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Volumn 134, Issue 3, 2011, Pages 584-607

Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases

Author keywords

Cardiovascular diseases; Diabetes; Gegen; Kudzu root; Metabolic syndrome; Pueraria lobata; Pueraria thomsonii; Traditional Chinese medicine

Indexed keywords

3' HYDROXY 4' O BETA GLUCOSYLPUERARIN; 3' HYDROXYPUERARIN; 3' HYDROXYPUERARIN 4' O DEOXYHEXOSIDE; 3' METHOXYDAIDZEIN 7 O METHYL ETHER; 3' METHOXYDAIDZIN; 3' METHOXYPUERARIN; 4' GLUCOSYLDAIDZIN; 4' METHOXYPUERARIN; 6'' O XYLOSYLPUERARIN; BIOCHANIN A; COUMARIN DERIVATIVE; COUMESTROL; DAIDZEIN; DAIDZEIN 7 O METHYL ETHER; DAIDZIN; FORMONONETIN; GENISTEIN; ISOFLAVONOID; KUZUBUTENOLIDE A; PUERARIA EXTRACT; PUERARIA LOBATA EXTRACT; PUERARIN; PUERARIN 4' O GLUCOSIDE; PUERAROL; PUEROL B; PUEROSIDE A; PUEROSIDE B; SCOPARONE; TRITERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 79954422522     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2011.02.001     Document Type: Review
Times cited : (328)

References (214)
  • 1
    • 79954415048 scopus 로고    scopus 로고
    • Amazon Kudzu. Amazon.com Inc. Accessed 7 January 2011. Available at
    • Amazon, 2011. Kudzu. Amazon.com Inc. Accessed 7 January 2011. Available at: http://www.amazon.com/s/ref=nb-sb-noss?url=search-alias%3Dhpc&field- keywords=kudzu&x=0&y=0.
    • (2011)
  • 2
    • 27544434452 scopus 로고    scopus 로고
    • Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women
    • E. Anupongsanugool, S. Teekachunhatean, N. Rojanasthien, S. Pongsatha, and C. Sangdee Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women BMC Clinical Pharmacology 5 2005 2
    • (2005) BMC Clinical Pharmacology , vol.5 , pp. 2
    • Anupongsanugool, E.1    Teekachunhatean, S.2    Rojanasthien, N.3    Pongsatha, S.4    Sangdee, C.5
  • 3
    • 0029025955 scopus 로고
    • Oleanene-type triterpene glycosides from Puerariae Radix, II. Isolation of saponins and the application of tandem mass spectrometry to their structure determination
    • T. Arao, J. Kinjo, T. Nohara, and R. Isobe Oleanene-type triterpene glycosides from Puerariae Radix, II. Isolation of saponins and the application of tandem mass spectrometry to their structure determination Chemical & Pharmaceutical Bulletin 43 1995 1176 1179
    • (1995) Chemical & Pharmaceutical Bulletin , vol.43 , pp. 1176-1179
    • Arao, T.1    Kinjo, J.2    Nohara, T.3    Isobe, R.4
  • 4
    • 0030891956 scopus 로고    scopus 로고
    • Oleanene-type triterpene glycosides from Puerariae Radix. IV. Six new saponins from Pueraria lobata
    • T. Arao, J. Kinjo, T. Nohara, and R. Isobe Oleanene-type triterpene glycosides from puerariae radix IV. Six new saponins from Pueraria lobata Chemical & Pharmaceutical Bulletin 45 1997 362 366 (Pubitemid 27131864)
    • (1997) Chemical and Pharmaceutical Bulletin , vol.45 , Issue.2 , pp. 362-366
    • Arao, T.1    Kinjo, J.2    Nohara, T.3    Isobe, R.4
  • 5
    • 49149104567 scopus 로고    scopus 로고
    • Etiology, pathophysiology, and treatment of atrial fibrillation: Part 1
    • W.S. Aronow Etiology, pathophysiology, and treatment of atrial fibrillation: part 1 Cardiology in Review 16 2008 181 188
    • (2008) Cardiology in Review , vol.16 , pp. 181-188
    • Aronow, W.S.1
  • 7
    • 0027085867 scopus 로고
    • Mechanisms of excitotoxicity in neurologic diseases
    • M.F. Beal Mechanisms of excitotoxicity in neurologic diseases The FASEBJ Journal 6 1992 3338 3344 (Pubitemid 23007098)
    • (1992) FASEB Journal , vol.6 , Issue.15 , pp. 3338-3344
    • Beal, M.F.1
  • 9
    • 70349859675 scopus 로고    scopus 로고
    • Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications
    • A. Bierhaus, and P.P. Nawroth Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications Diabetologia 52 2009 2251 2263
    • (2009) Diabetologia , vol.52 , pp. 2251-2263
    • Bierhaus, A.1    Nawroth, P.P.2
  • 10
    • 24044443879 scopus 로고    scopus 로고
    • Protection by puerarin against MPP+-induced neurotoxicity in PC12 cells mediated by inhibiting mitochondrial dysfunction and caspase-3-like activation
    • DOI 10.1016/j.neures.2005.06.014, PII S0168010205001847
    • J. Bo, B.Y. Ming, L.Z. Gang, C. Lei, and A.L. Jia Protection by puerarin against MPP+-induced neurotoxicity in PC12 cells mediated by inhibiting mitochondrial dysfunction and caspase-3-like activation Neuroscience Research 53 2005 183 188 (Pubitemid 41219535)
    • (2005) Neuroscience Research , vol.53 , Issue.2 , pp. 183-188
    • Bo, J.1    Bao, Y.M.2    Li, Z.G.3    Lei, C.4    An, L.J.5
  • 13
    • 57649111589 scopus 로고    scopus 로고
    • Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: Clinical implications
    • C.P. Cannon Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: clinical implications American Journal of Cardiology 102 2008 5L 9L
    • (2008) American Journal of Cardiology , vol.102
    • Cannon, C.P.1
  • 14
    • 0032848459 scopus 로고    scopus 로고
    • Separation and purification of isoflavones from Pueraria lobata by high-speed counter-current chromatography
    • DOI 10.1016/S0021-9673(99)00715-3, PII S0021967399007153
    • X. Cao, Y. Tian, T. Zhang, X. Li, and Y. Ito Separation and purification of isoflavones from Pueraria lobata by high-speed counter-current chromatography Journal of Chromatography A 855 1999 709 713 (Pubitemid 29413083)
    • (1999) Journal of Chromatography A , vol.855 , Issue.2 , pp. 709-713
    • Cao, X.1    Tian, Y.2    Zhang, T.3    Li, X.4    Ito, Y.5
  • 15
    • 0036134038 scopus 로고    scopus 로고
    • Molecular mechanisms of gating and drug block of sodium channels
    • W.A. Catterall Molecular mechanisms of gating and drug block of sodium channels Novartis Foundation Symposium 241 2002 206 218
    • (2002) Novartis Foundation Symposium , vol.241 , pp. 206-218
    • Catterall, W.A.1
  • 16
    • 0028997733 scopus 로고
    • Progress in traditional Chinese medicine
    • K. Chan Progress in traditional Chinese medicine Trends in Pharmacological Sciences 16 1995 182 187
    • (1995) Trends in Pharmacological Sciences , vol.16 , pp. 182-187
    • Chan, K.1
  • 17
    • 9644284419 scopus 로고    scopus 로고
    • Chinese medicinal materials and their interface with Western medical concepts
    • DOI 10.1016/j.jep.2004.09.019, PII S0378874104004507
    • K. Chan Chinese medicinal materials and their interface with Western medical concepts Journal of Ethnopharmacology 96 2005 1 18 (Pubitemid 39575027)
    • (2005) Journal of Ethnopharmacology , vol.96 , Issue.1-2 , pp. 1-18
    • Chan, K.1
  • 19
    • 70350243047 scopus 로고    scopus 로고
    • Impact effects of puerarin on mouse embryonic development
    • C.C. Chen, and W.H. Chan Impact effects of puerarin on mouse embryonic development Reproductive Toxicology 28 2009 530 535
    • (2009) Reproductive Toxicology , vol.28 , pp. 530-535
    • Chen, C.C.1    Chan, W.H.2
  • 20
    • 77953385099 scopus 로고    scopus 로고
    • Determination of pueraria isoflavones in Pueraria thomsonii and Pueraria lobata by HPLC reference fingerprint chromatogram and Folin-phenol reagent colorimetry
    • J. Chen, M. Song, Y. Zhang, S. Zhang, and T. Hang Determination of pueraria isoflavones in Pueraria thomsonii and Pueraria lobata by HPLC reference fingerprint chromatogram and Folin-phenol reagent colorimetry Chinese Journal of New Drugs 17 2008 1240 1246 (in Chinese)
    • (2008) Chinese Journal of New Drugs , vol.17 , pp. 1240-1246
    • Chen, J.1    Song, M.2    Zhang, Y.3    Zhang, S.4    Hang, T.5
  • 22
    • 34248334280 scopus 로고    scopus 로고
    • Seasonal variations in the isoflavonoids of Radix Puerariae
    • DOI 10.1002/pca.978
    • S. Chen, D. Yang, S. Chen, H. Xu, and A.S. Chan Seasonal variations in the isoflavonoids of radix Puerariae Phytochemical Analysis 18 2007 245 250 (Pubitemid 46730264)
    • (2007) Phytochemical Analysis , vol.18 , Issue.3 , pp. 245-250
    • Sibao, C.1    Dajian, Y.2    Shilin, C.3    Hongxi, X.4    Chan, A.S.C.5
  • 23
    • 33744981186 scopus 로고    scopus 로고
    • High-performance thin-layer chromatographic fingerprints of isoflavonoids for distinguishing between Radix Puerariae Lobate and Radix Puerariae Thomsonii
    • DOI 10.1016/j.chroma.2006.04.082, PII S0021967306007588
    • S.B. Chen, H.P. Liu, R.T. Tian, D.J. Yang, S.L. Chen, H.X. Xu, A.S. Chan, and P.S. Xie High-performance thin-layer chromatographic fingerprints of isoflavonoids for distinguishing between Radix Puerariae Lobate and Radix Puerariae Thomsonii Journal of Chromatography A 1121 2006 114 119 (Pubitemid 43867532)
    • (2006) Journal of Chromatography A , vol.1121 , Issue.1 , pp. 114-119
    • Chen, S.-B.1    Liu, H.-P.2    Tian, R.-T.3    Yang, D.-J.4    Chen, S.-L.5    Xu, H.-X.6    Chan, A.S.C.7    Xie, P.-S.8
  • 24
    • 1542284226 scopus 로고    scopus 로고
    • Mediation of β-endorphin by the isoflavone puerarin to lower plasma glucose in streptozotocin-induced diabetic rats
    • DOI 10.1055/s-2004-815486
    • W.C. Chen, S. Hayakawa, T. Yamamoto, H.C. Su, I.M. Liu, and J.T. Cheng Mediation of beta-endorphin by the isoflavone puerarin to lower plasma glucose in streptozotocin-induced diabetic rats Planta Medica 70 2004 113 116 (Pubitemid 38299771)
    • (2004) Planta Medica , vol.70 , Issue.2 , pp. 113-116
    • Chen, W.-C.1    Hayakawa, S.2    Yamamoto, T.3    Su, H.-C.4    Liu, I.-M.5    Cheng, J.-T.6
  • 25
    • 0033673746 scopus 로고    scopus 로고
    • Review: Drug therapy in chinese traditional medicine
    • J. Cheng Review: drug therapy in chinese traditional medicine The Journal of Clinical Pharmacology 40 2000 445 450
    • (2000) The Journal of Clinical Pharmacology , vol.40 , pp. 445-450
    • Cheng, J.1
  • 26
    • 0035829017 scopus 로고    scopus 로고
    • Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro
    • J.T. Cheng, I.M. Liu, D.H. Kuo, and M.T. Lin Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro Autonomic Neuroscience 93 2001 31 35
    • (2001) Autonomic Neuroscience , vol.93 , pp. 31-35
    • Cheng, J.T.1    Liu, I.M.2    Kuo, D.H.3    Lin, M.T.4
  • 28
    • 44049108337 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonists and diabetes: Current evidence and future perspectives
    • F. Chiarelli, and D. Di Marzio Peroxisome proliferator-activated receptor-gamma agonists and diabetes: current evidence and future perspectives Vascular Health & Risk Management 4 2008 297 304 (Pubitemid 351711958)
    • (2008) Vascular Health and Risk Management , vol.4 , Issue.2 , pp. 297-304
    • Chiarelli, F.1    Di Marzio, D.2
  • 29
    • 0036783198 scopus 로고    scopus 로고
    • Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora
    • M.K. Choo, E.K. Park, H.K. Yoon, and D.H. Kim Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora Biological & Pharmaceutical Bulletin 25 2002 1328 1332
    • (2002) Biological & Pharmaceutical Bulletin , vol.25 , pp. 1328-1332
    • Choo, M.K.1    Park, E.K.2    Yoon, H.K.3    Kim, D.H.4
  • 30
    • 37349064399 scopus 로고    scopus 로고
    • Antioxidative and hypocholesterolemic activities of water-soluble puerarin glycosides in HepG2 cells and in C57 BL/6J mice
    • DOI 10.1016/j.ejphar.2007.09.036, PII S0014299907010941
    • M.J. Chung, N.J. Sung, C.S. Park, D.K. Kweon, A. Moantovani, T.W. Moon, S.J. Lee, and K.H. Park Antioxidant and hypercholesterolemic activities of water-soluble puerarin glycosides in HepG2 cells and in C57/6J mice European Journal of Pharmacology 578 2008 159 170 (Pubitemid 350309595)
    • (2008) European Journal of Pharmacology , vol.578 , Issue.2-3 , pp. 159-170
    • Chung, M.J.1    Sung, N.-J.2    Park, C.-S.3    Kweon, D.-K.4    Mantovani, A.5    Moon, T.-W.6    Lee, S.-J.7    Park, K.-H.8
  • 35
    • 0041667223 scopus 로고    scopus 로고
    • Effects of puerarin against glutamate excitotoxicity on cultured mouse cerebral cortical neurons
    • L.P. Dong, and T.Y. Wang Effects of puerarin against glutamate excitotoxicity on cultured mouse cerebral cortical neurons Acta Pharmacological Sinica 19 1998 339 342
    • (1998) Acta Pharmacological Sinica , vol.19 , pp. 339-342
    • Dong, L.P.1    Wang, T.Y.2
  • 36
    • 79954420285 scopus 로고    scopus 로고
    • DPI&F Department of Primary Industries and Fisheries, Queensland, Australia
    • DPI&F, 2008. Fact Sheet: Declared plants of Queensland. Department of Primary Industries and Fisheries, Queensland, Australia.
    • (2008) Fact Sheet: Declared Plants of Queensland
  • 37
    • 9744284320 scopus 로고    scopus 로고
    • Effects of puerarin on renal function, expressions of MMP-2 and TIMP-2 in diabetic rats
    • H. Duan, S. Liu, Y. Zhang, Q. Liu, N. He, and Y. Li Effects of puerarin on renal function, expressions of MMP-2 and TIMP-2 in diabetic rats Yao Hsueh Hsueh Bao/Acta Pharmaceutica Sinica 39 2004 481 485 (in Chinese) (Pubitemid 39586385)
    • (2004) Yaoxue Xuebao , vol.39 , Issue.7 , pp. 481-485
    • Duan, H.-J.1    Liu, S.-X.2    Zhang, Y.-J.3    Liu, Q.-J.4    He, N.5    Li, Y.-M.6
  • 38
    • 34249852075 scopus 로고    scopus 로고
    • Acute ischemic stroke: Overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia
    • DOI 10.1016/j.pbb.2007.04.015, PII S0091305707001372
    • A. Durukan, and T. Tatlisumak Acute ischaemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischaemia Pharmacology, Biochemistry & Behavior 87 2007 179 197 (Pubitemid 46860315)
    • (2007) Pharmacology Biochemistry and Behavior , vol.87 , Issue.1 , pp. 179-197
    • Durukan, A.1    Tatlisumak, T.2
  • 39
    • 17144380822 scopus 로고    scopus 로고
    • The metabolic syndrome
    • DOI 10.1016/S0140-6736(05)66378-7
    • R.H. Eckel, S.M. Grundy, and P.Z. Zimmet The metabolic syndrome Lancet 365 2005 1415 1428 (Pubitemid 40523737)
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1415-1428
    • Eckel, R.H.1    Grundy, S.M.2    Zimmet, P.Z.3
  • 40
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • DOI 10.1038/nrn1106
    • H.L. Eng, T. Dalkara, and M.A. Moskowitz Mechanisms, challenges and opportunities in stroke Nature Neuroscience 4 2003 399 415 (Pubitemid 37280178)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.5 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 43
    • 0022295232 scopus 로고
    • Pharmacologic studies on Radix puerariae. Effect of puerarin on regional myocardial blood flow and cardiac hemodynamics in dogs with acute myocardial ischemia
    • L. Fan, D.O. Dennis, and W.J.P. Wand Pharmacologic studies on Radix Puerariae, Effect of puerarin on regional myocardial blood flow and cardiac hemodynamics in dogs with acute myocardial ischaemia Chinese Medical Journal 98 1985 821 832 (Pubitemid 16152238)
    • (1985) Chinese Medical Journal , vol.98 , Issue.11 , pp. 821-832
    • Fan Li-li1    O'Keefe, D.D.2    Powell Jr., J.3
  • 45
    • 33744742923 scopus 로고    scopus 로고
    • Identification of isoflavonoids in several kudzu samples by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
    • C. Fang, X. Wan, H. Tan, and C. Jiang Identification of isoflavonoids in several kudzu samples by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry Journal of Chromatographic Science 44 2006 57 63 (Pubitemid 43824694)
    • (2006) Journal of Chromatographic Science , vol.44 , Issue.2 , pp. 57-63
    • Fang, C.1    Wan, X.2    Tan, H.3    Jiang, C.4
  • 46
    • 0018895337 scopus 로고
    • Some current study and research approaches relating to the use of plants in the traditional Chinese medicine
    • Q. Fang Some current study and research approaches relating to the use of plants in the traditional Chinese medicine Journal of Ethnopharmacology 2 1980 57 63
    • (1980) Journal of Ethnopharmacology , vol.2 , pp. 57-63
    • Fang, Q.1
  • 47
    • 43049120038 scopus 로고    scopus 로고
    • Physiological modulation of voltage-dependent inactivation in the cardiac muscle L-type calcium channel: A modelling study
    • DOI 10.1016/j.pbiomolbio.2007.07.002, PII S007961070700051X
    • I. Findlay, S. Suzuki, S. Murakami, and Y. Kurachi Physiological modulation of voltage-dependent inactivation in the cardiac muscle L-type calcium channel: a modelling study Progress in Biophysics & Molecular Biology 96 2008 482 498 (Pubitemid 351625283)
    • (2008) Progress in Biophysics and Molecular Biology , vol.96 , Issue.1-3 , pp. 482-498
    • Findlay, I.1    Suzuki, S.2    Murakami, S.3    Kurachi, Y.4
  • 49
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
    • E.S. Ford, W.H. Giles, and W.H. Dietz Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey JAMA 287 2002 356 359 (Pubitemid 34251969)
    • (2002) Journal of the American Medical Association , vol.287 , Issue.3 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 50
    • 4644279733 scopus 로고    scopus 로고
    • Increasing prevalence of the metabolic syndrome among U.S. adults
    • DOI 10.2337/diacare.27.10.2444
    • E.S. Ford, W.H. Giles, and A.H. Mokdad Increasing prevalence of the metabolic syndrome among U.S. adults Diabetes Care 27 2004 2444 2449 (Pubitemid 39281399)
    • (2004) Diabetes Care , vol.27 , Issue.10 , pp. 2444-2449
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 51
    • 0028972025 scopus 로고
    • 15-deoxy-delta12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARgamma
    • DOI 10.1016/0092-8674(95)90193-0
    • B.M. Forman, P. Tontonoz, J. Chen, R.P. Brun, B.M. Spiegelman, and R.M. Evans 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma Cell 83 1995 803 812 (Pubitemid 3006324)
    • (1995) Cell , vol.83 , Issue.5 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 52
    • 67149102151 scopus 로고    scopus 로고
    • Puerarin protects against ischaemic brain injury in a rat model of transient focal ischaemia
    • L. Gao, X. Ji, J. Song, P. Liu, W. Gong, S. Dang, and Y. Lau Puerarin protects against ischaemic brain injury in a rat model of transient focal ischaemia Neurological Research 31 2009 402 406
    • (2009) Neurological Research , vol.31 , pp. 402-406
    • Gao, L.1    Ji, X.2    Song, J.3    Liu, P.4    Gong, W.5    Dang, S.6    Lau, Y.7
  • 53
    • 33646890644 scopus 로고    scopus 로고
    • Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart
    • DOI 10.1016/j.lfs.2005.12.040, PII S0024320506000142
    • Q. Gao, H.Y. Pan, S. Qiu, Y. Lu, I.C. Bruce, J.H. Luo, and Q. Xia Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart Life Sciences 79 2006 217 224 (Pubitemid 43782549)
    • (2006) Life Sciences , vol.79 , Issue.3 , pp. 217-224
    • Gao, Q.1    Pan, H.-Y.2    Qiu, S.3    Lu, Y.4    Bruce, I.C.5    Luo, J.-H.6    Xia, Q.7
  • 54
    • 35348870371 scopus 로고    scopus 로고
    • Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin
    • DOI 10.1016/j.ejphar.2007.07.018, PII S0014299907007972
    • Q. Gao, B. Yang, Z.G. Ye, J. Wang, I.C. Bruce, and Q. Xia Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin European Journal of Pharmacology 574 2007 179 184 (Pubitemid 47575526)
    • (2007) European Journal of Pharmacology , vol.574 , Issue.2-3 , pp. 179-184
    • Gao, Q.1    Yang, B.2    Ye, Z.-g.3    Wang, J.4    Bruce, I.C.5    Xia, Q.6
  • 55
    • 1842831084 scopus 로고    scopus 로고
    • Clinical management of metabolic syndrome: Report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management
    • American Heart A. National Heart L. Blood I. American Diabetes A.
    • S.M. Grundy, B. Hansen, S.C. Smith Jr., J.I. Cleeman, R.A. Kahn, A. American Heart, L. National Heart, I. Blood, and A. American Diabetes Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management Arteriosclerosis, Thrombosis & Vascular Biology 24 2004 e19 24
    • (2004) Arteriosclerosis, Thrombosis & Vascular Biology , vol.24 , pp. 19-24
    • Grundy, S.M.1    Hansen, B.2    Smith Jr., S.C.3    Cleeman, J.I.4    Kahn, R.A.5
  • 56
    • 0034602337 scopus 로고    scopus 로고
    • Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism
    • M.C. Guerra, E. Speroni, M. Broccoli, M. Cangini, P. Pasini, A. Minghett, N. Crespi-Perellino, M. Mirasoli, G. Cantelli-Forti, and M. Paolini Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism Life Sciences 67 2000 2997 3006
    • (2000) Life Sciences , vol.67 , pp. 2997-3006
    • Guerra, M.C.1    Speroni, E.2    Broccoli, M.3    Cangini, M.4    Pasini, P.5    Minghett, A.6    Crespi-Perellino, N.7    Mirasoli, M.8    Cantelli-Forti, G.9    Paolini, M.10
  • 58
    • 0016714188 scopus 로고
    • Pharmacological studies on pueraria root, I. Fractional extraction of pueraria root and identification of its pharmacological effects
    • M. Harada, and K. Ueno Pharmacological studies on pueraria root, I. Fractional extraction of pueraria root and identification of its pharmacological effects Chemical & Pharmaceutical Bulletin 23 1975 1798 1805
    • (1975) Chemical & Pharmaceutical Bulletin , vol.23 , pp. 1798-1805
    • Harada, M.1    Ueno, K.2
  • 59
    • 79954419751 scopus 로고    scopus 로고
    • Healthstore Healthstore.uk.com Accessed 7 January 2011. Available at
    • Healthstore, 2011. FSC Kudzu Capsule. Healthstore.uk.com Accessed 7 January 2011. Available at: http://www.healthstore.uk.com/c43206/kudzu.html.
    • (2011) FSC Kudzu Capsule
  • 60
    • 33645840777 scopus 로고    scopus 로고
    • Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine
    • D.G. Hemmings Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine Naunyn-Schmiedberg's Archives of Pharmacology 382 2006 18 29
    • (2006) Naunyn-Schmiedberg's Archives of Pharmacology , vol.382 , pp. 18-29
    • Hemmings, D.G.1
  • 64
    • 67349101738 scopus 로고    scopus 로고
    • A promising approach for understanding the mechanism of Traditional Chinese Medicine by the aggregation morphology
    • J. Hu, Z. Wu, J. Yan, W. Pang, D. Liang, and X. Xu A promising approach for understanding the mechanism of Traditional Chinese Medicine by the aggregation morphology Journal of Ethnopharmacology 123 2009 267 274
    • (2009) Journal of Ethnopharmacology , vol.123 , pp. 267-274
    • Hu, J.1    Wu, Z.2    Yan, J.3    Pang, W.4    Liang, D.5    Xu, X.6
  • 65
    • 72049109482 scopus 로고    scopus 로고
    • Puerarin inhibits adhesion molecule expression in tnf-alpha-stimulated human endothelial cells via modulation of the nuclear factor kappaB pathway
    • W. Hu, Q. Zhang, X. Yang, Y. Wang, and L. Sun Puerarin inhibits adhesion molecule expression in tnf-alpha-stimulated human endothelial cells via modulation of the nuclear factor kappaB pathway Pharmacology 85 2010 27 35
    • (2010) Pharmacology , vol.85 , pp. 27-35
    • Hu, W.1    Zhang, Q.2    Yang, X.3    Wang, Y.4    Sun, L.5
  • 66
    • 33747781747 scopus 로고    scopus 로고
    • Inflammation in stroke and focal cerebral ischemia
    • DOI 10.1016/j.surneu.2005.12.028, PII S0090301906001017
    • J. Huang, U.M. Upadhyay, and R.J. Tamargo Inflammation in stroke and focal cerebral ischaemia Surgical Neurology 66 2006 232 245 (Pubitemid 44279808)
    • (2006) Surgical Neurology , vol.66 , Issue.3 , pp. 232-245
    • Huang, J.1    Upadhyay, U.M.2    Tamargo, R.J.3
  • 68
    • 78650117385 scopus 로고    scopus 로고
    • IDF International Diabetes Federation Altas. Accessed 20 September 2010. Available at
    • IDF, 2009. Diabetes and Impaired Glucose Tolerance: Global Burden. International Diabetes Federation Altas. Accessed 20 September 2010. Available at: http://www.diabetesatlas.org/content/diabetes-and-impaired-glucose- tolerance.
    • (2009) Diabetes and Impaired Glucose Tolerance: Global Burden
  • 69
    • 79954423900 scopus 로고    scopus 로고
    • IUCN Accessed 20 August 2010. Available at
    • IUCN, 2005. Global Invasive Species Database: Puerarin montana var. lobata. Accessed 20 August 2010. Available at: http://www.issg.org/database/ species/ecology.asp?si=81&fr=1&sts=&lang=EN.
    • (2005) Global Invasive Species Database: Puerarin Montana Var. Lobata
  • 70
    • 1542752261 scopus 로고    scopus 로고
    • Recent advances in the development of phytoestrogens and derivatives: An update of the promising perspectives in the prevention of postmenopausal diseases
    • Y. Jacquot, C. Rojas, B. Refouvelt, J.F. Robert, G. Leclercq, and A. Xicluna Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases Mini Reviews in Medicinal Chemistry 3 2003 387 400
    • (2003) Mini Reviews in Medicinal Chemistry , vol.3 , pp. 387-400
    • Jacquot, Y.1    Rojas, C.2    Refouvelt, B.3    Robert, J.F.4    Leclercq, G.5    Xicluna, A.6
  • 71
    • 6344290233 scopus 로고    scopus 로고
    • Characterizing specimens of kudzu and related taxa with RAPD's
    • D.K. Jewett, C.J. Jiang, K.O. Brittin, J.H. Sun, and J. Tang Characterizing specimens of kudzu and related taxa with RAPD's Castanea 68 2003 254 260
    • (2003) Castanea , vol.68 , pp. 254-260
    • Jewett, D.K.1    Jiang, C.J.2    Brittin, K.O.3    Sun, J.H.4    Tang, J.5
  • 72
    • 0344442350 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin
    • DOI 10.1016/j.cellbi.2003.09.007
    • B. Jiang, J.H. Liu, Y.M. Bao, and L.J. An Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin Cell Biology International 27 2003 1025 1031 (Pubitemid 37463535)
    • (2003) Cell Biology International , vol.27 , Issue.12 , pp. 1025-1031
    • Jiang, B.1    Liu, J.H.2    Bao, Y.M.3    An, L.J.4
  • 73
    • 20844446133 scopus 로고    scopus 로고
    • A comparative study on aqueous root extracts of Pueraria thomsonii and Pueraria lobata by antioxidant assay and HPLC fingerprint analysis
    • DOI 10.1016/j.jep.2004.08.029, PII S0378874104004258
    • R.W. Jiang, K.M. Lau, H.M. Lam, W.S. Yam, L.K. Leung, K.L. Choi, M.M. Waye, T.C. Mak, K.S. Woo, and K.P. Fung A comparative study on aqueous root extracts of Pueraria thomsonii and Pueraria lobata by antioxidant assay and HPLC fingerprint analysis Journal of Ethnopharmacology 96 2005 133 138 (Pubitemid 39575042)
    • (2005) Journal of Ethnopharmacology , vol.96 , Issue.1-2 , pp. 133-138
    • Jiang, R.-W.1    Lau, K.-M.2    Lam, H.-M.3    Yam, W.-S.4    Leung, L.-K.5    Choi, K.-L.6    Waye, M.M.Y.7    Mak, T.C.W.8    Woo, K.-S.9    Fung, K.-P.10
  • 74
    • 79954422939 scopus 로고    scopus 로고
    • Therapeutic wisdom in traditional Chinese medicine: A prespective from modern science
    • W.Y. Jiang Therapeutic wisdom in traditional Chinese medicine: a prespective from modern science Discovert Medicine 5 2005 455 461
    • (2005) Discovert Medicine , vol.5 , pp. 455-461
    • Jiang, W.Y.1
  • 75
    • 48849106250 scopus 로고    scopus 로고
    • Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria
    • J.-S. Jin, T. Nishihata, N. Kakiuchi, and M. Hattori Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria Biological & Pharmaceutical Bulletin 31 2008 1621 1625
    • (2008) Biological & Pharmaceutical Bulletin , vol.31 , pp. 1621-1625
    • Jin, J.-S.1    Nishihata, T.2    Kakiuchi, N.3    Hattori, M.4
  • 76
    • 29344443799 scopus 로고    scopus 로고
    • Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isoflavones in murine macrophages
    • DOI 10.1002/mnfr.200500103
    • M. Jun, J. Hong, W.S. Jeong, and C.T. Ho Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isoflavones in murine macrophages Molecular Nutrition & Food Research 49 2005 1154 1159 (Pubitemid 43004348)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.12 , pp. 1154-1159
    • Jun, M.1    Hong, J.2    Jeong, W.-S.3    Ho, C.-T.4
  • 77
    • 15544388564 scopus 로고    scopus 로고
    • Matrix metalloproteinases and diabetic vascular complications
    • DOI 10.1177/000331970505600208
    • N.P. Kadoglou, S.S. Daskalopoulou, D. Perrea, and C.D. Liapis Matrix metalloproteinases and diabetic vascular complications Angiology 56 2005 173 189 (Pubitemid 40404472)
    • (2005) Angiology , vol.56 , Issue.2 , pp. 173-189
    • Kadoglou, N.P.1    Daskalopoulou, S.S.2    Perrea, D.3    Liapis, C.D.4
  • 78
    • 0032007694 scopus 로고    scopus 로고
    • Kudzu root: An ancient Chinese source of modern antidipsotropic agents
    • DOI 10.1016/S0031-9422(97)00723-1, PII S0031942297007231
    • W.M. Keung, and B.L. Vallee Kudzu root: an ancient Chinese source of modern antidipsotropic agents Phytochemistry 47 1998 499 506 (Pubitemid 28051412)
    • (1998) Phytochemistry , vol.47 , Issue.4 , pp. 499-506
    • Keung, W.M.1    Vallee, B.L.2
  • 79
    • 0032814249 scopus 로고    scopus 로고
    • Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships
    • DOI 10.1016/S0006-2952(99)00160-4, PII S0006295299001604
    • H.K. Kim, B.S. Cheon, Y.H. Kim, S.Y. Kim, and H.P. Kim Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships Biochemical Pharmacology 58 1999 759 765 (Pubitemid 29329524)
    • (1999) Biochemical Pharmacology , vol.58 , Issue.5 , pp. 759-765
    • Kim, H.K.1    Cheon, B.S.2    Kim, Y.H.3    Kim, S.Y.4    Kim, H.P.5
  • 80
    • 55049109851 scopus 로고    scopus 로고
    • Puerarol from the roots of Pueraria lobata inhibits the formation of advanced glyceration end products (AGEs) in vitro
    • J.M. Kim, D.S. Jang, Y.M. Lee, Y.S. Kim, and J.S. Kim Puerarol from the roots of Pueraria lobata inhibits the formation of advanced glyceration end products (AGEs) in vitro Natural Product Science 14 2008 192 195
    • (2008) Natural Product Science , vol.14 , pp. 192-195
    • Kim, J.M.1    Jang, D.S.2    Lee, Y.M.3    Kim, Y.S.4    Kim, J.S.5
  • 81
    • 77950033149 scopus 로고    scopus 로고
    • Puerarin supresses AGEs-induced inflammation in mouse mesangial cells: A possible pathway through the induction of heme oxygenase-1 expression
    • K.M. Kim, D.H. Jung, D.S. Jang, Y.S. Kim, J.M. Kim, H.K. Kim, Y. Surh, and J.S. Kim Puerarin supresses AGEs-induced inflammation in mouse mesangial cells: a possible pathway through the induction of heme oxygenase-1 expression Toxicology and Applied Pharmacology 244 2010 106 113
    • (2010) Toxicology and Applied Pharmacology , vol.244 , pp. 106-113
    • Kim, K.M.1    Jung, D.H.2    Jang, D.S.3    Kim, Y.S.4    Kim, J.M.5    Kim, H.K.6    Surh, Y.7    Kim, J.S.8
  • 83
    • 85008119786 scopus 로고
    • Studies on the constituents of Pueraria lobata, III. Isoflavonoids and related compounds in the roots and the voluble stems
    • J.E. Kinjo, J.C. Furusawa, J. Baba, T. Takeshita, M. Yamasaki, and T. Nohara Studies on the constituents of Pueraria lobata, III. Isoflavonoids and related compounds in the roots and the voluble stems Chemical & Pharmaceutical Bulletin 35 1987 4846 4850
    • (1987) Chemical & Pharmaceutical Bulletin , vol.35 , pp. 4846-4850
    • Kinjo, J.E.1    Furusawa, J.C.2    Baba, J.3    Takeshita, T.4    Yamasaki, M.5    Nohara, T.6
  • 85
    • 0642281196 scopus 로고    scopus 로고
    • The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells
    • J.S. Lee, J. Mamo, N. Ho, and S. Pal The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells BMC Complementary & Alternative Medicine 2 2002 16
    • (2002) BMC Complementary & Alternative Medicine , vol.2 , pp. 16
    • Lee, J.S.1    Mamo, J.2    Ho, N.3    Pal, S.4
  • 86
    • 0035172712 scopus 로고    scopus 로고
    • Tectorigenin, an isoflavone of Pueraria thunbergiana BENTH., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells
    • DOI 10.1248/bpb.24.1117
    • K.T. Lee, I.C. Sohn, Y.K. Kim, J.H. Choi, J.W. Choi, H.J. Park, and K. Miyamoto Tectorigenin, an isoflavone of Pueraria thunbergiana, induces differentiation and apoptosis on human promyelocytic leukemia cells Biological & Pharmaceutical Bulletin 24 2001 1117 1121 (Pubitemid 33049070)
    • (2001) Biological and Pharmaceutical Bulletin , vol.24 , Issue.10 , pp. 1117-1121
    • Lee, K.-T.1    Sohn, I.-C.2    Kim, Y.-K.3    Choi, J.-H.4    Choi, J.-W.5    Park, H.-J.6    Itoh, Y.7    Miyamoto, K.-I.8
  • 88
    • 67650854594 scopus 로고    scopus 로고
    • Effect of puerarin on the expression of extracellular matrix in rats with stroptozotocin-induced diabetic nephropathy
    • Q. Li, Y. Xiao, H. Gong, D. Shen, F. Zhu, Q. Wu, H. Chen, and H. Zhong Effect of puerarin on the expression of extracellular matrix in rats with stroptozotocin-induced diabetic nephropathy The National Medical Journal of India 22 2009 9 12
    • (2009) The National Medical Journal of India , vol.22 , pp. 9-12
    • Li, Q.1    Xiao, Y.2    Gong, H.3    Shen, D.4    Zhu, F.5    Wu, Q.6    Chen, H.7    Zhong, H.8
  • 89
    • 77956088595 scopus 로고    scopus 로고
    • Study of regulation of puerarin on blood P-selectin and the expression of aorta VCAM mRNA in diabetes
    • Q. Li, X. Zhang, F. Zhu, and Z. Zhang Study of regulation of puerarin on blood P-selectin and the expression of aorta VCAM mRNA in diabetes Wei Sheng Yan Jiu/Journal of Hygiene Research 36 2007 581 583 (in Chinese)
    • (2007) Wei Sheng Yan Jiu/Journal of Hygiene Research , vol.36 , pp. 581-583
    • Li, Q.1    Zhang, X.2    Zhu, F.3    Zhang, Z.4
  • 91
    • 33646490262 scopus 로고    scopus 로고
    • Pharmacokinetic, tissue distribution, and excretion of puerarin and puerarin-phospholipid complex in rats
    • Y. Li, W.S. Pan, S.L. Chen, H.X. Xu, D.J. Yang, and A.S.C. Chan Pharmacokinetic, tissue distribution, and excretion of puerarin and puerarin-phospholipid complex in rats Drug Development & Industrial Pharmacy 32 2006 413 422
    • (2006) Drug Development & Industrial Pharmacy , vol.32 , pp. 413-422
    • Li, Y.1    Pan, W.S.2    Chen, S.L.3    Xu, H.X.4    Yang, D.J.5    Chan, A.S.C.6
  • 93
    • 30344467835 scopus 로고    scopus 로고
    • Determination of 12 pueraria components by high-performance liquid chromatography-mass spectrometry
    • C.C. Lin, C.I. Wu, and S.J. Sheu Determination of 12 pueraria components by high-performance liquid chromatography-mass spectrometry Journal of Separation Science 28 2005 1785 1795
    • (2005) Journal of Separation Science , vol.28 , pp. 1785-1795
    • Lin, C.C.1    Wu, C.I.2    Sheu, S.J.3
  • 94
    • 79954418788 scopus 로고    scopus 로고
    • The pharmacology and toxicity of puerarin: A literature review
    • F.Q. Liu The pharmacology and toxicity of puerarin: a literature review China New Medicine 3 2004 (in Chinese)
    • (2004) China New Medicine , vol.3
    • Liu, F.Q.1
  • 95
    • 79954417311 scopus 로고    scopus 로고
    • Clinical observation of puerarin decoction in treating hyperlipoproteinaemia
    • L.H. Liu, F.Q. Liu, and H. Tian Clinical observation of puerarin decoction in treating hyperlipoproteinaemia Hebei Journal of Traditional Chinese Medicine 30 2008 804 805
    • (2008) Hebei Journal of Traditional Chinese Medicine , vol.30 , pp. 804-805
    • Liu, L.H.1    Liu, F.Q.2    Tian, H.3
  • 96
    • 0642305219 scopus 로고    scopus 로고
    • Restrictive Effect of Puerarin on Myocardial Infarct Area in Dogs and Its Possible Mechanism
    • Q. Liu, Z. Lu, and L. Wang Restrictive effect of puerarin on myocardial infarct area in dogs and its possible mechanism Journal of Tongji Medical University 20 2000 43 45 (Pubitemid 33210417)
    • (2000) Journal of Tongji Medical University , vol.20 , Issue.1 , pp. 43-45
    • Liu, Q.1    Lu, Z.2    Wang, L.3
  • 97
    • 33845526619 scopus 로고    scopus 로고
    • Pharmacokinetics of puerarin and ginsenoside Rg1 of CBN injection and the relation with platelet aggregation in rats
    • DOI 10.1142/S0192415X06004508, PII S0192415X06004508
    • R. Liu, D. Xing, H. Wu, and L. Du Pharmacokinetics of puerarin and ginsenoside Rg1 of CBN injection and the relation with platelet aggregation in rats The American Journal of Chinese Medicine 34 2006 1037 1045 (Pubitemid 44921248)
    • (2006) American Journal of Chinese Medicine , vol.34 , Issue.6 , pp. 1037-1045
    • Liu, R.1    Xing, D.2    Lu, H.3    Wu, H.4    Du, L.5
  • 100
    • 79954425701 scopus 로고    scopus 로고
    • Effect of different processing methods on the content of puerarin in gegen
    • Z.G. Long, and X.Y. Zhao Effect of different processing methods on the content of puerarin in gegen Chinese Journal of Hospital Pharmacy 22 2002 511 512 (in Chinese)
    • (2002) Chinese Journal of Hospital Pharmacy , vol.22 , pp. 511-512
    • Long, Z.G.1    Zhao, X.Y.2
  • 101
    • 3543098689 scopus 로고    scopus 로고
    • Theory of traditional chinese medicine and therapeutic method of diseases
    • A. Lu, H. Jia, C. Xiao, and Q. Lu Theory of traditional Chinese medicine and therapeutic method of diseases World Journal of Gastroenterology 10 2004 1854 1856 (Pubitemid 39029278)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.13 , pp. 1854-1856
    • Lu, A.-P.1    Jia, H.-W.2    Xiao, C.3    Lu, Q.-P.4
  • 102
    • 79954422475 scopus 로고    scopus 로고
    • Clinical observation on the effect of Gegen Qushi decoction in treating hyperlipideamia
    • X. Lu Clinical observation on the effect of Gegen Qushi decoction in treating hyperlipideamia Chinese Journal of Traditional Medical Science and Technology 11 2004 12 14
    • (2004) Chinese Journal of Traditional Medical Science and Technology , vol.11 , pp. 12-14
    • Lu, X.1
  • 103
    • 0023216855 scopus 로고
    • Puerarin β-adrenergic receptor blocking effect
    • X.R. Lu, E. Gao, L.Z. Xu, H.Z. Li, B. Kang, W.N. Chen, S.M. Chen, and X.S. Chai Puerarin beta-adrenergic receptor blocking effect Chinese Medical Journal 100 1987 25 28 (in Chinese) (Pubitemid 17061607)
    • (1987) Chinese Medical Journal , vol.100 , Issue.1 , pp. 25-28
    • Lu, X.-R.1    Gao, E.2    Xu, L.-Z.3
  • 107
    • 34548814880 scopus 로고    scopus 로고
    • Vasodilation effect of puerarin on abdominal aortic artery in the rat and the underlying mechansim
    • J.J. Ma, H. Ma, Y.M. Wang, H.M. Li, and J.M. Pei Vasodilation effect of puerarin on abdominal aortic artery in the rat and the underlying mechansim Journal of the Fourth Military Medical University 24 2003 2231 2234 (in Chinese)
    • (2003) Journal of the Fourth Military Medical University , vol.24 , pp. 2231-2234
    • Ma, J.J.1    Ma, H.2    Wang, Y.M.3    Li, H.M.4    Pei, J.M.5
  • 109
    • 4444222221 scopus 로고    scopus 로고
    • Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    • DOI 10.1161/01.CIR.0000140677.20606.0E
    • S. Malik, N.D. Wong, S.S. Franklin, T.V. Kamath, G.J. L'Italien, J.R. Pio, and G.R. Williams Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults Circulation 110 2004 1245 1250 (Pubitemid 39202340)
    • (2004) Circulation , vol.110 , Issue.10 , pp. 1245-1250
    • Malik, S.1    Wong, N.D.2    Franklin, S.S.3    Kamath, T.V.4    L'Italien, G.J.5    Pio, J.R.6    Williams, G.R.7
  • 112
    • 58549095630 scopus 로고    scopus 로고
    • Puerarin protects against high glucose-induced acute vascular dysfunction: Role of heme oxygenase-1 in rat thoracic aorta
    • X.H. Meng, C. Ni, L. Zhu, Y.L. Shen, L.L. Wang, and Y.Y. Chen Puerarin protects against high glucose-induced acute vascular dysfunction: role of heme oxygenase-1 in rat thoracic aorta Vascular Pharmacology 50 2009 110 115
    • (2009) Vascular Pharmacology , vol.50 , pp. 110-115
    • Meng, X.H.1    Ni, C.2    Zhu, L.3    Shen, Y.L.4    Wang, L.L.5    Chen, Y.Y.6
  • 113
    • 5444233626 scopus 로고    scopus 로고
    • Pathophysiology of stroke: Lessons from animal models
    • DOI 10.1023/B:MEBR.0000043966.46964.e6
    • P. Mergenthaler, U. Dirnagl, and A. Meisel Pathophysiology of stroke: lessons from animal models Metabolic Brain Disease 19 2004 151 167 (Pubitemid 39361178)
    • (2004) Metabolic Brain Disease , vol.19 , Issue.3-4 , pp. 151-167
    • Mergenthaler, P.1    Dirnagl, U.2    Meisel, A.3
  • 115
    • 35348969777 scopus 로고    scopus 로고
    • Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana
    • S.W. Min, and D.H. Kim Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana Biological & Pharmaceutical Bulletin 30 2007 1965 1968
    • (2007) Biological & Pharmaceutical Bulletin , vol.30 , pp. 1965-1968
    • Min, S.W.1    Kim, D.H.2
  • 116
    • 85008294316 scopus 로고
    • Volatile flavor components of Puerariae Radix (Pueraria lobata Ohwi)
    • M. Miyazawa, and H. Kameoka Volatile flavor components of Puerariae Radix (Pueraria lobata Ohwi) Agricultural and Biology Chemistry 52 1988 1053 1055
    • (1988) Agricultural and Biology Chemistry , vol.52 , pp. 1053-1055
    • Miyazawa, M.1    Kameoka, H.2
  • 117
    • 85004302426 scopus 로고
    • Studies on the constituents of Japanese and Chinese crude drugs IV. on the Constituents of Pueraria Root (2)
    • T. Murakami, Y. Nishikawa, and T. Ando Studies on the constituents of Japanese and Chinese crude drugs IV. On the Constituents of Pueraria Root (2) Chemical & Pharmaceutical Bulletin 8 1960 688 691
    • (1960) Chemical & Pharmaceutical Bulletin , vol.8 , pp. 688-691
    • Murakami, T.1    Nishikawa, Y.2    Ando, T.3
  • 119
    • 49449106453 scopus 로고    scopus 로고
    • Molecular mechanisms of apoptosis in cerebral ischaemia: Multiple neuroprotective opportunities
    • V.P. Nakka, A. Gusain, S.L. Mehta, and R. Raghubir Molecular mechanisms of apoptosis in cerebral ischaemia: multiple neuroprotective opportunities Molecular Neurobiology 37 2008 7 38
    • (2008) Molecular Neurobiology , vol.37 , pp. 7-38
    • Nakka, V.P.1    Gusain, A.2    Mehta, S.L.3    Raghubir, R.4
  • 122
    • 79954422872 scopus 로고    scopus 로고
    • NWO Noxious Weeds Office, NSW, Australia
    • NWO, 2008. Weed List 2008. Noxious Weeds Office, NSW, Australia.
    • (2008) Weed List 2008
  • 124
    • 56049090343 scopus 로고    scopus 로고
    • Protecting mechanism of puerarin on the brain neurocyte of rat in acute local ischaemia brain injury and local cerebral ischaemia-reperfusion injury
    • H. Pan, and L. Gao Protecting mechanism of puerarin on the brain neurocyte of rat in acute local ischaemia brain injury and local cerebral ischaemia-reperfusion injury The Pharmaceutical Society of Japan 128 2008 1689 1698
    • (2008) The Pharmaceutical Society of Japan , vol.128 , pp. 1689-1698
    • Pan, H.1    Gao, L.2
  • 126
    • 0036599579 scopus 로고    scopus 로고
    • Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana
    • K.Y. Park, G.O. Jung, J. Choi, K.T. Lee, and H.J. Park Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana Archives of Pharmacal Research 25 2002 320 324 (Pubitemid 43093312)
    • (2002) Archives of Pharmacal Research , vol.25 , Issue.3 , pp. 320-324
    • Park, K.-Y.1    Jung, G.-O.2    Choi, J.3    Lee, K.-T.4    Park, H.-J.5
  • 127
    • 33750625101 scopus 로고    scopus 로고
    • Pharmacokinetic profile of the isoflavone puerarin after acute and repeated administration of a novel kudzu extract to human volunteers
    • DOI 10.1089/acm.2006.12.543
    • D.M. Penetar, C.J. Teter, Z. Ma, M. Tracy, D.Y.W. Lee, and S.E. Lukas Pharmacokinetic profile of the isoflavone puerarin after acute and repeated administration of a novel kudzu extract to human volunteers Journal of Alternative & Complementary Medicine 12 2006 543 548 (Pubitemid 44689677)
    • (2006) Journal of Alternative and Complementary Medicine , vol.12 , Issue.6 , pp. 543-548
    • Penetar, D.M.1    Teter, C.J.2    Ma, Z.3    Tracy, M.4    Lee, D.Y.-W.5    Lukas, S.E.6
  • 131
    • 33750027681 scopus 로고    scopus 로고
    • Cytochrome P450s and cholesterol homeostasis
    • DOI 10.1016/j.pharmthera.2006.05.014, PII S0163725806001161
    • I.A. Pikuleva Cytochrome P450s and cholesterol homeostasis Pharmacology & Therapeutics 112 2006 761 773 (Pubitemid 44573496)
    • (2006) Pharmacology and Therapeutics , vol.112 , Issue.3 , pp. 761-773
    • Pikuleva, I.A.1
  • 136
    • 0037817324 scopus 로고    scopus 로고
    • Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry
    • J.K. Prasain, K. Jones, M. Kirk, L. Wilson, M. Smith-Johnson, C. Weaver, and S. Barnes Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry Journal of Agricultural & Food Chemistry 51 2003 4213 4218
    • (2003) Journal of Agricultural & Food Chemistry , vol.51 , pp. 4213-4218
    • Prasain, J.K.1    Jones, K.2    Kirk, M.3    Wilson, L.4    Smith-Johnson, M.5    Weaver, C.6    Barnes, S.7
  • 137
    • 58149352381 scopus 로고    scopus 로고
    • Tissue distribution of puerarin and its conjugated metabolites in rats assessed by liquid chromatography-tandem mass spectrometry
    • J.K. Prasain, N. Peng, R. Moore, A. Arabshahi, S. Barnes, and J.M. Wyss Tissue distribution of puerarin and its conjugated metabolites in rats assessed by liquid chromatography-tandem mass spectrometry Phytomedicine 16 2009 65 71
    • (2009) Phytomedicine , vol.16 , pp. 65-71
    • Prasain, J.K.1    Peng, N.2    Moore, R.3    Arabshahi, A.4    Barnes, S.5    Wyss, J.M.6
  • 138
    • 33846422731 scopus 로고    scopus 로고
    • Identification of isoflavone glycosides in pueraria lobata cultures by tandem mass spectrometry
    • DOI 10.1002/pca.951
    • J.K. Prasain, A. Reppert, K. Jones, D.R. Moore II, S. Barnes, and M.A. Lila Identification of isoflavone glycosides in Pueraria lobata cultures by tandem mass spectrometry Phytochemical Analysis 18 2007 50 59 (Pubitemid 46138677)
    • (2007) Phytochemical Analysis , vol.18 , Issue.1 , pp. 50-59
    • Prasain, J.K.1    Reppert, A.2    Jones, K.3    Moore II, D.R.4    Barnes, S.5    Lila, M.A.6
  • 139
    • 0021908716 scopus 로고
    • Naturally occurring oestrogens in foods - A review
    • K.R. Price, and G.R. Fenwick Naturally occuring estrogens in foods - a review Food Additives & Contaimnants 2 1985 73 106 (Pubitemid 15118162)
    • (1985) Food Additives and Contaminants , vol.2 , Issue.2 , pp. 73-106
    • Price, K.R.1    Fenwick, G.R.2
  • 140
    • 0032864998 scopus 로고    scopus 로고
    • Blocking effect of Puerarin on calcium channel in isolated guinea pig ventricular myocytes
    • Y. Qian, Z. Li, L. Huang, X. Han, J. Sun, H. Zhou, and Z. Liu Blocking effect of Puerarin on calcium channel in isolated guinea pig ventricular myocytes Chinese Medical Journal 112 1999 787 789 (Pubitemid 29477598)
    • (1999) Chinese Medical Journal , vol.112 , Issue.9 , pp. 787-789
    • Qian, Y.1    Li, Z.2    Huang, L.3    Han, X.4    Sun, J.5    Zhou, H.6    Liu, Z.7
  • 141
    • 52949142183 scopus 로고    scopus 로고
    • Role of potassium currents in cardiac arrhythmias
    • U. Ravens, and E. Cerbai Role of potassium currents in cardiac arrhythmias Europace 10 2008 1133 1137
    • (2008) Europace , vol.10 , pp. 1133-1137
    • Ravens, U.1    Cerbai, E.2
  • 142
    • 79954421831 scopus 로고    scopus 로고
    • Chapter 5: Chemical constituents of Pueraria plants: Identification and methods of analysis
    • H. Rong, D.D. Keukeleire, and L.D. Cooman Chapter 5: Chemical constituents of Pueraria plants: identification and methods of analysis W.M. Keung, Pueraria: The Genus Pueraria 2002 CRC Press USA 23 25
    • (2002) Pueraria: The Genus Pueraria , pp. 23-25
    • Rong, H.1    Keukeleire, D.D.2    Cooman, L.D.3
  • 143
    • 0031754945 scopus 로고    scopus 로고
    • Identification of isoflavones in the roots of Pueraria lobata
    • DOI 10.1055/s-2006-957534
    • H. Rong, J.F. Stevens, M.L. Deinzer, L.D. Cooman, and D.D. Kueukeleire Identification of isoflavones in the roots of Pueraria lobata Planta Medica 64 1998 620 627 (Pubitemid 28481474)
    • (1998) Planta Medica , vol.64 , Issue.7 , pp. 620-627
    • Rong, H.1    Stevens, J.F.2    Deinzer, M.L.3    De Cooman, L.4    De Keukeleire, D.5
  • 145
    • 4344559467 scopus 로고    scopus 로고
    • The glucose transporter families SGLT and GLUT: Molecular basis of normal and aberrant function
    • A. Scheepers, H.G. Joost, and A. Schurmann The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function Journal of Parenteral & Enteral Nutrition 28 2004 364 371 (Pubitemid 39121460)
    • (2004) Journal of Parenteral and Enteral Nutrition , vol.28 , Issue.5 , pp. 364-371
    • Scheepers, A.1    Joost, H.-G.2    Schurmann, A.3
  • 146
    • 79954417697 scopus 로고    scopus 로고
    • SDA State Drug Administration Accessed 7 January 2011. Available at (inChinese
    • SDA, 2002. Introduction to Puerarin glucose injection. State Drug Administration Accessed 7 January 2011. Available at: http://www.sda.gov.cn/hy5/ 028.htm (in Chinese).
    • (2002) Introduction to Puerarin Glucose Injection
  • 147
    • 15444371165 scopus 로고    scopus 로고
    • A dominant negative human peroxisome proliferator-activated receptor (PPAR)α is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms
    • DOI 10.1210/en.2004-1405
    • R.K. Semple, A. Meirhaeghe, A.J. Vidal-Puig, J.W. Schwabe, D. Wiggins, G.F. Gibbons, M. Gurnell, V.K. Chatterjee, and S. O'Rahilly A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms Endocrinology 146 2005 1871 1882 (Pubitemid 40396897)
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1871-1882
    • Semple, R.K.1    Meirhaeghe, A.2    Vidal-Puig, A.J.3    Schwabe, J.W.R.4    Wiggins, D.5    Gibbons, G.F.6    Gurnell, M.7    Chatterjee, V.K.K.8    O'Rahilly, S.9
  • 148
    • 70350348348 scopus 로고    scopus 로고
    • Effects of puerarin on receptor for advanced glycation end products in nephridial tissue of streptozotocin-induced diabetic rats
    • J.G. Shen, M.F. Yao, X.C. Chen, Y.F. Feng, Y.H. Ye, and Z.H. Tong Effects of puerarin on receptor for advanced glycation end products in nephridial tissue of streptozotocin-induced diabetic rats Molecular Biology Reports 36 2009 2229 2233
    • (2009) Molecular Biology Reports , vol.36 , pp. 2229-2233
    • Shen, J.G.1    Yao, M.F.2    Chen, X.C.3    Feng, Y.F.4    Ye, Y.H.5    Tong, Z.H.6
  • 150
    • 33744944776 scopus 로고    scopus 로고
    • Estrogenic effect of main components kakkalide and tectoridin of puerariae flos and their metabolites
    • DOI 10.1248/bpb.29.1202
    • J.E. Shin, E.A. Bae, Y.C. Lee, J.Y. Ma, and D.H. Kim Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites Biological & Pharmaceutical Bulletin 29 2006 1202 1206 (Pubitemid 43845483)
    • (2006) Biological and Pharmaceutical Bulletin , vol.29 , Issue.6 , pp. 1202-1206
    • Shin, J.-E.1    Bae, E.-A.2    Lee, Y.C.3    Ma, J.-Y.4    Kim, D.-H.5
  • 152
    • 24344491543 scopus 로고    scopus 로고
    • Effects of puerarin on plasma membrane GLUT4 content in skeletal muscle from insulin-resistant Sprague-Dawley rats under insulin stimulation
    • C.Y. Song, and H.M. Bi Effects of puerarin on plasma membrane GLUT4 content in skeletal muscle from insulin-resistant Sprague-Dawley rats under insulin stimulation Zhongguo Zhong Yao Za Zhi/China Journal of Chinese Materia Medica 29 2004 172 175 (in Chinese)
    • (2004) Zhongguo Zhong Yao Za Zhi/China Journal of Chinese Materia Medica , vol.29 , pp. 172-175
    • Song, C.Y.1    Bi, H.M.2
  • 153
    • 0023804694 scopus 로고
    • Effects of puerarin on blood pressure and plasma renin activity in spontaneously hypertensive rats
    • X.P. Song, P.P. Chen, and X.S. Chai Effects of puerarin on blood pressure and plasma renin activity in spontaneously hypertensive rats Acta Pharmacologica Sinica 9 1988 55 58 (in Chinese)
    • (1988) Acta Pharmacologica Sinica , vol.9 , pp. 55-58
    • Song, X.P.1    Chen, P.P.2    Chai, X.S.3
  • 154
    • 63049117088 scopus 로고    scopus 로고
    • Interactions between advanced glycation end-products (AGE) and their receptors in the development and progression of diabetic nephropathy - Are these receptors valid therapeutic targets
    • K.C. Sourris, and J.M. Forbes Interactions between advanced glycation end-products (AGE) and their receptors in the development and progression of diabetic nephropathy - are these receptors valid therapeutic targets Current Drug Targets 10 2009 42 50
    • (2009) Current Drug Targets , vol.10 , pp. 42-50
    • Sourris, K.C.1    Forbes, J.M.2
  • 155
    • 6344289735 scopus 로고
    • King Kong Kudzu, menace to the south
    • L. Stevens King Kong Kudzu, menace to the south Smithsonian 7 1976 93 98
    • (1976) Smithsonian , vol.7 , pp. 93-98
    • Stevens, L.1
  • 156
    • 27644570233 scopus 로고    scopus 로고
    • Genetic diversity of Pueraria lobata (kudzu) and closely related taxa as revealed by inter-simple sequence repeat analysis
    • DOI 10.1111/j.1365-3180.2005.00462.x
    • J.H. Sun, Z. Li, D.K. Jewett, K.O. Brittin, W.H. Ye, and X. Ge Genetic diversity of Pueraria lobata (kudzu) and closely related taxa as revealed by inter-simple sequence repeat analysis Weed Research 45 2005 255 260 (Pubitemid 41576908)
    • (2005) Weed Research , vol.45 , Issue.4 , pp. 255-260
    • Sun, J.H.1    Li, Z.-C.2    Jewett, D.K.3    Britton, K.O.4    Ye, W.H.5    Ge, X.-J.6
  • 157
    • 34548842533 scopus 로고    scopus 로고
    • Activation of large-conductance calcium-activated potassium channels by puerarin: The underlying mechanism of puerarin-mediated vasodilation
    • DOI 10.1124/jpet.107.125567
    • X.H. Sun, J.P. Ding, H. Li, N. Pan, L. Gan, X.L. Yang, and H.B. Xu Activation of large-conductance calcium-activated potassium channels by puerarin: the underlying mechanism of puerarin-mediated vasodilation Journal of Pharmacology & Experimental Therapeutics 323 2007 391 397 (Pubitemid 47443248)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.323 , Issue.1 , pp. 391-397
    • Sun, X.-H.1    Ding, J.-P.2    Li, H.3    Pan, N.4    Gan, L.5    Yang, X.-L.6    Xu, H.-B.7
  • 158
    • 33846085648 scopus 로고    scopus 로고
    • Molecular authentication of Radix Puerariae Lobatae and Radix Puerariae Thomsonii by ITS and 5S rRNA spacer sequencing
    • DOI 10.1248/bpb.30.173
    • Y. Sun, P. Shaw, and K.P. Fung Molecular authentication of Radix Puerariae Lobatae and Radix Puerariae Thomsonii by ITS and 5s rRNA spacer sequencing Biological & Pharmaceutical Bulletin 30 2006 173 175 (Pubitemid 46066341)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.1 , pp. 173-175
    • Sun, Y.1    Shaw, P.-C.2    Fung, K.-P.3
  • 161
    • 0036371285 scopus 로고    scopus 로고
    • Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus
    • D. Suzuki, M. Yagame, Y. Kim, H. Sakai, and M. Mauer Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus Nephron 92 2002 564 572
    • (2002) Nephron , vol.92 , pp. 564-572
    • Suzuki, D.1    Yagame, M.2    Kim, Y.3    Sakai, H.4    Mauer, M.5
  • 162
    • 0039593399 scopus 로고
    • Zero to thirty mile-a-minute seedlings
    • P. Tabor, and A.W. Susoot Zero to thirty mile-a-minute seedlings Soil Conservation 8 1941 61 65
    • (1941) Soil Conservation , vol.8 , pp. 61-65
    • Tabor, P.1    Susoot, A.W.2
  • 163
  • 166
    • 79954422672 scopus 로고    scopus 로고
    • TGA Accessed 7 January 2011. Available at
    • TGA, 2011. Pueraria lobata. eBS Australian Register of Therapeutic Goods Medicine. Accessed 7 January 2011. Available at: http://www.ebs.tga.gov.au/ebs/ ANZTPAR/PublicWeb.nsf/publicSearch?openAgent&id=AI∼ pueraria%20lobata∼0∼cuMedicines?OpenView.
    • (2011) Pueraria Lobata. EBS Australian Register of Therapeutic Goods Medicine
  • 171
    • 40949149709 scopus 로고    scopus 로고
    • Chapter 1: Pueraria: Botanical characteristics
    • L.J.G. Van der Maesen Chapter 1: Pueraria: botanical characteristics W.M. Keung, Pueraria: The Genus Pueraria 2002 CRC Press USA 15
    • (2002) Pueraria: The Genus Pueraria , pp. 15
    • Van Der Maesen, L.J.G.1
  • 173
    • 84918103862 scopus 로고
    • Isoflavon- and Saponin-glucosides in Soja hispida
    • E. Walz Isoflavon- and Saponin-glucosides in Soja hispida Justus Liebigs Annalen der Chemie 498 1931 118 155
    • (1931) Justus Liebigs Annalen der Chemie , vol.498 , pp. 118-155
    • Walz, E.1
  • 178
    • 27644573085 scopus 로고    scopus 로고
    • WHO World Health Organization. Accessed 20 Spetember 2010. Available at
    • WHO, 2009. Cardiovascular diseases. World Health Organization. Accessed 20 Spetember 2010. Available at: http://www.who.int/mediacentre/factsheets/ fs317/en/index.html.
    • (2009) Cardiovascular Diseases
  • 179
    • 34249802628 scopus 로고    scopus 로고
    • Meta-analysis of traditional Chinese patent medicine for ischemic stroke
    • DOI 10.1161/STROKEAHA.106.473165, PII 0000767020070600000063
    • Wu, B., Liu, M., Liu, H., Li, W., Tan, S., Zhang, S., Fang, Y., 2007. Meta-analysis of traditional Chinese patent medicine for ischaemic stroke. Stroke 38, 1973-1979. (Pubitemid 46847279)
    • (2007) Stroke , vol.38 , Issue.6 , pp. 1973-1979
    • Wu, B.1    Liu, M.2    Liu, H.3    Li, W.4    Tan, S.5    Zhang, S.6    Fang, Y.7
  • 181
    • 60349124556 scopus 로고    scopus 로고
    • Understanding the traditional aspect of Chinese medicine in order to achieve meaningful quality control of Chinese materia medica
    • P.-S. Xie, and A.Y. Leung Understanding the traditional aspect of Chinese medicine in order to achieve meaningful quality control of Chinese materia medica Journal of Chromatography A 1216 2009 1933 1940
    • (2009) Journal of Chromatography A , vol.1216 , pp. 1933-1940
    • Xie, P.-S.1    Leung, A.Y.2
  • 182
    • 77955654995 scopus 로고    scopus 로고
    • Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ehtanol-induced liver stetosis in mice
    • Y. Xiong, Y. Yang, J. Yang, H. Chai, Y. Li, J. Yang, Z. Jia, and Z. Wang Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ehtanol-induced liver stetosis in mice Toxicology 276 2010 64 72
    • (2010) Toxicology , vol.276 , pp. 64-72
    • Xiong, Y.1    Yang, Y.2    Yang, J.3    Chai, H.4    Li, Y.5    Yang, J.6    Jia, Z.7    Wang, Z.8
  • 183
    • 79954419570 scopus 로고    scopus 로고
    • Clinical research of Gegen Qinlian combined with wuling powder in treating 58 cases of acute cerebral infarction
    • J. Xu, and D. Wu Clinical research of Gegen Qinlian combined with wuling powder in treating 58 cases of acute cerebral infarction Fujian Journal of traditional Chinese Medicine 40 2009 17 18
    • (2009) Fujian Journal of Traditional Chinese Medicine , vol.40 , pp. 17-18
    • Xu, J.1    Wu, D.2
  • 184
    • 26444471844 scopus 로고    scopus 로고
    • The study of anti-metabolic syndrome effect of puerarin in vitro
    • DOI 10.1016/j.lfs.2005.03.036, PII S0024320505005837
    • M.E. Xu, S.Z. Xiao, Y.H. Sun, X.X. Zheng, Y. Ou-Yang, and C. Guan The study of anti-metabolic syndrome effect of puerarin in vitro Life Sciences 77 2005 3183 3196 (Pubitemid 41433319)
    • (2005) Life Sciences , vol.77 , Issue.25 , pp. 3183-3196
    • Xu, M.-E.1    Xiao, S.-Z.2    Sun, Y.-H.3    Zheng, X.-X.4    Ou-Yang, Y.5    Guan, C.6
  • 185
    • 23644460137 scopus 로고    scopus 로고
    • The neuroprotection of puerarin against cerebral ischemia is associated with the prevention of apoptosis in rats
    • DOI 10.1055/s-2005-871261
    • X. Xu, S. Zhang, L. Zhang, W. Yan, and X. Zheng The Neuroprotection of puerarin against cerebral ischaemia is associated with the prevention of apoptosis in rats Planta Medica 71 2005 585 591 (Pubitemid 41133065)
    • (2005) Planta Medica , vol.71 , Issue.7 , pp. 585-591
    • Xu, X.1    Zhang, S.2    Zhang, L.3    Yan, W.4    Zheng, X.5
  • 186
    • 34548397110 scopus 로고    scopus 로고
    • Potential involvement of calcium and nitric oxide in protective effects of puerarin on oxygen-glucose deprivation in cultured hippocampal neurons
    • DOI 10.1016/j.jep.2007.06.012, PII S0378874107003091
    • X. Xu, and X. Zheng Potential involvement of calcium and nitric oxide in protective effects of puerarin on oxygen-glucose deprivation in cultured hippocampal neurons Journal of Ethnopharmacology 113 2007 421 426 (Pubitemid 47361557)
    • (2007) Journal of Ethnopharmacology , vol.113 , Issue.3 , pp. 421-426
    • Xu, X.1    Zheng, X.2
  • 187
    • 34548815007 scopus 로고    scopus 로고
    • Inhibition of excitatory amino acid efflux contributes to protective effects of puerarin against cerebral ischemia in rats
    • X.H. Xu, X.X. Zheng, Q. Zhou, and H. Li Inhibition of excitatory amino acid efflux contributes to protective effects of puerarin against cerebral ischaemia in rats Biomedical and Environmental Science 20 2007 336 342 (Pubitemid 47441814)
    • (2007) Biomedical and Environmental Sciences , vol.20 , Issue.4 , pp. 336-342
    • Xu, X.-H.1    Zheng, X.-X.2    Zhou, Q.3    Li, H.4
  • 191
    • 23944437936 scopus 로고    scopus 로고
    • Effects of an aqueous extract of Puerariae flos (Thomsonide) on impairment of passive avoidance behavior in mice
    • DOI 10.1016/j.jep.2005.02.034, PII S0378874105002163
    • T. Yamazaki, M. Yaguchi, Y. Nakajima, T. Hosono, Y. Niiho, Y. Hibi, J. Kinjo, and T. Nohara Effects of an aqueous extract of Puerariae flos (Thomsonide) on impairment of passive avoidance behavior in mice Journal of Ethnopharmacology 100 2005 244 248 (Pubitemid 41206618)
    • (2005) Journal of Ethnopharmacology , vol.100 , Issue.3 , pp. 244-248
    • Yamazaki, T.1    Yaguchi, M.2    Nakajima, Y.3    Hosono, T.4    Niiho, Y.5    Hibi, Y.6    Kinjo, J.7    Nohara, T.8
  • 192
    • 3042623798 scopus 로고    scopus 로고
    • The antidepressant effect of ethanol extract of radix puerariae in mice exposed to cerebral ischemia reperfusion
    • DOI 10.1016/j.pbb.2004.04.010, PII S0091305704001157
    • B. Yan, D.Y. Wang, D.M. Xing, Y. Ding, R.F. Wang, F. Lei, and L.J. Du The antidepressant effect of ethanol extract of radix puerariae in mice exposed to cerebral ischaemia reperfusion Pharmacology, Biochemistry & Behavior 78 2004 319 325 (Pubitemid 38829368)
    • (2004) Pharmacology Biochemistry and Behavior , vol.78 , Issue.2 , pp. 319-325
    • Yan, B.1    Wang, D.-Y.2    Xing, D.-M.3    Ding, Y.4    Wang, R.-F.5    Lei, F.6    Du, L.-J.7
  • 193
    • 32544446889 scopus 로고    scopus 로고
    • Determination of puerarin in rat cortex by high-performance liquid chromatography after intravenous administration of Puerariae flavonoids
    • DOI 10.1002/bmc.549
    • B. Yan, W. Wang, L. Zhang, D. Xing, D. Wang, and L. Du Determination of puerarin in rat cortex by high-performance liquid chromatography after intravenous administration of Puerariae flavonoids Biomedical Chromatography 20 2006 180 184 (Pubitemid 43230870)
    • (2006) Biomedical Chromatography , vol.20 , Issue.2 , pp. 180-184
    • Yan, B.1    Wang, W.2    Zhang, L.3    Xing, D.4    Wang, D.5    Du, L.6
  • 194
    • 33745797747 scopus 로고    scopus 로고
    • Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats
    • DOI 10.1016/j.lfs.2006.01.016, PII S0024320506000555
    • L.P. Yan, S.W. Chan, A.S. Chan, S.L. Chen, X.J. Ma, and H.X. Xu Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats Life Sciences 79 2006 324 330 (Pubitemid 44209060)
    • (2006) Life Sciences , vol.79 , Issue.4 , pp. 324-330
    • Yan, L.-P.1    Chan, S.-W.2    Chan, A.S.-C.3    Chen, S.-L.4    Ma, X.-J.5    Xu, H.-X.6
  • 195
    • 64749108685 scopus 로고    scopus 로고
    • Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta
    • L.P. Yan, Y.L. Zhuang, S.W. Chan, S.L. Chen, and G.G. Shi Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta Naunyn Schmiedebergs Archives of Pharmacology 379 2009 587 597
    • (2009) Naunyn Schmiedebergs Archives of Pharmacology , vol.379 , pp. 587-597
    • Yan, L.P.1    Zhuang, Y.L.2    Chan, S.W.3    Chen, S.L.4    Shi, G.G.5
  • 196
    • 60549110804 scopus 로고    scopus 로고
    • Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response
    • S.F. Yan, R. Ramasamy, and A.M. Schmidt Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response Journal of Molecular Medicine 87 2009 235 247
    • (2009) Journal of Molecular Medicine , vol.87 , pp. 235-247
    • Yan, S.F.1    Ramasamy, R.2    Schmidt, A.M.3
  • 197
    • 77954754224 scopus 로고    scopus 로고
    • Puerarin inhibits c-reactive protein expression via supression of nuclear factor κb activation in lipopolysaccharide-induced peripheral blood mononuclear cells of patients with stable angina pectoris
    • X. Yang, W. Hu, Q. Zhang, Y. Wang, and L. Sun Puerarin inhibits c-reactive protein expression via supression of nuclear factor κB activation in lipopolysaccharide-induced peripheral blood mononuclear cells of patients with stable angina pectoris Basic & Clinical Pharmacology & Toxicology 107 2010 637 642
    • (2010) Basic & Clinical Pharmacology & Toxicology , vol.107 , pp. 637-642
    • Yang, X.1    Hu, W.2    Zhang, Q.3    Wang, Y.4    Sun, L.5
  • 198
    • 77953388484 scopus 로고    scopus 로고
    • Effect of puerarin injection on the mRNA expressions of AT1 and ACE2 in spontaneous hypertension rats
    • X.Y. Ye, H. Song, and C.Z. Lu Effect of puerarin injection on the mRNA expressions of AT1 and ACE2 in spontaneous hypertension rats Chinese Journal of Integrated Traditional and Western Medicine 28 2008 824 827
    • (2008) Chinese Journal of Integrated Traditional and Western Medicine , vol.28 , pp. 824-827
    • Ye, X.Y.1    Song, H.2    Lu, C.Z.3
  • 199
    • 33750480231 scopus 로고    scopus 로고
    • Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery
    • DOI 10.1016/j.ejphar.2006.08.078, PII S0014299906009642
    • D.K. Yeung, S.W. Leung, Y.C. Xu, P.M. Vanhoutte, and R.Y. Man Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium- independent relaxation via the cyclic AMP pathway in porcine coronary artery European Journal of Pharmacology 552 2006 105 111 (Pubitemid 44649298)
    • (2006) European Journal of Pharmacology , vol.552 , Issue.1-3 , pp. 105-111
    • Yeung, D.K.Y.1    Leung, S.W.S.2    Xu, Y.C.3    Vanhoutte, P.M.4    Man, R.Y.K.5
  • 200
    • 0019579709 scopus 로고
    • Pharmacological studies on Radix Puerariae V. Effects of puerarin on platelet aggregation and release of 5-HT from platelet
    • Z. Yin, and K. Tseng Pharmacological studies on Radix Puerariae V. Effects of puerarin on platelet aggregation and release of 5-HT from platelet Zhongguo Yi Xue Ke Xue Yuan Xue Bao/Acta Academiae Medicinae Sinicae 3 1981 44 47 (in Chinese)
    • (1981) Zhongguo Yi Xue Ke Xue Yuan Xue Bao/Acta Academiae Medicinae Sinicae , vol.3 , pp. 44-47
    • Yin, Z.1    Tseng, K.2
  • 201
    • 79954421039 scopus 로고    scopus 로고
    • Formulation optimization and bioavailability after oral and nasal administration in rabbits of puerarin-loaded microemulsion
    • Yu, A., Wang, H., Wang, J., Cao, F., Gao, Y., Cui, J., Zhai, G., 2010. Formulation optimization and bioavailability after oral and nasal administration in rabbits of puerarin-loaded microemulsion. Journal of Pharmaceutical Science
    • (2010) Journal of Pharmaceutical Science
    • Yu, A.1    Wang, H.2    Wang, J.3    Cao, F.4    Gao, Y.5    Cui, J.6    Zhai, G.7
  • 202
    • 79954423069 scopus 로고    scopus 로고
    • The clinical research of improve symptom of hypertension with Gegen Tianma Gouteng decoction
    • Q. Yu The clinical research of improve symptom of hypertension with Gegen Tianma Gouteng decoction Guang Ming Journal of traditional Chinese Medicine 22 2007 50 52 (in Chinese)
    • (2007) Guang Ming Journal of Traditional Chinese Medicine , vol.22 , pp. 50-52
    • Yu, Q.1
  • 203
    • 2142694266 scopus 로고    scopus 로고
    • Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function
    • Z. Yu, and G. Zhang Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function Zhong Yao Cai/Journal of Chinese Medicinal Materials 20 1997 468 469 (in Chinese)
    • (1997) Zhong Yao Cai/Journal of Chinese Medicinal Materials , vol.20 , pp. 468-469
    • Yu, Z.1    Zhang, G.2
  • 205
  • 208
  • 209
    • 27744590599 scopus 로고    scopus 로고
    • High-performance liquid chromatography-tandem mass spectrometry for identification of isoflavones and description of the biotransformation of kudzu root
    • DOI 10.1007/s00216-005-0068-8
    • Y. Zhang, Q. Xu, X. Zhang, J. Chen, X. Liang, and A. Kettrup High-performance liquid chromatography-tandem mass spectrometry for identification of isoflavones and description of the biotransformation of kudzu root Analytical & Bioanalytical Chemistry 383 2005 787 796 (Pubitemid 41605821)
    • (2005) Analytical and Bioanalytical Chemistry , vol.383 , Issue.5 , pp. 787-796
    • Zhang, Y.1    Xu, Q.2    Zhang, X.3    Chen, J.4    Liang, X.5    Kettrup, A.6
  • 211
    • 65449162655 scopus 로고    scopus 로고
    • Therapeutic effect of puerarin on non-alcoholic rat fatty liver by improving leptin signal transduction through JAK2/STAT3 pathways
    • P. Zheng, G. Ji, Z. Ma, T. Liu, L. Xin, H. Wu, X. Liang, and J. Liu Therapeutic effect of puerarin on non-alcoholic rat fatty liver by improving leptin signal transduction through JAK2/STAT3 pathways American Journal of Chinese Medicine 37 2009 69 83
    • (2009) American Journal of Chinese Medicine , vol.37 , pp. 69-83
    • Zheng, P.1    Ji, G.2    Ma, Z.3    Liu, T.4    Xin, L.5    Wu, H.6    Liang, X.7    Liu, J.8
  • 214
    • 74149093839 scopus 로고    scopus 로고
    • Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling
    • L.H. Zhu, L. Wang, D. Wang, H. Jiang, Q.Z. Tang, L. Yan, Z.Y. Bian, X.A. Wang, and H. Li Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling Free Radical Biology & Medicine 48 2010 471 482
    • (2010) Free Radical Biology & Medicine , vol.48 , pp. 471-482
    • Zhu, L.H.1    Wang, L.2    Wang, D.3    Jiang, H.4    Tang, Q.Z.5    Yan, L.6    Bian, Z.Y.7    Wang, X.A.8    Li, H.9


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