Apigenin suppresses the expression of VEGF, an important factor for angiogenesis, in endothelial cells via degradation of HIF-1α protein

FEBS Letters

Volumn 575, Issue 1-3, 2004, Pages 59-63

  Osada, Mayuko ^a   Imaoka, Susumu ^b   Funae, Yoshihiko ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KWANSEI GAKUIN UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Apigenin; EPO, erythropoietin; Heat shock protein 90; HIF 1, hypoxia inducible factor 1; Hypoxia; Hypoxia inducible factor; pVHL, von Hippel Lindau protein; Vascular endothelial growth factor; VEGF, vascular endothelial growth factor

Indexed keywords

APIGENIN; ERYTHROPOIETIN; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UMBILICAL ARTERY;

ANGIOGENESIS INHIBITORS; ANIMALS; ANOXIA; ANTINEOPLASTIC AGENTS; APIGENIN; CELL LINE; COBALT; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 4544325479     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.08.036     Document Type: Article

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