Activator protein-1 (AP-1) DNA binding activity is induced by hydroxyurea in organogenesis stage mouse embryos

Toxicological Sciences

Volumn 85, Issue 2, 2005, Pages 1013-1023

  Yan, Jin ^a   Hales, Barbara F ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

c Fos; c Jun; Glutathione; Oxidative stress; Redox sensitive transcription factor; Teratogen

Indexed keywords

BIOLOGICAL MARKER; DNA; GLUTATHIONE; HYDROXYUREA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C FOS; PROTEIN C JUN; SODIUM CHLORIDE; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONGENITAL MALFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYOTOXICITY; EXPOSURE; FETUS DEVELOPMENT; FETUS RESORPTION; GENE EXPRESSION REGULATION; GESTATIONAL AGE; HEMIMELIA; IMMUNOREACTIVITY; LIMB MALFORMATION; MOUSE; NONHUMAN; ORGANOGENESIS; OXIDATIVE STRESS; PHOCOMELIA; PREGNANCY; PROGENY; PROTEIN DNA BINDING; PROTEIN INDUCTION; RIB MALFORMATION; TAIL; TERATOGENICITY; YOLK SAC;

ANIMALS; BONE AND BONES; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMBRYONIC DEVELOPMENT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUTATHIONE; HOMEOSTASIS; HYDROXYUREA; IMMUNOHISTOCHEMISTRY; MICE; NF-KAPPA B; OXIDATIVE STRESS; PREGNANCY; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-FOS; TERATOGENS; TRANSCRIPTION FACTOR AP-1;

EID: 20544441245     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi148     Document Type: Article

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