Mitotic catastrophe is the predominant response to histone acetyltransferase depletion

Cell Death and Differentiation

Volumn 16, Issue 3, 2009, Pages 483-497

  Ha, G H ^a   Kim, H S ^a   Lee, C G ^a   Park, H Y ^a   Kim, E J ^a   Shin, H J ^a   Lee, J C ^a   Lee, K W ^b   Lee, C W ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CONDENSIN; DOUBLE STRANDED DNA; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H2AX; PROTEIN SUBUNIT; SHORT HAIRPIN RNA;

ANEUPLOIDY; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL DEATH; CELL MATURATION; CELL NUCLEUS; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; GROWTH REGULATION; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL CYCLE PROTEINS; CELL LINE, TUMOR; HELA CELLS; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; MITOSIS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 60849107272     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2008.182     Document Type: Article

References (39)

1. Ura K, Kurumizaka H, Dimitrov S, Almouzni G, Wolffe AP. Histone acetylation: Influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression. EMBO J 1997; 16: 2096-2107.
2. Lee KK, Workman JL. Histone acetyltransferase complexes: One size doesn't fit all. Nat Rev Mol Cell Biol 2007; 8: 284-295.
3. Cimini D, Mattiuzzo M, Torosantucci L, Degrassi F. Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. Mol Biol Cell 2003; 14 3821-3833.
4. Shin HJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC et al. Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. Oncogene 2003; 22: 3853-3858.
5. Stevens FE, Beamish H, Warrener R, Gabrielli B. Histone deacetylase inhibitors induce mitotic slippage. Oncogene 2008; 27: 1345-1354.
6. Taddei A, Maison C, Roche D, Almouzni G. Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. Nat Cell Biol 2001; 3: 114-120.
7. Shin HJ, Baek KH, Jeon AH, Park MT, Lee SJ, Kang CM et al. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell 2003; 4: 483-497.
8. Lampson MA, Renduchitala K, Khodjakov A, Kapoor TM. Correcting improper chromosome-spindle attachments during cell division. Nat Cell Biol 2004; 6: 232-237.
9. Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W et al. MAD2 haploinsufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 2001; 409: 355-359.
10. Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: Aneuploidy and the mitotic checkpoint. Nat Rev Cancer 2005; 5: 773-785.
11. Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH et al. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2008; Oct: 10.
12. Ricci MS, Zong WX. Chemotherapeutic approaches for targeting cell death pathways. Oncologist 2006; 11: 342-357.
13. Castedo M, Perfettini JL, Roumier T, Andreau K, Medema R, Kroemer G. Cell death by mitotic catastrophe: A molecular definition. Oncogene 2004; 23: 2825-2837.
14. Tsai MS, Lee JL, Chang YJ, Hwang SM. Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum Reprod 2004; 19: 1450-1456.
15. Yoshimura K, Shigeura T, Matsumoto D, Sato T, Takaki Y, Aiba-Kojima E et al. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol 2006; 208: 64-76.
16. Redon C, Pilch D, Rogakou E, Sedelnikova O, Newrock K, Bonner W. Histone H2A variants H2AX and H2AZ. Curr Opin Genet Dev 2002; 12: 162-169.
17. Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999; 146: 905-916.
18. Ichijima Y, Sakasai R, Okita N, Asahina K, Mizutani S, Teraoka H. Phosphorylation of histone H2AX at M phase in human cells without DNA damage response. Biochem Biophys Res Commun 2005; 336: 807-812.
19. Fernandez-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM et al. H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell 2003; 4: 497-508.
20. Rainey MD, Black EJ, Zachos G, Gillespie DA. Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase. Oncogene 2008; 27: 896-906.
21. Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M. Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe. J Biol Chem 2005; 280: 39246-39252.
22. Lu C, Zhu F, Cho YY, Tang F, Zykova T, Ma WY et al. Cell apoptosis: Requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3. Mol Cell 2006; 23: 121-132.
23. Hirota T, Lipp JJ, Toh BH, Peters JM. Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature 2005; 438: 1176-1180.
24. Kireeva N, Lakonishok M, Kireev I, Hirano T, Belmont AS. Visualization of early chromosome condensation: A hierarchical folding, axial glue model of chromosome structure. J Cell Biol 2004; 166: 775-785.
25. Belmont AS. Mitotic chromosome structure and condensation. Curr Opin Cell Biol 2006; 18: 632-638.
26. Maeshima K, Laemmli UK. A two-step scaffolding model for mitotic chromosome assembly. Dev Cell 2003; 4: 467-480.
27. Hudson DF, Vagnarelli P, Gassmann R, Earnshaw WC. Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev Cell 2003; 5: 323-336.
28. Bazett-Jones DP, Kimura K, Hirano T. Efficient supercoiling of DNA by a single condensin complex as revealed by electron spectroscopic imaging. Mol Cell 2002; 9: 1183-1190.
29. Strick TR, Kawaguchi T, Hirano T. Real-time detection of single-molecule DNA compaction by condensin I. Curr Biol 2004; 14: 874-880.
30. Wang BD, Eyre D, Basrai M, Lichten M, Strunnikov A. Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome. Mol Cell Biol 2005; 25: 7216-7225.
31. McManus KJ, Hendzel MJ. The relationship between histone H3 phosphorylation and acetylation throughout the mammalian cell cycle. Biochem Cell Biol 2006; 84: 640-657.
32. McGowan CH, Russell P. The DNA damage response: Sensing and signaling. Curr Opin Cell Biol 2004; 16: 629-633.
33. Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421 499-506.
34. Hirano T. At the heart of the chromosome: SMC proteins in action. Nat Rev Mol Cell Biol 2006; 7: 311-322.
35. Yoshimura SH, Hizume K, Murakami A, Sutani T, Takeyasu K, Yanagida M. Condensin architecture and interaction with DNA: Regulatory non-SMC subunits bind to the head of SMC heterodimer. Curr Biol 2002; 12: 508-513.
36. Goto H, Tomono Y, Ajiro K, Kosako H, Fujita M, Sakurai M et al. Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. J Biol Chem 1999; 274: 25543-25549.
37. Li H, Cuenin C, Murr R, Wang ZQ, Herceg Z. HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression. EMBO J 2004; 23: 4824-4834.
38. Burgess A, Ruefli A, Beamish H, Warrener R, Saunders N, Johnstone R et al. Histone deacetylase inhibitors specifically kill nonproliferating tumour cells. Oncogene 2004; 23: 6693-6701.
39. Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 2007; 11: 25-36.