Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

Nature Cell Biology

Volumn 11, Issue 4, 2009, Pages 397-408

  Gao, Daming ^a   Inuzuka, Hiroyuki ^a   Tseng, Alan ^a   Chin, Rebecca Y ^a   Toker, Alex ^a   Wei, Wenyi ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; PROTEIN KINASE B; PROTEIN KINASE B BETA; S PHASE KINASE ASSOCIATED PROTEIN 2; SERINE; UBIQUITIN PROTEIN LIGASE; UVOMORULIN;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANIMALS; CASEIN KINASE I; CYTOPLASM; HELA CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; S-PHASE KINASE-ASSOCIATED PROTEINS; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

EID: 64049086572     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1847     Document Type: Article

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