Ganoderma applanatum terpenes protect mouse liver against benzo(α)pyren-induced oxidative stress and inflammation

Environmental Toxicology and Pharmacology

Volumn 31, Issue 3, 2011, Pages 460-468

  Ma, Jie Qiong ^a,b   Liu, Chan Min ^b   Qin, Zhi Hong ^a   Jiang, Ji Hong ^b   Sun, Yun Zhi ^b  

^a CHINA UNIVERSITY OF MINING AND TECHNOLOGY   (China)

^b JIANGSU NORMAL UNIVERSITY   (China)

Author keywords

Benzo(a)pyrene; Ganoderma applanatum terpenes; Inflammatory response; Mouse liver; Oxidative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; BENZO[A]PYRENE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOOXYGENASE 2; GANODERMA APPLANATUM EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MALONALDEHYDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TERPENE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GANODERMA; GANODERMA APPLANATUM; HEPATITIS; HISTOPATHOLOGY; LIVER INJURY; LIVER PARENCHYMA; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BENZO(A)PYRENE; BLOTTING, WESTERN; CATALASE; CYCLOOXYGENASE 2; DRUG-INDUCED LIVER INJURY; ENVIRONMENTAL POLLUTANTS; GANODERMA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INFLAMMATION; INTERLEUKIN-1BETA; LIPID PEROXIDATION; LIVER; LIVER FUNCTION TESTS; MALE; MICE; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TERPENES;

GANODERMA APPLANATUM; MUS;

EID: 79954856353     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2011.02.007     Document Type: Article

References (52)

1. Aebi H. Catalase in vitro. Methods Enzymol. 1984, 105:121-126.
2. Acharya K., Yonzone P., Rai M., Rupa A. Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum. Indian J. Exp. Biol. 2005, 43:629-926.
3. Burke M.D., Vadi H., Jernstorm B., Orrenius S. Metabolism of benzo(a)pyrene derivaties by UDP-glucronyl-transferase of nuclear envelope. Biochem. Biophys. Res. Commun. 1981, 98:131-139.
4. Collino M., Aragno M., Castiglia S., Tomasinelli C., Thiemermann C., Boccuzzi G., Fantozzi R. Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta. Diabetes 2009, 58:235-242.
5. Dambach D.M., Durham S.K., Laskinc J.D., Laskin D.L. Distinct roles of NF-κB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol. Appl. Pharmacol. 2006, 211:157-165.
6. Dudhgaonkar S., Thyagarajan A., Sliva D. Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum. Int. Immunopharmacol. 2009, 9:1272-1280.
7. Gangar S.C., Sandhir R., Rai D.V., Koul A. Preventive effects of Azadirachta indica on benzo(a)pyrene-DNA adduct formation in murine forestomach and hepatic tissues. Phytother. Res. 2006, 20:889-895.
8. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferase the first step in mercapturic acid formation. J. Biol. Chem. 1974, 249:7130-7139.
9. Hartman P.E., Shankel D.W. Antimutagens and anticarcinogens: a survey of putative interceptor molecules. Environ. Mol. Mutagen. 1990, 15:145-182.
10. Hattemer-Frey H.A., Travis C.C. Benzo-a-pyrene: environmental partitioning and human exposure. Toxicol. Ind. Health 1991, 7:141-157.
11. Hiramatsu N., Kasai A., Hayakawa K., Nagai K., Kubota T., Yao J., Kitamura M. Secreted protein-based reporter systems for monitoring inflammatory events: critical interference by endoplasmic reticulum stress. J. Immunol. Methods 2006, 315:202-207.
12. Hideshima T., Ikeda H., Chauhan D., Okawa Y., Raje N., Podar K., Mitsiades C., Munshi N.C., Richardson P.G., Carrasco R.D., Anderson K.C. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells. Blood 2009, 114:1046-1052.
13. Hwang Y.S., Jeong M., Park J.S., Kim M.H., Lee D.B., Shin B.A., Mukaida N., Ellis L.M., Kim H.R., Ahn B.W., Jung Y.D. Interleukin-1β stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. Oncogene 2004, 23:6603-6611.
14. Jahangir T., Sultana S. Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. J. Enzyme Inhib. Med. Chem. 2008, 23:888-894.
15. Janabi N. Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Δ(12,14)(12,14)-prostaglandin J(2) inactivated human astrocytes, but not in human brain macrophages. J. Immunol. 2002, 168:4747-4755.
16. Jeong Y.T., Yang B.K., Jeong S.C., Kim S.M., Song C.H. Ganoderma applanatum: a promising mushroom for antitumor and immunomodulating activity. Phytother. Res. 2008, 22:614-619.
17. Khalil A., Villard P.H., Dao M.A., Burceli R., Champion S., Fouchier F., Savouret J.F., Barra Y., Seree E. Polycyclic aromatic hydrocarbon spotentiate high-fat diet effects on intestinal inflammation. Toxicol. Lett. 2010, 196:161-167.
18. Khan T.H., Jahangir T., Prasad L., Sultana S. Inhibitory effect of apigenin on benzo(a)pyrene-mediated genotoxicity in Swiss albino mice. J. Pharm. Pharmacol. 2006, 58:1655-1660.
19. Kim H.J., Yu M.H., Lee I.S. Inhibitory effects of methanol extract of plum (Prunus salicina L., cv. 'Soldam') fruits against benzo(a)pyrene-induced toxicity in mice. Food Chem. Toxicol. 2008, 46:3407-3413.
20. Kim K.B., Lee B.M. Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene. Cancer Lett. 1997, 113:205-212.
21. Lakshmi B., Ajith T.A., Nayana J., Janardhanan K.K. Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effecton hepatic damage caused by benzo[a]pyrene. J. Ethnopharmacol. 2006, 107:297-303.
22. Laskin D.L., Laskin J.D. Role of macrophages and inflammatory mediators in chemically induced toxicity. Toxicology 2001, 160:111-118.
23. Lecureur V., Ferrec E.L., N'diaye M., Vee M.L., Gardyn C., Gilot D., Fardel O. ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Lett. 2005, 579:1904-1910.
24. Lee S.H., Shim S.H., Kim J.S., Kang S.S. Constituents from the fruiting bodies of Ganoderma applanatum and their aldose reductase inhibitory activity. Arch. Pharm. Res. 2006, 29:479-483.
25. Li Y., Qi J., Liu K., Li B., Wang H., Jia J. Peroxynitrite-induced nitration of cyclooxygenase-2 and inducible nitric oxide synthase promotes their binding in diabetic angiopathy. Mol. Med. 2010, 16:335-342.
26. Liu C.M., Ma J.Q., Lou Y. Chronic administration of troxerutin protects mouse kidney against d-galactose-induced oxidative DNA damage. Food Chem. Toxicol. 2010, 48:2809-2817.
27. Liu C.M., Ma J.Q., Sun Y.Z. Quercetin protects the rat kidney against oxidative stress-mediated DNA damage and apoptosis induced by lead. Environ. Toxicol. Pharmacol. 2010, 30:264-271.
28. Mak D.H., Ip S.P., Lip C., Poon M.K., Ko K.M. Effects of schisandrin B and alpha-tocopherol on lipid peroxidation, in vitro and in vivo. Mol. Cell Biochem. 1996, 165:161-165.
29. Marie-Desvergne C., Maître A., Bouchard M., Ravanat J.L., Viau C. Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-Hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats. Chem. Res. Toxicol. 2010, 23:1207-1214.
30. McCord J.M., Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 1969, 244:6049-6055.
31. Molina-Holgado E., Ortiz S., Molina-Holgado F., Guaza C. Induction of COX-2 and PGE2 biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes. Br. J. Pharmacol. 2000, 131:152-159.
32. Müller-Decker K., Berger I., Ackermann K., Ehemann V., Zoubova S., Aulmann S., Pyerin W., Frstenberger G. Cystic duct dilatations and proliferative epithelial lesions in mouse mammary glands upon keratin 5 promoter-driven overexpression of cyclooxygenase-2. Am. J. Pathol. 2005, 166:575-584.
33. Paglia D.E., Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 1967, 70:158-169.
34. Pang L., Ye W., Che X.M., Roessler B.J., Betz A.L., Yang G.Y. Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor-β1 expression. Stroke 2001, 32:544-552.
35. Park S.Y., Phark S., Lee M., Lim J.Y., Su D. Anti-oxidative and anti-inflammatory activities of placental extracts in benzo[a]pyrene-exposed rats. Placenta 2010, 31:873-879.
36. Paterson R.R.M. Ganoderma-a therapeutic fungal biofactory. Phytochemistry 2006, 67:1985-2001.
37. Pillai T.G., John M., Thomas G.S. Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern parts of India. Exp. Toxicol. Pathol. 2011, 63:157-160.
38. Qu X.J., Xia X., Wang Y.S., Song M.J., Liu L.L., Xie Y.Y., Cheng Y.N., Liu X.J., Qiu L.L., Xiang L., Gao J.J., Zhang X.F., Cui S.X. Protective effects of Salvia plebeia compound homoplantaginin on hepatocyte injury. Food Chem. Toxicol. 2009, 47:1710-1715.
39. Reitman S., Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 1957, 28:56-63.
40. Sagredo C., Øvrebø S., Haugen A., Fujii-Kuriyama Y., Baera R., Botnen I.V., Mollerup S. Quantitative analysis of benzo[a]pyrene biotransformation and adduct formation in Ahr knockout mice. Toxicol. Lett. 2006, 167:173-182.
41. Seto S.W., Lam T.Y., Tam H.L., Au A.L., Chan S.W., Wu J.H., Yu P.H., Leung G.P., Ngai S.M., Yeung J.H., Leung P.S., Lee S.M., Kwan Y.W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice. Phytomedicine 2009, 16:426-436.
42. Sharma R., Haque A.K., Awasthi S., Singh S.V., Piper J.T., Awasthi Y.C. Differential carcinogenicity of benzo[a]pyrene in male and female CD-1 mouse lung. J. Toxicol. Environ. Health 1997, 52:45-62.
43. Shinomol G., Muralidhara K. Differential induction of oxidative impairments in brain regions of male mice following subchronic consumption of Khesari dhal (Lathyrus sativus) and detoxified Khesari dhal. Neurotoxicology 2007, 28:798-806.
44. Singh S.V., Hu X., Srivastava S.K., Singh M., Xia H., Orchard J.L., Zaren H.A. Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin. Carcinogenesis 1998, 19:1357-1360.
45. Takaishi M., Sawada M., Shimada A., Suzuki J.S., Satoh M., Nagase H. Protective role of metallothionein in benzo[a]pyrene-induced DNA damage. J. Toxicol. Sci. 2009, 34:449-458.
46. Uchiyama M., Mihara M. Determination of malondialdehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 1978, 86:271-278.
47. Umannová L., Machala M., Topinka J., Nováková Z., Milcová A., Kozubík A., Vondrácek J. Tumor necrosis factor-alpha potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression. Mutat. Res. 2008, 640:162-169.
48. Uwe S. Anti-inflammatory interventions of NF-κB signaling: potential applications and risks. Biochem. Pharmacol. 2008, 75:1567-1579.
49. Weng M.W., Hsiao Y.M., Chen C.J., Wang J.P., Chen W.C., Ko J.L. Benzo[a]pyrene diol epoxide up-regulates COX-2 expression through NF-κB in rat astrocytes. Toxicol. Lett. 2004, 151:345-355.
50. Yang B.K., Jung Y.S., Song C.H. Hypoglycemic effects of Ganoderma applanatum and Collybia confluens exo-polymers in streptozotocin-induced diabetic rats. Phytother. Res. 2007, 21:1066-1069.
51. Zhang G.L., Wang Y.H., Ni W., Teng H.L., Lin Z.B. Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice. World J. Gastroenterol. 2002, 8:728-733.
52. Zhou X., Lin J., Yin Y., Zhao J., Sun X., Tang K. Ganodermataceae: natural products and their related pharmacological functions. Am. J. Chin. Med. 2007, 35:559-574.