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Volumn 58, Issue 6, 2011, Pages 641-647

Differential effect of the benzophenanthridine alkaloids sanguinarine and chelerythrine on glycine transporters

Author keywords

Alkaloid; Benzophenanthridine; Chelerythrine; Chelidonium majus; Glycine; GlyT1; GlyT2; Inhibitor; Neurotransmitter; Ouabain; Pain; PKC; Protein kinase C; Sanguinarine; Transporter

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM); BERBERINE; CHELERYTHRINE; GLYCINE; GLYCINE TRANSPORTER; GLYCINE TRANSPORTER 1; GLYCINE TRANSPORTER 2; SANGUINARINE;

EID: 79953687936     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.02.001     Document Type: Article
Times cited : (13)

References (58)
  • 1
    • 77950159448 scopus 로고    scopus 로고
    • Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells
    • N. Aburai, M. Yoshida, M. Ohnishi, and K. Kimura Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells Biosci. Biotechnol. Biochem. 74 2010 548 552
    • (2010) Biosci. Biotechnol. Biochem. , vol.74 , pp. 548-552
    • Aburai, N.1    Yoshida, M.2    Ohnishi, M.3    Kimura, K.4
  • 2
    • 0036139423 scopus 로고    scopus 로고
    • 2 selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons
    • DOI 10.1038/nn778
    • S. Ahmadi, S. Lippross, W.L. Neuhuber, and H.U. Zeilhofer PGE2 selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons Nat. Neurosci. 5 2002 34 40 (Pubitemid 34038780)
    • (2002) Nature Neuroscience , vol.5 , Issue.1 , pp. 34-40
    • Ahmadi, S.1    Lippross, S.2    Neuhuber, W.L.3    Zeilhofer, H.U.4
  • 3
    • 19244375508 scopus 로고    scopus 로고
    • Structure, function and regulation of glycine neurotransporters
    • DOI 10.1016/j.ejphar.2003.08.074
    • C. Aragon, and B. Lopez-Corcuera Structure, function and regulation of glycine neurotransporters Eur. J. Pharmacol. 479 2003 249 262 (Pubitemid 37377893)
    • (2003) European Journal of Pharmacology , vol.479 , Issue.1-3 , pp. 249-262
    • Aragon, C.1    Lopez-Corcuera, B.2
  • 4
    • 77955094281 scopus 로고    scopus 로고
    • Calcium dependent modification of distal C-terminal sequences of glycine transporter GlyT1
    • M. Baliova, and F. Jursky Calcium dependent modification of distal C-terminal sequences of glycine transporter GlyT1 Neurochem. Int. 57 2010 254 261
    • (2010) Neurochem. Int. , vol.57 , pp. 254-261
    • Baliova, M.1    Jursky, F.2
  • 5
    • 0347993813 scopus 로고    scopus 로고
    • Calpain-mediated proteolytic cleavage of the neuronal glycine transporter, GlyT2
    • M. Baliova, H. Betz, and F. Jursky Calpain-mediated proteolytic cleavage of the neuronal glycine transporter, GlyT2 J. Neurochem. 88 2004 227 232 (Pubitemid 38030225)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.1 , pp. 227-232
    • Baliova, M.1    Betz, H.2    Jursky, F.3
  • 6
    • 0027097784 scopus 로고
    • Structure and function of inhibitory glycine receptors
    • H. Betz Structure and function of inhibitory glycine receptors Q. Rev. Biophys. 25 1992 381 394 (Pubitemid 23078701)
    • (1992) Quarterly Reviews of Biophysics , vol.25 , Issue.4 , pp. 381-394
    • Betz, H.1
  • 8
    • 57349094379 scopus 로고    scopus 로고
    • Design of potent GlyT1 inhibitors: In vitro and in vivo profiles
    • T.M. Bridges, R. Williams, and C.W. Lindsley Design of potent GlyT1 inhibitors: in vitro and in vivo profiles Curr. Opin. Mol. Ther. 10 2008 591 601
    • (2008) Curr. Opin. Mol. Ther. , vol.10 , pp. 591-601
    • Bridges, T.M.1    Williams, R.2    Lindsley, C.W.3
  • 10
    • 0042860080 scopus 로고    scopus 로고
    • Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain
    • DOI 10.1038/nature01868
    • J.A. Coull, D. Boudreau, K. Bachand, S.A. Prescott, F. Nault, A. Sik, P. De Koninck, and Y. De Koninck Transsynaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain Nature 424 2003 938 942 (Pubitemid 37051684)
    • (2003) Nature , vol.424 , Issue.6951 , pp. 938-942
    • Coull, J.A.M.1    Boudreau, D.2    Bachand, K.3    Prescott, S.A.4    Nault, F.5    Sik, A.6    De Koninck, P.7    De Koninck, Y.8
  • 11
    • 30744439794 scopus 로고    scopus 로고
    • BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
    • DOI 10.1038/nature04223, PII NATURE04223
    • J.A. Coull, S. Beggs, D. Boudreau, D. Boivin, M. Tsuda, K. Inoue, C. Gravel, M.W. Salter, and Y. De Koninck BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain Nature 438 2005 1017 1021 (Pubitemid 43093974)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 1017-1021
    • Coull, J.A.M.1    Beggs, S.2    Boudreau, D.3    Boivin, D.4    Tsuda, M.5    Inoue, K.6    Gravel, C.7    Salter, M.W.8    De Koninck, Y.9
  • 12
    • 65749112372 scopus 로고    scopus 로고
    • Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain
    • T. Dohi, K. Morita, T. Kitayama, N. Motoyama, and N. Morioka Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain Pharmacol. Ther. 123 2009 54 79
    • (2009) Pharmacol. Ther. , vol.123 , pp. 54-79
    • Dohi, T.1    Morita, K.2    Kitayama, T.3    Motoyama, N.4    Morioka, N.5
  • 13
    • 20444391684 scopus 로고    scopus 로고
    • Glycine transporters: Essential regulators of neurotransmission
    • DOI 10.1016/j.tibs.2005.04.004, PII S0968000405000940, Celebrating 50 Years of the IUBMB
    • V. Eulenburg, W. Armsen, H. Betz, and J. Gomeza Glycine transporters: essential regulators of neurotransmission Trends Biochem. Sci. 30 2005 325 333 (Pubitemid 40799051)
    • (2005) Trends in Biochemical Sciences , vol.30 , Issue.6 , pp. 325-333
    • Eulenburg, V.1    Armsen, W.2    Betz, H.3    Gomeza, J.4
  • 14
    • 33745555489 scopus 로고    scopus 로고
    • Neurotransmitter transporters: Molecular function of important drug targets
    • DOI 10.1016/j.tips.2006.05.003, PII S0165614706001271
    • U. Gether, P.H. Andersen, O.M. Larsson, and A. Schousboe Neurotransmitter transporters: molecular function of important drug targets Trends Pharmacol. Sci. 27 2006 375 383 (Pubitemid 43977787)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.7 , pp. 375-383
    • Gether, U.1    Andersen, P.H.2    Larsson, O.M.3    Schousboe, A.4
  • 17
    • 33646576910 scopus 로고    scopus 로고
    • Dopamine regulation of amiloride-sensitive sodium channels in lung cells
    • M.N. Helms, X.J. Chen, S. Ramosevac, D.C. Eaton, and L. Jain Dopamine regulation of amiloride-sensitive sodium channels in lung cells Am. J. Physiol. 290 2006 L710 L722
    • (2006) Am. J. Physiol. , vol.290
    • Helms, M.N.1    Chen, X.J.2    Ramosevac, S.3    Eaton, D.C.4    Jain, L.5
  • 19
    • 24944439152 scopus 로고    scopus 로고
    • Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
    • K.L. Holton, M.K. Loder, and H.E. Melikian Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization Nat. Neurosci. 8 2005 881 888
    • (2005) Nat. Neurosci. , vol.8 , pp. 881-888
    • Holton, K.L.1    Loder, M.K.2    Melikian, H.E.3
  • 20
    • 67649989298 scopus 로고    scopus 로고
    • Glycine transport inhibitors for the treatment of schizophrenia: Symptom and disease modification
    • D.C Javitt Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modification Curr. Opin. Drug Discov. Devel. 12 2009 468 478
    • (2009) Curr. Opin. Drug Discov. Devel. , vol.12 , pp. 468-478
    • Javitt, D.C.1
  • 21
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • DOI 10.1038/325529a0
    • J.W. Johnson, and P. Ascher Glycine potentiates the NMDA response in cultured mouse brain neurons Nature 325 1987 529 531 (Pubitemid 17056733)
    • (1987) Nature , vol.325 , Issue.6104 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 22
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • N.W. Kleckner, and R. Dingledine Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes Science 241 1988 835 837
    • (1988) Science , vol.241 , pp. 835-837
    • Kleckner, N.W.1    Dingledine, R.2
  • 23
    • 0027438311 scopus 로고
    • Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features
    • Q.R. Liu, B. López-Corcuera, S. Mandiyan, H. Nelson, and N. Nelson Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features J. Biol. Chem. 268 1993 22802 22808 (Pubitemid 23318342)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.30 , pp. 22802-22808
    • Liu, Q.-R.1    Lopez-Corcuera, B.2    Mandiyan, S.3    Nelson, H.4    Nelson, N.5
  • 24
    • 33646241080 scopus 로고    scopus 로고
    • The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding A possible mechanism for its antiproliferative activity
    • M. Lopus, and D. Panda The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding A possible mechanism for its antiproliferative activity FEBS J. 273 2006 2139 2150
    • (2006) FEBS J. , vol.273 , pp. 2139-2150
    • Lopus, M.1    Panda, D.2
  • 25
    • 0034055038 scopus 로고    scopus 로고
    • Effects of persistent nociception on periaqueductal gray glycine release
    • DOI 10.1016/S0306-4522(00)00076-2, PII S0306452200000762
    • S. Maione, I. Marabese, F. Rossi, L. Berrino, E. Palazzo, and L. Trabace Effects of persistent nociception on periaqueductal gray glycine release Neuroscience 97 2000 311 316 (Pubitemid 30224769)
    • (2000) Neuroscience , vol.97 , Issue.2 , pp. 311-316
    • Maione, S.1    Marabese, I.2    Rossi, F.S.3    Berrino, L.4    Palazzo, E.5    Trabace, L.6    Rossi, F.7
  • 26
    • 0019941688 scopus 로고
    • Sanguinarine: A monofunctional intercalation alkaloids
    • M. Maiti, R. Nandi, and K. Chaudhuri Sanguinarine: a monofunctional intercalation alkaloids FEBS Lett. 142 1982 280 284
    • (1982) FEBS Lett. , vol.142 , pp. 280-284
    • Maiti, M.1    Nandi, R.2    Chaudhuri, K.3
  • 27
    • 3042542923 scopus 로고    scopus 로고
    • Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
    • DOI 10.1113/jphysiol.2004.063321
    • M. Martina, Y. Gorfinkel, S. Halman, J.A. Lowe, P. Periyalwar, C.J. Schmidt, and R. Bergeron Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels J. Physiol. 557 2004 489 500 (Pubitemid 38807389)
    • (2004) Journal of Physiology , vol.557 , Issue.2 , pp. 489-500
    • Martina, M.1    Gorfinkel, Y.2    Halman, S.3    Lowe, J.A.4    Periyalwar, P.5    Schmidt, C.J.6    Bergeron, R.7
  • 28
    • 46449103724 scopus 로고    scopus 로고
    • Activation of dorsal periaqueductal gray by glycine produces long lasting hyponociception in rats without overt defensive behaviors
    • M.A. Martins, A.P. Carobrez, and C.R. Tonussi Activation of dorsal periaqueductal gray by glycine produces long lasting hyponociception in rats without overt defensive behaviors Life Sci. 83 2008 118 121
    • (2008) Life Sci. , vol.83 , pp. 118-121
    • Martins, M.A.1    Carobrez, A.P.2    Tonussi, C.R.3
  • 29
    • 0032852641 scopus 로고    scopus 로고
    • Neurotransmitter transporters in the central nervous system
    • J. Masson, C. Sagné, M. Hamon, and S. El Mestikawy Neurotransmitter transporters in the central nervous system Pharmacol. Rev. 51 1999 439 464 (Pubitemid 29420211)
    • (1999) Pharmacological Reviews , vol.51 , Issue.3 , pp. 439-464
    • Masson, J.1    Sagne, C.2    Hamon, M.3    El Mestikawy, S.4
  • 31
    • 56349144133 scopus 로고    scopus 로고
    • The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Ca in C6 glioma cells
    • N. Morioka, J.M. Abdin, K. Morita, T. Kitayama, Y. Nakata, and T. Dohi The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Ca in C6 glioma cells Neurochem. Int. 53 2008 248 254
    • (2008) Neurochem. Int. , vol.53 , pp. 248-254
    • Morioka, N.1    Abdin, J.M.2    Morita, K.3    Kitayama, T.4    Nakata, Y.5    Dohi, T.6
  • 32
    • 47949120019 scopus 로고    scopus 로고
    • Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice
    • K. Morita, N. Motoyama, T. Kitayama, N. Morioka, K. Kifune, and T. Dohi Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice J. Pharmacol. Exp. Ther. 326 2008 633 645
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , pp. 633-645
    • Morita, K.1    Motoyama, N.2    Kitayama, T.3    Morioka, N.4    Kifune, K.5    Dohi, T.6
  • 34
    • 0031753789 scopus 로고    scopus 로고
    • The family of Na+/Cl neurotransmitter transporters
    • N. Nelson The family of Na+/Cl neurotransmitter transporters J. Neurochem. 71 1998 1785 1803
    • (1998) J. Neurochem. , vol.71 , pp. 1785-1803
    • Nelson, N.1
  • 35
    • 0017820504 scopus 로고
    • Effect of sanguinarine, a benzophenanthridine alkaloid, on frog skin potential difference and short circuit current
    • J. Nichols, K.D. Straub, and S. Abernathy Effect of sanguinarine, a benzophenanthridine alkaloid, on frog skin potential difference and short circuit current Biochim. Biophys. Acta 511 1978 251 258 (Pubitemid 8383466)
    • (1978) Biochimica et Biophysica Acta , vol.511 , Issue.2 , pp. 251-258
    • Nichols, J.1    Straub, K.D.2    Abernathy, S.3
  • 37
    • 0019723947 scopus 로고
    • Inhibition of Na K-ATPase activity and ouabain binding by sanguinarine
    • B.J.R. Pitts, and L.R. Meyerson Inhibition of Na K-ATPase activity and ouabain binding by sanguinarine Drug Dev. Res. 1 1981 43 47
    • (1981) Drug Dev. Res. , vol.1 , pp. 43-47
    • Pitts, B.J.R.1    Meyerson, L.R.2
  • 38
    • 33750460927 scopus 로고    scopus 로고
    • Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina i neurons: Towards a biophysical basis for neuropathic pain
    • S.A. Prescott, T.J. Sejnowski, and Y. De Koninck Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain Mol. Pain 2 2006 32
    • (2006) Mol. Pain , vol.2 , pp. 32
    • Prescott, S.A.1    Sejnowski, T.J.2    De Koninck, Y.3
  • 39
    • 0028818536 scopus 로고
    • Modulation of a recombinant glycine transporter (GLYT 1 b) by activation of protein kinase C
    • K. Sato, R. Adams, H. Betz, and P. Schloss Modulation of a recombinant glycine transporter (GLYT 1 b) by activation of protein kinase C J. Neurochem. 65 1995 1967 1973
    • (1995) J. Neurochem. , vol.65 , pp. 1967-1973
    • Sato, K.1    Adams, R.2    Betz, H.3    Schloss, P.4
  • 40
    • 0342871998 scopus 로고    scopus 로고
    • Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores
    • DOI 10.1016/S0031-9422(96)00545-6, PII S0031942296005456
    • T. Schmeller, B. Latz-Bruning, and M. Wink Biochemical activities of berberine, palmitate and sanguinarine mediating chemical defence against microorganism and herbivores Phytochemistry 44 1997 257 266 (Pubitemid 27087925)
    • (1997) Phytochemistry , vol.44 , Issue.2 , pp. 257-266
    • Schmeller, T.1    Latz-Bruning, B.2    Wink, M.3
  • 41
    • 0036163307 scopus 로고    scopus 로고
    • Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV
    • DOI 10.1002/ptr.969
    • A. Sedo, K. Vlasicová, P. Barták, R. Vespalec, J. Vicar, V. Simánek, and J. Ulrichová Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV Phytother. Res. 16 2002 84 87 (Pubitemid 34116704)
    • (2002) Phytotherapy Research , vol.16 , Issue.1 , pp. 84-87
    • Sedo, A.1    Vlasicova, K.2    Bartak, P.3    Vespalec, R.4    Vicar, J.5    Simanek, V.6    Ulrichova, J.7
  • 43
    • 77953289841 scopus 로고    scopus 로고
    • D-Serine and a glycine transporter-1 inhibitor enhance social memory in rats
    • T. Shimazaki, A. Kaku, and S. Chaki d-Serine and a glycine transporter-1 inhibitor enhance social memory in rats Psychopharmacology (Berl.) 209 2010 263 270
    • (2010) Psychopharmacology (Berl.) , vol.209 , pp. 263-270
    • Shimazaki, T.1    Kaku, A.2    Chaki, S.3
  • 44
    • 10744231330 scopus 로고    scopus 로고
    • Modulation of Chelidonii herba on glycine-activated and glutamate-activated ion currents in rat periaqueductal gray neurons
    • DOI 10.1016/j.cccn.2003.07.002
    • M.C. Shin, M.H. Jang, H.K. Chang, S. Lim, S.M. Han, H.J. Park, I. Shim, J.S. Lee, K.A. Kim, and C.J. Kim Modulation of Chelidonii herba on glycine-activated and glutamate-activated ion currents in rat periaqueductal gray neurons Clin. Chim. Acta 337 2003 93 101 (Pubitemid 37329805)
    • (2003) Clinica Chimica Acta , vol.337 , Issue.1-2 , pp. 93-101
    • Shin, M.-C.1    Jang, M.-H.2    Chang, H.-K.3    Lim, S.4    Han, S.-M.5    Park, H.-J.6    Shim, I.7    Lee, J.-S.8    Kim, K.-A.9    Kim, C.-J.10
  • 46
    • 0037102009 scopus 로고    scopus 로고
    • 32P-postlabeling technique
    • DOI 10.1016/S0009-2797(02)00038-8, PII S0009279702000388
    • M. Stiborova, V. Simanek, E. Frei, P. Hobza, and J. Ulrichova DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique Chem. Biol. Interact. 140 2002 231 242 (Pubitemid 35247461)
    • (2002) Chemico-Biological Interactions , vol.140 , Issue.3 , pp. 231-242
    • Stiborova, M.1    Simanek, V.2    Frei, E.3    Hobza, P.4    Ulrichova, J.5
  • 47
    • 34249107728 scopus 로고    scopus 로고
    • Glycine transporter 1 inhibitors and modulation of NMDA receptor-mediated excitatory neurotransmission
    • DOI 10.2174/138945007780618535
    • C. Sur, and G.G. Kinney Glycine transporter 1 inhibitors and modulation of NMDA receptor-mediated excitatory neurotransmission Curr. Drug Targets 8 2007 643 649 (Pubitemid 46785062)
    • (2007) Current Drug Targets , vol.8 , Issue.5 , pp. 643-649
    • Sur, C.1    Kinney, G.G.2
  • 48
    • 42549154180 scopus 로고    scopus 로고
    • Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment
    • DOI 10.1097/ALN.0b013e31816c9044, PII 0000054220080500000022
    • M. Tanabe, K. Takasu, S. Yamaguchi, D. Kodama, and H. Ono Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment Anesthesiology 108 2008 929 937 (Pubitemid 351589490)
    • (2008) Anesthesiology , vol.108 , Issue.5 , pp. 929-937
    • Tanabe, M.1    Takasu, K.2    Yamaguchi, S.3    Kodama, D.4    Ono, H.5
  • 51
    • 0001375676 scopus 로고    scopus 로고
    • Inhibition of eukaryote protein kinases by isoquinoline and oxazine alkaloids
    • DOI 10.1055/s-2006-957749
    • B.H. Wang, Z.X. Lu, and G.M. Polya Inhibition of eukaryote protein kinases by isoquinoline and oxazine alkaloids Planta Med. 63 1997 494 498 (Pubitemid 28035441)
    • (1997) Planta Medica , vol.63 , Issue.6 , pp. 494-498
    • Wang, B.H.1    Lu, Z.X.2    Polya, G.M.3
  • 52
    • 2942644495 scopus 로고    scopus 로고
    • Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo
    • DOI 10.1016/j.neuroscience.2004.04.006, PII S0306452204002702
    • K.J. Whitehead, S.M. Pearce, G. Walker, H. Sundaram, D. Hill, and N.G. Bowery Positive N-methyl-d-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo Neuroscience 126 2004 381 390 (Pubitemid 38780814)
    • (2004) Neuroscience , vol.126 , Issue.2 , pp. 381-390
    • Whitehead, K.J.1    Pearce, S.M.2    Walker, G.3    Sundaram, H.4    Hill, D.5    Bowery, N.G.6
  • 53
    • 0031788303 scopus 로고    scopus 로고
    • Modes of action of allelochemical alkaloids: Interaction with neuroreceptors, DNA, and other molecular targets
    • M. Wink, T. Schmeller, and B. Latz-Brüning Modes of action of allelochemical alkaloids: interaction with neuroreceptors, DNA, and other molecular targets J. Chem. Ecol. 24 1998 1881 1937 (Pubitemid 28546056)
    • (1998) Journal of Chemical Ecology , vol.24 , Issue.11 , pp. 1881-1937
    • Wink, M.1    Schmeller, T.2    Latz-Bruning, B.3
  • 54
    • 0027742463 scopus 로고
    • Antimicrotubule properties of benzophenanthridine alkaloids
    • DOI 10.1021/bi00211a047
    • J. Wolff, and L. Knipling Antimicrotubule properties of benzophenanthridine alkaloids Biochemistry 32 1993 13334 13339 (Pubitemid 24005944)
    • (1993) Biochemistry , vol.32 , Issue.48 , pp. 13334-13339
    • Wolff, J.1    Knipling, L.2
  • 55
    • 38449086833 scopus 로고    scopus 로고
    • NMDA receptor regulation by D-serine: New findings and perspectives
    • DOI 10.1007/s12035-007-0038-6
    • H Wolosker NMDA receptor regulation by d-serine: new findings and perspectives Mol. Neurobiol. 36 2007 152 164 (Pubitemid 351360344)
    • (2007) Molecular Neurobiology , vol.36 , Issue.2 , pp. 152-164
    • Wolosker, H.1
  • 57
    • 43049176638 scopus 로고    scopus 로고
    • Spinal dis-inhibition in inflammatory pain
    • H.U. Zeilhofer, and U.B. Zeilhofer Spinal dis-inhibition in inflammatory pain Neurosci. Lett. 437 2008 170 174
    • (2008) Neurosci. Lett. , vol.437 , pp. 170-174
    • Zeilhofer, H.U.1    Zeilhofer, U.B.2


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