-
1
-
-
0030699366
-
Interleukin-11: Biological activity and clinical studies
-
DORNER, A. J., S. J. GOLDMAN & J. C. J. KEITH. 1997. Interleukin-11: Biological activity and clinical studies. BioDrugs 6: 418-429.
-
(1997)
BioDrugs
, vol.6
, pp. 418-429
-
-
Dorner, A.J.1
Goldman, S.J.2
Keith, J.C.J.3
-
2
-
-
0030917254
-
Interleukin-11: Review of molecular, cell biology, and clinical use
-
DU, X. & D. A. WILLIAMS. 1997. Interleukin-11: Review of molecular, cell biology, and clinical use. Blood 89: 3897-3908.
-
(1997)
Blood
, vol.89
, pp. 3897-3908
-
-
Du, X.1
Williams, D.A.2
-
3
-
-
0030014438
-
Clinical development of recombinant human interleukin-11 to treat chemotherapy-induced thrombocytopenia
-
KAYE, J. A. 1996. Clinical development of recombinant human interleukin-11 to treat chemotherapy-induced thrombocytopenia. Curr. Opin. Hematol. 3: 209-215.
-
(1996)
Curr. Opin. Hematol.
, vol.3
, pp. 209-215
-
-
Kaye, J.A.1
-
4
-
-
0025841744
-
Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6
-
BAUMANN, H. & P. SCHENDEL. 1991. Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6. J. Biol. Chem. 266: 20424-20427.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20424-20427
-
-
Baumann, H.1
Schendel, P.2
-
5
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
TAGA, T. & T. KISHIMOTO. 1997. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15: 797-819.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
6
-
-
15844395460
-
A phase I trial of recombinant human interleukin-11 (neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy
-
GORDON, M. S., W. J. MCCASKILL-STEVENS, L. A. BATTIATO, J. LOEWY, D. LOESCH, E. BREEDEN, R. HOFFMAN, K. J. BEACH, B. KUCA, J. KAYE & G. W. SLEDGE, JR. 1996. A phase I trial of recombinant human interleukin-11 (neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy. Blood 87: 3615-3624.
-
(1996)
Blood
, vol.87
, pp. 3615-3624
-
-
Gordon, M.S.1
Mccaskill-Stevens, W.J.2
Battiato, L.A.3
Loewy, J.4
Loesch, D.5
Breeden, E.6
Hoffman, R.7
Beach, K.J.8
Kuca, B.9
Kaye, J.10
Sledge Jr., G.W.11
-
7
-
-
8944261227
-
Concurrent IL-6 + G-CSF to support dose-intensified cyclophosphamide/doxorubicin (CD): Possible acceleration of hematologic recovery from chemotherapy-induced thrombocytopenia
-
DEMITRI, G. D., D. F. HAYES, E. A. MERICA, B. CAP & J. SPARANO. 1994. Concurrent IL-6 + G-CSF to support dose-intensified cyclophosphamide/doxorubicin (CD): Possible acceleration of hematologic recovery from chemotherapy-induced thrombocytopenia. Blood 84: 29a.
-
(1994)
Blood
, vol.84
-
-
Demitri, G.D.1
Hayes, D.F.2
Merica, E.A.3
Cap, B.4
Sparano, J.5
-
8
-
-
0030587817
-
Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production
-
TREPICCHIO, W. L., M. BOZZA, G. PEDNEAULT & A. J. DORNER. 1996. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 157: 3627-3634.
-
(1996)
J. Immunol.
, vol.157
, pp. 3627-3634
-
-
Trepicchio, W.L.1
Bozza, M.2
Pedneault, G.3
Dorner, A.J.4
-
9
-
-
0030586606
-
IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury
-
REDLICH, C. A., X. GAO, S. ROCKWELL, M. KELLEY & J. A. ELIAS. 1996. IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury. J. Immunol. 157: 1705-1710.
-
(1996)
J. Immunol.
, vol.157
, pp. 1705-1710
-
-
Redlich, C.A.1
Gao, X.2
Rockwell, S.3
Kelley, M.4
Elias, J.A.5
-
10
-
-
0031298532
-
IL-11 regulates macrophage effector function through the inhibition of Nuclear Factor-κB
-
TREPICCHIO, W. L., L. WANG, M. BOZZA & A. J. DORNER. 1997. IL-11 regulates macrophage effector function through the inhibition of Nuclear Factor-κB. J. Immunol. 159: 5661-5670.
-
(1997)
J. Immunol.
, vol.159
, pp. 5661-5670
-
-
Trepicchio, W.L.1
Wang, L.2
Bozza, M.3
Dorner, A.J.4
-
11
-
-
0028281794
-
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
-
STAHL, N., T. G. BOULTON, T. FARRUGGELLA, N. Y. IP, S. DAVIS, B. A. WITTHUHN, F. W. QUELLE, O. SILVENNOINEN, G. BARBIERI, S. PELLEGRINI et al. 1994. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. Science 263: 92-95.
-
(1994)
Science
, vol.263
, pp. 92-95
-
-
Stahl, N.1
Boulton, T.G.2
Farruggella, T.3
Ip, N.Y.4
Davis, S.5
Witthuhn, B.A.6
Quelle, F.W.7
Silvennoinen, O.8
Barbieri, G.9
Pellegrini, S.10
-
12
-
-
0028921573
-
Jaks and Stats in signaling by the cytokine receptor superfamily
-
IHLE, J. N. & I. M. KERR. 1995. Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet. 11: 69-74.
-
(1995)
Trends Genet.
, vol.11
, pp. 69-74
-
-
Ihle, J.N.1
Kerr, I.M.2
-
13
-
-
0031229726
-
Interleukin-11 inhibits macrophage interleukin-12 production
-
LENG, S. X. & J. A. ELIAS. 1997. Interleukin-11 inhibits macrophage interleukin-12 production. J. Immunol. 159: 2161-2168.
-
(1997)
J. Immunol.
, vol.159
, pp. 2161-2168
-
-
Leng, S.X.1
Elias, J.A.2
-
14
-
-
0029983730
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
-
BEYAERT, R., A. CUENDA, W. VANDEN BERGHE, S. PLAISANCE, J. C. LEE, G. HAEGEMAN, P. COHEN & W. FIERS. 1996. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. Embo. J. 15: 1914-1923.
-
(1996)
Embo. J.
, vol.15
, pp. 1914-1923
-
-
Beyaert, R.1
Cuenda, A.2
Vanden Berghe, W.3
Plaisance, S.4
Lee, J.C.5
Haegeman, G.6
Cohen, P.7
Fiers, W.8
-
15
-
-
0031008005
-
Mast cell tumor necrosis factor alpha production is regulated by MEK kinases
-
ISHIZUKA, T., N. TERADA, P. GERWINS, E. HAMELMANN, A. OSHIBA, G. R. FANGER, G. L. JOHNSON & E. W. GELFAND. 1997. Mast cell tumor necrosis factor alpha production is regulated by MEK kinases. Proc. Natl. Acad. Sci. USA 94: 6358-6363.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6358-6363
-
-
Ishizuka, T.1
Terada, N.2
Gerwins, P.3
Hamelmann, E.4
Oshiba, A.5
Fanger, G.R.6
Johnson, G.L.7
Gelfand, E.W.8
-
16
-
-
0030977398
-
Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases
-
ZHANG, C., R. A. BAUMGARTNER, K. YAMADA & M. A. BEAVEN. 1997. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. J. Biol. Chem. 272: 13397-13402.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13397-13402
-
-
Zhang, C.1
Baumgartner, R.A.2
Yamada, K.3
Beaven, M.A.4
-
17
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
RAINGEAUD, J., S. GUPTA, J. S. ROGERS, M. DICKENS, J. HAN, R. J. ULEVITCH & R. J. DAVIS. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270: 7420-7426.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
18
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
LEE, J. C., J. T. LAYDON, P. C. MCDONNELL, T. F. GALLAGHER, S. KUMAR, D. GREEN, D. MCNULTY, M. J. BLUMENTHAL, J. R. HEYS, S. W. LANDVATTER et al. 1994. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372: 739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
Mcdonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
Mcnulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
19
-
-
0026061740
-
Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture
-
MUSASHI, M., Y. C. YANG, S. R. PAUL, S. C. CLARK, T. SUDO & M. OGAWA. 1991. Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture. Proc. Natl. Acad. Sci. USA 88: 765-769.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 765-769
-
-
Musashi, M.1
Yang, Y.C.2
Paul, S.R.3
Clark, S.C.4
Sudo, T.5
Ogawa, M.6
-
20
-
-
0026755568
-
Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture
-
TSUJI, K., S. D. LYMAN, T. SUDO, S. C. CLARK, & M. OGAWA. 1992. Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79: 2855-2860.
-
(1992)
Blood
, vol.79
, pp. 2855-2860
-
-
Tsuji, K.1
Lyman, S.D.2
Sudo, T.3
Clark, S.C.4
Ogawa, M.5
-
21
-
-
0025942679
-
Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice
-
MUSASHI, M., S. C. CLARK, T. SUDO, D. L. URDAL & M. OGAWA. 1991. Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice. Blood 78: 1448-1451.
-
(1991)
Blood
, vol.78
, pp. 1448-1451
-
-
Musashi, M.1
Clark, S.C.2
Sudo, T.3
Urdal, D.L.4
Ogawa, M.5
-
22
-
-
0027516460
-
Protective role of interleukin 6 in the lipopolysaccharide-galactosamine septic shock model
-
BARTON, B. E. & J. V. JACKSON. 1993. Protective role of interleukin 6 in the lipopolysaccharide-galactosamine septic shock model. Infect. Immun. 61: 1496-1499.
-
(1993)
Infect. Immun.
, vol.61
, pp. 1496-1499
-
-
Barton, B.E.1
Jackson, J.V.2
-
23
-
-
0030044284
-
Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin induced toxic shock model
-
BARTON, B. E., J. SHORTALL & J. V. JACKSON. 1996. Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin induced toxic shock model. Infect. Immun. 64: 714-718.
-
(1996)
Infect. Immun.
, vol.64
, pp. 714-718
-
-
Barton, B.E.1
Shortall, J.2
Jackson, J.V.3
-
24
-
-
15844429135
-
The role of gp130-mediated signals in osteoclast development: Regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures
-
ROMAS, E., N. UDAGAWA, H. ZHOU, T. TAMURA, M. SAITO, T. TAGA, D. J. HILTON, T. SUDA, K. W. NG & T. J. MARTIN. 1996. The role of gp130-mediated signals in osteoclast development: Regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures. J. Exp. Med. 183: 2581-2591.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2581-2591
-
-
Romas, E.1
Udagawa, N.2
Zhou, H.3
Tamura, T.4
Saito, M.5
Taga, T.6
Hilton, D.J.7
Suda, T.8
Ng, K.W.9
Martin, T.J.10
-
25
-
-
0028281827
-
Interleukin-11: A new cytokine critical for osteoclast development
-
GIRASOLE, G., G. PASSERI, R. L. JILKA & S. C. MANOLAGAS. 1994. Interleukin-11: A new cytokine critical for osteoclast development. J. Clin. Invest. 93: 1516-1524.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1516-1524
-
-
Girasole, G.1
Passeri, G.2
Jilka, R.L.3
Manolagas, S.C.4
-
26
-
-
0028075945
-
Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction
-
HILTON, D. J., A. A. HILTON, A. RAICEVIC, S. RAKAR, M. HARRISON-SMITH, N. M. GOUGH, C. G. BEGLEY, D. METCALF, N. A. NICOLA & T. A. WILLSON. 1994. Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction. Embo. J. 13: 4765-4775.
-
(1994)
Embo. J.
, vol.13
, pp. 4765-4775
-
-
Hilton, D.J.1
Hilton, A.A.2
Raicevic, A.3
Rakar, S.4
Harrison-Smith, M.5
Gough, N.M.6
Begley, C.G.7
Metcalf, D.8
Nicola, N.A.9
Willson, T.A.10
-
27
-
-
0030956567
-
Expression of murine interleukin 11 and its receptor alpha-chain in adult and embryonic tissues
-
DAVIDSON, A. J., S. A. FREEMAN, K. E. CROSIER, C. R. WOOD & P. S. CROSIER. 1997. Expression of murine interleukin 11 and its receptor alpha-chain in adult and embryonic tissues. Stem Cells 15: 119-124.
-
(1997)
Stem Cells
, vol.15
, pp. 119-124
-
-
Davidson, A.J.1
Freeman, S.A.2
Crosier, K.E.3
Wood, C.R.4
Crosier, P.S.5
-
28
-
-
17944387585
-
Identification of a second murine interleukin-11 receptor alpha-chain gene (IL11Ra2) with a restricted pattern of expression
-
ROBB, L., D. J. HILTON, P. T. BROOK-CARTER & C. G. BEGLEY. 1997. Identification of a second murine interleukin-11 receptor alpha-chain gene (IL11Ra2) with a restricted pattern of expression. Genomics 40: 387-394.
-
(1997)
Genomics
, vol.40
, pp. 387-394
-
-
Robb, L.1
Hilton, D.J.2
Brook-Carter, P.T.3
Begley, C.G.4
-
29
-
-
0028064835
-
High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130
-
WARD, L. D., G. J. HOWLETT, G. DISCOLO, K. YASUKAWA, A. HAMMACHER, R. L. MORITZ & R. J. SIMPSON. 1994. High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130. J. Biol. Chem. 269: 23286-23289.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23286-23289
-
-
Ward, L.D.1
Howlett, G.J.2
Discolo, G.3
Yasukawa, K.4
Hammacher, A.5
Moritz, R.L.6
Simpson, R.J.7
-
30
-
-
0029002866
-
Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling
-
PAONESSA, G., R. GRAZIANI, A. DE SERIO, R. SAVINO, L. CIAPPONI, A. LAHM, A. L. SALVATI, C. TONIATTI & G. CILIBERTO. 1995. Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling. Embo. J. 14: 1942-1951.
-
(1995)
Embo. J.
, vol.14
, pp. 1942-1951
-
-
Paonessa, G.1
Graziani, R.2
De Serio, A.3
Savino, R.4
Ciapponi, L.5
Lahm, A.6
Salvati, A.L.7
Toniatti, C.8
Ciliberto, G.9
-
31
-
-
0029849220
-
Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130
-
NEDDERMANN, P., R. GRAZIANI, G. CILIBERTO & G. PAONESSA. 1996. Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130. J. Biol. Chem. 271: 30986-30991.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30986-30991
-
-
Neddermann, P.1
Graziani, R.2
Ciliberto, G.3
Paonessa, G.4
|