Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension

Journal of Applied Physiology

Volumn 110, Issue 4, 2011, Pages 901-908

  Schwenke, Daryl O ^a   Pearson, James T ^b   Sonobe, Takashi ^c   Ishibashi Ueda, Hatsue ^c   Shimouchi, Akito ^c   Kangawa, Kenji ^c   Umetani, Keiji ^d   Shirai, Mikiyasu ^c  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b MONASH UNIVERSITY   (Australia)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

Author keywords

Pulmonary microvessels; Rat; Synchrotron radiation microangiography; Vasoconstriction

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ACETYLCHOLINE; DRUG DERIVATIVE; ENZYME INHIBITOR; FASUDIL; MONOCROTALINE; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; RHO KINASE; VASODILATOR AGENT;

ANGIOGRAPHY; ANIMAL; ARTICLE; BLOOD FLOW; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; LUNG; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PULMONARY HYPERTENSION; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASCULARIZATION; VASOCONSTRICTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACETYLCHOLINE; ANGIOGRAPHY; ANIMALS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYPERTENSION, PULMONARY; LUNG; MALE; MONOCROTALINE; NG-NITROARGININE METHYL ESTER; NITROPRUSSIDE; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 79954596642     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01318.2010     Document Type: Article

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