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Volumn 87, Issue 3, 2009, Pages 235-247

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response

Author keywords

Complications; Diabetes; Glycation; Receptor

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; CALGRANULIN; GLUCOSE; HIGH MOBILITY GROUP B1 PROTEIN; LIGAND; PROTEIN S 100;

EID: 60549110804     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-009-0439-2     Document Type: Review
Times cited : (207)

References (120)
  • 1
    • 0026650438 scopus 로고
    • Isolation and characterization of binding proteins for advanced glycosylation endproducts from lung tissue which are present on the endothelial cell surface
    • AM Schmidt M Vianna M Gerlach 1992 Isolation and characterization of binding proteins for advanced glycosylation endproducts from lung tissue which are present on the endothelial cell surface J Biol Chem 267 14987 14997
    • (1992) J Biol Chem , vol.267 , pp. 14987-14997
    • Schmidt, A.M.1    Vianna, M.2    Gerlach, M.3
  • 2
    • 26444478269 scopus 로고    scopus 로고
    • Advanced glycation end products and RAGE: A common thread in aging, diabetes, neurodegeneration, and inflammation
    • R Ramasamy SJ Vannucci SS Yan 2005 Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation Glycobiol 15 16R 28R
    • (2005) Glycobiol , vol.15
    • Ramasamy, R.1    Vannucci, S.J.2    Yan, S.S.3
  • 3
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • MA Hofmann S Drury C Fu 1999 RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 97 889 901
    • (1999) Cell , vol.97 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3
  • 4
    • 0028851635 scopus 로고
    • The receptor for advanced glycation endproducts (RAGE) is a cellular binding site for amphoterin: Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system
    • O Hori J Brett T Slattery 1995 The receptor for advanced glycation endproducts (RAGE) is a cellular binding site for amphoterin: mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system J Biol Chem 270 25752 25761
    • (1995) J Biol Chem , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3
  • 5
    • 0034682315 scopus 로고    scopus 로고
    • Blockade of amphoterin/RAGE signalling suppresses tumor growth and metastases
    • A Taguchi DC Blood G del Toro 2000 Blockade of amphoterin/RAGE signalling suppresses tumor growth and metastases Nature 405 354 360
    • (2000) Nature , vol.405 , pp. 354-360
    • Taguchi, A.1    Blood, D.C.2    Del Toro, G.3
  • 6
    • 0013615899 scopus 로고    scopus 로고
    • RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
    • SD Yan X Chen J Fu 1996 RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease Nature 382 685 691
    • (1996) Nature , vol.382 , pp. 685-691
    • Yan, S.D.1    Chen, X.2    Fu, J.3
  • 7
    • 0001358519 scopus 로고    scopus 로고
    • Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis
    • SD Yan H Zhu A Zhu 2000 Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis Nat Med 6 643 651
    • (2000) Nat Med , vol.6 , pp. 643-651
    • Yan, S.D.1    Zhu, H.2    Zhu, A.3
  • 8
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment
    • T Chavakis A Bierhaus N Al-Fakhri 2003 The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment J Exp Med 198 1507 1515
    • (2003) J Exp Med , vol.198 , pp. 1507-1515
    • Chavakis, T.1    Bierhaus, A.2    Al-Fakhri, N.3
  • 9
    • 0027718105 scopus 로고
    • Tissue distribution of the receptor for advanced glycation endproducts (RAGE): Expression in smooth muscle, cardiac myocytes, and neural tissue in addition to the vasculature
    • J Brett AM Schmidt YS Zou 1993 Tissue distribution of the receptor for advanced glycation endproducts (RAGE): expression in smooth muscle, cardiac myocytes, and neural tissue in addition to the vasculature Am J Pathol 143 1699 1712
    • (1993) Am J Pathol , vol.143 , pp. 1699-1712
    • Brett, J.1    Schmidt, A.M.2    Zou, Y.S.3
  • 10
    • 0033615356 scopus 로고    scopus 로고
    • Ne (carboxymethyl)lysine modifications of proteins are ligands for RAGE that activate cell signalling pathways and modulate gene expression
    • T Kislinger C Fu B Huber 1999 Ne (carboxymethyl)lysine modifications of proteins are ligands for RAGE that activate cell signalling pathways and modulate gene expression J Biol Chem 274 31740 31749
    • (1999) J Biol Chem , vol.274 , pp. 31740-31749
    • Kislinger, T.1    Fu, C.2    Huber, B.3
  • 11
    • 0026701935 scopus 로고
    • Nonenzymatic glycosylation of macromolecules. Prospects of pharmacologic modulation
    • Suppl 2
    • M Brownlee 1992 Nonenzymatic glycosylation of macromolecules. Prospects of pharmacologic modulation Diabetes 41 Suppl 2 57 60
    • (1992) Diabetes , vol.41 , pp. 57-60
    • Brownlee, M.1
  • 12
    • 38149078193 scopus 로고    scopus 로고
    • Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in Apo E-/- mice
    • E Harja DX Bu BI Hudson 2008 Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in Apo E-/- mice J Clin Invest 118 183 194
    • (2008) J Clin Invest , vol.118 , pp. 183-194
    • Harja, E.1    Bu, D.X.2    Hudson, B.I.3
  • 13
    • 48249134831 scopus 로고    scopus 로고
    • RAGE and modulation of ischemic injury in the diabetic myocardium
    • LG Bucciarelli R Ananthakrishnan YC Hwang 2008 RAGE and modulation of ischemic injury in the diabetic myocardium Diabetes 57 1941 1951
    • (2008) Diabetes , vol.57 , pp. 1941-1951
    • Bucciarelli, L.G.1    Ananthakrishnan, R.2    Hwang, Y.C.3
  • 14
    • 0034996659 scopus 로고    scopus 로고
    • Activation of NADPH oxidase by AGEs links oxidant stress to altered gene expression via RAGE
    • MP Wautier O Chappey S Corda 2001 Activation of NADPH oxidase by AGEs links oxidant stress to altered gene expression via RAGE Am J Physiol Endocrinol Metab 280 E685 E694
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Wautier, M.P.1    Chappey, O.2    Corda, S.3
  • 15
    • 27544455106 scopus 로고    scopus 로고
    • Advanced glycoxidation end products in chronic diseases-clinical chemistry and genetic background
    • M Kalousova T Zima V Tesar 2005 Advanced glycoxidation end products in chronic diseases-clinical chemistry and genetic background Mut Res 579 37 46
    • (2005) Mut Res , vol.579 , pp. 37-46
    • Kalousova, M.1    Zima, T.2    Tesar, V.3
  • 16
    • 0032893391 scopus 로고    scopus 로고
    • Advanced oxidation protein products as novel molecular basis of oxidative stress in uremia
    • Suppl 1
    • M Witko-Sarsat T Nguyen-Khoa P Jungers 1999 Advanced oxidation protein products as novel molecular basis of oxidative stress in uremia Nephrol Dial Transplant 14 Suppl 1 76 78
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 76-78
    • Witko-Sarsat, M.1    Nguyen-Khoa, T.2    Jungers, P.3
  • 17
    • 0037336908 scopus 로고    scopus 로고
    • Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
    • AA Woods SM Linton MJ Davies 2003 Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques Biochem J 370 729 735
    • (2003) Biochem J , vol.370 , pp. 729-735
    • Woods, A.A.1    Linton, S.M.2    Davies, M.J.3
  • 18
    • 0036231575 scopus 로고    scopus 로고
    • Increased level of advanced oxidation protein products in patients with coronary artery disease
    • H Kaneda J Taguchi K Ogasawara 2002 Increased level of advanced oxidation protein products in patients with coronary artery disease Atherosclerosis 162 221 225
    • (2002) Atherosclerosis , vol.162 , pp. 221-225
    • Kaneda, H.1    Taguchi, J.2    Ogasawara, K.3
  • 19
    • 34948869847 scopus 로고    scopus 로고
    • Dietary AGEs and ALEs and risk to human health by their interaction with the receptor for advanced glycation endproducts (RAGE)-an introduction
    • PJ Thornalley 2007 Dietary AGEs and ALEs and risk to human health by their interaction with the receptor for advanced glycation endproducts (RAGE)-an introduction Mol Nutr Food Res 51 1107 1110
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1107-1110
    • Thornalley, P.J.1
  • 20
    • 34548299920 scopus 로고    scopus 로고
    • Novel inhibitors of glycation and AGE formation
    • S Rahbar 2007 Novel inhibitors of glycation and AGE formation Cell Biochem Biophys 48 147 157
    • (2007) Cell Biochem Biophys , vol.48 , pp. 147-157
    • Rahbar, S.1
  • 21
    • 38349138516 scopus 로고    scopus 로고
    • RAGE: A single receptor for several ligands and different cellular responses: The case of certain S100 proteins
    • R Donato 2007 RAGE: a single receptor for several ligands and different cellular responses: the case of certain S100 proteins Curr Mol Med 7 711 724
    • (2007) Curr Mol Med , vol.7 , pp. 711-724
    • Donato, R.1
  • 22
    • 38349052450 scopus 로고    scopus 로고
    • S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway
    • S Ghavami I Rashedi BM Dattilo 2008 S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway J Leukoc Biol 83 1484 1492
    • (2008) J Leukoc Biol , vol.83 , pp. 1484-1492
    • Ghavami, S.1    Rashedi, I.2    Dattilo, B.M.3
  • 23
    • 53349173233 scopus 로고    scopus 로고
    • RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
    • O Turovskaya D Foell P Sinha 2008 RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis Carcinogenesis 29 2035 2043
    • (2008) Carcinogenesis , vol.29 , pp. 2035-2043
    • Turovskaya, O.1    Foell, D.2    Sinha, P.3
  • 24
    • 34447623162 scopus 로고    scopus 로고
    • RAGE activation by S100P in colon cancer stimulates growth, migration and cell signaling pathways
    • MK Fuentes SS Nigavekar T Arumugam 2007 RAGE activation by S100P in colon cancer stimulates growth, migration and cell signaling pathways Dis Col Rectum 50 1230 1240
    • (2007) Dis Col Rectum , vol.50 , pp. 1230-1240
    • Fuentes, M.K.1    Nigavekar, S.S.2    Arumugam, T.3
  • 25
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • P Scaffidi T Misteli ME Bianchi 2002 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 418 191 195
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 26
    • 34249812086 scopus 로고    scopus 로고
    • Masquerader: High mobility group box-1 and cancer
    • JE Ellerman CK Brown M de Vera 2007 Masquerader: high mobility group box-1 and cancer Clin Cancer Res 13 2836 2848
    • (2007) Clin Cancer Res , vol.13 , pp. 2836-2848
    • Ellerman, J.E.1    Brown, C.K.2    De Vera, M.3
  • 27
    • 33845649733 scopus 로고    scopus 로고
    • Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein
    • A Porto R Palumbo M Pieroni 2006 Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein FASEB J 20 2565 2566
    • (2006) FASEB J , vol.20 , pp. 2565-2566
    • Porto, A.1    Palumbo, R.2    Pieroni, M.3
  • 28
    • 34248342982 scopus 로고    scopus 로고
    • HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques
    • K Inoue K Kawahara KK Biswas 2007 HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques Cardiovasc Pathol 16 136 143
    • (2007) Cardiovasc Pathol , vol.16 , pp. 136-143
    • Inoue, K.1    Kawahara, K.2    Biswas, K.K.3
  • 29
    • 10644254917 scopus 로고    scopus 로고
    • Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: Role of activated macrophages and cytokines
    • N Kalinina A Agrotis Y Antropova 2004 Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines Arterioscler Thromb Vasc Biol 24 2320 2325
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2320-2325
    • Kalinina, N.1    Agrotis, A.2    Antropova, Y.3
  • 30
    • 58149352350 scopus 로고    scopus 로고
    • The HMGB1 receptor RAGE mediates ischemic brain damage
    • S Muhammad W Barakat S Stoyanov 2008 The HMGB1 receptor RAGE mediates ischemic brain damage J Neurosci 28 12023 12031
    • (2008) J Neurosci , vol.28 , pp. 12023-12031
    • Muhammad, S.1    Barakat, W.2    Stoyanov, S.3
  • 31
    • 51649111202 scopus 로고    scopus 로고
    • High mobility group box-1 in ischemia-reperfusion injury of the heart
    • M Andrassy HC Volz JC Igwe 2008 High mobility group box-1 in ischemia-reperfusion injury of the heart Circ 117 3216 32226
    • (2008) Circ , vol.117 , pp. 3216-32226
    • Andrassy, M.1    Volz, H.C.2    Igwe, J.C.3
  • 32
    • 8144223671 scopus 로고    scopus 로고
    • RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
    • O Arancio HP Zhang X Chen 2004 RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice EMBO J 23 4096 4105
    • (2004) EMBO J , vol.23 , pp. 4096-4105
    • Arancio, O.1    Zhang, H.P.2    Chen, X.3
  • 33
    • 0001263746 scopus 로고    scopus 로고
    • Molecular identity and cellular distribution of advanced glycation endproduct receptors: Relationship of p60 to OST-48 and p90 to 80 K-H membrane proteins
    • YM Li T Mitsuhashi D Wojciechowicz 1996 Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80 K-H membrane proteins Proc Natl Acad Sci USA 93 11047 11052
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11047-11052
    • Li, Y.M.1    Mitsuhashi, T.2    Wojciechowicz, D.3
  • 34
    • 0036180791 scopus 로고    scopus 로고
    • CD36 serves a receptor for advanced glycation endproducts (AGEs)
    • N Ohgami R Nagai M Ikemoto 2002 CD36 serves a receptor for advanced glycation endproducts (AGEs) J Diabetes Complicat 16 56 59
    • (2002) J Diabetes Complicat , vol.16 , pp. 56-59
    • Ohgami, N.1    Nagai, R.2    Ikemoto, M.3
  • 35
    • 0346100518 scopus 로고    scopus 로고
    • Scavenging receptors for oxidized and glycated proteins
    • S Horiuchi Y Sakamoto M Sakai 2003 Scavenging receptors for oxidized and glycated proteins Amino Acids 25 283 292
    • (2003) Amino Acids , vol.25 , pp. 283-292
    • Horiuchi, S.1    Sakamoto, Y.2    Sakai, M.3
  • 36
    • 4143087382 scopus 로고    scopus 로고
    • Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells
    • C Lu JC He W Cai 2004 Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells Proc Natl Acad Sci USA 101 11767 11772
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11767-11772
    • Lu, C.1    He, J.C.2    Cai, W.3
  • 37
    • 11144267118 scopus 로고    scopus 로고
    • Characterization of the advanced glycation endproduct receptor complex in the retinal pigment epithelium
    • S McFarlane JV Glenn AM Lichanska 2005 Characterization of the advanced glycation endproduct receptor complex in the retinal pigment epithelium Br J Ophthalmol 89 107 112
    • (2005) Br J Ophthalmol , vol.89 , pp. 107-112
    • McFarlane, S.1    Glenn, J.V.2    Lichanska, A.M.3
  • 38
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • J Tian AM Avalos SY Mao 2007 Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE Nat Immunol 8 487 496
    • (2007) Nat Immunol , vol.8 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.Y.3
  • 39
    • 33746731651 scopus 로고    scopus 로고
    • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
    • M Yu H Wang A Ding 2006 HMGB1 signals through toll-like receptor (TLR) 4 and TLR2 Shock 26 174 179
    • (2006) Shock , vol.26 , pp. 174-179
    • Yu, M.1    Wang, H.2    Ding, A.3
  • 40
    • 0037377697 scopus 로고    scopus 로고
    • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
    • TM Wendt N Tanji J Guo 2003 RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy Am J Pathol 162 1123 1137
    • (2003) Am J Pathol , vol.162 , pp. 1123-1137
    • Wendt, T.M.1    Tanji, N.2    Guo, J.3
  • 41
    • 0029738444 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-β2 microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis
    • T Miyata O Hori J Zhang 1996 The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-β2 microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis J Clin Invest 98 1088 1094
    • (1996) J Clin Invest , vol.98 , pp. 1088-1094
    • Miyata, T.1    Hori, O.2    Zhang, J.3
  • 42
    • 33847296039 scopus 로고    scopus 로고
    • Posttranslationally modified proteins as mediators of sustained intestinal inflammation
    • M Andrassy J Igwe F Autschbach 2006 Posttranslationally modified proteins as mediators of sustained intestinal inflammation Am J Path 169 1223 1237
    • (2006) Am J Path , vol.169 , pp. 1223-1237
    • Andrassy, M.1    Igwe, J.2    Autschbach, F.3
  • 43
    • 34548070752 scopus 로고    scopus 로고
    • Structural and functional insights into RAGE activation by multimeric S100B
    • T Ostendorp E Leclerc A Galichet 2007 Structural and functional insights into RAGE activation by multimeric S100B EMBO J 26 3868 3878
    • (2007) EMBO J , vol.26 , pp. 3868-3878
    • Ostendorp, T.1    Leclerc, E.2    Galichet, A.3
  • 44
    • 33947510205 scopus 로고    scopus 로고
    • Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches
    • J Xie DS Burz W He 2007 Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches J Biol Chem 282 4218 4231
    • (2007) J Biol Chem , vol.282 , pp. 4218-4231
    • Xie, J.1    Burz, D.S.2    He, W.3
  • 45
    • 35748967902 scopus 로고    scopus 로고
    • S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE immunoglobulin domains
    • E Leclerc G Fritz M Weibel 2007 S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE immunoglobulin domains J Biol Chem 282 31317 31331
    • (2007) J Biol Chem , vol.282 , pp. 31317-31331
    • Leclerc, E.1    Fritz, G.2    Weibel, M.3
  • 46
    • 55249118389 scopus 로고    scopus 로고
    • Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE)
    • J Xie S Reverdatto A Frolov 2008 Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE) J Biol Chem 283 27255 27269
    • (2008) J Biol Chem , vol.283 , pp. 27255-27269
    • Xie, J.1    Reverdatto, S.2    Frolov, A.3
  • 47
    • 3042818389 scopus 로고    scopus 로고
    • Morphologic findings of coronary atherosclerotic plaques in diabetics: A postmortem study
    • AP Burke FD Kolodgie A Zieske 2004 Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study Arterioscler Thromb Vasc Biol 24 1266 1271
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1266-1271
    • Burke, A.P.1    Kolodgie, F.D.2    Zieske, A.3
  • 48
    • 0037444761 scopus 로고    scopus 로고
    • Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
    • H Yonekura S Sakurai RG Petrova 2003 Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury Biochem J 370 1097 1109
    • (2003) Biochem J , vol.370 , pp. 1097-1109
    • Yonekura, H.1    Sakurai, S.2    Petrova, R.G.3
  • 49
    • 43249092154 scopus 로고    scopus 로고
    • Identification, classification, and expression of RAGE gene splice variants
    • BI Hudson AM Carter E Harja 2008 Identification, classification, and expression of RAGE gene splice variants FASEB J 22 1572 1580
    • (2008) FASEB J , vol.22 , pp. 1572-1580
    • Hudson, B.I.1    Carter, A.M.2    Harja, E.3
  • 50
    • 54049108485 scopus 로고    scopus 로고
    • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
    • A Raucci S Cugusi A Antonelli 2008 A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10) FASEB J 22 3716 3727
    • (2008) FASEB J , vol.22 , pp. 3716-3727
    • Raucci, A.1    Cugusi, S.2    Antonelli, A.3
  • 51
    • 18244381813 scopus 로고    scopus 로고
    • Plasma levels of soluble receptor for advanced glycation endproducts and coronary artery disease in nondiabetic men
    • C Falcone E Emanuele A D'Angelo 2005 Plasma levels of soluble receptor for advanced glycation endproducts and coronary artery disease in nondiabetic men Arterioscler Thromb Vasc Biol 25 1032 1037
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1032-1037
    • Falcone, C.1    Emanuele, E.2    D'Angelo, A.3
  • 52
    • 33845467745 scopus 로고    scopus 로고
    • Serum endogenous secretory RAGE levels are inversely associated with carotid IMT in type 2 diabetic patients
    • N Katakami M Matsuhisa H Kaneto 2007 Serum endogenous secretory RAGE levels are inversely associated with carotid IMT in type 2 diabetic patients Atherosclerosis 190 22 23
    • (2007) Atherosclerosis , vol.190 , pp. 22-23
    • Katakami, N.1    Matsuhisa, M.2    Kaneto, H.3
  • 53
    • 33847608713 scopus 로고    scopus 로고
    • Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease
    • H Koyama T Shoji S Fukumoto 2007 Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease Arterioscler Thromb Vasc Biol 27 147 153
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 147-153
    • Koyama, H.1    Shoji, T.2    Fukumoto, S.3
  • 54
    • 34250675234 scopus 로고    scopus 로고
    • Serum levels of sRAGE, the soluble form of receptor for advanced glycation endproducts, are associated with inflammatory markers in patients with type 2 diabetes
    • K Nakamura S Yamagishi H Adachi 2007 Serum levels of sRAGE, the soluble form of receptor for advanced glycation endproducts, are associated with inflammatory markers in patients with type 2 diabetes Mol Med 13 185 189
    • (2007) Mol Med , vol.13 , pp. 185-189
    • Nakamura, K.1    Yamagishi, S.2    Adachi, H.3
  • 55
    • 45449083028 scopus 로고    scopus 로고
    • Serum levels of receptor for advanced glycation endproducts (sRAGE) are positively associated with circulating AGEs and soluble form of VCAM-1 in patients with type 2 diabetes
    • K Nakamura S Yamagishi H Adachi 2008 Serum levels of receptor for advanced glycation endproducts (sRAGE) are positively associated with circulating AGEs and soluble form of VCAM-1 in patients with type 2 diabetes Microvasc Res 76 52 56
    • (2008) Microvasc Res , vol.76 , pp. 52-56
    • Nakamura, K.1    Yamagishi, S.2    Adachi, H.3
  • 56
    • 39749117502 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation endproducts is a prognostic factor for heart failure
    • Y Koyama Y Takeishi S Suzuki 2008 Soluble receptor for advanced glycation endproducts is a prognostic factor for heart failure J Card Fail 14 133 139
    • (2008) J Card Fail , vol.14 , pp. 133-139
    • Koyama, Y.1    Takeishi, Y.2    Suzuki, S.3
  • 57
    • 14644408014 scopus 로고    scopus 로고
    • -374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis
    • C Falcone I Campo E Emanuele 2005 -374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis Clin Chim Acta 354 111 116
    • (2005) Clin Chim Acta , vol.354 , pp. 111-116
    • Falcone, C.1    Campo, I.2    Emanuele, E.3
  • 58
    • 39149109304 scopus 로고    scopus 로고
    • The -374T/A RAGE polymorphism protects against future cardiac events in nondiabetic patients with coronary artery disease
    • C Falcone D Geroldi MP Buzzi 2008 The -374T/A RAGE polymorphism protects against future cardiac events in nondiabetic patients with coronary artery disease Arch Med Res 39 320 325
    • (2008) Arch Med Res , vol.39 , pp. 320-325
    • Falcone, C.1    Geroldi, D.2    Buzzi, M.P.3
  • 59
    • 24644515967 scopus 로고    scopus 로고
    • The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study
    • MA Hofmann Q Yang E Harja 2005 The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study Atherosclerosis 182 301 305
    • (2005) Atherosclerosis , vol.182 , pp. 301-305
    • Hofmann, M.A.1    Yang, Q.2    Harja, E.3
  • 60
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • L Park KG Raman KJ Lee 1998 Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts Nat Med 4 1025 1031
    • (1998) Nat Med , vol.4 , pp. 1025-1031
    • Park, L.1    Raman, K.G.2    Lee, K.J.3
  • 61
    • 30944454884 scopus 로고    scopus 로고
    • RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
    • T Wendt E Harja L Bucciarelli 2006 RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes Atherosclerosis 185 70 77
    • (2006) Atherosclerosis , vol.185 , pp. 70-77
    • Wendt, T.1    Harja, E.2    Bucciarelli, L.3
  • 62
    • 24644491335 scopus 로고    scopus 로고
    • Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice
    • RK Vikramadithyan Y Hu HL Noh 2005 Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice J Clin Invest 115 2434 2443
    • (2005) J Clin Invest , vol.115 , pp. 2434-2443
    • Vikramadithyan, R.K.1    Hu, Y.2    Noh, H.L.3
  • 63
    • 0037180531 scopus 로고    scopus 로고
    • RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein e null mice
    • LG Bucciarelli T Wendt W Qu 2002 RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E null mice Circ 106 2827 2835
    • (2002) Circ , vol.106 , pp. 2827-2835
    • Bucciarelli, L.G.1    Wendt, T.2    Qu, W.3
  • 64
    • 52749084063 scopus 로고    scopus 로고
    • RAGE deficiency attenuates the development of atherosclerosis in diabetes
    • A Soro-Paavonen AM Watson J Li 2008 RAGE deficiency attenuates the development of atherosclerosis in diabetes Diabetes 57 2461 2469
    • (2008) Diabetes , vol.57 , pp. 2461-2469
    • Soro-Paavonen, A.1    Watson, A.M.2    Li, J.3
  • 65
    • 14444283590 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products mediates the chemotaxis of rabbit smooth muscle cells
    • T Higashi H Sano T Saishoji 1997 The receptor for advanced glycation end products mediates the chemotaxis of rabbit smooth muscle cells Diabetes 46 463 472
    • (1997) Diabetes , vol.46 , pp. 463-472
    • Higashi, T.1    Sano, H.2    Saishoji, T.3
  • 66
    • 0035650546 scopus 로고    scopus 로고
    • Roles of advanced glycation end products (AGE) and receptor for AGE on vascular smooth muscle cell growth
    • R Wang M Kudo M Yokoyama 2001 Roles of advanced glycation end products (AGE) and receptor for AGE on vascular smooth muscle cell growth J Nippon Med Scho 68 472 481
    • (2001) J Nippon Med Scho , vol.68 , pp. 472-481
    • Wang, R.1    Kudo, M.2    Yokoyama, M.3
  • 67
    • 0030859290 scopus 로고    scopus 로고
    • Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress
    • HM Lander JM Tauras JS Ogiste 1997 Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress J Biol Chem 272 17810 17814
    • (1997) J Biol Chem , vol.272 , pp. 17810-17814
    • Lander, H.M.1    Tauras, J.M.2    Ogiste, J.S.3
  • 68
    • 33744958085 scopus 로고    scopus 로고
    • Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation endproducts in vascular smooth muscle cells
    • MA Reddy SL Li S Sahar 2006 Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation endproducts in vascular smooth muscle cells J Biol Chem 281 13685 13693
    • (2006) J Biol Chem , vol.281 , pp. 13685-13693
    • Reddy, M.A.1    Li, S.L.2    Sahar, S.3
  • 69
    • 0041319299 scopus 로고    scopus 로고
    • S100B-RAGE-mediated augmentation of angiotensin II-induced activation of Jak2 in vascular smooth muscle cells is dependent on PLD2
    • SS Shaw AM Schmidt AK Banes 2003 S100B-RAGE-mediated augmentation of angiotensin II-induced activation of Jak2 in vascular smooth muscle cells is dependent on PLD2 Diabetes 52 2381 2388
    • (2003) Diabetes , vol.52 , pp. 2381-2388
    • Shaw, S.S.1    Schmidt, A.M.2    Banes, A.K.3
  • 70
    • 0037696629 scopus 로고    scopus 로고
    • Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury
    • Z Zhou K Wang MS Penn 2003 Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury Circ 107 2238 2243
    • (2003) Circ , vol.107 , pp. 2238-2243
    • Zhou, Z.1    Wang, K.2    Penn, M.S.3
  • 71
    • 0037380608 scopus 로고    scopus 로고
    • Arterial restenosis: Central role of RAGE-dependent neointimal expansion
    • T Sakaguchi SF Yan SD Yan 2003 Arterial restenosis: central role of RAGE-dependent neointimal expansion J Clin Invest 111 959 972
    • (2003) J Clin Invest , vol.111 , pp. 959-972
    • Sakaguchi, T.1    Yan, S.F.2    Yan, S.D.3
  • 72
    • 33645127464 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma down-regulates receptor for advanced glycation end products and inhibits smooth muscle cell proliferation in a diabetic and nondiabetic rat carotid artery injury model
    • K Wang Z Zhou M Zhang 2006 Peroxisome proliferator-activated receptor gamma down-regulates receptor for advanced glycation end products and inhibits smooth muscle cell proliferation in a diabetic and nondiabetic rat carotid artery injury model J Pharmacol Exp Ther 317 37 43
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 37-43
    • Wang, K.1    Zhou, Z.2    Zhang, M.3
  • 73
    • 33750913676 scopus 로고    scopus 로고
    • Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferators-activated receptor-gamma activation
    • T Yoshida S Yamagishi K Makamura 2006 Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferators-activated receptor-gamma activation Diabetologia 49 3094 3099
    • (2006) Diabetologia , vol.49 , pp. 3094-3099
    • Yoshida, T.1    Yamagishi, S.2    Makamura, K.3
  • 74
    • 42549124546 scopus 로고    scopus 로고
    • Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation endproducts
    • JS Chang T Wendt W Qu 2008 Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation endproducts Circ Res 102 905 913
    • (2008) Circ Res , vol.102 , pp. 905-913
    • Chang, J.S.1    Wendt, T.2    Qu, W.3
  • 75
    • 0033848466 scopus 로고    scopus 로고
    • The expression of advanced glycation endproducts and their cellular receptor RAGE in diabetic nephropathy and non-diabetic renal disease
    • N Tanji GS Markowitz C Fu 2000 The expression of advanced glycation endproducts and their cellular receptor RAGE in diabetic nephropathy and non-diabetic renal disease J Am Soc Nephrol 11 1656 1666
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1656-1666
    • Tanji, N.1    Markowitz, G.S.2    Fu, C.3
  • 76
    • 0029116910 scopus 로고
    • Expression of receptors for advanced glycosylated end products in renal disease
    • M Abel U Ritthaler Y Zhang 1995 Expression of receptors for advanced glycosylated end products in renal disease Nephrol Dial Transplant 19 1662 1667
    • (1995) Nephrol Dial Transplant , vol.19 , pp. 1662-1667
    • Abel, M.1    Ritthaler, U.2    Zhang, Y.3
  • 77
    • 3042668028 scopus 로고    scopus 로고
    • Enhanced expression of receptor for advanced glycation endproducts in chronic kidney disease
    • FF Hou H Ren WF Owen Jr 2004 Enhanced expression of receptor for advanced glycation endproducts in chronic kidney disease J Am Soc Nephrol 15 1889 1896
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1889-1896
    • Hou, F.F.1    Ren, H.2    Owen Jr, W.F.3
  • 78
    • 33646429192 scopus 로고    scopus 로고
    • Relationship between the expression of advanced glycation endproducts (AGE) and the receptor for AGE (RAGE) mRNA in diabetic nephropathy
    • D Suzuki M Toyoda N Yamamoto 2006 Relationship between the expression of advanced glycation endproducts (AGE) and the receptor for AGE (RAGE) mRNA in diabetic nephropathy Intern Med 45 435 441
    • (2006) Intern Med , vol.45 , pp. 435-441
    • Suzuki, D.1    Toyoda, M.2    Yamamoto, N.3
  • 79
    • 32844474342 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation endproducts in patients with decreased renal function
    • M Kalousova M Hodkova M Kazderova 2006 Soluble receptor for advanced glycation endproducts in patients with decreased renal function Am J Kidney Dis 47 406 411
    • (2006) Am J Kidney Dis , vol.47 , pp. 406-411
    • Kalousova, M.1    Hodkova, M.2    Kazderova, M.3
  • 80
    • 34547830269 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts-soluble form and gene polymorphisms in chronic haemodialysis patients
    • M Kalousova M Jachymova O Mestek 2007 Receptor for advanced glycation endproducts-soluble form and gene polymorphisms in chronic haemodialysis patients Nephrol Dial Transplant 22 2020 2026
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 2020-2026
    • Kalousova, M.1    Jachymova, M.2    Mestek, O.3
  • 81
    • 36048944238 scopus 로고    scopus 로고
    • The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients
    • E Lindholm E Bakhtadze M Sjogren 2006 The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients Diabetologia 49 2745 2755
    • (2006) Diabetologia , vol.49 , pp. 2745-2755
    • Lindholm, E.1    Bakhtadze, E.2    Sjogren, M.3
  • 82
    • 14744274872 scopus 로고    scopus 로고
    • Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients
    • G Prevost I Fajardy C Besmond 2005 Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients Diabetes Metabol 31 35 39
    • (2005) Diabetes Metabol , vol.31 , pp. 35-39
    • Prevost, G.1    Fajardy, I.2    Besmond, C.3
  • 83
    • 11144354724 scopus 로고    scopus 로고
    • A 63 bp deletion in the promoter of RAGE correlates with a decreased risk for nephropathy in patients with type 2 diabetes
    • G Rudofsky Jr B Isermann T Schilling 2004 A 63 bp deletion in the promoter of RAGE correlates with a decreased risk for nephropathy in patients with type 2 diabetes Exp Clin Endocrinol Diabetes 112 135 141
    • (2004) Exp Clin Endocrinol Diabetes , vol.112 , pp. 135-141
    • Rudofsky Jr, G.1    Isermann, B.2    Schilling, T.3
  • 84
    • 0842333112 scopus 로고    scopus 로고
    • Relation between development of nephropathy and the p22phox C242T and receptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients
    • S Matsunaga-Irie T Maruyama Y Yamamoto 2004 Relation between development of nephropathy and the p22phox C242T and receptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients Diabetes Care 27 303 307
    • (2004) Diabetes Care , vol.27 , pp. 303-307
    • Matsunaga-Irie, S.1    Maruyama, T.2    Yamamoto, Y.3
  • 85
    • 0037342124 scopus 로고    scopus 로고
    • The functional -374T/A RAGE polymorphism is associated with proteinuria and cardiovascular disease in type 1 diabetic patients
    • K Pettersson-Fernholm C Forsblom BI Hudson 2003 The functional -374T/A RAGE polymorphism is associated with proteinuria and cardiovascular disease in type 1 diabetic patients Diabetes 52 891 894
    • (2003) Diabetes , vol.52 , pp. 891-894
    • Pettersson-Fernholm, K.1    Forsblom, C.2    Hudson, B.I.3
  • 86
    • 0035029634 scopus 로고    scopus 로고
    • Polymorphism screening of four genes encoding advanced glycation endproduct putative receptors. Association study with nephropathy in type 1 diabetic patients
    • O Poirier V Nicaud N Vionnet 2001 Polymorphism screening of four genes encoding advanced glycation endproduct putative receptors. Association study with nephropathy in type 1 diabetic patients Diabetes 50 1214 1218
    • (2001) Diabetes , vol.50 , pp. 1214-1218
    • Poirier, O.1    Nicaud, V.2    Vionnet, N.3
  • 87
    • 20844442808 scopus 로고    scopus 로고
    • Haplotype analysis if the RAGE gene: Identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus
    • K Kankova A Stejskalova M Hertlova 2005 Haplotype analysis if the RAGE gene: identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus Nephrol Dial Transplant 20 1093 1102
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1093-1102
    • Kankova, K.1    Stejskalova, A.2    Hertlova, M.3
  • 88
    • 28444472740 scopus 로고    scopus 로고
    • Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy
    • JM Forbes SR Thorpe V Thallas-Bonke 2005 Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy J Am Soc Nephrol 16 2363 2372
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2363-2372
    • Forbes, J.M.1    Thorpe, S.R.2    Thallas-Bonke, V.3
  • 89
    • 27744574284 scopus 로고    scopus 로고
    • Telmisartan inhibits expression of a receptor for advanced glycation end products (RAGE) in angiotensin II-exposed endothelial cells and decreases serum levels of soluble RAGE in patients with essential hypertension
    • K Nakamura S Yamaghisi Y Nakamura 2005 Telmisartan inhibits expression of a receptor for advanced glycation end products (RAGE) in angiotensin II-exposed endothelial cells and decreases serum levels of soluble RAGE in patients with essential hypertension Microvasc Res 70 137 141
    • (2005) Microvasc Res , vol.70 , pp. 137-141
    • Nakamura, K.1    Yamaghisi, S.2    Nakamura, Y.3
  • 90
    • 33750590947 scopus 로고    scopus 로고
    • RAGE control of diabetic nephropathy in a mouse model: Effects of RAGE gene disruption and administration of low-molecular weight heparin
    • KM Myint Y Yamamoto T Doi 2006 RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin Diabetes 55 2510 2522
    • (2006) Diabetes , vol.55 , pp. 2510-2522
    • Myint, K.M.1    Yamamoto, Y.2    Doi, T.3
  • 91
    • 33645219720 scopus 로고    scopus 로고
    • Renal effects of a neutralizing RAGE antibody in long-term streptozotocin-diabetic mice
    • LJ Jensen L Denner BF Schrijvers 2006 Renal effects of a neutralizing RAGE antibody in long-term streptozotocin-diabetic mice J Endocrinol 188 493 501
    • (2006) J Endocrinol , vol.188 , pp. 493-501
    • Jensen, L.J.1    Denner, L.2    Schrijvers, B.F.3
  • 92
    • 0347360360 scopus 로고    scopus 로고
    • Long-term effects of a neutralizing RAGE antibody in obese type 2 diabetic mice
    • A Flyvbjerg L Denner BF Schrijvers 2004 Long-term effects of a neutralizing RAGE antibody in obese type 2 diabetic mice Diabetes 53 166 172
    • (2004) Diabetes , vol.53 , pp. 166-172
    • Flyvbjerg, A.1    Denner, L.2    Schrijvers, B.F.3
  • 94
    • 44049098885 scopus 로고    scopus 로고
    • RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis
    • J Guo R Ananthakrishnan W Qu 2008 RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis J Am Soc Nephrol 19 961 972
    • (2008) J Am Soc Nephrol , vol.19 , pp. 961-972
    • Guo, J.1    Ananthakrishnan, R.2    Qu, W.3
  • 95
    • 31544463531 scopus 로고    scopus 로고
    • Role of receptor for advanced glycation end-products and signalling events in advanced glycation end-product-induced monocyte chemoattractant protein-1 expression in differentiated mouse podocytes
    • L Gu S Hagiwara Q Fan 2006 Role of receptor for advanced glycation end-products and signalling events in advanced glycation end-product-induced monocyte chemoattractant protein-1 expression in differentiated mouse podocytes Nephrol Dial Transplant 21 299 313
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 299-313
    • Gu, L.1    Hagiwara, S.2    Fan, Q.3
  • 96
    • 0035661067 scopus 로고    scopus 로고
    • Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via RAGE
    • MD Oldfield LA Bach JM Forbes 2001 Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via RAGE J Clin Invest 108 1853 1863
    • (2001) J Clin Invest , vol.108 , pp. 1853-1863
    • Oldfield, M.D.1    Bach, L.A.2    Forbes, J.M.3
  • 97
    • 85047694774 scopus 로고    scopus 로고
    • Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily
    • A Bierhaus KM Haslbeck PM Humpert 2004 Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily J Clin Invest 114 1741 1751
    • (2004) J Clin Invest , vol.114 , pp. 1741-1751
    • Bierhaus, A.1    Haslbeck, K.M.2    Humpert, P.M.3
  • 98
    • 23744467294 scopus 로고    scopus 로고
    • Role of advanced glycation end products and their receptors in development of diabetic neuropathy
    • R Wada S Yagahiashi 2005 Role of advanced glycation end products and their receptors in development of diabetic neuropathy Ann NYAcad Sci 1043 598 604
    • (2005) Ann NYAcad Sci , vol.1043 , pp. 598-604
    • Wada, R.1    Yagahiashi, S.2
  • 99
    • 37149048164 scopus 로고    scopus 로고
    • Evaluation of polyneuropathy markers in type 1 diabetic kidney transplant patients and effects of islet transplantation: Neurophysiological and skin biopsy longitudinal analysis
    • U Del Carro P Fiorina S Amadio 2007 Evaluation of polyneuropathy markers in type 1 diabetic kidney transplant patients and effects of islet transplantation: neurophysiological and skin biopsy longitudinal analysis Diabetes Care 30 3063 3069
    • (2007) Diabetes Care , vol.30 , pp. 3063-3069
    • Del Carro, U.1    Fiorina, P.2    Amadio, S.3
  • 100
    • 38149048613 scopus 로고    scopus 로고
    • SRAGE and esRAGE are not associated with peripheral or autonomic neuropathy in type 2 diabetes
    • PM Humpert G Papadopoulos K Schaefer 2007 sRAGE and esRAGE are not associated with peripheral or autonomic neuropathy in type 2 diabetes Horm Metab Res 39 899 902
    • (2007) Horm Metab Res , vol.39 , pp. 899-902
    • Humpert, P.M.1    Papadopoulos, G.2    Schaefer, K.3
  • 101
    • 42449157139 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts (RAGE) and experimental diabetic neuropathy
    • C Toth LL Rong C Yang 2008 Receptor for advanced glycation endproducts (RAGE) and experimental diabetic neuropathy Diabetes 57 1002 1017
    • (2008) Diabetes , vol.57 , pp. 1002-1017
    • Toth, C.1    Rong, L.L.2    Yang, C.3
  • 102
    • 10044227179 scopus 로고    scopus 로고
    • Antagonism of RAGE suppresses peripheral nerve regeneration
    • LL Rong W Trojaborg W Qu 2004 Antagonism of RAGE suppresses peripheral nerve regeneration FASEB J 18 1812 1817
    • (2004) FASEB J , vol.18 , pp. 1812-1817
    • Rong, L.L.1    Trojaborg, W.2    Qu, W.3
  • 103
    • 10044282944 scopus 로고    scopus 로고
    • RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways
    • LL Rong SF Yan T Wendt 2004 RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways FASEB J 18 1818 1825
    • (2004) FASEB J , vol.18 , pp. 1818-1825
    • Rong, L.L.1    Yan, S.F.2    Wendt, T.3
  • 104
    • 42449159705 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth
    • L Wang S Li FB Jungalwala 2008 Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth J Neurosci Res 86 1254 1266
    • (2008) J Neurosci Res , vol.86 , pp. 1254-1266
    • Wang, L.1    Li, S.2    Jungalwala, F.B.3
  • 105
    • 0036521604 scopus 로고    scopus 로고
    • RAGE-mediated neutrophil dysfunction is evoked by advanced glycation endproducts (AGEs)
    • KS Collison RS Parhar SS Saleh 2002 RAGE-mediated neutrophil dysfunction is evoked by advanced glycation endproducts (AGEs) J Leukoc Biol 71 433 444
    • (2002) J Leukoc Biol , vol.71 , pp. 433-444
    • Collison, K.S.1    Parhar, R.S.2    Saleh, S.S.3
  • 106
    • 0027176945 scopus 로고
    • Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end products
    • AM Schmidt SD Yan J Brett 1993 Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end products J Clin Invest 91 2155 2168
    • (1993) J Clin Invest , vol.91 , pp. 2155-2168
    • Schmidt, A.M.1    Yan, S.D.2    Brett, J.3
  • 107
    • 3142769779 scopus 로고    scopus 로고
    • Blockade of the late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation endproducts
    • Y Chen SS Yan J Colgan 2004 Blockade of the late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation endproducts J Immunol 173 1399 1405
    • (2004) J Immunol , vol.173 , pp. 1399-1405
    • Chen, Y.1    Yan, S.S.2    Colgan, J.3
  • 108
    • 13644264763 scopus 로고    scopus 로고
    • RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB
    • G Cataldegirmen S Zeng N Feirt 2005 RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB J Exp Med 201 473 484
    • (2005) J Exp Med , vol.201 , pp. 473-484
    • Cataldegirmen, G.1    Zeng, S.2    Feirt, N.3
  • 109
    • 2442443134 scopus 로고    scopus 로고
    • Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation
    • D Foell M Frosch C Sorg 2004 Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation Clin Chim Acta 344 37 51
    • (2004) Clin Chim Acta , vol.344 , pp. 37-51
    • Foell, D.1    Frosch, M.2    Sorg, C.3
  • 110
    • 8744311749 scopus 로고    scopus 로고
    • Increased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes
    • A Kosaki T Hasegawa T Kimura 2004 Increased plasma S100A12 (EN-RAGE) levels in patients with type 2 diabetes J Clin Endocrinol Metab 89 5423 5428
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5423-5428
    • Kosaki, A.1    Hasegawa, T.2    Kimura, T.3
  • 111
    • 27844506606 scopus 로고    scopus 로고
    • Plasma concentrations and importance of high mobility group box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation
    • T Hatada H Wada T Nobori 2005 Plasma concentrations and importance of high mobility group box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation Thromb Haemost 94 975 979
    • (2005) Thromb Haemost , vol.94 , pp. 975-979
    • Hatada, T.1    Wada, H.2    Nobori, T.3
  • 112
    • 0036562502 scopus 로고    scopus 로고
    • RAGE and arthritis. the G82S polymorphism amplifies the inflammatory response
    • MA Hofmann S Drury BI Hudson 2002 RAGE and arthritis. The G82S polymorphism amplifies the inflammatory response Genes Immun 3 123 135
    • (2002) Genes Immun , vol.3 , pp. 123-135
    • Hofmann, M.A.1    Drury, S.2    Hudson, B.I.3
  • 113
    • 33846260722 scopus 로고    scopus 로고
    • Blockade of RAGE suppresses alloimmune reactions in vitro and delays allograft rejection in heart transplantation
    • B Moser MJ Szabolcs HJ Ankersmit 2007 Blockade of RAGE suppresses alloimmune reactions in vitro and delays allograft rejection in heart transplantation Am J Transplant 7 293 302
    • (2007) Am J Transplant , vol.7 , pp. 293-302
    • Moser, B.1    Szabolcs, M.J.2    Ankersmit, H.J.3
  • 114
    • 0037351507 scopus 로고    scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
    • SSD Yan ZY Wu HP Zhang 2003 Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system Nat Med 9 287 293
    • (2003) Nat Med , vol.9 , pp. 287-293
    • Yan, S.S.D.1    Wu, Z.Y.2    Zhang, H.P.3
  • 115
    • 56149124859 scopus 로고    scopus 로고
    • RAGE ligation affects T cell activation and controls T cell differentiation
    • Y Chen EM Akirav W Chen 2008 RAGE ligation affects T cell activation and controls T cell differentiation J Immunol 181 4272 4278
    • (2008) J Immunol , vol.181 , pp. 4272-4278
    • Chen, Y.1    Akirav, E.M.2    Chen, W.3
  • 116
    • 40049104961 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo
    • B Moser DD Desai MP Downie 2007 Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo J Immunol 179 8051 8058
    • (2007) J Immunol , vol.179 , pp. 8051-8058
    • Moser, B.1    Desai, D.D.2    Downie, M.P.3
  • 117
    • 34249937629 scopus 로고    scopus 로고
    • Immunohistochemical localization of advanced glycation endproducts (AGEs) and their receptor (RAGE) in polycystic and normal ovaries
    • E Diamanti-Kandarakis C Piperi E Patsouris 2007 Immunohistochemical localization of advanced glycation endproducts (AGEs) and their receptor (RAGE) in polycystic and normal ovaries Histochem Cell Biol 127 581 589
    • (2007) Histochem Cell Biol , vol.127 , pp. 581-589
    • Diamanti-Kandarakis, E.1    Piperi, C.2    Patsouris, E.3
  • 118
    • 51649088386 scopus 로고    scopus 로고
    • Increased serum advanced glycation end products is a distinct finding in lean women with polycystic ovary syndrome (PCOS)
    • E Diamanti-Kandarakis I Katsikis C Piperi 2008 Increased serum advanced glycation end products is a distinct finding in lean women with polycystic ovary syndrome (PCOS) Clin Endocrinol (Oxf) 69 634 641
    • (2008) Clin Endocrinol (Oxf) , vol.69 , pp. 634-641
    • Diamanti-Kandarakis, E.1    Katsikis, I.2    Piperi, C.3
  • 119
    • 2942756123 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
    • B Liliensiek MA Weigand A Bierhaus 2004 Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response J Clin Invest 113 1641 1650
    • (2004) J Clin Invest , vol.113 , pp. 1641-1650
    • Liliensiek, B.1    Weigand, M.A.2    Bierhaus, A.3
  • 120
    • 37749005803 scopus 로고    scopus 로고
    • Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection
    • EC Lutterloh SM Opal DD Pittman 2007 Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection Crit Care 11 R122
    • (2007) Crit Care , vol.11 , pp. 122
    • Lutterloh, E.C.1    Opal, S.M.2    Pittman, D.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.