PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Cao, Yongheng ^a,h   Nakata, Masanori ^b   Okamoto, Shiki ^c   Takano, Eisuke ^b   Yada, Toshihiko ^b   Minokoshi, Yasuhiko ^c   Hirata, Yukio ^d   Nakajima, Kazunori ^d   Iskandar, Kristy ^a   Hayashi, Yoshitake ^a   Ogawa, Wataru ^a   Barsh, Gregory S ^e   Hosoda, Hiroshi ^f   Kangawa, Kenji ^f   Itoh, Hiroshi ^d   Noda, Tetsuo ^g   Kasuga, Masato ^e,h   Nakae, Jun ^a,d  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e STANFORD UNIVERSITY   (United States)

^f NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^g CANCER INSTITUTE   (Japan)

^h NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; CALCIUM ION; GHRELIN; INSULIN; LEPTIN; MELANOCORTIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; TRANSCRIPTION FACTOR FKHR; CALCIUM; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; NEUROPEPTIDE; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL TRANSFERRING) KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY HEIGHT; BODY WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; ENZYME INHIBITION; FEMALE; FOOD INTAKE; HOMEOSTASIS AND REGULATION; IN VITRO STUDY; INTRACELLULAR SIGNALING; LOCOMOTION; MALE; MOUSE; NERVE CELL; NONHUMAN; OXYGEN CONCENTRATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANIMAL; CALORIC RESTRICTION; CYTOLOGY; DRUG EFFECT; EATING; GENE INACTIVATION; GENETICS; HOMEOSTASIS; INTRACELLULAR SPACE; METABOLISM; PHENOTYPE; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

AGOUTI; MUS;

AGOUTI-RELATED PROTEIN; ANIMALS; CALCIUM; CALORIC RESTRICTION; EATING; ENERGY METABOLISM; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKOUT TECHNIQUES; GHRELIN; HOMEOSTASIS; INTRACELLULAR SPACE; LEPTIN; MALE; MELANOCORTINS; MICE; NEURONS; NEUROPEPTIDES; PHENOTYPE; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 79954455756     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018324     Document Type: Article

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