Changes in pulmonary blood flow distribution in monocrotaline compared with hypoxia-induced models of pulmonary hypertension: Assessed using synchrotron radiation

Journal of Hypertension

Volumn 27, Issue 7, 2009, Pages 1410-1419

  Schwenke, Daryl O ^a   Pearson, James T ^b   Shimochi, Akito ^c   Kangawa, Kenji ^c   Tsuchimochi, Hirotsugu ^c   Umetani, Keiji ^d   Shirai, Mikiyasu ^e   Cragg, Patricia A ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b MONASH UNIVERSITY   (Australia)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

^e HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

Hypoxia; Monocrotaline; Pulmonary microvessels; Rat; Synchrotron radiation microangiography

Indexed keywords

BETA ADRENERGIC RECEPTOR; MONOCROTALINE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; DRUG ACTIVITY; HEART RATE; HEART RIGHT VENTRICLE PRESSURE; HYPOXIA; IMAGE ANALYSIS; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; LUNG BLOOD VESSEL; LUNG VASOCONSTRICTION; MALE; MEAN ARTERIAL PRESSURE; MICROANGIOGRAPHY; MICROANGIOPATHY; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; RECEPTOR BLOCKING; SYNCHROTRON RADIATION;

EID: 67649821764     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e32832af6a1     Document Type: Article

References (41)

1. Klinger JR, Hill NS. Right ventricular dysfunction in chronic obstructive pulmonary disease. Evaluation and management. Chest 1991; 99:715- 723.
2. Horstman DJ, Frank DU, Rich GF. Prolonged inhaled NO attenuates hypoxic, but not monocrotaline-induced, pulmonary vascular remodeling in rats. Anesth Analg 1998; 86:74-81.
3. Raoul W, Wagner-Ballon O, Saber G, Hulin A, Marcos E, Giraudier S, et al.Effects of bone marrow-derived cells on monocrotaline- and hypoxiainduced pulmonary hypertension in mice. Respir Res 2007; 8:8.
4. van Suylen RJ, Smits JF, Daemen MJ. Pulmonary artery remodeling differs in hypoxia- and monocrotaline-induced pulmonary hypertension. Am J Resp Crit Care Med 1998; 157:1423-1428.
5. Crossno JT Jr, Garat CV, Reusch JE, Morris KG, Dempsey EC, McMurtry IF, et al. Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodelling. Am J Physiol (Lung Cell Mol Physiol) 2007; 292:L885- 897.
6. Meyrick B, Gamble W, Reid L. Development of Crotalaria pulmonary hypertension: hemodynamic and structural study. Am J Physiol 1980; 239:H692-H702.
7. Schwenke DO, Pearson JT, Kangawa K, Umetani K, Shirai M. Changes in macrovessel pulmonary blood flow distribution following chronic hypoxia: assessed using synchrotron radiation microangiography. J Appl Physiol2008; 104:88-96.
8. Schwenke DO, Pearson JT, Kangawa K, Umetani K, Shirai M. Imaging of the pulmonary circulation in the closed-chest rat using synchrotron radiation microangiography. J Appl Physiol 2007; 102:787-793.
9. Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research 'Work in progress'. Circulation 2000; 102:2781- 2791.
10. Barbera JA, Peinado VI, Santos S. Pulmonary hypertension in COPD: old and new concepts. Monaldi Arch Chest Dis 2000; 55:445-449.
11. Voelkel NF, Tuder RM. Hypoxia-induced pulmonary vascular remodeling: a model for what human disease? J Clin Invest 2000; 106:733-738.
12. Laudi S, Steudel W, Jonscher K, Schoning W, Schniedewind B, Kaisers U, et al. Comparison of lung proteome profiles in two rodent models of pulmonary arterial hypertension. Proteomics 2007; 7:2469-2478.
13. Schwenke DO, Tokudome T, Shirai M, Hosoda H, Horio T, Kishimoto I, Kangawa K. Exogenous ghrelin attenuates the progression of chronic hypoxia-induced pulmonary hypertension in conscious rats. Endocrinology2008; 149:237-244.
14. Yang X, Chen W, Li F. The change and distribution of endothelin-1 in lung of hypoxic pulmonary hypertension rat. Hua Xi Yi Ke Da Xue Xue Bao 2000; 31:30-33.
15. Blumberg FC, Lorenz C, Wolf K, Sandner P, Riegger GA, Pfeifer M. Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension. Cardiovasc Res 2002; 55:171-177.
16. Frasch HF, Marshall C, Marshall BE. Endothelin-1 is elevated in monocrotalinepulmonary hypertension.AmJPhysiol1999;276:L304-310.
17. Mathew R, Zeballos GA, Tun H, Gewitz MH. Role of nitric oxide and endothelin-1 in monocrotaline-induced pulmonary hypertension in rats. Cardiovasc Res 1995; 30:739-746.
18. Mathew R, Gloster ES, Sundararajan T, Thompson CI, Zeballos GA, Gewitz MH. Role of inhibition of nitric oxide production in monocrotaline-induced pulmonary hypertension. J Appl Physiol 1997; 82:1493-1498.
19. Xue C, Rengasamy A, Le Cras TD, Koberna PA, Dailey GC, Johns RA. Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation of NOS by chronic hypoxia. Am J Physiol (Lung Cell Mol Physiol) 1994; 267:L667-L678.
20. Shirai M, Pearson JT, Shimouchi A, Nagaya N, Tsuchimochi H, Ninomiya I, Mori H. Changes in functional and histological distributions of nitric oxide synthase caused by chronic hypoxia in rat small pulmonary arteries. Br J Pharmacol 2003; 139:899-910.
21. Le Cras TD, Xue C, Rengasamy A, Johns RA. Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung. Am J Physiol (Lung Cell Mol Physiol) 1996; 270:L164-170.
22. Sato K, Rodman DM, McMurtry IF. Hypoxia inhibits increased ETB receptormediated NO synthesis in hypertensive rat lungs. Am J Physiol (Lung Cell Mol Physiol) 1999; 276:L571-L581.
23. Maruyama J, Maruyama K. Impaired nitric oxide-dependent responses and their recovery in hypertensive pulmonary arteries of rats. Am J Physiol1994; 266:H2476-H2488.
24. Crawley DE, Zhao L,Giembycz MA, Liu S, Barnes PJ, Winter RJ, Evans TW. Chronic hypoxia impairs soluble guanylyl cyclase-mediated pulmonary arterial relaxation in the rat. Am J Physiol 1992; 263:L325-L332.
25. Murata T, Yamawaki H, Hori M, Sato K, Ozaki H, Karaki H. Hypoxia impairs endothelium-dependent relaxation in organ cultured pulmonary artery. Eur J Pharmacol 2001; 421:45-53.
26. Hislop A, Reid L. New findings in pulmonary arteries of rats with hypoxiainduced pulmonary hypertension. Br J Exp Pathol 1976; 57:542-554.
27. Yamashita T, Kawashima S, Ozaki M, Namiki M, Shinohara M, Inoue N, et al.In vivo angiographic detection of vascular lesions in apolipoprotein Eknockout mice using a synchrotron radiation microangiography system. Circ J 2002; 66:1057-1059.
28. Fried R, Reid LM. Early recovery from hypoxic pulmonary hypertension: a structural and functional study. J Appl Physiol 1984; 57:1247-1253.
29. Hislop A, Reid L. Normal structure and dimensions of the pulmonary arteries in the rat. J Anat 1978; 125:71-83.
30. Meyrick B, Reid L. The effect of continued hypoxia on rat pulmonary arterial circulation. An ultrastructural study. Lab Invest 1978; 38:188-200.
31. Sasaki S, Kobayashi N, Dambara T, Kira S, Sakai T. Structural organization of pulmonary arteries in the rat lung. Anat Embryol (Berl) 1995; 191:477- 489.
32. Nagaoka T, Fagan KA, Gebb SA, Morris KG, Suzuki T, Shimokawa H, et al.Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am J Resp Crit Care Med 2005; 171:494-499.
33. RabinovitchM, Gamble W, Nadas AS, MiettinenOS, Reid L. Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features. Am J Physiol 1979; 236:H818-827.
34. Moudgil R, Michelakis ED, Archer SL. Hypoxic pulmonary vasoconstriction. J Appl Physiol 2005; 98:390-403.
35. Shirai M, Matsukawa K, Nishiura N, Kawaguchi AT, Ninomiya I. Changes in efferent pulmonary sympathetic nerve activity during systemic hypoxia in anesthetized cats. Am J Physiol (Regul Integr Comp Physiol) 1995; 269:R1404-1409.
36. Shirai M, Shindo T, Ninomiya I. Beta-adrenergic mechanisms attenuated hypoxic pulmonary vasoconstriction during systemic hypoxia in cats. Am J Physiol (Heart Circ Physiol) 1994; 266:H1777-1785.
37. Birnkrant DJ, Davis PB, Ernsberger P. Visualization of high- and low-affinity beta-adrenergic receptors in rat lung: upregulation by chronic hypoxia. Am J Physiol 1993; 265:L389-394.
38. Winter RJ, Dickinson KE, Rudd RM, Sever PS. Tissue specific modulation of beta-adrenoceptor number in rats with chronic hypoxia with an attenuated response to down-regulation by salbutamol. Clin Sci (Lond)1986; 70:159-165.
39. Brown L, Miller J, Dagger A, Sernia C. Cardiac and vascular responses after monocrotaline-induced hypertrophy in rats. J Cardiol Pharmacol 1998; 31:108-115.
40. Tucker A, Bryant SE, Frost HH, Migally N. Chemical sympathectomy and serotonin inhibition reduce monocrotaline-induced right ventricular hypertrophy in rats. Can J Physiol Pharmacol 1983; 61:356-362.
41. Yamada Y, Okumura K, Hashimoto H, Ito T, Satake T. Altered myocardial acetylcholine and norepinephrine concentrations in right ventricular hypertrophy and failure. Heart Vessels 1991; 6:150-157.