Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells

Journal of Surgical Research

Volumn 167, Issue 2, 2011, Pages 173-181

  Melstrom, Laleh G ^a   Salabat, Mohammad R ^a   Ding, Xian Zhong ^a   Strouch, Matthew J ^a   Grippo, Paul J ^a   Mirzoeva, Salida ^a   Pelling, Jill C ^a   Bentrem, David J ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

apigenin; GLUT 1; HIF 1 ; hypoxia; pancreatic cancer; VEGF

Indexed keywords

APIGENIN; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; VASCULOTROPIN;

ARTICLE; CANCER CELL; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ADENOCARCINOMA; AMINO ACIDS, DICARBOXYLIC; APIGENIN; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE TRANSPORTER TYPE 1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PANCREATIC NEOPLASMS; RNA, MESSENGER; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79954598113     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.10.041     Document Type: Article

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