메뉴 건너뛰기




Volumn 10, Issue , 2009, Pages

Endothelial cells and pulmonary arterial hypertension: Apoptosis, proliferation, interaction and transdifferentiation

Author keywords

[No Author keywords available]

Indexed keywords

SEMAXANIB;

EID: 73949089232     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-10-95     Document Type: Review
Times cited : (184)

References (93)
  • 1
    • 0037151645 scopus 로고    scopus 로고
    • Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival
    • 10.1016/S0735-1097(02)02012-0, 12204511
    • Sitbon O, Humbert M, Nunes H, Parent F, Garcia G, Herve P, Rainisio M, Simonneau G. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol 2002, 40:780-788. 10.1016/S0735-1097(02)02012-0, 12204511.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 780-788
    • Sitbon, O.1    Humbert, M.2    Nunes, H.3    Parent, F.4    Garcia, G.5    Herve, P.6    Rainisio, M.7    Simonneau, G.8
  • 2
    • 0035969984 scopus 로고    scopus 로고
    • Inhaled nitric oxide versus aerosolized iloprost in secondary pulmonary hypertension in children with congenital heart disease: vasodilator capacity and cellular mechanisms
    • Rimensberger PC, Spahr-Schopfer I, Berner M, Jaeggi E, Kalangos A, Friedli B, Beghetti M. Inhaled nitric oxide versus aerosolized iloprost in secondary pulmonary hypertension in children with congenital heart disease: vasodilator capacity and cellular mechanisms. Circulation 2001, 103:544-548.
    • (2001) Circulation , vol.103 , pp. 544-548
    • Rimensberger, P.C.1    Spahr-Schopfer, I.2    Berner, M.3    Jaeggi, E.4    Kalangos, A.5    Friedli, B.6    Beghetti, M.7
  • 3
    • 0028282859 scopus 로고
    • Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension
    • 1887146, 7508683
    • Tuder RM, Groves B, Badesch DB, Voelkel NF. Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension. Am J Pathol 1994, 144:275-285. 1887146, 7508683.
    • (1994) Am J Pathol , vol.144 , pp. 275-285
    • Tuder, R.M.1    Groves, B.2    Badesch, D.B.3    Voelkel, N.F.4
  • 4
    • 0033912022 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors correlates closely with formation of the plexiform lesion in human pulmonary hypertension
    • 10.1046/j.1440-1827.2000.01068.x, 10886723
    • Hirose S, Hosoda Y, Furuya S, Otsuki T, Ikeda E. Expression of vascular endothelial growth factor and its receptors correlates closely with formation of the plexiform lesion in human pulmonary hypertension. Pathol Int 2000, 50:472-479. 10.1046/j.1440-1827.2000.01068.x, 10886723.
    • (2000) Pathol Int , vol.50 , pp. 472-479
    • Hirose, S.1    Hosoda, Y.2    Furuya, S.3    Otsuki, T.4    Ikeda, E.5
  • 5
  • 7
    • 0032777126 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth
    • 1866857, 10433934
    • Cool CD, Stewart JS, Werahera P, Miller GJ, Williams RL, Voelkel NF, Tuder RM. Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth. Am J Pathol 1999, 155:411-419. 1866857, 10433934.
    • (1999) Am J Pathol , vol.155 , pp. 411-419
    • Cool, C.D.1    Stewart, J.S.2    Werahera, P.3    Miller, G.J.4    Williams, R.L.5    Voelkel, N.F.6    Tuder, R.M.7
  • 8
    • 0036887580 scopus 로고    scopus 로고
    • Cells in focus: endothelial cell
    • 10.1016/S1357-2725(02)00075-4, 12379270
    • Sumpio BE, Riley JT, Dardik A. Cells in focus: endothelial cell. Int J Biochem Cell Biol 2002, 34:1508-1512. 10.1016/S1357-2725(02)00075-4, 12379270.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1508-1512
    • Sumpio, B.E.1    Riley, J.T.2    Dardik, A.3
  • 9
    • 0031821684 scopus 로고    scopus 로고
    • Mechanisms of proliferative and obliterative vascular diseases: insights from the pulmonary and systemic circulations. NHLBI Workshop summary
    • Fishman AP, Fishman MC, Freeman BA, Gimbrone MA, Rabinovitch M, Robinson D, Gail DB. Mechanisms of proliferative and obliterative vascular diseases: insights from the pulmonary and systemic circulations. NHLBI Workshop summary. Am J Respir Crit Care Med 1998, 158:670-674.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 670-674
    • Fishman, A.P.1    Fishman, M.C.2    Freeman, B.A.3    Gimbrone, M.A.4    Rabinovitch, M.5    Robinson, D.6    Gail, D.B.7
  • 10
    • 33748441793 scopus 로고    scopus 로고
    • Hypoxic pulmonary vasoconstriction is mediated by increased production of reactive oxygen species
    • 10.1152/japplphysiol.00480.2006, 16675614
    • Ward JP. Hypoxic pulmonary vasoconstriction is mediated by increased production of reactive oxygen species. J Appl Physiol 2006, 101:993-995. 10.1152/japplphysiol.00480.2006, 16675614.
    • (2006) J Appl Physiol , vol.101 , pp. 993-995
    • Ward, J.P.1
  • 11
    • 33750608201 scopus 로고    scopus 로고
    • Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species
    • 10.1152/japplphysiol.00480a.2006, 16902070
    • Weir EK, Archer SL. Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species. J Appl Physiol 2006, 101:995-998. 10.1152/japplphysiol.00480a.2006, 16902070.
    • (2006) J Appl Physiol , vol.101 , pp. 995-998
    • Weir, E.K.1    Archer, S.L.2
  • 12
    • 0038389113 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth
    • 10.1161/01.RES.0000073585.50092.14, 12714563
    • Ameshima S, Golpon H, Cool CD, Chan D, Vandivier RW, Gardai SJ, Wick M, Nemenoff RA, Geraci MW, Voelkel NF. Peroxisome proliferatoractivated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth. Circ Res 2003, 92:1162-1169. 10.1161/01.RES.0000073585.50092.14, 12714563.
    • (2003) Circ Res , vol.92 , pp. 1162-1169
    • Ameshima, S.1    Golpon, H.2    Cool, C.D.3    Chan, D.4    Vandivier, R.W.5    Gardai, S.J.6    Wick, M.7    Nemenoff, R.A.8    Geraci, M.W.9    Voelkel, N.F.10
  • 13
    • 1242320042 scopus 로고    scopus 로고
    • Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis
    • 10.1161/01.RES.0000112406.27800.6F, 14670836
    • Pi X, Yan C, Berk BC. Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ Res 2004, 94:362-369. 10.1161/01.RES.0000112406.27800.6F, 14670836.
    • (2004) Circ Res , vol.94 , pp. 362-369
    • Pi, X.1    Yan, C.2    Berk, B.C.3
  • 14
    • 33644865928 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
    • 10.1161/01.RES.0000200180.01710.e6, 16357305
    • Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA, Karoubi G, Courtman DW, Zucco L, Granton J, Stewart DJ. Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 2006, 98:209-217. 10.1161/01.RES.0000200180.01710.e6, 16357305.
    • (2006) Circ Res , vol.98 , pp. 209-217
    • Teichert-Kuliszewska, K.1    Kutryk, M.J.2    Kuliszewski, M.A.3    Karoubi, G.4    Courtman, D.W.5    Zucco, L.6    Granton, J.7    Stewart, D.J.8
  • 15
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • 10.1096/fj.00-0343com, 11156958
    • Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J 2001, 15:427-438. 10.1096/fj.00-0343com, 11156958.
    • (2001) FASEB J , vol.15 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6    Voelkel, N.F.7    Tuder, R.M.8
  • 16
    • 0035975944 scopus 로고    scopus 로고
    • Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension
    • 10.1161/hc4201.097838, 11684638
    • Campbell AI, Zhao Y, Sandhu R, Stewart DJ. Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension. Circulation 2001, 104:2242-2248. 10.1161/hc4201.097838, 11684638.
    • (2001) Circulation , vol.104 , pp. 2242-2248
    • Campbell, A.I.1    Zhao, Y.2    Sandhu, R.3    Stewart, D.J.4
  • 17
    • 0038554221 scopus 로고    scopus 로고
    • Protective role of angiopoietin-1 in experimental pulmonary hypertension
    • 10.1161/01.RES.0000070587.79937.F0, 12690034
    • Zhao YD, Campbell AI, Robb M, Ng D, Stewart DJ. Protective role of angiopoietin-1 in experimental pulmonary hypertension. Circ Res 2003, 92:984-991. 10.1161/01.RES.0000070587.79937.F0, 12690034.
    • (2003) Circ Res , vol.92 , pp. 984-991
    • Zhao, Y.D.1    Campbell, A.I.2    Robb, M.3    Ng, D.4    Stewart, D.J.5
  • 19
    • 21744460365 scopus 로고    scopus 로고
    • Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells
    • Sakao S, Taraseviciene-Stewart L, Lee JD, Wood K, Cool CD, Voelkel NF. Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells. FASEB J 2005, 19:1178-1180.
    • (2005) FASEB J , vol.19 , pp. 1178-1180
    • Sakao, S.1    Taraseviciene-Stewart, L.2    Lee, J.D.3    Wood, K.4    Cool, C.D.5    Voelkel, N.F.6
  • 21
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • 10.1126/science.7878464, 7878464
    • Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267:1456. 10.1126/science.7878464, 7878464.
    • (1995) Science , vol.267 , pp. 1456
    • Thompson, C.B.1
  • 22
    • 0035797881 scopus 로고    scopus 로고
    • Apoptotic cell removal
    • 10.1016/S0960-9822(01)00474-2, 11591341
    • Henson PM, Bratton DL, Fadok VA. Apoptotic cell removal. Curr Biol 2001, 11:R795-R805. 10.1016/S0960-9822(01)00474-2, 11591341.
    • (2001) Curr Biol , vol.11
    • Henson, P.M.1    Bratton, D.L.2    Fadok, V.A.3
  • 23
    • 0034795821 scopus 로고    scopus 로고
    • Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences
    • 200959, 11581295
    • Fadok VA, Bratton DL, Henson PM. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J Clin Invest 2001, 108:957-962. 200959, 11581295.
    • (2001) J Clin Invest , vol.108 , pp. 957-962
    • Fadok, V.A.1    Bratton, D.L.2    Henson, P.M.3
  • 24
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • 10.1038/35037722, 11048729
    • Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000, 407:784-788. 10.1038/35037722, 11048729.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 28
    • 7244242362 scopus 로고    scopus 로고
    • Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
    • 10.1182/blood-2004-04-1396, 15226175
    • Ingram DA, Mead LE, Tanaka H, Meade V, Fenoglio A, Mortell K, Pollok K, Ferkowicz MJ, Gilley D, Yoder MC. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004, 104:2752-2760. 10.1182/blood-2004-04-1396, 15226175.
    • (2004) Blood , vol.104 , pp. 2752-2760
    • Ingram, D.A.1    Mead, L.E.2    Tanaka, H.3    Meade, V.4    Fenoglio, A.5    Mortell, K.6    Pollok, K.7    Ferkowicz, M.J.8    Gilley, D.9    Yoder, M.C.10
  • 29
    • 15944381205 scopus 로고    scopus 로고
    • Vessel wall derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells
    • 10.1182/blood-2004-08-3057, 15585655
    • Ingram DA, Mead LE, Moore DB, Woodard W, Fenoglio A, Yoder MC. Vessel wall derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood 2005, 105:2783-2786. 10.1182/blood-2004-08-3057, 15585655.
    • (2005) Blood , vol.105 , pp. 2783-2786
    • Ingram, D.A.1    Mead, L.E.2    Moore, D.B.3    Woodard, W.4    Fenoglio, A.5    Yoder, M.C.6
  • 30
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • 10.1126/science.277.5323.242, 9211853
    • Lindahl P, Johansson BR, Levéen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 1997, 277:242-245. 10.1126/science.277.5323.242, 9211853.
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Levéen, P.3    Betsholtz, C.4
  • 31
    • 0032482202 scopus 로고    scopus 로고
    • PDGF, TGF-β and heterotypic cell-cell interactions mediate the recruitment and differentiation of 10T1/2 cells to a smooth muscle cell fate
    • 10.1083/jcb.141.3.805, 2132737, 9566978
    • Hirschi K, Rohovsky SA, D'Amore PA. PDGF, TGF-β and heterotypic cell-cell interactions mediate the recruitment and differentiation of 10T1/2 cells to a smooth muscle cell fate. J Cell Biol 1998, 141:805-814. 10.1083/jcb.141.3.805, 2132737, 9566978.
    • (1998) J Cell Biol , vol.141 , pp. 805-814
    • Hirschi, K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 32
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellström M, Kalén M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 1999, 126:3047-3055.
    • (1999) Development , vol.126 , pp. 3047-3055
    • Hellström, M.1    Kalén, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 33
    • 0001505189 scopus 로고
    • An activated form of transforming growth factor beta is produced by co-cultures of endothelial cells and pericytes
    • 10.1073/pnas.86.12.4544, 287307, 2734305
    • Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA. An activated form of transforming growth factor beta is produced by co-cultures of endothelial cells and pericytes. Proc Natl Acad Sci USA 1989, 86:4544-4548. 10.1073/pnas.86.12.4544, 287307, 2734305.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4544-4548
    • Antonelli-Orlidge, A.1    Saunders, K.B.2    Smith, S.R.3    D'Amore, P.A.4
  • 34
    • 0033058421 scopus 로고    scopus 로고
    • The effect of co-culture with human smooth muscle cells on the proliferation, the IL-1 beta secretion, the PDGF production and tube formation of human aortic endothelial cells
    • 10.1002/(SICI)1099-0844(199906)17:2<123::AID-CBF817>3.0.CO;2-3, 10377958
    • Asakawa H, Kobayashi T. The effect of co-culture with human smooth muscle cells on the proliferation, the IL-1 beta secretion, the PDGF production and tube formation of human aortic endothelial cells. Cell Biochem Funct 1999, 17:123-130. 10.1002/(SICI)1099-0844(199906)17:2<123::AID-CBF817>3.0.CO;2-3, 10377958.
    • (1999) Cell Biochem Funct , vol.17 , pp. 123-130
    • Asakawa, H.1    Kobayashi, T.2
  • 35
    • 0343292988 scopus 로고
    • Transforming growth factor-β increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability
    • 10.1073/pnas.85.4.1105, 279714, 3422482
    • Penttinen RP, Kobayashi S, Bornstein P. Transforming growth factor-β increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci USA 1988, 85:1105-1108. 10.1073/pnas.85.4.1105, 279714, 3422482.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1105-1108
    • Penttinen, R.P.1    Kobayashi, S.2    Bornstein, P.3
  • 36
    • 0026075910 scopus 로고
    • Production of transforming growth factor β1
    • 10.1172/JCI115393, 295478, 1832175
    • Majesky MW, Lindner V, Twardzik DR. Production of transforming growth factor β1. J Clin Invest 1991, 88:904-910. 10.1172/JCI115393, 295478, 1832175.
    • (1991) J Clin Invest , vol.88 , pp. 904-910
    • Majesky, M.W.1    Lindner, V.2    Twardzik, D.R.3
  • 38
    • 0026628265 scopus 로고
    • An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
    • 10.1056/NEJM199207093270202, 1603138
    • Christman BW, McPherson CD, Newman JH, King GA, Bernard GR, Groves BM, Loyd JE. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med 1992, 327:70-75. 10.1056/NEJM199207093270202, 1603138.
    • (1992) N Engl J Med , vol.327 , pp. 70-75
    • Christman, B.W.1    McPherson, C.D.2    Newman, J.H.3    King, G.A.4    Bernard, G.R.5    Groves, B.M.6    Loyd, J.E.7
  • 39
    • 0032527955 scopus 로고    scopus 로고
    • Role of vasoactive mediators in primary and secondary pulmonary hypertension
    • 10.1016/S0002-9149(98)00296-3, 9678304
    • Mikhail G, Chester AH, Gibbs SR, Borland JAA, Banner NR, Yacoub MH. Role of vasoactive mediators in primary and secondary pulmonary hypertension. Am J Cardiol 1998, 82:254-255. 10.1016/S0002-9149(98)00296-3, 9678304.
    • (1998) Am J Cardiol , vol.82 , pp. 254-255
    • Mikhail, G.1    Chester, A.H.2    Gibbs, S.R.3    Borland, J.A.A.4    Banner, N.R.5    Yacoub, M.H.6
  • 40
    • 0031671673 scopus 로고    scopus 로고
    • Elastase and the pathobiology of unexplained pulmonary hypertension
    • Rabinovitch M. Elastase and the pathobiology of unexplained pulmonary hypertension. Chest 1998, 114:213-224.
    • (1998) Chest , vol.114 , pp. 213-224
    • Rabinovitch, M.1
  • 41
    • 0032604835 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms responsible for the pathogenesis of primary pulmonary hypertension
    • 10.1002/(SICI)1099-0496(1999)27:18+<194::AID-PPUL63>3.0.CO;2-6, 10093141
    • Rubin LJ. Cellular and molecular mechanisms responsible for the pathogenesis of primary pulmonary hypertension. Pediatr Pulmonol Suppl 1999, 18:194-197. 10.1002/(SICI)1099-0496(1999)27:18+<194::AID-PPUL63>3.0.CO;2-6, 10093141.
    • (1999) Pediatr Pulmonol Suppl , vol.18 , pp. 194-197
    • Rubin, L.J.1
  • 42
    • 0000110162 scopus 로고
    • Primary pulmonary hypertension. A pathologic study of the lung vessels in 156 clinically diagnosed cases
    • Wagenvoort CA, Wagenvoort N. Primary pulmonary hypertension. A pathologic study of the lung vessels in 156 clinically diagnosed cases. Circulation 1970, 42:1163-1171.
    • (1970) Circulation , vol.42 , pp. 1163-1171
    • Wagenvoort, C.A.1    Wagenvoort, N.2
  • 43
    • 0029146280 scopus 로고
    • Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media
    • 10.1172/JCI118031, 185198, 7615796
    • Wohrley JD, Frid MG, Moiseeva EP, Orton EC, Belknap JK, Stenmark KR. Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media. J Clin Invest 1995, 96:273-281. 10.1172/JCI118031, 185198, 7615796.
    • (1995) J Clin Invest , vol.96 , pp. 273-281
    • Wohrley, J.D.1    Frid, M.G.2    Moiseeva, E.P.3    Orton, E.C.4    Belknap, J.K.5    Stenmark, K.R.6
  • 44
    • 0035101124 scopus 로고    scopus 로고
    • HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema
    • 1850338, 11238043
    • Golpon HA, Geraci MW, Moore MD, Miller HL, Miller GJ, Tuder RM, Voelkel NF. HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema. Am J Pathol 2001, 158:955-966. 1850338, 11238043.
    • (2001) Am J Pathol , vol.158 , pp. 955-966
    • Golpon, H.A.1    Geraci, M.W.2    Moore, M.D.3    Miller, H.L.4    Miller, G.J.5    Tuder, R.M.6    Voelkel, N.F.7
  • 47
    • 0031829977 scopus 로고    scopus 로고
    • Altered regulation of smooth muscle cell proliferation and apoptosis in small arteries of spontaneously hypertensive rats
    • Diez J, Fortuno M, Zalba G, Etayo J, Fortuno A, Ravassa S, Beaumont J. Altered regulation of smooth muscle cell proliferation and apoptosis in small arteries of spontaneously hypertensive rats. Eur Heart J 1998, 19:G29-G33.
    • (1998) Eur Heart J , vol.19
    • Diez, J.1    Fortuno, M.2    Zalba, G.3    Etayo, J.4    Fortuno, A.5    Ravassa, S.6    Beaumont, J.7
  • 48
    • 0032978142 scopus 로고    scopus 로고
    • The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
    • 10.1038/6585, 10086392
    • Guevara N, Kim H, Antonova E, Chan L. The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo. Nat Med 1999, 5:335-339. 10.1038/6585, 10086392.
    • (1999) Nat Med , vol.5 , pp. 335-339
    • Guevara, N.1    Kim, H.2    Antonova, E.3    Chan, L.4
  • 50
    • 0031931014 scopus 로고    scopus 로고
    • Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease
    • 10.1038/nm0298-222, 9461197
    • Pollman M, Hall J, Mann M, Zhang L, Gibbons G. Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease. Nat Med 1998, 4:222-227. 10.1038/nm0298-222, 9461197.
    • (1998) Nat Med , vol.4 , pp. 222-227
    • Pollman, M.1    Hall, J.2    Mann, M.3    Zhang, L.4    Gibbons, G.5
  • 51
    • 0032477728 scopus 로고    scopus 로고
    • Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response
    • 10.1073/pnas.95.3.1213, 18722, 9448311
    • Sata M, Perlman H, Muruve D, Silver M, Ikebe M, Libermann T, Oettgen P, Walsh K. Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response. Proc Natl Acad Sci USA 1998, 95:1213-1217. 10.1073/pnas.95.3.1213, 18722, 9448311.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1213-1217
    • Sata, M.1    Perlman, H.2    Muruve, D.3    Silver, M.4    Ikebe, M.5    Libermann, T.6    Oettgen, P.7    Walsh, K.8
  • 53
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • 10.1152/physrev.00041.2003, 15269336
    • Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004, 84:767-801. 10.1152/physrev.00041.2003, 15269336.
    • (2004) Physiol Rev , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 54
    • 0033588351 scopus 로고    scopus 로고
    • Evidence from a novel human cell clone that adult vascular smooth muscle cells can convert reversibly between noncontractile and contractile phenotypes
    • Li S, Sims S, Jiao Y, Chow LH, Pickering JG. Evidence from a novel human cell clone that adult vascular smooth muscle cells can convert reversibly between noncontractile and contractile phenotypes. Circ Res 1999, 85:338-348.
    • (1999) Circ Res , vol.85 , pp. 338-348
    • Li, S.1    Sims, S.2    Jiao, Y.3    Chow, L.H.4    Pickering, J.G.5
  • 55
    • 33748431371 scopus 로고    scopus 로고
    • Apoptosis of pulmonary microvascular endothelial cells stimulates vascular smooth muscle cell growth
    • 10.1152/ajplung.00111.2005, 16617095
    • Sakao S, Taraseviciene-Stewart L, Wood K, Cool CD, Voelkel NF. Apoptosis of pulmonary microvascular endothelial cells stimulates vascular smooth muscle cell growth. Am J Physiol Lung Cell Mol Physiol 2006, 291:L362-L368. 10.1152/ajplung.00111.2005, 16617095.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Sakao, S.1    Taraseviciene-Stewart, L.2    Wood, K.3    Cool, C.D.4    Voelkel, N.F.5
  • 56
    • 0023122142 scopus 로고
    • Neointimal hyperplasia occurring after carotid endarterectomy in a canine model: Effect of endothelial cell seeding vs perioperative aspirin
    • 10.1067/mva.1987.avs0050118, 3795378
    • Bush HJ, Jakubowski JA, Sentissi JM. Neointimal hyperplasia occurring after carotid endarterectomy in a canine model: Effect of endothelial cell seeding vs perioperative aspirin. J Vasc Surg 1987, 5:118-125. 10.1067/mva.1987.avs0050118, 3795378.
    • (1987) J Vasc Surg , vol.5 , pp. 118-125
    • Bush, H.J.1    Jakubowski, J.A.2    Sentissi, J.M.3
  • 57
    • 0011184262 scopus 로고    scopus 로고
    • Endothelial cell resurfacing improves remodeling of balloon-injured arteries in the hypercholesterolemic rabbit
    • Conte MS. Endothelial cell resurfacing improves remodeling of balloon-injured arteries in the hypercholesterolemic rabbit. Surg Forum 1996, 47:333-336.
    • (1996) Surg Forum , vol.47 , pp. 333-336
    • Conte, M.S.1
  • 58
    • 0035970616 scopus 로고    scopus 로고
    • Cellular pathology of atherosclerosis: smooth muscle cells prime cocultured endothelial cells for enhanced leukocyte adhesion
    • Rainger GE, Nash GB. Cellular pathology of atherosclerosis: smooth muscle cells prime cocultured endothelial cells for enhanced leukocyte adhesion. Circ Res 2001, 88:615-622.
    • (2001) Circ Res , vol.88 , pp. 615-622
    • Rainger, G.E.1    Nash, G.B.2
  • 59
    • 1842507562 scopus 로고    scopus 로고
    • Neointimal smooth muscle cells display a proinflammatory phenotype resulting in increased leukocyte recruitment mediated by P-selectin and chemokines
    • 10.1161/01.RES.0000121105.72718.5C, 14963004
    • Zeiffer U, Schober A, Lietz M, Liehn EA, Erl W, Emans N, Yan ZQ, Weber C. Neointimal smooth muscle cells display a proinflammatory phenotype resulting in increased leukocyte recruitment mediated by P-selectin and chemokines. Circ Res 2004, 94:776-784. 10.1161/01.RES.0000121105.72718.5C, 14963004.
    • (2004) Circ Res , vol.94 , pp. 776-784
    • Zeiffer, U.1    Schober, A.2    Lietz, M.3    Liehn, E.A.4    Erl, W.5    Emans, N.6    Yan, Z.Q.7    Weber, C.8
  • 60
    • 0036517883 scopus 로고    scopus 로고
    • How cells change their phenotype
    • 10.1038/nrm761, 11994739
    • Tosh D, Slack JM. How cells change their phenotype. Nature Reviews Molecular Cell Biology 2002, 3:187-194. 10.1038/nrm761, 11994739.
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , pp. 187-194
    • Tosh, D.1    Slack, J.M.2
  • 61
    • 0035824921 scopus 로고    scopus 로고
    • Contribution of adventitial fibroblasts to neointima formation and vascular remodeling
    • 10.1161/hh2401.100844, 11739275
    • Sartore S, Chiavegato A, Faggin E, Franch R, Puato M, Ausoni S, Pauletto P. Contribution of adventitial fibroblasts to neointima formation and vascular remodeling. Circ Res 2001, 89:1111-1121. 10.1161/hh2401.100844, 11739275.
    • (2001) Circ Res , vol.89 , pp. 1111-1121
    • Sartore, S.1    Chiavegato, A.2    Faggin, E.3    Franch, R.4    Puato, M.5    Ausoni, S.6    Pauletto, P.7
  • 62
    • 0000622113 scopus 로고
    • Modulation of vascular wall cell phenotype in pulmonary hypertension
    • Portland Press, London, UK, Bishop JE, Reeves JJ, Laurent GJ
    • Stenmark KR, Durmowicz AG, Dempsey EC. Modulation of vascular wall cell phenotype in pulmonary hypertension. Pulmonary Vascular Remodeling 1995, Portland Press, London, UK, Bishop JE, Reeves JJ, Laurent GJ.
    • (1995) Pulmonary Vascular Remodeling
    • Stenmark, K.R.1    Durmowicz, A.G.2    Dempsey, E.C.3
  • 63
    • 30144434832 scopus 로고    scopus 로고
    • The extracellular matrix microenvironment specifies pulmonary endothelial cell identity: roles of tenascin-C and RhoA
    • 10.1378/chest.128.6_suppl.564S, 16373827
    • Sisbarro L, Ihida-Stansbury K, Stevens T, Bauer N, McMurtry I, Jones PL. The extracellular matrix microenvironment specifies pulmonary endothelial cell identity: roles of tenascin-C and RhoA. Chest 2005, 128. 10.1378/chest.128.6_suppl.564S, 16373827.
    • (2005) Chest , vol.128
    • Sisbarro, L.1    Ihida-Stansbury, K.2    Stevens, T.3    Bauer, N.4    McMurtry, I.5    Jones, P.L.6
  • 64
    • 0030992961 scopus 로고    scopus 로고
    • An origin for smooth muscle cells from endothelium?
    • Majesky MW, Schwartz SM. An origin for smooth muscle cells from endothelium?. Circ Res 1997, 80:601-603.
    • (1997) Circ Res , vol.80 , pp. 601-603
    • Majesky, M.W.1    Schwartz, S.M.2
  • 65
    • 0030925749 scopus 로고    scopus 로고
    • Perspectives series: cell adhesion in vascular biology. Smooth muscle migration in atherosclerosis and restenosis
    • 10.1172/JCI119472, 508129, 9185501
    • Schwartz SM. Perspectives series: cell adhesion in vascular biology. Smooth muscle migration in atherosclerosis and restenosis. J Clin Invest 1997, 99:2814-2817. 10.1172/JCI119472, 508129, 9185501.
    • (1997) J Clin Invest , vol.99 , pp. 2814-2817
    • Schwartz, S.M.1
  • 66
    • 0033985945 scopus 로고    scopus 로고
    • Intimal thickening involves transdifferentiation of embryonic endothelial cells
    • 10.1002/(SICI)1097-0185(20000101)258:1<47::AID-AR6>3.0.CO;2-W, 10603448
    • Arciniegas E, Ponce L, Hartt Y, Graterol A, Carlini RG. Intimal thickening involves transdifferentiation of embryonic endothelial cells. Anat Rec 2000, 258:47-57. 10.1002/(SICI)1097-0185(20000101)258:1<47::AID-AR6>3.0.CO;2-W, 10603448.
    • (2000) Anat Rec , vol.258 , pp. 47-57
    • Arciniegas, E.1    Ponce, L.2    Hartt, Y.3    Graterol, A.4    Carlini, R.G.5
  • 68
    • 0031753080 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation
    • Okada K, Bernstein M, Zhang W, Schuster D, Botney M. Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation. Am J Respir Crit Care Med 1998, 158:939-950.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 939-950
    • Okada, K.1    Bernstein, M.2    Zhang, W.3    Schuster, D.4    Botney, M.5
  • 69
    • 0025803950 scopus 로고
    • Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture
    • Lee SL, Wang WW, Moore BJ, Fanburg BL. Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture. Circ Res 1991, 68:1362-1368.
    • (1991) Circ Res , vol.68 , pp. 1362-1368
    • Lee, S.L.1    Wang, W.W.2    Moore, B.J.3    Fanburg, B.L.4
  • 70
    • 35948949993 scopus 로고    scopus 로고
    • Transdifferentiation of endothelial cells in primary pulmonary hypertension
    • Cool CD, Wood K, Voelkel NF. Transdifferentiation of endothelial cells in primary pulmonary hypertension. Am J Resp Crit Care Med 2004, 167:A844.
    • (2004) Am J Resp Crit Care Med , vol.167
    • Cool, C.D.1    Wood, K.2    Voelkel, N.F.3
  • 71
    • 35948964028 scopus 로고    scopus 로고
    • VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells
    • 10.1096/fj.07-8432com, 17567571
    • Sakao S, Taraseviciene-Stewart L, Cool CD, Tada Y, Kasahara Y, Kurosu K, Tanabe N, Takiguchi Y, Tatsumi K, Kuriyama T, Voelkel NF. VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells. FASEB J 2007, 21:3640-3652. 10.1096/fj.07-8432com, 17567571.
    • (2007) FASEB J , vol.21 , pp. 3640-3652
    • Sakao, S.1    Taraseviciene-Stewart, L.2    Cool, C.D.3    Tada, Y.4    Kasahara, Y.5    Kurosu, K.6    Tanabe, N.7    Takiguchi, Y.8    Tatsumi, K.9    Kuriyama, T.10    Voelkel, N.F.11
  • 72
    • 0037076796 scopus 로고    scopus 로고
    • Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis
    • Frid MG, Kale VA, Stenmark KR. Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis. Circ Res 2002, 14:1189-1196.
    • (2002) Circ Res , vol.14 , pp. 1189-1196
    • Frid, M.G.1    Kale, V.A.2    Stenmark, K.R.3
  • 73
    • 0026453307 scopus 로고
    • Transforming growth factor beta 1 promotes the differentiation of endothelial cells into smooth muscle-like cells in vitro
    • Arciniegas E, Sutton AB, Allen TD, Schor AM. Transforming growth factor beta 1 promotes the differentiation of endothelial cells into smooth muscle-like cells in vitro. J Cell Sci 1992, 103:521-529.
    • (1992) J Cell Sci , vol.103 , pp. 521-529
    • Arciniegas, E.1    Sutton, A.B.2    Allen, T.D.3    Schor, A.M.4
  • 74
    • 0032847679 scopus 로고    scopus 로고
    • Similarities and differences in smooth muscle -actin induction by TGF-s in smooth muscle versus non-smooth muscle cells
    • Hautmann MB, Adam PJ, Owens GK. Similarities and differences in smooth muscle -actin induction by TGF-s in smooth muscle versus non-smooth muscle cells. Arterioscler Thromb Vasc Biol 1999, 19:2049-2058.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2049-2058
    • Hautmann, M.B.1    Adam, P.J.2    Owens, G.K.3
  • 75
    • 0015829488 scopus 로고
    • Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis
    • 10.1126/science.180.4093.1332, 4350926
    • Ross R, Glomset JA. Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 1973, 180:1332-1339. 10.1126/science.180.4093.1332, 4350926.
    • (1973) Science , vol.180 , pp. 1332-1339
    • Ross, R.1    Glomset, J.A.2
  • 76
    • 0036105149 scopus 로고    scopus 로고
    • Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis
    • 10.1038/nm0402-403, 11927948
    • Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, Hirai H, Makuuchi M, Hirata Y, Nagai R. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002, 8:403-409. 10.1038/nm0402-403, 11927948.
    • (2002) Nat Med , vol.8 , pp. 403-409
    • Sata, M.1    Saiura, A.2    Kunisato, A.3    Tojo, A.4    Okada, S.5    Tokuhisa, T.6    Hirai, H.7    Makuuchi, M.8    Hirata, Y.9    Nagai, R.10
  • 77
    • 0034948743 scopus 로고    scopus 로고
    • Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy
    • 10.1038/89121, 11385513
    • Shimizu K, Sugiyama S, Aikawa M, Fukumoto Y, Rabkin E, Libby P, Mitchell RN. Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy. Nat Med 2001, 7:738-741. 10.1038/89121, 11385513.
    • (2001) Nat Med , vol.7 , pp. 738-741
    • Shimizu, K.1    Sugiyama, S.2    Aikawa, M.3    Fukumoto, Y.4    Rabkin, E.5    Libby, P.6    Mitchell, R.N.7
  • 78
    • 0036645391 scopus 로고    scopus 로고
    • Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts
    • 10.1161/01.CIR.0000021923.58307.8F, 12093763
    • Glaser R, Lu MM, Narula N, Epstein JA. Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts. Circulation 2002, 106:17-19. 10.1161/01.CIR.0000021923.58307.8F, 12093763.
    • (2002) Circulation , vol.106 , pp. 17-19
    • Glaser, R.1    Lu, M.M.2    Narula, N.3    Epstein, J.A.4
  • 79
    • 0037015286 scopus 로고    scopus 로고
    • Smooth muscle progenitor cells in human blood
    • 10.1161/01.CIR.0000031525.61826.A8, 12208793
    • Simper D, Stalboerger PG, Panetta CJ, Wang S, Caplice NM. Smooth muscle progenitor cells in human blood. Circulation 2002, 106:1199-1204. 10.1161/01.CIR.0000031525.61826.A8, 12208793.
    • (2002) Circulation , vol.106 , pp. 1199-1204
    • Simper, D.1    Stalboerger, P.G.2    Panetta, C.J.3    Wang, S.4    Caplice, N.M.5
  • 80
    • 0036787541 scopus 로고    scopus 로고
    • Mooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells
    • Hu Y, Davison F, Ludewig B, Erdel M, Mayr M, Url M, Dietrich H, Xu Q. mooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells. Circulation 2002, 106:S1834-1839.
    • (2002) Circulation , vol.106
    • Hu, Y.1    Davison, F.2    Ludewig, B.3    Erdel, M.4    Mayr, M.5    Url, M.6    Dietrich, H.7    Xu, Q.8
  • 81
    • 0037019942 scopus 로고    scopus 로고
    • Both donor and recipient origins of smooth muscle cells in vein graft atherosclerotic lesions
    • 10.1161/01.RES.0000037090.34760.EE, 12364395
    • Hu Y, Mayr M, Metzler B, Erdel M, Davison F, Xu Q. Both donor and recipient origins of smooth muscle cells in vein graft atherosclerotic lesions. Circ Res 2002, 91:e13-e20. 10.1161/01.RES.0000037090.34760.EE, 12364395.
    • (2002) Circ Res , vol.91
    • Hu, Y.1    Mayr, M.2    Metzler, B.3    Erdel, M.4    Davison, F.5    Xu, Q.6
  • 82
    • 85047694430 scopus 로고    scopus 로고
    • Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice
    • 398426, 15124016
    • Hu Y, Zhang Z, Torsney E, Afzal AR, Davison F, Metzler B, Xu Q. Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. J Clin Invest 2004, 113:1258-1265. 398426, 15124016.
    • (2004) J Clin Invest , vol.113 , pp. 1258-1265
    • Hu, Y.1    Zhang, Z.2    Torsney, E.3    Afzal, A.R.4    Davison, F.5    Metzler, B.6    Xu, Q.7
  • 84
    • 34249340845 scopus 로고    scopus 로고
    • BMP induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK
    • 10.1016/j.cellsig.2007.01.017, 17317101
    • Beck SE, Jung BH, Del Rosario E, Gomez J, Carethers JM. BMP induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK. Cell Signal 2007, 19:1465-1472. 10.1016/j.cellsig.2007.01.017, 17317101.
    • (2007) Cell Signal , vol.19 , pp. 1465-1472
    • Beck, S.E.1    Jung, B.H.2    Del Rosario, E.3    Gomez, J.4    Carethers, J.M.5
  • 85
    • 34748837360 scopus 로고    scopus 로고
    • Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis
    • 10.1007/s12015-007-0006-6, 17873379
    • Katoh M. Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev 2007, 3:30-38. 10.1007/s12015-007-0006-6, 17873379.
    • (2007) Stem Cell Rev , vol.3 , pp. 30-38
    • Katoh, M.1
  • 86
    • 34547580553 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their receptor signaling in prostate cancer
    • Ye L, Lewis-Russell JM, Kyanaston HG, Jiang WG. Bone morphogenetic proteins and their receptor signaling in prostate cancer. Histol Histopathol 2007, 22:1129-1147.
    • (2007) Histol Histopathol , vol.22 , pp. 1129-1147
    • Ye, L.1    Lewis-Russell, J.M.2    Kyanaston, H.G.3    Jiang, W.G.4
  • 87
    • 34548387492 scopus 로고    scopus 로고
    • The hyperproliferative endothelial cell phenotype in idiopathic pulmonary arterial hypertension
    • 10.1152/ajplung.00246.2007, 17601794
    • Stevens T, Gillespie MN. The hyperproliferative endothelial cell phenotype in idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol 2007, 293:L546-L547. 10.1152/ajplung.00246.2007, 17601794.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Stevens, T.1    Gillespie, M.N.2
  • 88
    • 33847032960 scopus 로고    scopus 로고
    • The mammalian epigenome
    • 10.1016/j.cell.2007.01.033, 17320505
    • Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell 2007, 128:669-861. 10.1016/j.cell.2007.01.033, 17320505.
    • (2007) Cell , vol.128 , pp. 669-861
    • Bernstein, B.E.1    Meissner, A.2    Lander, E.S.3
  • 89
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: a landscape takes shape
    • 10.1016/j.cell.2007.02.006, 17320500
    • Goldberg AD, Allis CD, Bernstein E. Epigenetics: a landscape takes shape. Cell 2007, 128:635-638. 10.1016/j.cell.2007.02.006, 17320500.
    • (2007) Cell , vol.128 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 90
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • 10.1126/science.1086887, 12907790
    • Grewal SI, Moazed D. Heterochromatin and epigenetic control of gene expression. Science 2003, 301:798-802. 10.1126/science.1086887, 12907790.
    • (2003) Science , vol.301 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 91
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • 10.1016/j.cell.2007.01.030, 17320509
    • Groth A, Rocha W, Verreault A, Almouzni G. Chromatin challenges during DNA replication and repair. Cell 2007, 128:721-733. 10.1016/j.cell.2007.01.030, 17320509.
    • (2007) Cell , vol.128 , pp. 721-733
    • Groth, A.1    Rocha, W.2    Verreault, A.3    Almouzni, G.4
  • 92
    • 33646731984 scopus 로고    scopus 로고
    • Severe pulmonary hypertension in postmenopausal obese women
    • Taraseviciute A, Voelkel NF. Severe pulmonary hypertension in postmenopausal obese women. Eur J Med Res 2006, 11:198-202.
    • (2006) Eur J Med Res , vol.11 , pp. 198-202
    • Taraseviciute, A.1    Voelkel, N.F.2
  • 93
    • 0032822978 scopus 로고    scopus 로고
    • Hormone replacement therapy: a possible risk factor in carriers of familial primary pulmonary hypertension
    • 10.1378/chest.116.3.847, 10492306
    • Morse JH, Horn EM, Barst RJ. Hormone replacement therapy: a possible risk factor in carriers of familial primary pulmonary hypertension. Chest 1999, 116:847. 10.1378/chest.116.3.847, 10492306.
    • (1999) Chest , vol.116 , pp. 847
    • Morse, J.H.1    Horn, E.M.2    Barst, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.