Wnt/β-catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes: Potential relevance to vascular disease?

Circulation Research

Volumn 101, Issue 6, 2007, Pages 581-589

  Kirton, John Paul ^a,b   Crofts, Nicola J ^a,b   George, Sarah J ^c   Brennan, Keith ^a,b   Canfield, Ann E ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Chondrogenesis; Differentiation; Pericytes; Vascular disease; Wnt signaling

Indexed keywords

BETA CATENIN; CALCIUM ION; COLLAGEN TYPE 2; FRIZZLED PROTEIN; GLYCOSAMINOGLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 10; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 3; SECRETED FRIZZLED RELATED PROTEIN 4; SECRETED FRIZZLED RELATED PROTEIN 7; SECRETED FRIZZLED RELATED PROTEIN 8; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN; AGGRECAN; HIGH MOBILITY GROUP PROTEIN; LITHIUM CHLORIDE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MESSENGER RNA; PROTEOGLYCAN; SOX-9 TRANSCRIPTION FACTOR; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR; WNT3 PROTEIN;

ADENOVIRUS; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; GENETIC TRANSCRIPTION; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CATTLE; CELL CULTURE; DRUG EFFECT; GENETIC TRANSDUCTION; GENETICS; LIPID METABOLISM; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; VASCULAR DISEASE;

ADIPOGENESIS; AGGRECANS; ANIMALS; BETA CATENIN; CATTLE; CELLS, CULTURED; CHONDROGENESIS; COLLAGEN TYPE II; FRIZZLED RECEPTORS; GLYCOSAMINOGLYCANS; HIGH MOBILITY GROUP PROTEINS; LDL-RECEPTOR RELATED PROTEINS; LIPID METABOLISM; LITHIUM CHLORIDE; PERICYTES; PROTEOGLYCANS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSDUCTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA3; VASCULAR DISEASES; WNT PROTEINS;

EID: 34748827997     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.107.156372     Document Type: Article

References (42)