Protective effect of puerarin on diabetic retinopathy in rats

Molecular Biology Reports

Volumn 36, Issue 5, 2009, Pages 1129-1133

  Teng, Yan ^a   Cui, Hao ^a   Yang, Mingming ^a   Song, Han ^b   Zhang, Qingsheng ^a   Su, Ying ^a   Zheng, Jianqiu ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Heilongjiang Province Hospital   (China)

Author keywords

Diabetic retinopathy; Puerarin; Vascular growth factor

Indexed keywords

ANGIOGENIC FACTOR; BETA ACTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PUERARIN; STREPTOZOCIN; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG MECHANISM; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; MALE; MORPHOLOGY; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES;

ANIMALS; DIABETIC RETINOPATHY; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOFLAVONES; MALE; PROTECTIVE AGENTS; RATS; RATS, WISTAR; RETINA; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS; RATTUS NORVEGICUS;

EID: 63949083987     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-008-9288-2     Document Type: Article

References (19)

1. S Sato T Yamamoto H Yamashita 2006 Diabetic retinopathy-state of arts of diagnosis and treatment Nippon Rinsho Suppl 3 161 168
2. SE Moss R Klein BE Klein 1998 The 14-year incidence of visual loss in a diabetic population Ophthalmology 105 998 1003 10.1016/S0161-6420(98)96025-0
3. MJ Tolentino JW Miller ES Gragoudas FA Jakobiec E Flynn K Chatzistefanou 1996 Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate Ophthalmology 103 1820 1828
4. W Cherdshewasart S Subtang W Dahlan 2007 Major isoflavonoid contents of the phytoestrogen rich-herb Pueraria mirifica in comparison with Pueraria lobata J Pharm Biomed Anal 43 428 434 10.1016/j.jpba.2006.07.013
5. A Kirakosyan PB Kaufman S Warber S Bolling S Chang JA Duke 2003 Quantification of major isoflavonoids and l-canavanine in several organs of Kudzu vine (Pueraria lobata) and in starch samples derived from Kudzu roots Plant Sci 164 883 888 10.1016/S0168-9452(03)00077-3
6. FL Xiong XH Sun L Gan XL Yang HB Xu 2006 Puerarin protects rat pancreatic islets from damage by hydrogen peroxide Eur J Pharmacol 529 1 7 10.1016/j.ejphar.2005.10.024
7. XR Lu E Gao LZ Xu HZ Li B Kang WN Chen 1986 Blocking effect of puerarin on beta-adrenoceptors of isolated organs and the whole animal Acta Pharmacol Sin 7 537 539
8. W Cherdshewasart W Sutjit 2007 Correlation of antioxidant activity of major isoflavonoid contents of the phytoestrogen-rich Pueraria mirifica and Pueraria lobata Phytomedicine 15 38 43 10.1016/j.phymed.2007.07.058
9. MC Guerra E Speroni M Broccoli M Cangini P Pasini A Minghett 2000 Comparison between Chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effect on rat liver CYP-catalyzed drug metabolism Life Sci 67 2997 3006 10.1016/S0024-3205(00)00885- 7
10. E Benlhabib JI Baker DE Keyler AK Singh 2004 Effects of purified puerarin on voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol J Med Food 7 180 186 10.1089/1096620041224102
11. RC Lin S Guthrie CY Xie K Mai DY Lee L Lumeng 1996 Isoflavonoid compounds extracts from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism Alcohol Clin Exp Res 20 659 663 10.1111/j.1530-0277. 1996.tb01668.x
12. WM Keung BL Vallee 1998 Kudzu root: an ancient Chinese source of modern antidipsotropic agents Phytochemistry 47 499 506 10.1016/S0031-9422(97)00723-1
13. FS Chueh CP Chang CC Chio MT Lin 2004 Puerarin acts through brain serotonergic mechanisms to induce thermal effects J Pharmacol Sci 96 420 427 10.1254/jphs.FP0040424
14. B Xuan YH Zhou RL Yang N Li ZD Min GC Chiou 1999 Improvement of ocular blood flow and retinal functions with puerarin analogs J Ocul Pharmacol Ther 15 207 216
15. AP Adamis JW Miller MT Bernal DJ D'Amico J Folkman TK Yeo 1994 Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy Am J Ophthalmol 118 445 450
16. SC Dieudonné EC La Heij RM Diederen AG Kessels AT Liem A Kijlstra 2007 Balance of vascular endothelial growth factor and pigment epithelial growth factor prior to development of proliferative vitreoretinopathy Ophthalmic Res 39 148 154 10.1159/000103234
17. S Zhang S Chen Y Shen D Yang X Liu AC Sun-chi 2006 Puerarin induces angiogenesis in myocardium of rat with myocardial infarction Biol Pharm Bull 29 945 950 10.1248/bpb.29.945
18. JA Forsythe BH Jiang NV Iyer F Agani SW Leung RD Koos 1996 Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Mol Cell Biol 9 4604 4613
19. NS Levy MA Goldberg AP Levy 1997 Sequencing of the human vascular endothelial growth factor (VEGF) 3′ untranslated region (UTR): conservation of five hypoxia-inducible RNA-protein binding sites Biochim Biophys Acta 1352 167 173