Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde

Toxicology and Applied Pharmacology

Volumn 252, Issue 3, 2011, Pages 307-317

  Zhang, Bo ^a   Huang, Bo ^a,b   Guan, Hua ^a   Zhang, Shi Meng ^a   Xu, Qin Zhi ^a   He, Xing Peng ^b   Liu, Xiao Dan ^a   Wang, Yu ^a   Shang, Zeng Fu ^a   Zhou, Ping Kun ^a,b  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Cell cycle arrest; DNA damage; Microtubule; Mitotic catastrophe; Spindle assembly; Therapeutic target; Vanillin derivative

Indexed keywords

6 BROMINE 5 HYDROXY 4 METHOXYBENZALDEHYDE; BENZALDEHYDE DERIVATIVE; CYCLIN E; HEAT SHOCK PROTEIN 70; PROTEIN 14 3 3; PROTEIN KINASE; TUBULIN; UNCLASSIFIED DRUG; VANILLIN;

ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL DEATH; CELL STRAIN HEPG2; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DISASTER; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; FLOW CYTOMETRY; HEPATOMA CELL; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MACROMOLECULE; MICROTUBULE; MITOSIS; MITOSIS INHIBITION; MULTINUCLEAR CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; PULSED FIELD GEL ELECTROPHORESIS; SIGNAL TRANSDUCTION; SPINDLE CELL; UPREGULATION;

APOPTOSIS; BENZALDEHYDES; CELL CYCLE; COMET ASSAY; DNA DAMAGE; FLOW CYTOMETRY; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOSIS; PROTEOMICS;

EID: 79954630643     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.03.003     Document Type: Article

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