Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding

Journal of Biological Chemistry

Volumn 282, Issue 11, 2007, Pages 8265-8275

  Boura, Evzen ^a,b   Silhan, Jan ^a,b   Herman, Petr ^a   Vecer, Jaroslav ^a   Sulc, Miroslav ^a,c   Teisinger, Jan ^b   Obsilova, Veronika ^b   Obsil, Tomas ^a,b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^c INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING DOMAIN (DBD); GROWTH FACTORS; PROTEIN KINASE;

CHEMICAL BONDS; CYTOLOGY; ENERGY TRANSFER; GROWTH KINETICS; INSULIN; MEASUREMENT THEORY; MOLECULAR DYNAMICS; TRANSCRIPTION;

DNA SEQUENCES;

FORKHEAD TRANSCRIPTION FACTOR; PHOSPHOPROTEIN; PROTEIN KINASE B; DNA; MLLT7 PROTEIN, HUMAN; PROTEIN 14 3 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA BINDING; ENERGY TRANSFER; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; STATISTICAL SIGNIFICANCE; ANISOTROPY; CHEMICAL STRUCTURE; CHEMISTRY; GENE DELETION; HUMAN; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANISOTROPY; DNA; GENE DELETION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; TRANSCRIPTION FACTORS;

EID: 34247267098     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605682200     Document Type: Article

References (49)

1. Kaufmann, E., and Knochel, W. (1996) Mech. Dev. 57, 3-20
2. Lai, E., Clark, K. L., Burley, S. K., and Darnell, J. E., Jr. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10421-10423
3. Carlsson, P., and Mahlapuu, M. (2002) Dev. Biol. 250, 1-23
4. Kaestner, K. H., Knochel, W., and Martinez, D. E. (2000) Genes Dev. 14, 142-146
5. Clark, K. L., Halay, E. D., Lai, E., and Burley, S. K. (1993) Nature 364, 412-420
6. Jin, C., and Liao, X. (1999) J. Mol. Biol. 292, 641-651
7. Gajiwala, K. S., and Burley, S. K. (2000) Curr. Opin. Struct. Biol. 10, 110-116
8. Gajiwala, K. S., Chen, H., Cornille, F., Roques, B. P., Reith, W., Mach, B., and Burley, S. K. (2000) Nature 403, 916-921
9. Weigelt, J., Climent, I., Dahlman-Wright, K., and Wikstrom, M. (2001) Biochemistry 40, 5861-5869
10. Jin, C., Marsden, I., Chen, X., and Liao, X. (1999) J. Mol. Biol. 289, 683-690
11. Wolberger, C., and Campbell, R. (2000) Nat. Struct. Biol. 7, 261-262
12. Zheng, N., Fraenkel, E., Pabo, C. O., and Pavletich, N. P. (1999) Genes Dev. 13, 666-674
13. Pierrou, S., Hellqvist, M., Samuelsson, L., Enerback, S., and Carlsson, P. (1994) EMBO J. 13, 5002-5012
14. van Dongen, M. J., Cederberg, A., Carlsson, P., Enerback, S., and Wikstrom, M. (2000) J. Mol. Biol. 296, 351-359
15. Arden, K. C. (2004) Mol. Cell 14, 416-418
16. Burgering, B. M., and Kops, G. J. (2002) Trends Biochem. Sci. 27, 352-360
17. Van Der Heide, L. P., Hoekman, M. F., and Smidt, M. P. (2004) Biochem. J. 380, 297-309
18. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. (1999) Cell 96, 857-868
19. Woods, Y. L., and Rena, G. (2002) Biochem. Soc. Trans. 30, 391-397
20. Woods, Y. L., Rena, G., Morrice, N., Barthel, A., Becker, W., Guo, S., Unterman, T. G., and Cohen, P. (2001) Biochem. J. 355, 597-607
21. Rena, G., Woods, Y. L., Prescott, A. R., Peggie, M., Unterman, T. G., Williams, M. R., and Cohen, P. (2002) EMBO J. 21, 2263-2271
22. Cahill, C. M., Tzivion, G., Nasrin, N., Ogg, S., Dore, J., Ruvkun, G., and Alexander-Bridges, M. (2001) J. Biol. Chem. 276, 13402-13410
23. Obsil, T., Ghirlando, R., Anderson, D. E., Hickman, A. B., and Dyda, F. (2003) Biochemistry 42, 15264-15272
24. Zhao, X., Gan, L., Pan, H., Kan, D., Majeski, M., Adam, S. A., and Unterman, T. G. (2004) Biochem. J. 378, 839-849
25. Brownawell, A. M., Kops, G. J., Macara, I. G., and Burgering, B. M. (2001) Mol. Cell. Biol. 21, 3534-3546
26. Brunet, A., Kanai, F., Stehn, J., Xu, J., Sarbassova, D., Frangioni, J. V., Dalal, S. N., DeCaprio, J. A., Greenberg, M. E., and Yaffe, M. B. (2002) J. Cell Biol. 156, 817-828
27. Obsilova, V., Vecer, J., Herman, P., Pabianova, A., Sulc, M., Teisinger, J., Boura, E., and Obsil, T. (2005) Biochemistry 44, 11608-11617
28. Zhang, X., Gan, L., Pan, H., Guo, S., He, X., Olson, S. T., Mesecar, A., Adam, S., and Unterman, T. G. (2002) J. Biol. Chem. 277, 45276-45284
29. Lai, E., Prezioso, V. R., Smith, E., Litvin, O., Costa, R. H., and Darnell, J. E., Jr. (1990) Genes Dev. 4, 1427-1436
30. van der Heide, L. P., Jacobs, F. M., Burbach, J. P., Hoekman, M. F., and Smidt, M. P. (2005) Biochem. J. 391, 623-629
31. Kovarova, H., Halada, P., Man, P., Golovliov, I., Krocova, Z., Spacek, J., Porkertova, S., and Necasova, R. (2002) Proteomics 2, 85-93
32. Silhan, J., Obsilova, V., Vecer, J., Herman, P., Sulc, M., Teisinger, J., and Obsil, T. (2004) J. Biol. Chem. 279, 49113-49119
33. Obsil, T., Ghirlando, R., Klein, D. C., Ganguly, S., and Dyda, F. (2001) Cell 105, 257-267
34. Kohler, J. J., and Schepartz, A. (2001) Biochemistry 40, 130-142
35. Obsilova, V., Herman, P., Vecer, J., Sulc, M., Teisinger, J., and Obsil, T. (2004) J. Biol. Chem. 279, 4531-4540
36. Squier, T. C., Bigelow, D. J., Deancos, J. G., and Inesi, G. (1987) J. Biol. Chem. 262, 4748-4754
37. Birmachu, W., Nisswandt, F. L., and Thomas, D. D. (1989) Biochemistry 28, 3940-3947
38. Sorin, E. J., and Pande, V. S. (2005) Biophys. J. 88, 2472-2493
39. Lu, X. J., and Olson, W. K. (2003) Nucleic Acids Res. 31, 5108-5121
40. Jorgensen, W. L., Chandrasekhar, J., Madura, J. D., Impey, R. W., and Klein, M. L. (1983) J. Chem. Phys. 79, 926-935
41. Berendsen, H. J. C., Postma, J. P. M., Vangunsteren, W. F., Dinola, A., and Haak, J. R. (1984) J. Chem. Phys. 81, 3684-3690
42. Hess, B., Bekker, H., Berendsen, H. J. C., and Fraaije, J. G. E. M. (1997) J. Comput. Chem. 18, 1463-1472
43. Darden, T., York, D., and Pedersen, L. (1993) J. Chem. Phys. 98, 10089-10092
44. Van der Spoel, D., Lindahl, E., Hess, B., Groenhof, G., Mark, A. E., and Berendsen, H. J. C. (2005) J. Comput. Chem. 26, 1701-1718
45. Daura, X., Gademann, K., Jaun, B., Seebach, D., van Gunsteren, W. F., and Mark, A. E. (1999) Angew. Chem. Int. Ed. Engl. 38, 236-240
46. Norman, D. G., Grainger, R. J., Uhrin, D., and Lilley, D. M. (2000) Biochemistry 39, 6317-6324
47. Clegg, R. M., Murchie, A. I., Zechel, A., and Lilley, D. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2994-2998
48. Yaffe, M. B., Rittinger, K., Volinia, S., Caron, P. R., Aitken, A., Leffers, H., Gamblin, S. J., Smerdon, S. J., and Cantley, L. C. (1997) Cell 91, 961-971
49. Humphrey, W., Dalke, A., and Schulten, K. (1996) J. Mol. Graphics 14, 33-8, 27-8