메뉴 건너뛰기




Volumn 9, Issue 4, 2011, Pages 390-402

Atypical protein kinase Ci (PKCi) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to anoikis via PKCi-SKP2-AKT Pathway

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; PHOSPHATIDYLINOSITOL 3 KINASE; POLYUBIQUITIN; PROTEASOME; PROTEIN KINASE B; PROTEIN KINASE C IOTA; S PHASE KINASE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA; UBIQUITIN;

EID: 79954567234     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-10-0359     Document Type: Article
Times cited : (35)

References (37)
  • 1
    • 0033509879 scopus 로고    scopus 로고
    • Transhiatal esophagectomy: Clinical experience and refinements
    • discussion 400-3
    • Orringer MB, Marshall B, Iannettoni MD. Transhiatal esophagectomy: clinical experience and refinements. Ann Surg 1999;230:392-400; discussion 400-3.
    • (1999) Ann Surg , vol.230 , pp. 392-400
    • Orringer, M.B.1    Marshall, B.2    Iannettoni, M.D.3
  • 2
    • 2542506202 scopus 로고    scopus 로고
    • Protein kinase c (PKC) βII induces cell invasion through a Ras/Mek-, PKCι/Rac 1-dependent signaling pathway
    • DOI 10.1074/jbc.M400774200
    • Zhang J, Anastasiadis PZ, Liu Y, Thompson EA, Fields AP. Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway. J Biol Chem 2004; 279:22118-23. (Pubitemid 38679404)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.21 , pp. 22118-22123
    • Zhang, J.1    Anastasiadis, P.Z.2    Liu, Y.3    Thompson, E.A.4    Fields, A.P.5
  • 3
    • 36749037936 scopus 로고    scopus 로고
    • Targeting the oncogenic protein kinase Cι signalling pathway for the treatment of cancer
    • DOI 10.1042/BST0350996
    • Fields AP, Frederick LA, Regala RP. Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer. Biochem Soc Trans 2007;35:996-1000. (Pubitemid 350206412)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 996-1000
    • Fields, A.P.1    Frederick, L.A.2    Regala, R.P.3
  • 4
    • 0032566691 scopus 로고    scopus 로고
    • Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
    • DOI 10.1126/science.281.5385.2042
    • Le Good JA, Ziegler WH, Parekh DB, Alessi DR, Cohen P, Parker PJ. Protein kinase C isotypes controlled by phosphoinositide 3- kinase through the protein kinase PDK1. Science 1998;281: 2042-5. (Pubitemid 28475494)
    • (1998) Science , vol.281 , Issue.5385 , pp. 2042-2045
    • Le Good, J.A.1    Ziegler, W.H.2    Parekh, D.B.3    Alessi, D.R.4    Cohen, P.5    Parker, P.J.6
  • 5
    • 0034328882 scopus 로고    scopus 로고
    • The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters
    • Moscat J, Diaz-Meco MT. The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters. EMBO Rep 2000;1:399-403.
    • (2000) EMBO Rep , vol.1 , pp. 399-403
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 7
    • 25444531988 scopus 로고    scopus 로고
    • Atypical protein kinase Cι is an oncogene in human non-small cell lung cancer
    • DOI 10.1158/0008-5472.CAN-05-2372
    • Regala RP, Weems C, Jamieson L, Khoor A, Edell ES, LohseCM, et al. Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer. Cancer Res 2005;65:8905-11. (Pubitemid 41377380)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8905-8911
    • Regala, R.P.1    Weems, C.2    Jamieson, L.3    Khoor, A.4    Edell, E.S.5    Lohse, C.M.6    Fields, A.P.7
  • 8
    • 33646418390 scopus 로고    scopus 로고
    • Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma
    • Zhang L, Huang J, Yang N, Liang S, Barchetti A, Giannakakis A, et al. Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma. Cancer Res 2006;66:4627-35.
    • (2006) Cancer Res , vol.66 , pp. 4627-4635
    • Zhang, L.1    Huang, J.2    Yang, N.3    Liang, S.4    Barchetti, A.5    Giannakakis, A.6
  • 9
    • 38049074935 scopus 로고    scopus 로고
    • Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma
    • Yang YL, Chu JY, Luo ML, Wu YP, Zhang Y, Feng YB, et al. Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma. Genes Chromosomes Cancer 2008;47:127-36.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 127-136
    • Yang, Y.L.1    Chu, J.Y.2    Luo, M.L.3    Wu, Y.P.4    Zhang, Y.5    Feng, Y.B.6
  • 10
    • 77950250455 scopus 로고    scopus 로고
    • Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis
    • Scotti ML, Bamlet WR, Smyrk TC, Fields AP, Murray NR. Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis. Cancer Res 2010;70:2064-74.
    • (2010) Cancer Res , vol.70 , pp. 2064-2074
    • Scotti, M.L.1    Bamlet, W.R.2    Smyrk, T.C.3    Fields, A.P.4    Murray, N.R.5
  • 11
    • 46749127419 scopus 로고    scopus 로고
    • Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis
    • DOI 10.2353/ajpath.2008.070957
    • Fujita T, Liu W, Doihara H, Wan Y. Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. Am J Pathol 2008;173:217-28. (Pubitemid 351947969)
    • (2008) American Journal of Pathology , vol.173 , Issue.1 , pp. 217-228
    • Fujita, T.1    Liu, W.2    Doihara, H.3    Wan, Y.4
  • 13
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1999;1:193-9. (Pubitemid 129500937)
    • (1999) Nature Cell Biology , vol.1 , Issue.4 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 16
    • 58649121716 scopus 로고    scopus 로고
    • Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma
    • Wang XC, Wu YP, Ye B, Lin DC, Feng YB, Zhang ZQ, et al. Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma. Mol Cancer Res 2009;7:12-22.
    • (2009) Mol Cancer Res , vol.7 , pp. 12-22
    • Wang, X.C.1    Wu, Y.P.2    Ye, B.3    Lin, D.C.4    Feng, Y.B.5    Zhang, Z.Q.6
  • 17
    • 1642378661 scopus 로고    scopus 로고
    • Cdh1 ubiquitin ligase
    • DOI 10.1038/nature02330
    • Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C (Cdh1) ubiquitin ligase. Nature 2004;428:190-3. (Pubitemid 38374316)
    • (2004) Nature , vol.428 , Issue.6979 , pp. 190-193
    • Bashir, T.1    Dorello, H.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 18
    • 1642399624 scopus 로고    scopus 로고
    • Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
    • DOI 10.1038/nature02381
    • Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG Jr. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 2004;428: 194-8. (Pubitemid 38374317)
    • (2004) Nature , vol.428 , Issue.6979 , pp. 194-198
    • Wei, W.1    Ayad, N.G.2    Wan, Y.3    Zhang, G.-J.4    Kirschner, M.W.5    Kaelin Jr., W.G.6
  • 19
    • 42149190639 scopus 로고    scopus 로고
    • Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells
    • DOI 10.1242/jcs.016246
    • Wald FA, Oriolo AS, Mashukova A, Fregien NL, Langshaw AH, Salas PJ. Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells. J Cell Sci 2008;121: 644-54. (Pubitemid 351524163)
    • (2008) Journal of Cell Science , vol.121 , Issue.5 , pp. 644-654
    • Wald, F.A.1    Oriolo, A.S.2    Mashukova, A.3    Fregien, N.L.4    Langshaw, A.H.5    Salas, P.J.I.6
  • 20
    • 18144429360 scopus 로고    scopus 로고
    • Survival function of protein kinase Cι, as a novel nitrosamine 4-(methylinitrosamino) -1-(3-pyridyl)-1-butanone-activated bad kinase
    • DOI 10.1074/jbc.M413488200
    • Jin Z, Xin M, Deng X. Survival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanoneactivated bad kinase. J Biol Chem 2005;280:16045-52. (Pubitemid 40616729)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.16 , pp. 16045-16052
    • Jin, Z.1    Xin, M.2    Deng, X.3
  • 22
    • 0035831463 scopus 로고    scopus 로고
    • CD44 interaction with c- Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration
    • Bourguignon LY, Zhu H, Shao L, Chen YW. CD44 interaction with c- Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration. J Biol Chem 2001;276:7327-36.
    • (2001) J Biol Chem , vol.276 , pp. 7327-736
    • Bourguignon, L.Y.1    Zhu, H.2    Shao, L.3    Chen, Y.W.4
  • 24
    • 58149294015 scopus 로고    scopus 로고
    • Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma
    • Feng YB, Lin DC, Shi ZZ, Wang XC, Shen XM, Zhang Y, et al. Overexpression of PLK1 is associated with poor survival by inhibiting apoptosis via enhancement of survivin level in esophageal squamous cell carcinoma. Int J Cancer 2009;124:578-88.
    • (2009) Int J Cancer , vol.124 , pp. 578-588
    • Feng, Y.B.1    Lin, D.C.2    Shi, Z.Z.3    Wang, X.C.4    Shen, X.M.5    Zhang, Y.6
  • 25
    • 0038581169 scopus 로고    scopus 로고
    • Changing neighbours, changing behaviour: Cell adhesion molecule-mediated signalling during tumour progression
    • DOI 10.1093/emboj/cdg228
    • Christofori G. Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumor progression. EMBO J 2003;22:2318-23. (Pubitemid 36604971)
    • (2003) EMBO Journal , vol.22 , Issue.10 , pp. 2318-2323
    • Christofori, G.1
  • 26
    • 33846225205 scopus 로고    scopus 로고
    • Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance
    • DOI 10.1158/0008-5472.CAN-06-1484
    • Luo ML, Shen XM, Zhang Y, Wei F, Xu X, Cai Y, et al. Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance. Cancer Res 2006;66:11690-9. (Pubitemid 46094181)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11690-11699
    • Luo, M.-L.1    Shen, X.-M.2    Zhang, Y.3    Wei, F.4    Xu, X.5    Cai, Y.6    Zhang, X.7    Sun, Y.-T.8    Zhan, Q.-M.9    Wu, M.10    Wang, M.-R.11
  • 27
    • 70350566519 scopus 로고    scopus 로고
    • Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma
    • Du XL, Yang H, Liu SG, Luo ML, Hao JJ, Zhang Y, et al. Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma. Oncogene 2009;28:3714-22.
    • (2009) Oncogene , vol.28 , pp. 3714-3722
    • Du, X.L.1    Yang, H.2    Liu, S.G.3    Luo, M.L.4    Hao, J.J.5    Zhang, Y.6
  • 28
    • 33645920300 scopus 로고    scopus 로고
    • PI3K/Akt signaling regulates p27kip1 expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27kip1 regulation in LNCaP and PC346 cells
    • Van Duijn PW, Trapman J. PI3K/Akt signaling regulates p27kip1 expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27kip1 regulation in LNCaP and PC346 cells. Prostate 2006;66:749-60.
    • (2006) Prostate , vol.66 , pp. 749-760
    • Van Duijn, P.W.1    Trapman, J.2
  • 29
    • 34249335357 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells
    • DOI 10.1158/0008-5472.CAN-06-4484
    • Reichert M, Saur D, Hamacher R, Schmid RM, Schneider G. Phosphoinositide- 3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells. Cancer Res 2007;67:4149-56. (Pubitemid 46815060)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4149-4156
    • Reichert, M.1    Saur, D.2    Hamacher, R.3    Schmid, R.M.4    Schneider, G.5
  • 31
    • 33644620310 scopus 로고    scopus 로고
    • Protein kinase Cι promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of μ- and m-calpains
    • DOI 10.1074/jbc.M510721200
    • Xu L, Deng X. Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and mcalpains. J Biol Chem 2006;281:4457-66. (Pubitemid 43847877)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.7 , pp. 4457-4466
    • Xu, L.1    Deng, X.2
  • 32
    • 44449112209 scopus 로고    scopus 로고
    • Regulation of glioblastoma cell invasion by PKCι and RhoB
    • DOI 10.1038/sj.onc.1211027, PII 1211027
    • Baldwin RM, Parolin DA, Lorimer IA. Regulation of glioblastoma cell invasion by PKC iota and RhoB. Oncogene 2008;27:3587-95. (Pubitemid 351793806)
    • (2008) Oncogene , vol.27 , Issue.25 , pp. 3587-3595
    • Baldwin, R.M.1    Parolin, D.A.E.2    Lorimer, I.A.J.3
  • 34
    • 33748052706 scopus 로고    scopus 로고
    • IKKα controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression
    • DOI 10.1038/sj.emboj.7601259, PII 7601259
    • Schneider G, Saur D, Siveke JT, Fritsch R, Greten F, Schmid RM. IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression. Embo J 2006;25:3801-12. (Pubitemid 44300266)
    • (2006) EMBO Journal , vol.25 , Issue.16 , pp. 3801-3812
    • Schneider, G.1    Saur, D.2    Siveke, J.T.3    Fritsch, R.4    Greten, F.R.5    Schmid, R.M.6
  • 35
    • 64049086572 scopus 로고    scopus 로고
    • Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
    • Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nat Cell Biol 2009;11:397-408.
    • (2009) Nat Cell Biol , vol.11 , pp. 397-408
    • Gao, D.1    Inuzuka, H.2    Tseng, A.3    Chin, R.Y.4    Toker, A.5    Wei, W.6
  • 36
    • 64049087382 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
    • Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, et al. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol 2009;11:420-32.
    • (2009) Nat Cell Biol , vol.11 , pp. 420-32
    • Lin, H.K.1    Wang, G.2    Chen, Z.3    Teruya-Feldstein, J.4    Liu, Y.5    Chan, C.H.6
  • 37
    • 0034533061 scopus 로고    scopus 로고
    • Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells
    • DOI 10.1042/0264-6021:3520475
    • Mao M, Fang X, Lu Y, Lapushin R, Bast RC Jr, Mills GB. Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells. Biochem J 2000;352:Pt 2, 475-82. (Pubitemid 32011441)
    • (2000) Biochemical Journal , vol.352 , Issue.2 , pp. 475-482
    • Mao, M.1    Fang, X.2    Lu, Y.3    LaPushin, R.4    Bast R.C., Jr.5    Mills, G.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.