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Volumn 337, Issue 2, 2011, Pages 335-349

A view on imaging in drug research and development for respiratory diseases

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 11; COPPER 64; DEXAMETHASONE; FLUORINE 18; FLUORODEOXYGLUCOSE F 18; INDIUM 111; SULESOMAB TC 99M; TECHNETIUM 99M; XENON 133;

EID: 79954997159     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.172635     Document Type: Article
Times cited : (13)

References (142)
  • 1
    • 0032590018 scopus 로고    scopus 로고
    • Regional VA/Q ratios in man using 133Xe and single photon emission computed tomography (SPECT) corrected for attenuation
    • Almquist H, Jonson B, Palmer J, Valind S, and Wollmer P (1999) Regional VA/Q ratios in man using 133Xe and single photon emission computed tomography (SPECT) corrected for attenuation. Clin Physiol 19:475-481.
    • (1999) Clin Physiol , vol.19 , pp. 475-481
    • Almquist, H.1    Jonson, B.2    Palmer, J.3    Valind, S.4    Wollmer, P.5
  • 2
    • 22244472036 scopus 로고    scopus 로고
    • Pulmonary embolism: Comprehensive evaluation with MR ventilation and perfusion scanning with hyperpolarized helium-3, arterial spin tagging, and contrast-enhanced MRA
    • DOI 10.1097/01.RVI.0000162416.64412.FC
    • Altes TA, Mai VM, Munger TM, Brookeman JR, and Hagspiel KD (2005) Pulmonary embolism: Comprehensive evaluation with MR ventilation and perfusion scanning with hyperpolarized helium-3, arterial spin tagging, and contrast-enhanced MRA. J Vasc Interv Radiol 16:999-1005. (Pubitemid 40993522)
    • (2005) Journal of Vascular and Interventional Radiology , vol.16 , Issue.7 , pp. 999-1005
    • Altes, T.A.1    Mai, V.M.2    Munger, T.M.3    Brookeman, J.R.4    Hagspiel, K.D.5
  • 5
    • 79952265754 scopus 로고    scopus 로고
    • Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI
    • doi: 10.1002/jmri.22476
    • Babin AL, Cannet C, Gérard C, Wyss D, Page CP, and Beckmann N (2011) Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI. J Magn Reson Imaging doi: 10.1002/jmri.22476
    • (2011) J Magn Reson Imaging
    • Babin, A.L.1    Cannet, C.2    Gérard, C.3    Wyss, D.4    Page, C.P.5    Beckmann, N.6
  • 6
    • 73649083320 scopus 로고    scopus 로고
    • Lung perfusion imaging in small animals using 4D micro-CT at heartbeat temporal resolution
    • Badea CT, Johnston SM, Subashi E, Qi Y, Hedlund LW, and Johnson GA (2010) Lung perfusion imaging in small animals using 4D micro-CT at heartbeat temporal resolution. Med Phys 37:54-62.
    • (2010) Med Phys , vol.37 , pp. 54-62
    • Badea, C.T.1    Johnston, S.M.2    Subashi, E.3    Qi, Y.4    Hedlund, L.W.5    Johnson, G.A.6
  • 9
  • 12
    • 3543085760 scopus 로고    scopus 로고
    • Proton MRI of lung parenchyma reflects allergen-induced airway remodeling and endotoxin-aroused hyporesponsiveness: A step toward ventilation studies in spontaneously breathing rats
    • DOI 10.1002/mrm.20127
    • Beckmann N, Cannet C, Zurbruegg S, Rudin M, and Tigani B (2004) Proton MRI of lung parenchyma reflects allergen-induced airway remodeling and endotoxinaroused hyporesponsiveness: A step toward ventilation studies in spontaneously breathing rats. Magn Reson Med 52:258-268. (Pubitemid 39025269)
    • (2004) Magnetic Resonance in Medicine , vol.52 , Issue.2 , pp. 258-268
    • Beckmann, N.1    Cannet, C.2    Zurbruegg, S.3    Rudin, M.4    Tigani, B.5
  • 15
    • 0035163218 scopus 로고    scopus 로고
    • Pulmonary edema induced by allergen challenge in the rat: Noninvasive assessment by magnetic resonance imaging
    • DOI 10.1002/1522-2594(200101)45:1<88::AID-MRM1013>3.0.CO;2-N
    • Beckmann N, Tigani B, Ekatodramis D, Borer R, Mazzoni L, and Fozard JR (2001a) Pulmonary edema induced by allergen challenge in the rat: Noninvasive assessment by magnetic resonance imaging. Magn Reson Med 45:88-95. (Pubitemid 32044269)
    • (2001) Magnetic Resonance in Medicine , vol.45 , Issue.1 , pp. 88-95
    • Beckmann, N.1    Tigani, B.2    Ekatodramis, D.3    Borer, R.4    Mazzoni, L.5    Fozard, J.R.6
  • 16
    • 0034877084 scopus 로고    scopus 로고
    • MRI of lung parenchyma in rats and mice using a gradient-echo sequence
    • DOI 10.1002/nbm.706
    • Beckmann N, Tigani B, Mazzoni L, and Fozard JR (2001b) MRI of lung parenchyma in rats and mice using a gradient-echo sequence. NMR Biomed 14:297-306. (Pubitemid 32782843)
    • (2001) NMR in Biomedicine , vol.14 , Issue.5 , pp. 297-306
    • Beckmann, N.1    Tigani, B.2    Mazzoni, L.3    Fozard, J.R.4
  • 18
    • 40949144005 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Physiologic tests, quantitative CT indexes, and CT visual scores as predictors of mortality
    • Best AC, Meng J, Lynch AM, Bozic CM, Miller D, Grunwald GK, and Lynch DA (2008) Idiopathic pulmonary fibrosis: Physiologic tests, quantitative CT indexes, and CT visual scores as predictors of mortality. Radiology 246:935-940.
    • (2008) Radiology , vol.246 , pp. 935-940
    • Best, A.C.1    Meng, J.2    Lynch, A.M.3    Bozic, C.M.4    Miller, D.5    Grunwald, G.K.6    Lynch, D.A.7
  • 19
    • 69249211282 scopus 로고    scopus 로고
    • Imaging the molecular signatures of apoptosis and injury with radiolabeled annexin V
    • Blankenberg FG (2009) Imaging the molecular signatures of apoptosis and injury with radiolabeled annexin V. Proc Am Thorac Soc 6:469-476.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 469-476
    • Blankenberg, F.G.1
  • 20
    • 77952834551 scopus 로고    scopus 로고
    • ENaCmediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration
    • Blé FX, Cannet C, Collingwood S, Danahay H, and Beckmann N (2010) ENaCmediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration. Br J Pharmacol 160:1008-1015.
    • (2010) Br J Pharmacol , vol.160 , pp. 1008-1015
    • Blé, F.X.1    Cannet, C.2    Collingwood, S.3    Danahay, H.4    Beckmann, N.5
  • 26
    • 34047166052 scopus 로고    scopus 로고
    • Airway surface dehydration in cystic fibrosis: Pathogenesis and therapy
    • DOI 10.1146/annurev.med.58.071905.105316
    • Boucher RC (2007) Airway surface dehydration in cystic fibrosis: Pathogenesis and therapy. Annu Rev Med 58:157-170. (Pubitemid 46706507)
    • (2007) Annual Review of Medicine , vol.58 , pp. 157-170
    • Boucher, R.C.1
  • 28
    • 7544251114 scopus 로고    scopus 로고
    • Dynamic lung morphology of methacholine-induced heterogeneous bronchoconstriction
    • DOI 10.1002/mrm.20251
    • Chen BT and Johnson GA (2004) Dynamic lung morphology of methacholine-induced heterogeneous bronchoconstriction. Magn Reson Med 52:1080-1086. (Pubitemid 39453281)
    • (2004) Magnetic Resonance in Medicine , vol.52 , Issue.5 , pp. 1080-1086
    • Chen, B.T.1    Johnson, G.A.2
  • 31
    • 77953604719 scopus 로고    scopus 로고
    • An estimation of the annual effective dose to the Canadian population from medical CT examinations
    • Chen J and Moir D (2010) An estimation of the annual effective dose to the Canadian population from medical CT examinations. J Radiol Prot 30:131-137.
    • (2010) J Radiol Prot , Issue.30 , pp. 131-137
    • Chen, J.1    Moir, D.2
  • 36
    • 77952419547 scopus 로고    scopus 로고
    • Evaluation of lung inflammation induced by intratracheal administration of LPS in mice: Comparison between MRI and histology
    • Conti G, Tambalo S, Villetti G, Catinella S, Carnini C, Bassani F, Sonato N, Sbarbati A, and Marzola P (2010) Evaluation of lung inflammation induced by intratracheal administration of LPS in mice: Comparison between MRI and histology. MAGMA 23:93-101.
    • (2010) MAGMA , vol.23 , pp. 93-101
    • Conti, G.1    Tambalo, S.2    Villetti, G.3    Catinella, S.4    Carnini, C.5    Bassani, F.6    Sonato, N.7    Sbarbati, A.8    Marzola, P.9
  • 41
    • 65549167186 scopus 로고    scopus 로고
    • Progression of emphysema in a 12-month hyperpolarized 3He-MRI study: Lacunarity analysis provided a more sensitive measure than standard ADC analysis
    • Diaz S, Casselbrant I, Piitulainen E, Magnusson P, Peterson B, Pickering E, Tuthill T, Ekberg O, and Akeson P (2009) Progression of emphysema in a 12-month hyperpolarized 3He-MRI study: Lacunarity analysis provided a more sensitive measure than standard ADC analysis. Acad Radiol 16:700-707.
    • (2009) Acad Radiol , vol.16 , pp. 700-707
    • Diaz, S.1    Casselbrant, I.2    Piitulainen, E.3    Magnusson, P.4    Peterson, B.5    Pickering, E.6    Tuthill, T.7    Ekberg, O.8    Akeson, P.9
  • 42
    • 26944443535 scopus 로고    scopus 로고
    • Imaging drug delivery and drug responses in the lung
    • Dolovich M and Labiris R (2004) Imaging drug delivery and drug responses in the lung. Proc Am Thorac Soc 1:329-337.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 329-337
    • Dolovich, M.1    Labiris, R.2
  • 45
    • 85047682091 scopus 로고    scopus 로고
    • Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe
    • Driehuys B, Möller HE, Cleveland ZI, Pollaro J, and Hedlund LW (2009) Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe. Radiology 252:386-393.
    • (2009) Radiology , vol.252 , pp. 386-393
    • Driehuys, B.1    Möller, H.E.2    Cleveland, Z.I.3    Pollaro, J.4    Hedlund, L.W.5
  • 47
    • 0029907856 scopus 로고    scopus 로고
    • Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging
    • DOI 10.1038/nm1196-1236
    • Edelman RR, Hatabu H, Tadamura E, Li W, and Prasad PV (1996) Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging. Nature Med 2:1236-1239. (Pubitemid 26375408)
    • (1996) Nature Medicine , vol.2 , Issue.11 , pp. 1236-1239
    • Edelman, R.R.1    Hatabu, H.2    Tadamura, E.3    Li, W.4    Prasad, P.V.5
  • 51
    • 0035115602 scopus 로고    scopus 로고
    • Methodology for the measurement of mucociliary function in the mouse by scintigraphy
    • Foster WM, Walters DM, Longphre M, Macri K, and Miller LM (2001) Methodology for the measurement of mucociliary function in the mouse by scintigraphy. J Appl Physiol 90:1111-1117.
    • (2001) J Appl Physiol , vol.90 , pp. 1111-1117
    • Foster, W.M.1    Walters, D.M.2    Longphre, M.3    Macri, K.4    Miller, L.M.5
  • 53
    • 37549044235 scopus 로고    scopus 로고
    • Increased activity on In-111 octreotide imaging due to radiation fibrosis
    • Ha L, Mansberg R, Nguyen D, and Bui C (2008) Increased activity on In-111 octreotide imaging due to radiation fibrosis. Clin Nucl Med 33:46-48.
    • (2008) Clin Nucl Med , vol.33 , pp. 46-48
    • Ha, L.1    Mansberg, R.2    Nguyen, D.3    Bui, C.4
  • 54
    • 27244443240 scopus 로고    scopus 로고
    • 3He MRI in asthma: Measurements of regional ventilation following allergic sensitization and challenge in mice - Preliminary results
    • DOI 10.1016/j.acra.2005.08.027, PII S1076633205006860
    • Haczku A, Emami K, Fischer MC, Kadlecek S, Ishii M, Panettieri RA, and Rizi RR (2005) Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice-preliminary results. Acad Radiol 12:1362-1370. (Pubitemid 41512829)
    • (2005) Academic Radiology , vol.12 , Issue.11 , pp. 1362-1370
    • Haczku, A.1    Emami, K.2    Fischer, M.C.3    Kadlecek, S.4    Ishii, M.5    Panettieri, R.A.6    Rizi, R.R.7
  • 57
    • 33846194561 scopus 로고    scopus 로고
    • Visualizing lung function with positron emission tomography
    • DOI 10.1152/japplphysiol.00763.2006
    • Harris RS and Schuster DP (2007) Visualizing lung function with positron emission tomography. J Appl Physiol 102:448-458. (Pubitemid 46091596)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.1 , pp. 448-458
    • Harris, R.S.1    Schuster, D.P.2
  • 60
    • 64649097532 scopus 로고    scopus 로고
    • Noninvasive monitoring of the fate of 111In-labeled block copolymer micelles by high resolution and high sensitivity microSPECT/CT imaging
    • Hoang B, Lee H, Reilly RM, and Allen C (2009) Noninvasive monitoring of the fate of 111In-labeled block copolymer micelles by high resolution and high sensitivity microSPECT/CT imaging. Mol Pharm 6:581-592.
    • (2009) Mol Pharm , vol.6 , pp. 581-592
    • Hoang, B.1    Lee, H.2    Reilly, R.M.3    Allen, C.4
  • 61
    • 33845976636 scopus 로고    scopus 로고
    • Invasive and noninvasive lung function measurements in rodents
    • DOI 10.1016/j.vascn.2006.04.006, PII S105687190600058X
    • Hoymann HG (2007) Invasive and noninvasive lung function measurements in rodents. J Pharmacol Toxicol Methods 55:16-26. (Pubitemid 46048679)
    • (2007) Journal of Pharmacological and Toxicological Methods , vol.55 , Issue.1 , pp. 16-26
    • Hoymann, H.G.1
  • 62
    • 74049111340 scopus 로고    scopus 로고
    • Noninvasive real-time measurement of nasal mucociliary clearance in mice by pinhole gamma scintigraphy
    • Hua X, Zeman KL, Zhou B, Hua Q, Senior BA, Tilley SL, and Bennett WD (2010) Noninvasive real-time measurement of nasal mucociliary clearance in mice by pinhole gamma scintigraphy. J Appl Physiol 108:189-196.
    • (2010) J Appl Physiol , vol.108 , pp. 189-196
    • Hua, X.1    Zeman, K.L.2    Zhou, B.3    Hua, Q.4    Senior, B.A.5    Tilley, S.L.6    Bennett, W.D.7
  • 63
    • 77951519902 scopus 로고    scopus 로고
    • Vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis
    • Jacob RE, Amidan BG, Soelberg J, and Minard KR (2010) In vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis. J Magn Reson Imaging 31:1091-1099.
    • (2010) J Magn Reson Imaging , vol.31 , pp. 1091-1099
    • Jacob, R.E.1    Amidan, B.G.2    Soelberg, J.3    Minard, K.R.4
  • 66
    • 34247279786 scopus 로고    scopus 로고
    • Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging
    • DOI 10.1038/sj.bjp.0707168, PII 0707168
    • Karmouty-Quintana H, Cannet C, Sugar R, Fozard JR, Page CP, and Beckmann N (2007a) Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging. Br J Pharmacol 150:1022-1030. (Pubitemid 46625088)
    • (2007) British Journal of Pharmacology , vol.150 , Issue.8 , pp. 1022-1030
    • Karmouty-Quintana, H.1    Cannet, C.2    Sugar, R.3    Fozard, J.R.4    Page, C.P.5    Beckmann, N.6
  • 68
    • 70349170220 scopus 로고    scopus 로고
    • MR diagnosis of a pulmonary embolism: Comparison of P792 and Gd-DOTA for first-pass perfusion MRI and contrast-enhanced 3D MRA in a rabbit model
    • Keilholz SD, Bozlar U, Fujiwara N, Mata JF, Berr SS, Corot C, and Hagspiel KD (2009) MR diagnosis of a pulmonary embolism: Comparison of P792 and Gd-DOTA for first-pass perfusion MRI and contrast-enhanced 3D MRA in a rabbit model. Korean J Radiol 10:447-454.
    • (2009) Korean J Radiol , vol.10 , pp. 447-454
    • Keilholz, S.D.1    Bozlar, U.2    Fujiwara, N.3    Mata, J.F.4    Berr, S.S.5    Corot, C.6    Hagspiel, K.D.7
  • 70
    • 35648947301 scopus 로고    scopus 로고
    • Micro-CT imaging of rat lung ventilation using continuous image acquisition during xenon gas contrast enhancement
    • DOI 10.1152/japplphysiol.00009.2007
    • Lam WW, Holdsworth DW, Du LY, Drangova M, McCormack DG, and Santyr GE (2007) Micro-CT imaging of rat lung ventilation using continuous image acquisition during xenon gas contrast enhancement. J Appl Physiol 103:1848-1856. (Pubitemid 350033873)
    • (2007) Journal of Applied Physiology , vol.103 , Issue.5 , pp. 1848-1856
    • Lam, W.W.1    Holdsworth, D.W.2    Du, L.Y.3    Drangova, M.4    McCormack, D.G.5    Santyr, G.E.6
  • 73
    • 78651462589 scopus 로고    scopus 로고
    • Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects
    • Lenney W, Edenborough F, Kho P, and Kovarik JM (2011) Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects. J Cyst Fibros 10:9-14.
    • (2011) J Cyst Fibros , vol.10 , pp. 9-14
    • Lenney, W.1    Edenborough, F.2    Kho, P.3    Kovarik, J.M.4
  • 74
    • 34250155965 scopus 로고    scopus 로고
    • Assessment of the relationship between lung parenchymal destruction and impaired pulmonary perfusion on a lobar level in patients with emphysema
    • DOI 10.1016/j.ejrad.2007.01.020, PII S0720048X07000344, Hip Joint
    • Ley-Zaporozhan J, Ley S, Eberhardt R, Weinheimer O, Fink C, Puderbach M, Eichinger M, Herth F, and Kauczor HU (2007) Assessment of the relationship between lung parenchymal destruction and impaired pulmonary perfusion on a lobar level in patients with emphysema. Eur J Radiol 63:76-83. (Pubitemid 46907473)
    • (2007) European Journal of Radiology , vol.63 , Issue.1 , pp. 76-83
    • Ley-Zaporozhan, J.1    Ley, S.2    Eberhardt, R.3    Weinheimer, O.4    Fink, C.5    Puderbach, M.6    Eichinger, M.7    Herth, F.8    Kauczor, H.-U.9
  • 75
    • 39049140717 scopus 로고    scopus 로고
    • Morphological and functional imaging in COPD with CT and MRI: Present and future
    • DOI 10.1007/s00330-007-0772-1
    • Ley-Zaporozhan J, Ley S, and Kauczor HU (2008a) Morphological and functional imaging in COPD with CT and MRI: Present and future. Eur Radiol 18:510-521. (Pubitemid 351248182)
    • (2008) European Radiology , vol.18 , Issue.3 , pp. 510-521
    • Ley-Zaporozhan, J.1    Ley, S.2    Kauczor, H.-U.3
  • 80
    • 27244452469 scopus 로고    scopus 로고
    • Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: Assessment at baseline and after bronchodilator and airway clearance treatment
    • DOI 10.1016/j.acra.2005.07.008, PII S1076633205006471
    • Mentore K, Froh DK, de Lange EE, Brookeman JR, Paget-Brown AO, and Altes TA (2005) Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: Assessment at baseline and after bronchodilator and airway clearance treatment. Acad Radiol 12:1423-1429. (Pubitemid 41512835)
    • (2005) Academic Radiology , vol.12 , Issue.11 , pp. 1423-1429
    • Mentore, K.1    Froh, D.K.2    De Lange, E.E.3    Brookeman, J.R.4    Paget-Brown, A.O.5    Altes, T.A.6
  • 81
    • 61849179561 scopus 로고    scopus 로고
    • Vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure
    • Merkel OM, Librizzi D, Pfestroff A, Schurrat T, Béhé M, and Kissel T (2009) In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure. Bioconjug Chem 20:174-182.
    • (2009) Bioconjug Chem , vol.20 , pp. 174-182
    • Merkel, O.M.1    Librizzi, D.2    Pfestroff, A.3    Schurrat, T.4    Béhé, M.5    Kissel, T.6
  • 82
    • 38949202992 scopus 로고    scopus 로고
    • Pulmonary perfusion imaging in the rodent lung using dynamic contrast-enhanced MRI
    • DOI 10.1002/mrm.21353
    • Mistry NN, Pollaro J, Song J, De Lin M, and Johnson GA (2008) Pulmonary perfusion imaging in the rodent lung using dynamic contrast-enhanced MRI. Magn Reson Med 59:289-297. (Pubitemid 351220092)
    • (2008) Magnetic Resonance in Medicine , vol.59 , Issue.2 , pp. 289-297
    • Mistry, N.N.1    Pollaro, J.2    Song, J.3    Ming, D.L.4    Johnson, G.A.5
  • 83
    • 77649090016 scopus 로고    scopus 로고
    • Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine
    • Mistry NN, Thomas A, Kaushik SS, Johnson GA, and Driehuys B (2010) Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine. Magn Reson Med 63:658-666.
    • (2010) Magn Reson Med , vol.63 , pp. 658-666
    • Mistry, N.N.1    Thomas, A.2    Kaushik, S.S.3    Johnson, G.A.4    Driehuys, B.5
  • 84
    • 77952690903 scopus 로고    scopus 로고
    • Spatially resolved assessment of serotonin-induced bronchoconstrictive responses in the rat lung using 3He ventilation MRI under spontaneous breathing conditions
    • Mosbah K, Stupar V, Berthezène Y, Beckmann N, and Crémillieux Y (2010) Spatially resolved assessment of serotonin-induced bronchoconstrictive responses in the rat lung using 3He ventilation MRI under spontaneous breathing conditions. Magn Reson Med 63:1669-1674.
    • (2010) Magn Reson Med , vol.63 , pp. 1669-1674
    • Mosbah, K.1    Stupar, V.2    Berthezène, Y.3    Beckmann, N.4    Crémillieux, Y.5
  • 86
    • 67749145553 scopus 로고    scopus 로고
    • Quantification of pulmonary blood flow (PBF): Validation of perfusion MRI and nonlinear contrast agent (CA) dose correction with H(2)15O positron emission tomography (PET)
    • Neeb D, Kunz RP, Ley S, Szábo G, Strauss LG, Kauczor HU, Kreitner KF, and Schreiber LM (2009) Quantification of pulmonary blood flow (PBF): Validation of perfusion MRI and nonlinear contrast agent (CA) dose correction with H(2)15O positron emission tomography (PET). Magn Reson Med 62:476-487.
    • (2009) Magn Reson Med , vol.62 , pp. 476-487
    • Neeb, D.1    Kunz, R.P.2    Ley, S.3    Szábo, G.4    Strauss, L.G.5    Kauczor, H.U.6    Kreitner, K.F.7    Schreiber, L.M.8
  • 87
    • 70350465303 scopus 로고    scopus 로고
    • Utility of phase contrast MR imaging for assessment of pulmonary flow and pressure estimation in patients with pulmonary hypertension: Comparison with right heart catheterization and echocardiography
    • Nogami M, Ohno Y, Koyama H, Kono A, Takenaka D, Kataoka T, Kawai H, Kawamitsu H, Onishi Y, Matsumoto K, et al. (2009) Utility of phase contrast MR imaging for assessment of pulmonary flow and pressure estimation in patients with pulmonary hypertension: Comparison with right heart catheterization and echocardiography. J Magn Reson Imaging 30:973-980.
    • (2009) J Magn Reson Imaging , vol.30 , pp. 973-980
    • Nogami, M.1    Ohno, Y.2    Koyama, H.3    Kono, A.4    Takenaka, D.5    Kataoka, T.6    Kawai, H.7    Kawamitsu, H.8    Onishi, Y.9    Matsumoto, K.10
  • 88
    • 69249231134 scopus 로고    scopus 로고
    • Optical imaging of molecular signatures in pulmonary inflammation
    • Ntziachristos V (2009) Optical imaging of molecular signatures in pulmonary inflammation. Proc Am Thorac Soc 6:416-418.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 416-418
    • Ntziachristos, V.1
  • 89
    • 43849097396 scopus 로고    scopus 로고
    • Oxygen-enhanced magnetic resonance imaging versus computed tomography: Multicenter study for clinical stage classification of smoking-related chronic obstructive pulmonary disease
    • DOI 10.1164/rccm.200709-1322OC
    • Ohno Y, Iwasawa T, Seo JB, Koyama H, Takahashi H, Oh YM, Nishimura Y, and Sugimura K (2008) Oxygen-enhanced magnetic resonance imaging versus computed tomography: Multicenter study for clinical stage classification of smokingrelated chronic obstructive pulmonary disease. Am J Respir Crit Care Med 177: 1095-1102. (Pubitemid 351717568)
    • (2008) American Journal of Respiratory and Critical Care Medicine , vol.177 , Issue.10 , pp. 1095-1102
    • Ohno, Y.1    Iwasawa, T.2    Joom, B.S.3    Koyama, H.4    Takahashi, H.5    Oh, Y.-M.6    Nishimura, Y.7    Sugimura, K.8
  • 90
    • 79953786854 scopus 로고    scopus 로고
    • Oxygen-enhanced MRI vs. quantitatively assessed thinsection CT: Pulmonary functional loss assessment and clinical stage classification of asthmatics
    • Ohno Y, Koyama H, Matsumoto K, Onishi Y, Nogami M, Takenaka D, Matsumoto S, and Sugimura K (2011) Oxygen-enhanced MRI vs. quantitatively assessed thinsection CT: Pulmonary functional loss assessment and clinical stage classification of asthmatics. Eur J Radiol 77:85-91.
    • (2011) Eur J Radiol , vol.77 , pp. 85-91
    • Ohno, Y.1    Koyama, H.2    Matsumoto, K.3    Onishi, Y.4    Nogami, M.5    Takenaka, D.6    Matsumoto, S.7    Sugimura, K.8
  • 94
    • 33846220208 scopus 로고    scopus 로고
    • Physiological imaging of the lung: Single-photon-emission computed tomography (SPECT)
    • DOI 10.1152/japplphysiol.00732.2006
    • Petersson J, Sánchez-Crespo A, Larsson SA, and Mure M (2007) Physiological imaging of the lung: Single-photon-emission computed tomography (SPECT). J Appl Physiol 102:468-476. (Pubitemid 46091597)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.1 , pp. 468-476
    • Petersson, J.1    Sanchez-Crespo, A.2    Larsson, S.A.3    Mure, M.4
  • 100
    • 67649186010 scopus 로고    scopus 로고
    • Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure
    • Reiter G, Reiter U, Kovacs G, Kainz B, Schmidt K, Maier R, Olschewski H, and Rienmueller R (2008) Magnetic resonance-derived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure. Circ Cardiovasc Imaging 1:23-30.
    • (2008) Circ Cardiovasc Imaging , vol.1 , pp. 23-30
    • Reiter, G.1    Reiter, U.2    Kovacs, G.3    Kainz, B.4    Schmidt, K.5    Maier, R.6    Olschewski, H.7    Rienmueller, R.8
  • 103
    • 67649422713 scopus 로고    scopus 로고
    • Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: An experimental study
    • Richard JC, Pouzot C, Gros A, Tourevieille C, Lebars D, Lavenne F, Frerichs I, and Guérin C (2009) Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: An experimental study. Crit Care 13:R82.
    • (2009) Crit Care , vol.13
    • Richard, J.C.1    Pouzot, C.2    Gros, A.3    Tourevieille, C.4    Lebars, D.5    Lavenne, F.6    Frerichs, I.7    Guérin, C.8
  • 105
    • 23644462253 scopus 로고    scopus 로고
    • The spatial and temporal heterogeneity of regional ventilation: Comparison of measurements by two high-resolution methods
    • DOI 10.1016/j.resp.2005.05.008, PII S1569904805001394
    • Robertson HT, Kreck TC, and Krueger MA (2005) The spatial and temporal heterogeneity of regional ventilation: Comparison of measurements by two highresolution methods. Respir Physiol Neurobiol 148:85-95. (Pubitemid 41132751)
    • (2005) Respiratory Physiology and Neurobiology , vol.148 , Issue.SPEC. ISS. , pp. 85-95
    • Robertson, H.T.1    Kreck, T.C.2    Krueger, M.A.3
  • 106
    • 34547918822 scopus 로고    scopus 로고
    • Regional pulmonary perfusion using model-free analysis of contrast-enhanced mri in meconium-aspirated piglets
    • DOI 10.1002/jmri.20975
    • Ryhammer P, Pedersen M, Ringgaard S, and Ravn H (2007) Regional pulmonary perfusion using model-free analysis of contrast-enhanced MRI in meconiumaspirated piglets. J Magn Reson Imaging 26:296-303. (Pubitemid 47257727)
    • (2007) Journal of Magnetic Resonance Imaging , vol.26 , Issue.2 , pp. 296-303
    • Ryhammer, P.1    Pedersen, M.2    Ringgaard, S.3    Ravn, H.4
  • 107
    • 67649200182 scopus 로고    scopus 로고
    • Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo biodistribution evaluation using MicroSPECT/ CT imaging
    • Saatchi K and Häfeli UO (2009) Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo biodistribution evaluation using MicroSPECT/ CT imaging. Bioconjug Chem 20:1209-1217.
    • (2009) Bioconjug Chem , vol.20 , pp. 1209-1217
    • Saatchi, K.1    Häfeli, U.O.2
  • 111
    • 34250159800 scopus 로고    scopus 로고
    • A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice
    • DOI 10.1080/01902140701364458, PII 779292672
    • Shofer S, Badea C, Auerbach S, Schwartz DA, and Johnson GA (2007) A microcomputed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice. Exp Lung Res 33:169-183. (Pubitemid 46897655)
    • (2007) Experimental Lung Research , vol.33 , Issue.3-4 , pp. 169-183
    • Shofer, S.1    Badea, C.2    Auerbach, S.3    Schwartz, D.A.4    Johnson, G.A.5
  • 114
    • 70449132318 scopus 로고    scopus 로고
    • Progression of emphysema evaluated by MRI using hyperpolarized (3)He (HP (3)He) measurements in patients with α-1-antitrypsin (A1AT) deficiency compared with CT and lung function tests
    • Stavngaard T, Søgaard LV, Batz M, Schreiber LM, and Dirksen A (2009) Progression of emphysema evaluated by MRI using hyperpolarized (3)He (HP (3)He) measurements in patients with α-1-antitrypsin (A1AT) deficiency compared with CT and lung function tests. Acta Radiol 50:1019-1026.
    • (2009) Acta Radiol , vol.50 , pp. 1019-1026
    • Stavngaard, T.1    Søgaard, L.V.2    Batz, M.3    Schreiber, L.M.4    Dirksen, A.5
  • 115
    • 7044220579 scopus 로고    scopus 로고
    • Optimization and standardization of lung densitometry in the assessment of pulmonary emphysema
    • DOI 10.1097/00004424-200411000-00006
    • Stoel BC and Stolk J (2004) Optimization and standardization of lung densitometry in the assessment of pulmonary emphysema. Invest Radiol 39:681-688. (Pubitemid 39425961)
    • (2004) Investigative Radiology , vol.39 , Issue.11 , pp. 681-688
    • Stoel, B.C.1    Stolk, J.2
  • 116
    • 33947522225 scopus 로고    scopus 로고
    • 3He ventilation imaging under spontaneous breathing conditions: A non-invasive protocol for small-animal lung function imaging
    • DOI 10.1002/nbm.1086
    • Stupar V, Canet-Soulas E, Gaillard S, Alsaid H, Beckmann N, and Crémillieux Y (2007) Retrospective cine 3He ventilation imaging under spontaneous breathing conditions: A noninvasive protocol for small-animal lung function imaging. NMR Biomed 20:104-112. (Pubitemid 46470932)
    • (2007) NMR in Biomedicine , vol.20 , Issue.2 , pp. 104-112
    • Stupar, V.1    Canet-Soulas, E.2    Gaillard, S.3    Alsaid, H.4    Beckmann, N.5    Cremillieux, Y.6
  • 117
    • 77952367198 scopus 로고    scopus 로고
    • Multidetector high-resolution computed tomography of the lungs: Protocols and applications
    • Sundaram B, Chughtai AR, and Kazerooni EA (2010) Multidetector high-resolution computed tomography of the lungs: Protocols and applications. J Thorac Imaging 25:125-141.
    • (2010) J Thorac Imaging , vol.25 , pp. 125-141
    • Sundaram, B.1    Chughtai, A.R.2    Kazerooni, E.A.3
  • 123
    • 0345599925 scopus 로고    scopus 로고
    • Effects of a mitogen-activated protein kinase inhibitor on allergic airways inflammation in the rat studied by magnetic resonance imaging
    • DOI 10.1016/j.ejphar.2003.09.052
    • Tigani B, Di Padova F, Zurbrügg S, Schaeublin E, Revesz L, Fozard JR, and Beckmann N (2003b) Effects of a mitogen-activated protein kinase inhibitor on allergic airways inflammation in the rat studied by magnetic resonance imaging. Eur J Pharmacol 482:319-324. (Pubitemid 37505959)
    • (2003) European Journal of Pharmacology , vol.482 , Issue.1-3 , pp. 319-324
    • Tigani, B.1    Di Padova, F.2    Zurbrugg, S.3    Schaeublin, E.4    Revesz, L.5    Fozard, J.R.6    Beckmann, N.7
  • 126
    • 29144514433 scopus 로고    scopus 로고
    • Intrathoracic airway trees: Segmentation and airway morphology analysis from low-dose CT scans
    • DOI 10.1109/TMI.2005.857654
    • Tschirren J, Hoffman EA, McLennan G, and Sonka M (2005) Intrathoracic airway trees: Segmentation and airway morphology analysis from low-dose CT scans. IEEE Trans Med Imaging 24:1529-1539. (Pubitemid 41812021)
    • (2005) IEEE Transactions on Medical Imaging , vol.24 , Issue.12 , pp. 1529-1539
    • Tschirren, J.1    Huffman, E.A.2    McLennan, G.3    Sonka, M.4
  • 127
    • 18544408061 scopus 로고    scopus 로고
    • Octreotide inhibits hepatic fibrosis, bile duct proliferation and bacterial translocation in obstructive jaundice
    • Türkçapar N, Bayar S, Koyuncu A, and Ceyhan K (2003) Octreotide inhibits hepatic fibrosis, bile duct proliferation and bacterial translocation in obstructive jaundice. Hepatogastroenterology 50:680-683. (Pubitemid 36613379)
    • (2003) Hepato-Gastroenterology , vol.50 , Issue.51 , pp. 680-683
    • Turkcapar, N.1    Bayar, S.2    Koyuncu, A.3    Ceyhan, K.4
  • 128
    • 64349104057 scopus 로고    scopus 로고
    • The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI
    • Tzeng YS, Lutchen K, and Albert M (2009) The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI. J Appl Physiol 106:813-822.
    • (2009) J Appl Physiol , vol.106 , pp. 813-822
    • Tzeng, Y.S.1    Lutchen, K.2    Albert, M.3
  • 130
    • 77956713444 scopus 로고    scopus 로고
    • Validation of high-resolution echocardiography and magnetic resonance imaging vs. highfidelity catheterization in experimental pulmonary hypertension
    • Urboniene D, Haber I, Fang YH, Thenappan T, and Archer SL (2010) Validation of high-resolution echocardiography and magnetic resonance imaging vs. highfidelity catheterization in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 299:L401-L412.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299
    • Urboniene, D.1    Haber, I.2    Fang, Y.H.3    Thenappan, T.4    Archer, S.L.5
  • 131
    • 34247518666 scopus 로고    scopus 로고
    • Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: Comparison with Shwachman score, Chrispin-Norman score and spirometry
    • DOI 10.1007/s00330-006-0392-1
    • van Beek EJ, Hill C, Woodhouse N, Fichele S, Fleming S, Howe B, Bott S, Wild JM, and Taylor CJ (2007) Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-helium MRI: Comparison with Shwachman score, Chrispin- Norman score and spirometry. Eur Radiol 17:1018-1024. (Pubitemid 46766883)
    • (2007) European Radiology , vol.17 , Issue.4 , pp. 1018-1024
    • Van Beek, E.J.R.1    Hill, C.2    Woodhouse, N.3    Fichele, S.4    Fleming, S.5    Howe, B.6    Bott, S.7    Wild, J.M.8    Taylor, C.J.9
  • 133
    • 0036725257 scopus 로고    scopus 로고
    • Changes in regional ventilation after autologous blood clot pulmonary embolism
    • DOI 10.1097/00000542-200209000-00022
    • Vidal Melo MF, Harris RS, Layfield D, Musch G, and Venegas JG (2002) Changes in regional ventilation after autologous blood clot pulmonary embolism. Anesthesiology 97:671-681. (Pubitemid 34977328)
    • (2002) Anesthesiology , vol.97 , Issue.3 , pp. 671-681
    • Vidal Melo, M.F.1    Harris, R.S.2    Layfield, D.3    Musch, G.4    Venegas, J.G.5
  • 135
    • 75149152375 scopus 로고    scopus 로고
    • Spatial heterogeneity of lung perfusion assessed with (13)N PET as a vascular biomarker in chronic obstructive pulmonary disease
    • Vidal Melo MF, Winkler T, Harris RS, Musch G, Greene RE, and Venegas JG (2010) Spatial heterogeneity of lung perfusion assessed with (13)N PET as a vascular biomarker in chronic obstructive pulmonary disease. J Nucl Med 51:57-65.
    • (2010) J Nucl Med , vol.51 , pp. 57-65
    • Vidal Melo, M.F.1    Winkler, T.2    Harris, R.S.3    Musch, G.4    Greene, R.E.5    Venegas, J.G.6
  • 136
    • 25844519071 scopus 로고    scopus 로고
    • Time and tidal volumedependent ventilator-induced lung injury in healthy rats
    • Walder B, Fontao E, Totsch M, and Morel DR (2005) Time and tidal volumedependent ventilator-induced lung injury in healthy rats. Eur J Anaesthesiol 22:785-794.
    • (2005) Eur J Anaesthesiol , vol.22 , pp. 785-794
    • Walder, B.1    Fontao, E.2    Totsch, M.3    Morel, D.R.4
  • 137
    • 77950956188 scopus 로고    scopus 로고
    • Measurement of regional specific lung volume change using respiratorygated PET of inhaled 13N-nitrogen
    • Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, and Melo MF (2010) Measurement of regional specific lung volume change using respiratorygated PET of inhaled 13N-nitrogen. J Nucl Med 51:646-653.
    • (2010) J Nucl Med , vol.51 , pp. 646-653
    • Wellman, T.J.1    Winkler, T.2    Costa, E.L.3    Musch, G.4    Harris, R.S.5    Venegas, J.G.6    Melo, M.F.7
  • 138
    • 70350445915 scopus 로고    scopus 로고
    • Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: A pilot study in pediatric cystic fibrosis
    • Woodhouse N, Wild JM, van Beek EJ, Hoggard N, Barker N, and Taylor CJ (2009) Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: A pilot study in pediatric cystic fibrosis. J Magn Reson Imaging 30:981-988.
    • (2009) J Magn Reson Imaging , vol.30 , pp. 981-988
    • Woodhouse, N.1    Wild, J.M.2    Van Beek, E.J.3    Hoggard, N.4    Barker, N.5    Taylor, C.J.6
  • 140
    • 22244483918 scopus 로고    scopus 로고
    • 11C-zolmitriptan assessed by positron emission tomography
    • DOI 10.1111/j.1468-2982.2005.00966.x
    • Yates R, Sörensen J, Bergström M, Antoni G, Nairn K, Kemp J, Långström B, and Dane A (2005) Distribution of intranasal C-zolmitriptan assessed by positron emission tomography. Cephalalgia 25:1103-1109. (Pubitemid 41774856)
    • (2005) Cephalalgia , vol.25 , Issue.12 , pp. 1103-1109
    • Yates, R.1    Sorensen, J.2    Bergstrom, M.3    Antoni, G.4    Nairn, K.5    Kemp, J.6    Langstrom, B.7    Dane, A.8
  • 141
    • 35848938695 scopus 로고    scopus 로고
    • Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging
    • DOI 10.1016/j.bmcl.2007.10.013, PII S0960894X07011833
    • Zhang Y, Kundu B, Fairchild KD, Locke L, Berr SS, Linden J, and Pan D (2007) Synthesis of novel neutrophil-specific imaging agents for positron emission tomography (PET) imaging. Bioorg Med Chem Lett 17:6876-6878. (Pubitemid 350061297)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.24 , pp. 6876-6878
    • Zhang, Y.1    Kundu, B.2    Fairchild, K.D.3    Locke, L.4    Berr, S.S.5    Linden, J.6    Pan, D.7
  • 142
    • 77955116866 scopus 로고    scopus 로고
    • Validation of simple and robust protocols for high-resolution lung proton MRI in mice
    • Zurek M, Bessaad A, Cieslar K, and Crémillieux Y (2010) Validation of simple and robust protocols for high-resolution lung proton MRI in mice. Magn Reson Med 64:401-407.
    • (2010) Magn Reson Med , vol.64 , pp. 401-407
    • Zurek, M.1    Bessaad, A.2    Cieslar, K.3    Crémillieux, Y.4


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