메뉴 건너뛰기




Volumn 283, Issue 2-3, 2011, Pages 129-139

Involvement of both intrinsic and extrinsic pathways in hepatoprotection of arjunolic acid against cadmium induced acute damage in vitro

Author keywords

Antioxidant; Apoptosis; Arjunolic acid; Cadmium; Cell survival; NF B; Oxidative stress; Reactive oxygen species

Indexed keywords

ALANINE AMINOTRANSFERASE; ARJUNOLIC ACID; ASPARTATE AMINOTRANSFERASE; CADMIUM; CADMIUM CHLORIDE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; GLUTATHIONE; GLUTATHIONE DISULFIDE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SAPONIN; UNCLASSIFIED DRUG;

EID: 79954667347     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2011.03.006     Document Type: Article
Times cited : (72)

References (62)
  • 1
    • 0030825717 scopus 로고    scopus 로고
    • NF-IL6 and NF-kB in cytokine gene regulation
    • Akira S., Kishimoto T. NF-IL6 and NF-kB in cytokine gene regulation. Adv. Immunol. 1997, 65:1-46.
    • (1997) Adv. Immunol. , vol.65 , pp. 1-46
    • Akira, S.1    Kishimoto, T.2
  • 2
    • 0000105994 scopus 로고    scopus 로고
    • Preotestive effect of Picrorrhiza kurroa on mitochondrial glutathione antioxidant system in d-galactodsamine induced hepatitis in rats
    • Anandan R., Rekha D.R., Debaki T. Preotestive effect of Picrorrhiza kurroa on mitochondrial glutathione antioxidant system in d-galactodsamine induced hepatitis in rats. Curr. Sci. 1999, 76:1543-1545.
    • (1999) Curr. Sci. , vol.76 , pp. 1543-1545
    • Anandan, R.1    Rekha, D.R.2    Debaki, T.3
  • 3
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14:649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 5
    • 77957185982 scopus 로고
    • Production of metalothionein and heat-shock proteins in response to metals
    • Bauman J.W., Liu J., Klaassen C.D. Production of metalothionein and heat-shock proteins in response to metals. Fund. Appl. Toxicol. 1993, 21:122-129.
    • (1993) Fund. Appl. Toxicol. , vol.21 , pp. 122-129
    • Bauman, J.W.1    Liu, J.2    Klaassen, C.D.3
  • 6
  • 7
    • 33845234243 scopus 로고    scopus 로고
    • Protein isolate from the herb, Phyllanthus niruri, modulates carbon tetrachloride-induced cytotoxicity in hepatocytes
    • Bhattacharjee R., Sil P.C. Protein isolate from the herb, Phyllanthus niruri, modulates carbon tetrachloride-induced cytotoxicity in hepatocytes. Toxicol. Mech. Methods 2006, 17:41-47.
    • (2006) Toxicol. Mech. Methods , vol.17 , pp. 41-47
    • Bhattacharjee, R.1    Sil, P.C.2
  • 8
    • 33947506805 scopus 로고    scopus 로고
    • Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties
    • Bhattacharjee R., Sil P.C. Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Food Chem. Toxicol. 2007, 45:817-826.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 817-826
    • Bhattacharjee, R.1    Sil, P.C.2
  • 9
    • 0025743868 scopus 로고
    • Relation between carcinogenesis, chromatin structure and poly (ADP-ribosylation)
    • Boulikas T. Relation between carcinogenesis, chromatin structure and poly (ADP-ribosylation). Anti Cancer Res. 1991, 11:489-527.
    • (1991) Anti Cancer Res. , vol.11 , pp. 489-527
    • Boulikas, T.1
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 11
    • 0024452911 scopus 로고
    • Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver
    • Campos R., Gorrido A., Guerra R., Valenznela A. Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver. Planta Med. 1989, 55:417-419.
    • (1989) Planta Med. , vol.55 , pp. 417-419
    • Campos, R.1    Gorrido, A.2    Guerra, R.3    Valenznela, A.4
  • 12
    • 0037200774 scopus 로고    scopus 로고
    • Molecular inhibitory mechanisms of antioxidant enzymes in rat liver and kidney by cadmium
    • Casalino E., Calzaretti G., Sblano C., Landriscina C. Molecular inhibitory mechanisms of antioxidant enzymes in rat liver and kidney by cadmium. Toxicology 2002, 179:37-50.
    • (2002) Toxicology , vol.179 , pp. 37-50
    • Casalino, E.1    Calzaretti, G.2    Sblano, C.3    Landriscina, C.4
  • 13
    • 33646518570 scopus 로고    scopus 로고
    • Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress
    • Chatterjee M., Sarkar K., Sil P.C. Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress. Pathophysiology 2006, 13:95-102.
    • (2006) Pathophysiology , vol.13 , pp. 95-102
    • Chatterjee, M.1    Sarkar, K.2    Sil, P.C.3
  • 14
    • 33847029863 scopus 로고    scopus 로고
    • Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo
    • Chatterjee M., Sil P.C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Indian J. Biochem. Biophys. 2006, 43:299-305.
    • (2006) Indian J. Biochem. Biophys. , vol.43 , pp. 299-305
    • Chatterjee, M.1    Sil, P.C.2
  • 15
    • 0021736856 scopus 로고
    • Andrographolide and kalmegh (Andrographis paniculata) extract: in vivo and in vitro effect on hepatic lipid peroxidation
    • Choudhuri B.R., Poddar M.K. Andrographolide and kalmegh (Andrographis paniculata) extract: in vivo and in vitro effect on hepatic lipid peroxidation. Methods Find Exp. Clin. Pharmacol. 1984, 6:481-485.
    • (1984) Methods Find Exp. Clin. Pharmacol. , vol.6 , pp. 481-485
    • Choudhuri, B.R.1    Poddar, M.K.2
  • 16
    • 77249177588 scopus 로고    scopus 로고
    • Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1
    • Das J., Ghosh J., Manna P., Sil P.C. Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1. Free Radic. Res. 2010, 44:340-355.
    • (2010) Free Radic. Res. , vol.44 , pp. 340-355
    • Das, J.1    Ghosh, J.2    Manna, P.3    Sil, P.C.4
  • 18
    • 0025127633 scopus 로고
    • Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal
    • Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990, 186:407-421.
    • (1990) Methods Enzymol. , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 19
    • 33645295199 scopus 로고    scopus 로고
    • Protective effect of a 43kD protein from the leaves of the herb, Cajanus indicus L on chloroform induced hepatic-disorder
    • Ghosh A., Sarkar K., Sil P.C. Protective effect of a 43kD protein from the leaves of the herb, Cajanus indicus L on chloroform induced hepatic-disorder. J. Biochem. Mol. Biol. 2006, 39:197-207.
    • (2006) J. Biochem. Mol. Biol. , vol.39 , pp. 197-207
    • Ghosh, A.1    Sarkar, K.2    Sil, P.C.3
  • 20
    • 57649155739 scopus 로고    scopus 로고
    • Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein
    • Ghosh A., Sil P.C. Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein. Chem. Biol. Interact. 2009, 177:96-106.
    • (2009) Chem. Biol. Interact. , vol.177 , pp. 96-106
    • Ghosh, A.1    Sil, P.C.2
  • 21
    • 36949026481 scopus 로고    scopus 로고
    • Anti-oxidative effect of a protein from Cajanus indicus L. against acetaminophen-induced hepato-nephro toxicity
    • Ghosh A., Sil P.C. Anti-oxidative effect of a protein from Cajanus indicus L. against acetaminophen-induced hepato-nephro toxicity. J. Biochem. Mol. Biol. 2007, 39:1039-1049.
    • (2007) J. Biochem. Mol. Biol. , vol.39 , pp. 1039-1049
    • Ghosh, A.1    Sil, P.C.2
  • 22
    • 55349110243 scopus 로고    scopus 로고
    • Cytoprotective effect of arjunolic acid in response to sodium fluoride mediated oxidative stress and cell death via necrotic pathway
    • Ghosh J., Das J., Manna P., Sil.P.C. Cytoprotective effect of arjunolic acid in response to sodium fluoride mediated oxidative stress and cell death via necrotic pathway. Toxicol. In Vitro 2008, 22:1918-1926.
    • (2008) Toxicol. In Vitro , vol.22 , pp. 1918-1926
    • Ghosh, J.1    Das, J.2    Manna, P.3    Sil, P.C.4
  • 23
    • 77954952873 scopus 로고    scopus 로고
    • Protective effect of the fruits of Terminalia arjuna against cadmium-induced oxidant stress and hepatic cell injury via MAPK activation and mitochondria dependent pathway
    • Ghosh J., Das J., Manna P., Sil P.C. Protective effect of the fruits of Terminalia arjuna against cadmium-induced oxidant stress and hepatic cell injury via MAPK activation and mitochondria dependent pathway. Food Chem. 2010, 123:1062-1075.
    • (2010) Food Chem. , vol.123 , pp. 1062-1075
    • Ghosh, J.1    Das, J.2    Manna, P.3    Sil, P.C.4
  • 24
    • 74149094986 scopus 로고    scopus 로고
    • Acetaminophen induced renal injury via oxidative stress and TNF-alpha production: therapeutic potential of arjunolic acid
    • Ghosh J., Das J., Manna P., Sil P.C. Acetaminophen induced renal injury via oxidative stress and TNF-alpha production: therapeutic potential of arjunolic acid. Toxicology 2010, 268:8-18.
    • (2010) Toxicology , vol.268 , pp. 8-18
    • Ghosh, J.1    Das, J.2    Manna, P.3    Sil, P.C.4
  • 25
    • 74249119041 scopus 로고    scopus 로고
    • Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection
    • Ghosh J., Das J., Manna P., Sil P.C. Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection. Free Radic. Biol. Med. 2010, 48:535-553.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 535-553
    • Ghosh, J.1    Das, J.2    Manna, P.3    Sil, P.C.4
  • 28
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin P.J., Hilf R.A. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 1976, 74:214-226.
    • (1976) Anal. Biochem. , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.A.2
  • 30
    • 33750021428 scopus 로고    scopus 로고
    • Aqueous extract of Terminalia arjuna prevents carbon tetrachloride induced hepatic and renal disorders
    • Manna P., Sinha M., Sil P.C. Aqueous extract of Terminalia arjuna prevents carbon tetrachloride induced hepatic and renal disorders. BMC Complement. Altern. Med. 2006, 6:33.
    • (2006) BMC Complement. Altern. Med. , vol.6 , pp. 33
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 31
    • 36048966054 scopus 로고    scopus 로고
    • Arjunolic acid, a triterpenoid saponin, ameliorates arsenic-induced cyto-toxicity in hepatocytes
    • Manna P., Sinha M., Sil.P.C. Arjunolic acid, a triterpenoid saponin, ameliorates arsenic-induced cyto-toxicity in hepatocytes. Chem. Biol. Interact. 2007, 170:187-200.
    • (2007) Chem. Biol. Interact. , vol.170 , pp. 187-200
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 32
    • 34147136101 scopus 로고    scopus 로고
    • Galactosamine-induced hepatotoxic effect and hepatoprotective role of a protein isolated from the herb Cajanus indicus L in vivo
    • Manna P., Sinha M., Sil P.C. Galactosamine-induced hepatotoxic effect and hepatoprotective role of a protein isolated from the herb Cajanus indicus L in vivo. J. Biochem. Mol. Toxicol. 2007, 21:13-23.
    • (2007) J. Biochem. Mol. Toxicol. , vol.21 , pp. 13-23
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 33
    • 35148819808 scopus 로고    scopus 로고
    • Phytomedicinal activity of Terminalia arjuna against carbon tetrachloride induced cardiac oxidative stress
    • Manna P., Sinha M., Sil P.C. Phytomedicinal activity of Terminalia arjuna against carbon tetrachloride induced cardiac oxidative stress. Pathophysiology 2007, 14:71-78.
    • (2007) Pathophysiology , vol.14 , pp. 71-78
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 34
    • 34848924674 scopus 로고    scopus 로고
    • Protection of arsenic-induced hepatic disorder by arjunolic acid
    • Manna P., Sinha M., Sil P.C. Protection of arsenic-induced hepatic disorder by arjunolic acid. Basic Clin. Pharmacol. Toxicol. 2007, 101:333-338.
    • (2007) Basic Clin. Pharmacol. Toxicol. , vol.101 , pp. 333-338
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 35
    • 41949118394 scopus 로고    scopus 로고
    • Protection of arsenic-induced testicular oxidative stress by arjunolic acid
    • Manna P., Sinha M., Sil P.C. Protection of arsenic-induced testicular oxidative stress by arjunolic acid. Redox Rep. 2008, 13:67-77.
    • (2008) Redox Rep. , vol.13 , pp. 67-77
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 36
    • 41849147561 scopus 로고    scopus 로고
    • Arsenic induced oxidative myocardial injury: protective role of arjunolic acid
    • Manna P., Sinha M., Sil P.C. Arsenic induced oxidative myocardial injury: protective role of arjunolic acid. Arch. Toxicol. 2008, 82:137-149.
    • (2008) Arch. Toxicol. , vol.82 , pp. 137-149
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 37
    • 70349172654 scopus 로고    scopus 로고
    • Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades
    • Manna P., Sinha M., Sil P.C. Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades. Chem. Biol. Interact. 2009, 181:297-308.
    • (2009) Chem. Biol. Interact. , vol.181 , pp. 297-308
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 38
    • 58649116450 scopus 로고    scopus 로고
    • Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways
    • Manna P., Sinha M., Sil P.C. Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways. Toxicology 2009, 257:53-63.
    • (2009) Toxicology , vol.257 , pp. 53-63
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 39
    • 77952551952 scopus 로고    scopus 로고
    • Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IκBα/NF-κB, MAPKs, and mitochondria-dependent prophylactic role of arjunolic acid
    • Manna P., Das J., Ghosh J., Sil P.C. Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IκBα/NF-κB, MAPKs, and mitochondria-dependent prophylactic role of arjunolic acid. Free Radic. Biol. Med. 2010, 48:1465-1484.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 1465-1484
    • Manna, P.1    Das, J.2    Ghosh, J.3    Sil, P.C.4
  • 40
    • 77950052431 scopus 로고    scopus 로고
    • Streptozotocin induced activation of oxidative stress responsive splenic cell signaling pathways: protective role of arjunolic acid
    • Manna P., Ghosh J., Das.J., Sil P.C. Streptozotocin induced activation of oxidative stress responsive splenic cell signaling pathways: protective role of arjunolic acid. Toxicol. Appl. Pharmacol. 2010, 244:114-129.
    • (2010) Toxicol. Appl. Pharmacol. , vol.244 , pp. 114-129
    • Manna, P.1    Ghosh, J.2    Das, J.3    Sil, P.C.4
  • 41
    • 51649098557 scopus 로고    scopus 로고
    • Biological activity of two related triterpenes isolated from Combretum nelsonii (Combretaceae) leaves
    • Masoko P., Mdee L.K., Mampuru L.J., Eloff J.N. Biological activity of two related triterpenes isolated from Combretum nelsonii (Combretaceae) leaves. Nat. Prod. Res. 2008, 22:1074-1084.
    • (2008) Nat. Prod. Res. , vol.22 , pp. 1074-1084
    • Masoko, P.1    Mdee, L.K.2    Mampuru, L.J.3    Eloff, J.N.4
  • 43
    • 0026443972 scopus 로고
    • Silymarin protectsagainst paracetamol-induced lipid peroxidation and liver damage
    • Muriel P., Garciapina T., Perez-Alvarez V., Mourelle M. Silymarin protectsagainst paracetamol-induced lipid peroxidation and liver damage. J. Appl. Toxicol. 1992, 12:439-442.
    • (1992) J. Appl. Toxicol. , vol.12 , pp. 439-442
    • Muriel, P.1    Garciapina, T.2    Perez-Alvarez, V.3    Mourelle, M.4
  • 45
    • 0141703513 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
    • Sakurai H., Suzuki S., Kawasaki N., Nakano H., Okazaki T., Chino A., Doi T., Saiki I. Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J. Biol. Chem. 2003, 278:36916-36923.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36916-36923
    • Sakurai, H.1    Suzuki, S.2    Kawasaki, N.3    Nakano, H.4    Okazaki, T.5    Chino, A.6    Doi, T.7    Saiki, I.8
  • 46
    • 26844536594 scopus 로고    scopus 로고
    • Preventive and curative role of a 43kDa protein from the leaves of the herb Cajanus indicus L on thioacetamide-induced hepatotoxicity in vivo
    • Sarkar K., Ghosh A., Sil P.C. Preventive and curative role of a 43kDa protein from the leaves of the herb Cajanus indicus L on thioacetamide-induced hepatotoxicity in vivo. Hepatol. Res. 2005, 33:39-49.
    • (2005) Hepatol. Res. , vol.33 , pp. 39-49
    • Sarkar, K.1    Ghosh, A.2    Sil, P.C.3
  • 47
    • 79954782663 scopus 로고    scopus 로고
    • A 43kDa protein from the herb Cajanus indicus L. protects thioacetamide induced cytotoxicity in hepatocytes
    • Sarkar K., Sil P.C. A 43kDa protein from the herb Cajanus indicus L. protects thioacetamide induced cytotoxicity in hepatocytes. Toxicol. In Vitro 2006, 206:34-640.
    • (2006) Toxicol. In Vitro , vol.206 , pp. 34-640
    • Sarkar, K.1    Sil, P.C.2
  • 48
    • 33750029509 scopus 로고    scopus 로고
    • Purification and characterization of a 43kDa hepatoprotective protein from the herb Cajanus indicus L
    • Sarkar K., Ghosh A., Kinter M., Mazumder B., Sil P.C. Purification and characterization of a 43kDa hepatoprotective protein from the herb Cajanus indicus L. Protein J. 2006, 25:411-421.
    • (2006) Protein J. , vol.25 , pp. 411-421
    • Sarkar, K.1    Ghosh, A.2    Kinter, M.3    Mazumder, B.4    Sil, P.C.5
  • 49
    • 34250799727 scopus 로고    scopus 로고
    • Attenuation of acetaminophen-induced hepatotoxicity in vivo and in vitro by a 43kDa protein from the herb Cajanus indicus L
    • Sarkar K., Sil P.C. Attenuation of acetaminophen-induced hepatotoxicity in vivo and in vitro by a 43kDa protein from the herb Cajanus indicus L. Toxicol. Mech. Methods 2007, 17:305-315.
    • (2007) Toxicol. Mech. Methods , vol.17 , pp. 305-315
    • Sarkar, K.1    Sil, P.C.2
  • 50
    • 35048894799 scopus 로고    scopus 로고
    • Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity
    • Sarkar M.K., Sil P.C. Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity. Pathophysiology 2007, 14:113-120.
    • (2007) Pathophysiology , vol.14 , pp. 113-120
    • Sarkar, M.K.1    Sil, P.C.2
  • 51
    • 60549112350 scopus 로고    scopus 로고
    • Purification and characterization of a novel antioxidant protein molecule from Phyllanthus niruri
    • Sarkar M.K., Kinter M., Mazumder B., Sil P.C. Purification and characterization of a novel antioxidant protein molecule from Phyllanthus niruri. Food Chem. 2009, 114:1405-1412.
    • (2009) Food Chem. , vol.114 , pp. 1405-1412
    • Sarkar, M.K.1    Kinter, M.2    Mazumder, B.3    Sil, P.C.4
  • 52
    • 77956098145 scopus 로고    scopus 로고
    • Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri
    • Sarkar M.K., Sil P.C. Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri. Toxicol. In Vitro 2010, 24:1711-1719.
    • (2010) Toxicol. In Vitro , vol.24 , pp. 1711-1719
    • Sarkar, M.K.1    Sil, P.C.2
  • 53
    • 34548827336 scopus 로고    scopus 로고
    • Aqueous extract of the bark of Terminalia arjuna plays protective role against sodium fluoride induced hepatic and renal oxidative stress
    • Sinha M., Manna P., Sil P.C. Aqueous extract of the bark of Terminalia arjuna plays protective role against sodium fluoride induced hepatic and renal oxidative stress. J. Nat. Med. 2007, 61:251-260.
    • (2007) J. Nat. Med. , vol.61 , pp. 251-260
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 54
    • 34249012855 scopus 로고    scopus 로고
    • Amelioration of galactosamine-induced nephrotoxicity by a protein isolated from the leaves of the herb, Cajanus indicus L.
    • Sinha M., Manna P., Sil P.C. Amelioration of galactosamine-induced nephrotoxicity by a protein isolated from the leaves of the herb, Cajanus indicus L. BMC Complement. Altern. Med. 2007, 7:11.
    • (2007) BMC Complement. Altern. Med. , vol.7 , pp. 11
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 55
    • 34250812738 scopus 로고    scopus 로고
    • Attenuation of cadmium chloride induced cytotoxicity in murine hepatocytes by a protein isolated from the leaves of the herb Cajanus indicus L
    • Sinha M., Manna P., Sil P.C. Attenuation of cadmium chloride induced cytotoxicity in murine hepatocytes by a protein isolated from the leaves of the herb Cajanus indicus L. Arch. Toxicol. 2007, 81:397-406.
    • (2007) Arch. Toxicol. , vol.81 , pp. 397-406
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 56
    • 36148938763 scopus 로고    scopus 로고
    • Taurine, a conditionally essential amino acid, ameliorates arsenic-induced cytotoxicity in murine hepatocytes
    • Sinha M., Manna P., Sil P.C. Taurine, a conditionally essential amino acid, ameliorates arsenic-induced cytotoxicity in murine hepatocytes. Toxicol. In Vitro 2007, 21:1419-1427.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 1419-1427
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 57
    • 58649115650 scopus 로고    scopus 로고
    • Arjunolic acid attenuates arsenic-induced nephroptxicity
    • Sinha M., Manna P., Sil P.C. Arjunolic acid attenuates arsenic-induced nephroptxicity. Pathophysiology 2008, 15:147-156.
    • (2008) Pathophysiology , vol.15 , pp. 147-156
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 58
    • 40449143072 scopus 로고    scopus 로고
    • Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain
    • Sinha M., Manna P., Sil P.C. Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain. J. Biochem. Mol. Toxicol. 2008, 22:15-26.
    • (2008) J. Biochem. Mol. Toxicol. , vol.22 , pp. 15-26
    • Sinha, M.1    Manna, P.2    Sil, P.C.3
  • 59
    • 0021763962 scopus 로고
    • Free radical mechanism in tissue injury
    • Slater T.F. Free radical mechanism in tissue injury. Biochem. J. 1984, 222:1-15.
    • (1984) Biochem. J. , vol.222 , pp. 1-15
    • Slater, T.F.1
  • 60
    • 0027480753 scopus 로고
    • Covalent attachment of 4-hydroxynonenal to glyceraldehydes-3-phosphate dehydrogenase
    • Uchida K., Stadtman E.R. Covalent attachment of 4-hydroxynonenal to glyceraldehydes-3-phosphate dehydrogenase. J. Biol. Chem. 1993, 268:6388-6393.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6388-6393
    • Uchida, K.1    Stadtman, E.R.2
  • 61
    • 0002956927 scopus 로고    scopus 로고
    • Cadmim carcinogenicity and genotoxicity
    • CRC Press, Boca Raton, FL, L.W. Chang (Ed.)
    • Waalkes M.P., Misra R.R. Cadmim carcinogenicity and genotoxicity. Toxicology of Metals 1996, 221-229. CRC Press, Boca Raton, FL. L.W. Chang (Ed.).
    • (1996) Toxicology of Metals , pp. 221-229
    • Waalkes, M.P.1    Misra, R.R.2
  • 62
    • 20544441245 scopus 로고    scopus 로고
    • Activator protein-1 (AP-1) DNA binding activity is induced by hydroxyurea in organogenesis stage mouse embryos
    • Yan J., Hales B.F. Activator protein-1 (AP-1) DNA binding activity is induced by hydroxyurea in organogenesis stage mouse embryos. Toxicol. Sci. 2005, 85:1013-1023.
    • (2005) Toxicol. Sci. , vol.85 , pp. 1013-1023
    • Yan, J.1    Hales, B.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.