-
1
-
-
0031470835
-
Checkpoint pathways come of age
-
Nurse P. Checkpoint pathways come of age. Cell 1997; 91:865-7.
-
(1997)
Cell
, vol.91
, pp. 865-867
-
-
Nurse, P.1
-
2
-
-
0026657169
-
Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex
-
Gabrielli BG, Lee MS, Walker DH, Piwnica-Worms H, Maller JL. Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex. J Biol Chem 1992; 267:18040-6.
-
(1992)
J Biol Chem
, vol.267
, pp. 18040-18046
-
-
Gabrielli, B.G.1
Lee, M.S.2
Walker, D.H.3
Piwnica-Worms, H.4
Maller, J.L.5
-
3
-
-
0025936510
-
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
-
Gautier J, Solomon MJ, Booher RN, Bazan JF, Kirschner MW. cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell 1991; 67:197-211.
-
(1991)
Cell
, vol.67
, pp. 197-211
-
-
Gautier, J.1
Solomon, M.J.2
Booher, R.N.3
Bazan, J.F.4
Kirschner, M.W.5
-
5
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997; 277:1497-501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
6
-
-
0033552873
-
A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase
-
Blasina A, de Weyer IV, Laus MC, Luyten WH, Parker AE, McGowan CH. A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase. Curr Biol 1999; 9:1-10.
-
(1999)
Curr Biol
, vol.9
, pp. 1-10
-
-
Blasina, A.1
de Weyer, I.V.2
Laus, M.C.3
Luyten, W.H.4
Parker, A.E.5
McGowan, C.H.6
-
7
-
-
0029871708
-
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine
-
Muslin AJ, Tanner JW, Allen PM, Shaw AS. Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 1996; 84:889-97.
-
(1996)
Cell
, vol.84
, pp. 889-897
-
-
Muslin, A.J.1
Tanner, J.W.2
Allen, P.M.3
Shaw, A.S.4
-
8
-
-
0031470652
-
The structural basis for 14-3-3: Phosphopeptide binding specificity
-
Yaffe MB, Rittinger K, Volinia S, Caron PR, Aitken A, Leffers H, Gamblin SJ, Smerdon SJ, Cantley LC. The structural basis for 14-3-3: phosphopeptide binding specificity. Cell 1997; 91:961-71.
-
(1997)
Cell
, vol.91
, pp. 961-971
-
-
Yaffe, M.B.1
Rittinger, K.2
Volinia, S.3
Caron, P.R.4
Aitken, A.5
Leffers, H.6
Gamblin, S.J.7
Smerdon, S.J.8
Cantley, L.C.9
-
9
-
-
0032974109
-
Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site
-
Dalal SN, Schweitzer CM, Gan J, DeCaprio JA. Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site. Mol Cell Biol 1999; 19:4465-79.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4465-4479
-
-
Dalal, S.N.1
Schweitzer, C.M.2
Gan, J.3
DeCaprio, J.A.4
-
10
-
-
0035810050
-
Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding
-
Graves PR, Lovly CM, Uy GL, Piwnica-Worms H. Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Oncogene 2001; 20:1839-51.
-
(2001)
Oncogene
, vol.20
, pp. 1839-1851
-
-
Graves, P.R.1
Lovly, C.M.2
Uy, G.L.3
Piwnica-Worms, H.4
-
11
-
-
0028903288
-
14-3-3 proteins on the MAP
-
Aitken A. 14-3-3 proteins on the MAP. Trends Biochem Sci 1995; 20:95-7.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 95-97
-
-
Aitken, A.1
-
12
-
-
4644332282
-
14-3-3 Family Members Act Coordinately to Regulate Mitotic Progression
-
Dalal SN, Yaffe MB, DeCaprio JA. 14-3-3 Family Members Act Coordinately to Regulate Mitotic Progression. Cell Cycle 2004; 3.
-
(2004)
Cell Cycle
, pp. 3
-
-
Dalal, S.N.1
Yaffe, M.B.2
DeCaprio, J.A.3
-
13
-
-
0036141604
-
Identification of frequent G(2) checkpoint impairment and a homozygous deletion of 14-3-3epsilon at 17p13.3 in small cell lung cancers
-
Konishi H, Nakagawa T, Harano T, Mizuno K, Saito H, Masuda A, Matsuda H, Osada H, Takahashi T. Identification of frequent G(2) checkpoint impairment and a homozygous deletion of 14-3-3epsilon at 17p13.3 in small cell lung cancers. Cancer Res 2002; 62:271-6.
-
(2002)
Cancer Res
, vol.62
, pp. 271-276
-
-
Konishi, H.1
Nakagawa, T.2
Harano, T.3
Mizuno, K.4
Saito, H.5
Masuda, A.6
Matsuda, H.7
Osada, H.8
Takahashi, T.9
-
14
-
-
0030828073
-
2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
-
2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 1997; 106:348-60.
-
(1997)
Chromosoma
, vol.106
, pp. 348-360
-
-
Hendzel, M.J.1
Wei, Y.2
Mancini, M.A.3
Van Hooser, A.4
Ranalli, T.5
Brinkley, B.R.6
Bazett-Jones, D.P.7
Allis, C.D.8
-
15
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
16
-
-
0034326802
-
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
-
Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res 2000; 60:5934-6.
-
(2000)
Cancer Res
, vol.60
, pp. 5934-5936
-
-
Ahn, J.Y.1
Schwarz, J.K.2
Piwnica-Worms, H.3
Canman, C.E.4
-
17
-
-
0038013782
-
Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation
-
Gatei M, Sloper K, Sorensen C, Syljuasen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation. J Biol Chem 2003; 278:14806-11.
-
(2003)
J Biol Chem
, vol.278
, pp. 14806-14811
-
-
Gatei, M.1
Sloper, K.2
Sorensen, C.3
Syljuasen, R.4
Falck, J.5
Hobson, K.6
Savage, K.7
Lukas, J.8
Zhou, B.B.9
Bartek, J.10
Khanna, K.K.11
-
18
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
Chaturvedi P, Eng WK, Zhu Y, Mattern MR, Mishra R, Hurle MR, Zhang X, Annan RS, Lu Q, Faucette LF, Scott GF, Li X, Carr SA, Johnson RK, Winkler JD, Zhou BB. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 1999; 18:4047-54.
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
Eng, W.K.2
Zhu, Y.3
Mattern, M.R.4
Mishra, R.5
Hurle, M.R.6
Zhang, X.7
Annan, R.S.8
Lu, Q.9
Faucette, L.F.10
Scott, G.F.11
Li, X.12
Carr, S.A.13
Johnson, R.K.14
Winkler, J.D.15
Zhou, B.B.16
-
19
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998; 282:1893-7.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
20
-
-
0034641724
-
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci USA 2000; 97:10389-94.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10389-10394
-
-
Matsuoka, S.1
Rotman, G.2
Ogawa, A.3
Shiloh, Y.4
Tamai, K.5
Elledge, S.J.6
-
21
-
-
33646777679
-
Rapid activation of ATR by ionizing radiation requires ATM and Mre11
-
Myers JS, Cortez D. Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem 2006; 281:9346-50.
-
(2006)
J Biol Chem
, vol.281
, pp. 9346-9350
-
-
Myers, J.S.1
Cortez, D.2
-
22
-
-
0033616828
-
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
-
Brown AL, Lee CH, Schwarz JK, Mitiku N, Piwnica-Worms H, Chung JH. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci USA 1999; 96:3745-50.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3745-3750
-
-
Brown, A.L.1
Lee, C.H.2
Schwarz, J.K.3
Mitiku, N.4
Piwnica-Worms, H.5
Chung, J.H.6
-
23
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000; 10:886-95.
-
(2000)
Curr Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
24
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, Jeggo PA. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 2004; 64:2390-6.
-
(2004)
Cancer Res
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
25
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
26
-
-
0032190082
-
Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1
-
Zeng Y, Forbes KC, Wu Z, Moreno S, Piwnica-Worms H, Enoch T. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature 1998; 395:507-10.
-
(1998)
Nature
, vol.395
, pp. 507-510
-
-
Zeng, Y.1
Forbes, K.C.2
Wu, Z.3
Moreno, S.4
Piwnica-Worms, H.5
Enoch, T.6
-
27
-
-
0032746942
-
DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding
-
Zeng Y, Piwnica-Worms H. DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding. Mol Cell Biol 1999; 19:7410-9.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7410-7419
-
-
Zeng, Y.1
Piwnica-Worms, H.2
-
28
-
-
33751212191
-
Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
-
Margolis SS, Perry JA, Forester CM, Nutt LK, Guo Y, Jardim MJ, Thomenius MJ, Freel CD, Darbandi R, Ahn JH, Arroyo JD, Wang XF, Shenolikar S, Nairn AC, Dunphy WG, Hahn WC, Virshup DM, Kornbluth S. Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell 2006; 127:759-73.
-
(2006)
Cell
, vol.127
, pp. 759-773
-
-
Margolis, S.S.1
Perry, J.A.2
Forester, C.M.3
Nutt, L.K.4
Guo, Y.5
Jardim, M.J.6
Thomenius, M.J.7
Freel, C.D.8
Darbandi, R.9
Ahn, J.H.10
Arroyo, J.D.11
Wang, X.F.12
Shenolikar, S.13
Nairn, A.C.14
Dunphy, W.G.15
Hahn, W.C.16
Virshup, D.M.17
Kornbluth, S.18
-
29
-
-
33744994838
-
A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25
-
Margolis SS, Perry JA, Weitzel DH, Freel CD, Yoshida M, Haystead TA, Kornbluth S. A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25. Mol Biol Cell 2006; 17:1779-89.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 1779-1789
-
-
Margolis, S.S.1
Perry, J.A.2
Weitzel, D.H.3
Freel, C.D.4
Yoshida, M.5
Haystead, T.A.6
Kornbluth, S.7
-
30
-
-
0036847320
-
Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability
-
Mailand N, Podtelejnikov AV, Groth A, Mann M, Bartek J, Lukas J. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability. Embo J 2002; 21:5911-20.
-
(2002)
Embo J
, vol.21
, pp. 5911-5920
-
-
Mailand, N.1
Podtelejnikov, A.V.2
Groth, A.3
Mann, M.4
Bartek, J.5
Lukas, J.6
-
31
-
-
26444493574
-
Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome
-
Lindqvist A, Kallstrom H, Lundgren A, Barsoum E, Rosenthal CK. Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. J Cell Biol 2005; 171:35-45.
-
(2005)
J Cell Biol
, vol.171
, pp. 35-45
-
-
Lindqvist, A.1
Kallstrom, H.2
Lundgren, A.3
Barsoum, E.4
Rosenthal, C.K.5
-
32
-
-
0037804567
-
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
-
Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ Jr. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol 2003; 5:545-51.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 545-551
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Demidenko, Z.N.3
Meek, S.4
Graves, P.5
Phillips, C.6
Zhao, H.7
Moody, S.A.8
Appella, E.9
Piwnica-Worms, H.10
Fornace Jr., A.J.11
-
34
-
-
0034594961
-
Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase
-
Mils V, Baldin V, Goubin F, Pinta I, Papin C, Waye M, Eychene A, Ducommun B. Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase. Oncogene 2000; 19:1257-65.
-
(2000)
Oncogene
, vol.19
, pp. 1257-1265
-
-
Mils, V.1
Baldin, V.2
Goubin, F.3
Pinta, I.4
Papin, C.5
Waye, M.6
Eychene, A.7
Ducommun, B.8
-
35
-
-
0033533612
-
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
-
Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 1999; 401:616-20.
-
(1999)
Nature
, vol.401
, pp. 616-620
-
-
Chan, T.A.1
Hermeking, H.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
36
-
-
54049151401
-
Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis
-
In press
-
Kundu ST, Gosavi P, Khapare N, Patel R, Hosing AS, Maru GB, Ingle A, DeCaprio JA, Dalal SN. Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis. Intl J Cancer 1998; In press.
-
(1998)
Intl J Cancer
-
-
Kundu, S.T.1
Gosavi, P.2
Khapare, N.3
Patel, R.4
Hosing, A.S.5
Maru, G.B.6
Ingle, A.7
DeCaprio, J.A.8
Dalal, S.N.9
-
38
-
-
20744444075
-
Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development
-
Skaar JR, Arai T, DeCaprio JA. Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development. Mol Cell Biol 2005; 25:5579-89.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5579-5589
-
-
Skaar, J.R.1
Arai, T.2
DeCaprio, J.A.3
-
41
-
-
0034906435
-
Aneuploid colon cancer cells have a robust spindle checkpoint
-
Tighe A, Johnson VL, Albertella M, Taylor SS. Aneuploid colon cancer cells have a robust spindle checkpoint. EMBO Rep 2001; 2:609-14.
-
(2001)
EMBO Rep
, vol.2
, pp. 609-614
-
-
Tighe, A.1
Johnson, V.L.2
Albertella, M.3
Taylor, S.S.4
|