama, M.7    Andrejak, M.8    Maziere, J.C.9
  • 13
    • 33645826282 scopus 로고    scopus 로고
    • Biology of vascular calcification in renal disease
    • Farzaneh-Far A. and C.M. Shanahan, Biology of vascular calcification in renal disease. Nephron Exp Nephrol 101, e134-e138 (2005)
    • (2005) Nephron Exp Nephrol , vol.101
    • Farzaneh-Far, A.1    Shanahan, C.M.2
  • 14
    • 33747428048 scopus 로고    scopus 로고
    • Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification
    • DOI 10.1111/j.1365-2796.2006.01692.x
    • Iyemere V.P., D. Proudfoot, P.L. Weissberg, and C.M. Shanahan, Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification. J Intern Med 260, 192-210 (2006) (Pubitemid 44253633)
    • (2006) Journal of Internal Medicine , vol.260 , Issue.3 , pp. 192-210
    • Iyemere, V.P.1    Proudfoot, D.2    Weissberg, P.L.3    Shanahan, C.M.4
  • 15
    • 33846903357 scopus 로고    scopus 로고
    • Vascular calcification and osteoporosis - From clinical observation towards molecular understanding
    • DOI 10.1007/s00198-006-0282-z
    • Hofbauer L.C., C.C. Brueck, C.M. Shanahan, M. Schoppet, and H. Dobnig, Vascular calcification and osteoporosis-from clinical observation towards molecular understanding. Osteoporos Int 18, 251-259 (2007) (Pubitemid 46233170)
    • (2007) Osteoporosis International , vol.18 , Issue.3 , pp. 251-259
    • Hofbauer, L.C.1    Brueck, C.C.2    Shanahan, C.M.3    Schoppet, M.4    Dobnig, H.5
  • 16
    • 62249090222 scopus 로고    scopus 로고
    • Targeting vascular calcification: Softening-up a hard target
    • Kapustin A. and C.M. Shanahan, Targeting vascular calcification: softening-up a hard target. Curr Opin Pharm 9, 84-89 (2009)
    • (2009) Curr Opin Pharm , vol.9 , pp. 84-89
    • Kapustin, A.1    Shanahan, C.M.2
  • 17
    • 0033883552 scopus 로고    scopus 로고
    • An economic evaluation of sonographic examination of children with suspected appendicitis
    • DOI 10.1053/jpsu.2000.8761
    • Axelrod D.A., S.S. Sonnad, and R.B. Hirschl, An economic evaluation of sonographic examination of children with suspected appendicitis. J Pediatr.Surg 35, 1236-1241 (2000) (Pubitemid 30640218)
    • (2000) Journal of Pediatric Surgery , vol.35 , Issue.8 , pp. 1236-1241
    • Axelrod, D.A.1    Sonnad, S.S.2    Hirschl, R.B.3
  • 18
    • 0030008101 scopus 로고    scopus 로고
    • Electron beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients
    • Braun J., M. Oldendorf, W. Moshage, R. Heidler, E. Zeitler, and F.C. Luft, Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients. Am J Kidney Dis 27, 394-401(1996) (Pubitemid 26075849)
    • (1996) American Journal of Kidney Diseases , vol.27 , Issue.3 , pp. 394-401
    • Braun, J.1    Oldendorf, M.2    Moshage, W.3    Heidler, R.4    Zeitler, E.5    Luft, F.C.6
  • 20
    • 64949130692 scopus 로고    scopus 로고
    • The emerging role of phosphate in vascular calcification
    • Giachelli C.M., The emerging role of phosphate in vascular calcification. Kidney Int 75, 890-897 (2009)
    • (2009) Kidney Int , vol.75 , pp. 890-897
    • Giachelli, C.M.1
  • 23
    • 67349171514 scopus 로고    scopus 로고
    • Phosphate feeding induces arterial medial calcification in uremic mice: Role of serum phosphorus, fibroblast growth factor-23, and osteopontin
    • El-Abbadi M.M., A.S. Pai, E.M. Leaf, H.Y. Yang, B.A. Bartley, K.K. Quan, C.M. Ingalls, H.W. Liao, and C.M. Giachelli, Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin. Kidney Int 75, 1297-1307 (2009)
    • (2009) Kidney Int , vol.75 , pp. 1297-1307
    • El-Abbadi, M.M.1    Pai, A.S.2    Leaf, E.M.3    Yang, H.Y.4    Bartley, B.A.5    Quan, K.K.6    Ingalls, C.M.7    Liao, H.W.8    Giachelli, C.M.9
  • 26
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X., H.Y. Yang, and C.M. Giachelli, Role of the Sodium-Dependent Phosphate Cotransporter, Pit-1, in Vascular Smooth Muscle Cell Calcification. Circ Res 98, 905-912 (2006)
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 27
    • 73649138204 scopus 로고    scopus 로고
    • Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1
    • Festing M.H., M.Y. Speer, H.Y. Yang, and C.M. Giachelli, Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis 47, 858-863 (2009)
    • (2009) Genesis , vol.47 , pp. 858-863
    • Festing, M.H.1    Speer, M.Y.2    Yang, H.Y.3    Giachelli, C.M.4
  • 30
    • 35548972580 scopus 로고    scopus 로고
    • Physiologic and pathologic functions of the NPP nucleotiDe pyrophosphatase/ phosphodiesterase family focusing on NPP1 in calcification
    • Terkeltaub R., Physiologic and pathologic functions of the NPP nucleotiDe pyrophosphatase/ phosphodiesterase family focusing on NPP1 in calcification. Purinergic Signal 2, 371-377 (2006)
    • (2006) Purinergic Signal , vol.2 , pp. 371-377
    • Terkeltaub, R.1
  • 31
    • 0034647482 scopus 로고    scopus 로고
    • Role of the mouse ank gene in control of tissue calcification and arthritis
    • DOI 10.1126/science.289.5477.265
    • Ho A.M., M.D. Johnson, and D.M. Kingsley, Role of the Mouse ank Gene in Control of Tissue Calcification and Arthritis. Science 289, 265-270 (2000) (Pubitemid 30469899)
    • (2000) Science , vol.289 , Issue.5477 , pp. 265-270
    • Ho, A.M.1    Johnson, M.D.2    Kingsley, D.M.3
  • 32
    • 49049083428 scopus 로고    scopus 로고
    • Phosphate and pyrophosphate mediate PKAinduced vascular cell calcification
    • Huang M.S., A.P. Sage, J. Lu, L.L. Demer, and Y. Tintut, Phosphate and pyrophosphate mediate PKAinduced vascular cell calcification. Biochem Biophys Res Commun 374, 553-558 (2008)
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 553-558
    • Huang, M.S.1    Sage, A.P.2    Lu, J.3    Demer, L.L.4    Tintut, Y.5
  • 35
    • 33646799150 scopus 로고    scopus 로고
    • Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway
    • Son B.K., K. Kozaki, K. Iijima, M. Eto, T. Kojima, H. Ota, Y. Senda, K. Maemura, T. Nakano, M. Akishita, and Y. Ouchi, Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway. Circ Res 98, 1024-1031 (2006)
    • (2006) Circ Res , vol.98 , pp. 1024-1031
    • Son, B.K.1    Kozaki, K.2    Iijima, K.3    Eto, M.4    Kojima, T.5    Ota, H.6    Senda, Y.7    Maemura, K.8    Nakano, T.9    Akishita, M.10    Ouchi, Y.11
  • 36
    • 33846103421 scopus 로고    scopus 로고
    • Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells
    • DOI 10.1016/j.ejphar.2006.09.070, PII S0014299906011149
    • Son B.K., K. Kozaki, K. Iijima, M. Eto, T. Nakano, M. Akishita, and Y. Ouchi, Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. Eur J Pharmacol 556, 1-8 (2007) (Pubitemid 46073988)
    • (2007) European Journal of Pharmacology , vol.556 , Issue.1-3 , pp. 1-8
    • Son, B.-K.1    Kozaki, K.2    Iijima, K.3    Eto, M.4    Nakano, T.5    Akishita, M.6    Ouchi, Y.7
  • 39
    • 67349171514 scopus 로고    scopus 로고
    • Phosphate feeding induces arterial medial calcification in uremic mice: Role of serum phosphorus, fibroblast growth factor-23, and osteopontin
    • El-Abbadi M.M., A.S.Pai, E.M.Leaf, H.Y.Yang, B.A.Bartley, K.K.Quan, C.M.Ingalls, H.W.Liao, and C.M.Giachelli, Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin. Kidney Int 75, 1297-1307 (2009)
    • (2009) Kidney Int , vol.75 , pp. 1297-1307
    • El-Abbadi, M.M.1    Pai, A.S.2    Leaf, E.M.3    Yang, H.Y.4    Bartley, B.A.5    Quan, K.K.6    Ingalls, C.M.7    Liao, H.W.8    Giachelli, C.M.9
  • 40
    • 33645742148 scopus 로고    scopus 로고
    • N-3 Fatty Acids Inhibit Vascular Calcification Via the p38-Mitogen-Activated Protein Kinase and Peroxisome Proliferator-Activated Receptor- {gamma} Pathways
    • Abedin M., J. Lim, T.B. Tang, D. Park, L.L. Demer, and Y. Tintut, N-3 Fatty Acids Inhibit Vascular Calcification Via the p38-Mitogen-Activated Protein Kinase and Peroxisome Proliferator-Activated Receptor- {gamma} Pathways. Circ Res 98, 727-729 (2006)
    • (2006) Circ Res , vol.98 , pp. 727-729
    • Abedin, M.1    Lim, J.2    Tang, T.B.3    Park, D.4    Demer, L.L.5    Tintut, Y.6
  • 41
    • 0041819557 scopus 로고    scopus 로고
    • Slowing the progression of vascular calcification in hemodialysis
    • Chertow G.M., Slowing the progression of vascular calcification in hemodialysis. J Am Soc.Nephrol 14, S310-S314 (2003) (Pubitemid 37052396)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.SUPPL. 4
    • Chertow, G.M.1
  • 42
    • 45649084173 scopus 로고    scopus 로고
    • The non-excitable smooth muscle: Calcium signaling and phenotypic switching during vasculardisease
    • House S.J., M. Potier, J. Bisaillon, H.A. Singer, and M. Trebak, The non-excitable smooth muscle: calcium signaling and phenotypic switching during vasculardisease. Pflugers Arch 456, 769-785 (2008)
    • (2008) Pflugers Arch , vol.456 , pp. 769-785
    • House, S.J.1    Potier, M.2    Bisaillon, J.3    Singer, H.A.4    Trebak, M.5
  • 43
    • 0036903683 scopus 로고    scopus 로고
    • 3)- and ryanodine-sensitive calcium stores in rat basilar artery vasomotion
    • DOI 10.1113/jphysiol.2002.027904
    • Haddock R. and C. Hill, Differential activation of ion channels by inositol 1,4,5-trisphosphate (IP3)- and ryanodinesensitive calcium stores in rat basilar artery vasomotion. J Physiol 545, 615-627 (2002) (Pubitemid 36004392)
    • (2002) Journal of Physiology , vol.545 , Issue.2 , pp. 615-627
    • Haddock, R.E.1    Hill, C.E.2
  • 45
    • 9644298257 scopus 로고    scopus 로고
    • Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro
    • DOI 10.1111/j.1523-1755.2004.66015.x
    • Yang H., G. Curinga, and C.M. Giachelli, Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int 66, 2293-2299 (2004) (Pubitemid 41115292)
    • (2004) Kidney International , vol.66 , Issue.6 , pp. 2293-2299
    • Yang, H.1    Curinga, G.2    Giachelli, C.M.3
  • 46
    • 38849119213 scopus 로고    scopus 로고
    • Calcium and cell death: The mitochondrial connection
    • Bernardi P. and A. Rasola, Calcium and cell death: the mitochondrial connection. Subcell Biochem 45, 481-506 (2007)
    • (2007) Subcell Biochem , vol.45 , pp. 481-506
    • Bernardi, P.1    Rasola, A.2
  • 47
    • 77249179705 scopus 로고    scopus 로고
    • Calcium-sensing receptor as a potential modulator of vascular calcification in chronic kidney disease
    • Caudrillier A., R. Mentaverri, M. Brazier, S. Kamel, and Z.A. Massy, Calcium-sensing receptor as a potential modulator of vascular calcification in chronic kidney disease. J Nephrol 23, 17-22 (2010)
    • (2010) J Nephrol , vol.23 , pp. 17-22
    • Caudrillier, A.1    Mentaverri, R.2    Brazier, M.3    Kamel, S.4    Massy, Z.A.5
  • 48
    • 11844269906 scopus 로고    scopus 로고
    • Extracellular calcium sensing receptor: An overview of physiology, pathophysiology and clinical perspectives
    • Msaouel P., A.M. Nixon, A.P. Bramos, E. Baiba, and N.E. Kentarchos, Extracellular calcium sensing receptor: an overview of physiology, pathophysiology and clinical perspectives. In vivo 18, 739-753 (2004)
    • (2004) In Vivo , vol.18 , pp. 739-753
    • Msaouel, P.1    Nixon, A.M.2    Bramos, A.P.3    Baiba, E.4    Kentarchos, N.E.5
  • 51
    • 0035138842 scopus 로고    scopus 로고
    • Extracellular calcium sensing and extracellular calcium signaling
    • Brown E.M. and R.J. MacLeod, Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 81, 239-297 (2001) (Pubitemid 32096177)
    • (2001) Physiological Reviews , vol.81 , Issue.1 , pp. 239-297
    • Brown, E.M.1    Macleod, R.J.2
  • 52
    • 0037184027 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2
    • Xiao G., D. Jiang, R. Gopalakrishnan, and R.T. Franceschi, Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2. J Biol Chem 277, 36181-36187 (2002)
    • (2002) J Biol Chem , vol.277 , pp. 36181-36187
    • Xiao, G.1    Jiang, D.2    Gopalakrishnan, R.3    Franceschi, R.T.4
  • 53
    • 0037441529 scopus 로고    scopus 로고
    • Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways
    • DOI 10.1002/jcb.10369
    • Franceschi R.T. and G. Xiao, Regulation of the osteoblastspecific transcription factor, Runx2: responsiveness to multiple signal transduction pathways. J Cell Biochem 88, 446-454 (2003) (Pubitemid 36158266)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.3 , pp. 446-454
    • Franceschi, R.T.1    Xiao, G.2
  • 54
    • 66949118241 scopus 로고    scopus 로고
    • Role of the MAPK/ERK pathway in valvular interstitial cell calcification
    • Gu X.X. and K.S. Masters, Role of the MAPK/ERK pathway in valvular interstitial cell calcification. Am J Physiol -Heart and Circulatory Physiol 296, H1748-H1757 (2009)
    • (2009) Am J Physiol -Heart and Circulatory Physiol , vol.296
    • Gu, X.X.1    Masters, K.S.2
  • 55
    • 57649200121 scopus 로고    scopus 로고
    • Extracellular Calcium-Sensing Receptor Mediated Signalling is Involved in Human Vascular Smooth Muscle Cell Proliferation and Apoptosis
    • Molostvov G., S. Fletcher, R. Bland, and D. Zehnder, Extracellular Calcium-Sensing Receptor Mediated Signalling is Involved in Human Vascular Smooth Muscle Cell Proliferation and Apoptosis. Cell Physiol Biochem 22, 413-422 (2008)
    • (2008) Cell Physiol Biochem , vol.22 , pp. 413-422
    • Molostvov, G.1    Fletcher, S.2    Bland, R.3    Zehnder, D.4
  • 56
    • 21844438223 scopus 로고    scopus 로고
    • Proinflammatory vascular calcification
    • DOI 10.1161/01.RES.0000172407.20974.e5
    • Bostrom K., Proinflammatory Vascular Calcification. Circ Res 96, 1219-1220 (2005) (Pubitemid 40962098)
    • (2005) Circulation Research , vol.96 , Issue.12 , pp. 1219-1220
    • Bostrom, K.1
  • 58
    • 74249083865 scopus 로고    scopus 로고
    • Effect of antiplatelet therapy on inflammatory markers in atherothrombotic patients
    • Muhlestein J.B., Effect of antiplatelet therapy on inflammatory markers in atherothrombotic patients. Thromb Haemost 103, 71-82 (2010)
    • (2010) Thromb Haemost , vol.103 , pp. 71-82
    • Muhlestein, J.B.1
  • 60
    • 0034700234 scopus 로고    scopus 로고
    • Tumor necrosis factor-{Alpha} promotes in vitro calcification of vascular cells via the cAMP pathway
    • Tintut Y., J. Patel, F. Parhami, and L.L. Demer, Tumor Necrosis Factor-{alpha} Promotes In vitro Calcification of Vascular Cells via the cAMP Pathway. Circulation 102, 2636-2642 (2000)
    • (2000) Circulation , vol.102 , pp. 2636-2642
    • Tintut, Y.1    Patel, J.2    Parhami, F.3    Demer, L.L.4
  • 61
    • 41549125017 scopus 로고    scopus 로고
    • Adiponectin antagonizes stimulatory effect of tumor necrosis factor-α on vascular smooth muscle cell calcification: Regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5′-monophosphate-activated protein kinase
    • DOI 10.1210/en.2007-1021
    • Son B.K., M. Akishita, K. Iijima, K. Kozaki, K. Maemura, M. Eto, and Y. Ouchi, Adiponectin antagonizes stimulatory effect of tumor necrosis factoralpha on vascular smooth muscle cell calcification: regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5'-monophosphateactivated protein kinase. Endocrinology 149, 1646-1653 (2008) (Pubitemid 351468314)
    • (2008) Endocrinology , vol.149 , Issue.4 , pp. 1646-1653
    • Son, B.-K.1    Akishita, M.2    Iijima, K.3    Kozaki, K.4    Maemura, K.5    Eto, M.6    Ouchi, Y.7
  • 62
    • 72949101767 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction
    • Lee H.L., K.M. Woo, H.M. Ryoo, and J.H. Baek, Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction. Biochem Biophys Res Commun 391, 1087-1092 (2010)
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1087-1092
    • Lee, H.L.1    Woo, K.M.2    Ryoo, H.M.3    Baek, J.H.4
  • 64
    • 77149122729 scopus 로고    scopus 로고
    • Inflammation and the osteogenic regulation of vascular calcification: A review and perspective
    • Shao J.S., S.L. Cheng, J. Sadhu, and D.A. Towler, Inflammation and the osteogenic regulation of vascular calcification: a review and perspective. Hypertension 55, 579-592 (2010)
    • (2010) Hypertension , vol.55 , pp. 579-592
    • Shao, J.S.1    Cheng, S.L.2    Sadhu, J.3    Towler, D.A.4
  • 65
    • 0034051068 scopus 로고    scopus 로고
    • Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
    • DOI 10.1146/annurev.med.51.1.245
    • Ershler W.B. and E.T. Keller, Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 51, 245-270 (2000) (Pubitemid 30216036)
    • (2000) Annual Review of Medicine , vol.51 , pp. 245-270
    • Ershler, W.B.1    Keller, E.T.2
  • 66
    • 47249157776 scopus 로고    scopus 로고
    • Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factorRunx2 by AKT signaling
    • Byon C.H., A. Javed, Q. Dai, J.C. Kappes, T.L. Clemens, V.M. rley-Usmar, J.M. McDonald, and Y.B. Chen, Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factorRunx2 by AKT signaling. J Biol Chem 283, 15319-15327 (2008)
    • (2008) J Biol Chem , vol.283 , pp. 15319-15327
    • Byon, C.H.1    Javed, A.2    Dai, Q.3    Kappes, J.C.4    Clemens, T.L.5    Rley-Usmar, V.M.6    McDonald, J.M.7    Chen, Y.B.8
  • 67
    • 0036042240 scopus 로고    scopus 로고
    • Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia
    • DOI 10.1159/000065203
    • Drueke T.B. and Z.A. Massy, Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia. Blood Purif 20, 494-497 (2002) (Pubitemid 35007570)
    • (2002) Blood Purification , vol.20 , Issue.5 , pp. 494-497
    • Drueke, T.B.1    Massy, Z.A.2
  • 68
    • 41549158281 scopus 로고    scopus 로고
    • Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase
    • DOI 10.1210/en.2007-1544
    • Shi X.Y., F.F. Hou, H.X. Niu, G.B. Wang, D. Xie, Z.J. Guo, Z.M. Zhou, F. Yang, J.W. Tian, and X. Zhang, Advanced Oxidation Protein Products Promote Inflammation in Diabetic Kidney through Activation of Renal NicotinamiDe Adenine DinucleotiDe Phosphate Oxidase. Endocrinology 149, 1829-1839 (2008) (Pubitemid 351468323)
    • (2008) Endocrinology , vol.149 , Issue.4 , pp. 1829-1839
    • Xiao, Y.S.1    Fan, F.H.2    Hong, X.N.3    Guo, B.W.4    Xie, D.5    Zhi, J.G.6    Zhan, M.Z.7    Yang, F.8    Jian, W.T.9    Zhang, X.10
  • 70
    • 67651160384 scopus 로고    scopus 로고
    • Advanced oxidation protein products induce vascular calcification by promoting osteoblastic transdifferentiation of smooth muscle cells via oxidative stress and ERK pathway
    • You H., H. Yang, Q. Zhu, M. Li, J. Xue, Y. Gu, S. Lin, and F. Ding, Advanced oxidation protein products induce vascular calcification by promoting osteoblastic transdifferentiation of smooth muscle cells via oxidative stress and ERK pathway. Ren Fail 31, 313-319 (2009)
    • (2009) Ren Fail , vol.31 , pp. 313-319
    • You, H.1    Yang, H.2    Zhu, Q.3    Li, M.4    Xue, J.5    Gu, Y.6    Lin, S.7    Ding, F.8
  • 71
    • 67649447069 scopus 로고    scopus 로고
    • Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK
    • Tanikawa T., Y. Okada, R. Tanikawa, and Y. Tanaka, Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK. J Vasc Res 46, 572-580 (2009)
    • (2009) J Vasc Res , vol.46 , pp. 572-580
    • Tanikawa, T.1    Okada, Y.2    Tanikawa, R.3    Tanaka, Y.4
  • 72
    • 51849153694 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein acts synergistically with betaglycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells
    • Bear M., M. Butcher, and S.G. Shaughnessy, Oxidized low-density lipoprotein acts synergistically with betaglycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells. J Cell Biochem 105, 185-193 (2008)
    • (2008) J Cell Biochem , vol.105 , pp. 185-193
    • Bear, M.1    Butcher, M.2    Shaughnessy, S.G.3
  • 73
    • 33747625689 scopus 로고    scopus 로고
    • Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress
    • DOI 10.1161/01.RES.0000233315.38086.bc, PII 0000301220060721000009
    • Matthews C., I. Gorenne, S. Scott, N. Figg, P. Kirkpatrick, A. Ritchie, M. Goddard, and M. Bennett, Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress. Circ Res 99, 156-164 (2006) (Pubitemid 44297039)
    • (2006) Circulation Research , vol.99 , Issue.2 , pp. 156-164
    • Matthews, C.1    Gorenne, I.2    Scott, S.3    Figg, N.4    Kirkpatrick, P.5    Ritchie, A.6    Goddard, M.7    Bennett, M.8
  • 74
    • 77953023624 scopus 로고    scopus 로고
    • Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging
    • Ragnauth C.D., D.T. Warren, Y. Liu, R. McNair, T. Tajsic, N. Figg, R. Shroff, J. Skepper, and C.M. Shanahan, Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging. Circulation 121(20), 2200-2210 (2010)
    • (2010) Circulation , vol.121 , Issue.20 , pp. 2200-2210
    • Ragnauth, C.D.1    Warren, D.T.2    Liu, Y.3    McNair, R.4    Tajsic, T.5    Figg, N.6    Shroff, R.7    Skepper, J.8    Shanahan, C.M.9
  • 75
    • 33748164460 scopus 로고    scopus 로고
    • Vascular smooth muscle cell senescence in atherosclerosis
    • DOI 10.1016/j.cardiores.2006.06.004, PII S0008636306002550
    • Gorenne I., M. Kavurma, S. Scott, and M. Bennett, Vascular smooth muscle cell senescence in atherosclerosis. Cardiovasc Res 72, 9-17 (2006) (Pubitemid 44310633)
    • (2006) Cardiovascular Research , vol.72 , Issue.1 , pp. 9-17
    • Gorenne, I.1    Kavurma, M.2    Scott, S.3    Bennett, M.4
  • 78
    • 0037422592 scopus 로고    scopus 로고
    • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part I: Aging arteries: A "set up" for vascular disease
    • DOI 10.1161/01.CIR.0000048892.83521.58
    • Lakatta E.G. and D. Levy, Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A "Set Up" for Vascular Disease. Circulation 107, 139-146 (2003) (Pubitemid 36070946)
    • (2003) Circulation , vol.107 , Issue.1 , pp. 139-146
    • Lakatta, E.G.1    Levy, D.2
  • 79
    • 77950145765 scopus 로고    scopus 로고
    • Increased expression of inflammation cytokines in senescent vascular smooth muscle cells by balloon catheter denudation is associated with NF-[kappa]B pathway
    • Zongjie Q., L. Qiu, X. Chuanshi, T. Shan, and B. Yunfei, Increased expression of inflammation cytokines in senescent vascular smooth muscle cells by balloon catheter denudation is associated with NF-[kappa]B pathway. J Med Coll of PLA 23, 324-335 (2008)
    • (2008) J Med Coll of PLA , vol.23 , pp. 324-335
    • Zongjie, Q.1    Qiu, L.2    Chuanshi, X.3    Shan, T.4    Yunfei, B.5
  • 80
    • 0242361641 scopus 로고    scopus 로고
    • Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis
    • DOI 10.1161/01.CIR.0000093274.82929.22
    • Minamino T., T. Yoshida, K. Tateno, H. Miyauchi, Y. Zou, H. Toko, and I. Komuro, Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 108, 2264-2269(2003) (Pubitemid 37363045)
    • (2003) Circulation , vol.108 , Issue.18 , pp. 2264-2269
    • Minamino, T.1    Yoshida, T.2    Tateno, K.3    Miyauchi, H.4    Zou, Y.5    Toko, H.6    Komuro, I.7
  • 81
    • 0037150157 scopus 로고    scopus 로고
    • Functional inhibition of Ras by S-trans, trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein e knockout mice
    • DOI 10.1161/01.CIR.0000016065.90068.96
    • George J., A. Afek, P. Keren, I. Herz, I. Goldberg, R. Haklai, Y. Kloog, and G. Keren, Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice. Circulation 105, 2416-2422 (2002) (Pubitemid 34556395)
    • (2002) Circulation , vol.105 , Issue.20 , pp. 2416-2422
    • George, J.1    Afek, A.2    Keren, P.3    Herz, I.4    Goldberg, I.5    Haklai, R.6    Kloog, Y.7    Keren, G.8
  • 82
    • 48649103092 scopus 로고    scopus 로고
    • Cytokine loops driving senescence
    • Bartek J., Z. Hodny, and J. Lukas, Cytokine loops driving senescence. Nat.Cell Biol 10, 887-889 (2008)
    • (2008) Nat.Cell Biol , vol.10 , pp. 887-889
    • Bartek, J.1    Hodny, Z.2    Lukas, J.3
  • 83
    • 0031730268 scopus 로고    scopus 로고
    • Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo
    • Grainger D.J., J.C. Metcalfe, A.A. Grace, and D.E. Mosedale, Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo. J Cell Sci 111 ( Pt 19), 2977-2988 (1998) (Pubitemid 28495204)
    • (1998) Journal of Cell Science , vol.111 , Issue.19 , pp. 2977-2988
    • Grainger, D.J.1    Metcalfe, J.C.2    Grace, A.A.3    Mosedale, D.E.4
  • 84
    • 0344924879 scopus 로고    scopus 로고
    • Interaction of Smad3 and SRF-associated complex mediates TGF-beta1 signals to regulate SM22 transcription during myofibroblast differentiation
    • DOI 10.1016/j.yjmcc.2003.09.002
    • Qiu P., X.H. Feng, and L. Li, Interaction of Smad3 and SRF-associated complex mediates TGF-[beta]1 signals to regulate SM22 transcription during myofibroblast differentiation. J Mol Cell Cardiol 35, 1407-1420 (2003) (Pubitemid 37491184)
    • (2003) Journal of Molecular and Cellular Cardiology , vol.35 , Issue.12 , pp. 1407-1420
    • Qiu, P.1    Feng, X.-H.2    Li, L.3
  • 86
    • 57349106562 scopus 로고    scopus 로고
    • Uncoupling of ER-mitochondrial calcium communication by transforming growth factor-beta
    • Pacher P., K. Sharma, G. Csordas, Y. Zhu, and G. Hajnoczky, Uncoupling of ER-mitochondrial calcium communication by transforming growth factor-beta. Am J Physiol Renal Physiol295, F1303-F1312 (2008)
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Pacher, P.1    Sharma, K.2    Csordas, G.3    Zhu, Y.4    Hajnoczky, G.5
  • 87
    • 38849207866 scopus 로고    scopus 로고
    • Nitric oxide regulates vascular calcification by interfering with TGF-beta signalling
    • DOI 10.1093/cvr/cvm049
    • Kanno Y., T. Into, C.J. Lowenstein, and K. Matsushita, Nitric oxiDe regulates vascular calcification by interfering with TGF- signalling. Cardiovasc Res 77, 221-230 (2008) (Pubitemid 351195162)
    • (2008) Cardiovascular Research , vol.77 , Issue.1 , pp. 221-230
    • Kanno, Y.1    Into, T.2    Lowenstein, C.J.3    Matsushita, K.4
  • 88
    • 70349135494 scopus 로고    scopus 로고
    • Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signalregulated kinase 1/2
    • Yang X., X. Meng, X. Su, D.C. Mauchley, L. Ao, J.C. Cleveland, Jr., and D.A.Fullerton, Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signalregulated kinase 1/2. J Thorac Cardiovasc Surg 138, 1008-1015 (2009)
    • (2009) J Thorac Cardiovasc Surg , vol.138 , pp. 1008-1015
    • Yang, X.1    Meng, X.2    Su, X.3    Mauchley, D.C.4    Ao, L.5    Cleveland Jr., J.C.6    Fullerton, D.A.7
  • 89
    • 22744434737 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in vascular calcification
    • DOI 10.1161/01.RES.00000175571.53833.6c
    • Hruska K.A., S. Mathew, and G. Saab, Bone Morphogenetic Proteins in Vascular Calcification. Circ Res 97, 105-114 (2005) (Pubitemid 41033466)
    • (2005) Circulation Research , vol.97 , Issue.2 , pp. 105-114
    • Hruska, K.A.1    Mathew, S.2    Saab, G.3
  • 90
    • 33845450617 scopus 로고    scopus 로고
    • Bone morphogenetic protein-induced Msx1 and Msx2 inhibit myocardin-dependent smooth muscle gene transcription
    • DOI 10.1128/MCB.00759-06
    • Hayashi K., S. Nakamura, W. Nishida, and K. Sobue, Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription. Mol Cell Biol 26, 9456-9470 (2006) (Pubitemid 44904438)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.24 , pp. 9456-9470
    • Hayashi, K.1    Nakamura, S.2    Nishida, W.3    Sobue, K.4
  • 92
    • 0242664267 scopus 로고    scopus 로고
    • Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors
    • DOI 10.1074/jbc.M306972200
    • Cheng S.L., J.S. Shao, N. Charlton-Kachigian, A.P. Loewy, and D.A. Towler, MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem 278, 45969-45977 (2003) (Pubitemid 37432744)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.46 , pp. 45969-45977
    • Cheng, S.-L.1    Shao, J.-S.2    Charlton-Kachigian, N.3    Loewy, A.P.4    Towler, D.A.5
  • 93
    • 0043136513 scopus 로고    scopus 로고
    • Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-α in normal and osteoarthritic chondrocytes
    • Fukui N., Y. Zhu, W.J. Maloney, J. Clohisy, and L.J. Sandell, Stimulation of BMP-2 expression by proinflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes. J Bone Joint Surg Am 85-A Suppl 3, 59-66 (2003) (Pubitemid 36951118)
    • (2003) Journal of Bone and Joint Surgery - Series A , vol.85 , Issue.SUPPL. 3 , pp. 59-66
    • Fukui, N.1    Zhu, Y.2    Maloney, W.J.3    Clohisy, J.4    Sandell, L.J.5
  • 94
    • 0030929793 scopus 로고    scopus 로고
    • Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation: A possible explanation for the paradox of arterial calcification in osteoporotic patients
    • Parhami F., A.D. Morrow, J. Balucan, N. Leitinger, A.D. Watson, Y. Tintut, J.A. Berliner, and L.L. Demer, Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients. Arterioscler Thromb Vasc Biol 17, 680-687 (1997) (Pubitemid 27169128)
    • (1997) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.17 , Issue.4 , pp. 680-687
    • Parhami, F.1    Morrow, A.D.2    Balucan, J.3    Leitinger, N.4    Watson, A.D.5    Tintut, Y.6    Berliner, J.A.7    Demer, L.L.8
  • 95
    • 40949158527 scopus 로고    scopus 로고
    • BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells
    • Li X., H.Y. Yang, and C.M. Giachelli, BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis 199, 271-277 (2008)
    • (2008) Atherosclerosis , vol.199 , pp. 271-277
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 96
    • 79959621543 scopus 로고    scopus 로고
    • Abstract 3724: Reactive oxygen species mediate bone morphogenetic protein 2 induced calcification of human coronary artery smooth muscle cells by increasing RUNX2 expression
    • Liberman M., G. Michas, A. Verhovez, B.A. Maron, and J.A. Leopold, Abstract 3724: Reactive Oxygen Species Mediate Bone Morphogenetic Protein 2 Induced Calcification of Human Coronary Artery Smooth Muscle Cells by Increasing RUNX2 Expression. Circulation 118, S-475 (2008)
    • (2008) Circulation , vol.118
    • Liberman, M.1    Michas, G.2    Verhovez, A.3    Maron, B.A.4    Leopold, J.A.5
  • 97
    • 0242443189 scopus 로고    scopus 로고
    • Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells
    • DOI 10.1002/jcb.10669
    • Zebboudj A.F., V. Shin, and K. Bostrom, Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells. J Cell Biochem 90, 756-765 (2003) (Pubitemid 37392466)
    • (2003) Journal of Cellular Biochemistry , vol.90 , Issue.4 , pp. 756-765
    • Zebboudj, A.F.1    Shin, V.2    Bostrom, K.3
  • 99
    • 42249089502 scopus 로고    scopus 로고
    • Arterial calcification: A tumor necrosis factor-alpha mediated vascular Wnt-opathy
    • DOI 10.1016/j.trsl.2007.12.005, PII S1931524407003398
    • Al-Aly Z., Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy. Transl Res 151, 233-239 (2008) (Pubitemid 351545863)
    • (2008) Translational Research , vol.151 , Issue.5 , pp. 233-239
    • Al-Aly, Z.1
  • 100
    • 33847367723 scopus 로고    scopus 로고
    • Wnt signalling: Variety at the core
    • DOI 10.1242/jcs.03363
    • Hoppler S. and C.L. Kavanagh, Wnt signalling: variety at the core. J Cell Sci 120, 385-393 (2007) (Pubitemid 46332502)
    • (2007) Journal of Cell Science , vol.120 , Issue.3 , pp. 385-393
    • Hoppler, S.P.1    Kavanagh, C.L.2
  • 102
    • 55749102279 scopus 로고    scopus 로고
    • Alternative wnt signaling is initiated by distinct receptors
    • van A.R., A. Mikels, and R. Nusse, Alternative wnt signaling is initiated by distinct receptors. Sci Signal 1, re9 (2008)
    • (2008) Sci Signal , vol.1
    • Van, A.R.1    Mikels, A.2    Nusse, R.3
  • 103
    • 50649109669 scopus 로고    scopus 로고
    • Msx2 exerts bone anabolism via canonical Wnt signaling
    • Cheng S.L., J.S. Shao, J. Cai, O.L. Sierra, and D.A. Towler, Msx2 exerts bone anabolism via canonical Wnt signaling. J Biol Chem 283, 20505-20522 (2008)
    • (2008) J Biol Chem , vol.283 , pp. 20505-20522
    • Cheng, S.L.1    Shao, J.S.2    Cai, J.3    Sierra, O.L.4    Towler, D.A.5
  • 107
    • 34748827997 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes: Potential relevance to vascular disease?
    • DOI 10.1161/CIRCRESAHA.107.156372
    • Kirton J.P., N.J. Crofts, S.J. George, K. Brennan, and A.E. Canfield, Wnt/beta-catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes: potential relevance to vascular disease? Circ Res 101, 581-589 (2007) (Pubitemid 351325875)
    • (2007) Circulation Research , vol.101 , Issue.6 , pp. 581-589
    • Kirton, J.P.1    Crofts, N.J.2    George, S.J.3    Brennan, K.4    Canfield, A.E.5
  • 110
    • 77952919493 scopus 로고    scopus 로고
    • Notch and TGF{beta} signaling pathways cooperatively regulate vascular smooth muscle cell differentiation
    • Tang Y., S. Urs, J. Boucher, T. Bernaiche, D. Venkatesh, D.B. Spicer, C.P. Vary, and L. Liaw, Notch and TGF{beta} signaling pathways cooperatively regulate vascular smooth muscle cell differentiation. J Biol Chem 285(23), 17556-63 (2010).
    • (2010) J Biol Chem , vol.285 , Issue.23 , pp. 17556-17563
    • Tang, Y.1    Urs, S.2    Boucher, J.3    Bernaiche, T.4    Venkatesh, D.5    Spicer, D.B.6    Vary, C.P.7    Liaw, L.8
  • 112
    • 0041856097 scopus 로고    scopus 로고
    • Phosphorylation by glycogen synthase kinase-3beta down-regulates Notch activity, a link for Notch and Wnt pathways
    • DOI 10.1074/jbc.M304001200
    • Espinosa L., J. Ingles-Esteve, C. Aguilera, and A. Bigas, Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. J Biol Chem 278, 32227-32235 (2003) (Pubitemid 37048415)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 32227-32235
    • Espinosa, L.1    Ingles-Esteve, J.2    Aguilera, C.3    Bigas, A.4
  • 113
    • 54749138371 scopus 로고    scopus 로고
    • Notch signaling in cardiovascular disease and calcification
    • Rusanescu G., R. Weissleder, and E. Aikawa, Notch signaling in cardiovascular disease and calcification. Curr Cardiol Rev 4, 148-156 (2008)
    • (2008) Curr Cardiol Rev , vol.4 , pp. 148-156
    • Rusanescu, G.1    Weissleder, R.2    Aikawa, E.3
  • 115
    • 33746485180 scopus 로고    scopus 로고
    • Smooth muscle α-actin is a direct target of Notch/CSL
    • DOI 10.1161/01.RES.0000229683.81357.26, PII 0000301220060623000006
    • Noseda M., Y. Fu, K. Niessen, F. Wong, L. Chang, G. McLean, and A. Karsan, Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circ Res 98, 1468-1470 (2006) (Pubitemid 44297068)
    • (2006) Circulation Research , vol.98 , Issue.12 , pp. 1468-1470
    • Noseda, M.1    Fu, Y.2    Niessen, K.3    Wong, F.4    Chang, L.5    McLean, G.6    Karsan, A.7
  • 117
    • 35649000861 scopus 로고    scopus 로고
    • Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-κB drives crosstalk
    • DOI 10.1242/jcs.007872
    • Clement N., M. Gueguen, M. Glorian, R. Blaise, M. Andreani, C. Brou, P. Bausero, and I. Limon, Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk. J Cell Sci 120, 3352-3361 (2007) (Pubitemid 350028343)
    • (2007) Journal of Cell Science , vol.120 , Issue.19 , pp. 3352-3361
    • Clement, N.1    Gueguen, M.2    Glorian, M.3    Blaise, R.4    Andreani, M.5    Brou, C.6    Bausero, P.7    Limon, I.8
  • 118
    • 41449107073 scopus 로고    scopus 로고
    • Hairy-related transcription factors inhibit notch-induced smooth muscle α-actin expression by interfering with notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site
    • DOI 10.1161/CIRCRESAHA.107.165134
    • Tang Y., S. Urs, and L. Liaw, Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. Circ Res 102, 661-668 (2008) (Pubitemid 351457858)
    • (2008) Circulation Research , vol.102 , Issue.6 , pp. 661-668
    • Tang, Y.1    Urs, S.2    Liaw, L.3
  • 119
    • 67650334134 scopus 로고    scopus 로고
    • Notch Signaling Induces Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells Role of Msx2 Gene Induction via Notch-RBP-Jk Signaling
    • Shimizu T., T. Tanaka, T. Iso, H. Doi, H. Sato, K. Kawai-Kowase, M. Arai, and M. Kurabayashi, Notch Signaling Induces Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells Role of Msx2 Gene Induction via Notch-RBP-Jk Signaling. Arterioscler Thromb Vasc Biol 29, 1104-1111 (2009)
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1104-1111
    • Shimizu, T.1    Tanaka, T.2    Iso, T.3    Doi, H.4    Sato, H.5    Kawai-Kowase, K.6    Arai, M.7    Kurabayashi, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.