메뉴 건너뛰기




Volumn 53, Issue 6-8, 2008, Pages 248-254

The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Cα in C6 glioma cells

Author keywords

C6 glioma cells; Glycine transporter; Protein kinase C; RNA interference; Uptake

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; GLYCINE TRANSPORTER 1; INGENOL; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; ROTTLERIN;

EID: 56349144133     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.08.002     Document Type: Article
Times cited : (16)

References (44)
  • 1
    • 0028932701 scopus 로고
    • Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents
    • Adams R.H., Sato K., Shimada S., Tohyama M., Puschel A.W., and Betz H. Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents. J. Neurosci. 15 (1995) 2524-2532
    • (1995) J. Neurosci. , vol.15 , pp. 2524-2532
    • Adams, R.H.1    Sato, K.2    Shimada, S.3    Tohyama, M.4    Puschel, A.W.5    Betz, H.6
  • 2
    • 16244392441 scopus 로고    scopus 로고
    • Role of protein kinase Cβ in phorbol ester-induced c-fos gene expression in neurons of normotensive and spontaneously hypertensive rat brains
    • Amemiya T., Kambe T., Fukumori R., and Kubo T. Role of protein kinase Cβ in phorbol ester-induced c-fos gene expression in neurons of normotensive and spontaneously hypertensive rat brains. Brain Res. 1040 (2005) 129-136
    • (2005) Brain Res. , vol.1040 , pp. 129-136
    • Amemiya, T.1    Kambe, T.2    Fukumori, R.3    Kubo, T.4
  • 3
    • 0035051189 scopus 로고    scopus 로고
    • The role of protein kinase C in the regulation of serotonin-2A receptor expression
    • Anji A., Hanley N.R.S., Kumari M., and Hensler J.G. The role of protein kinase C in the regulation of serotonin-2A receptor expression. J. Neurochem. 77 (2001) 589-597
    • (2001) J. Neurochem. , vol.77 , pp. 589-597
    • Anji, A.1    Hanley, N.R.S.2    Kumari, M.3    Hensler, J.G.4
  • 4
    • 19244375508 scopus 로고    scopus 로고
    • Structure, function and regulation of glycine neurotransporters
    • Aragón C., and López-Corcuera B. Structure, function and regulation of glycine neurotransporters. Eur. J. Pharmacol. 479 (2003) 249-262
    • (2003) Eur. J. Pharmacol. , vol.479 , pp. 249-262
    • Aragón, C.1    López-Corcuera, B.2
  • 5
    • 0032588967 scopus 로고    scopus 로고
    • Gö6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase
    • Behrens M.M., Strasser U., and Choi D.W. Gö6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. J. Neurochem. 72 (1999) 919-924
    • (1999) J. Neurochem. , vol.72 , pp. 919-924
    • Behrens, M.M.1    Strasser, U.2    Choi, D.W.3
  • 6
    • 0028868306 scopus 로고
    • Differential correlation between translocation and down-regulation of conventional and new protein kinase C isozymes in C6 glioma cells
    • Chen C.-C., Cheng C.-S., Chang J., and Huang H.-C. Differential correlation between translocation and down-regulation of conventional and new protein kinase C isozymes in C6 glioma cells. J. Neurochem. 64 (1995) 818-824
    • (1995) J. Neurochem. , vol.64 , pp. 818-824
    • Chen, C.-C.1    Cheng, C.-S.2    Chang, J.3    Huang, H.-C.4
  • 7
    • 0036135861 scopus 로고    scopus 로고
    • Protein kinase C ε mediates the induction of P-glycoprotein in LNCaP prostate carcinoma cells
    • Flescher E., and Rotem R. Protein kinase C ε mediates the induction of P-glycoprotein in LNCaP prostate carcinoma cells. Cell Signal. 14 (2002) 37-43
    • (2002) Cell Signal. , vol.14 , pp. 37-43
    • Flescher, E.1    Rotem, R.2
  • 9
    • 0343340425 scopus 로고    scopus 로고
    • Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A
    • Geerlings A., López-Corcuera B., and Aragón C. Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A. FEBS Lett. 470 (2000) 51-54
    • (2000) FEBS Lett. , vol.470 , pp. 51-54
    • Geerlings, A.1    López-Corcuera, B.2    Aragón, C.3
  • 10
    • 0028917854 scopus 로고
    • Regulation by phorbol ester of the glycine transporter (GLYT1) in glioblastoma cells
    • Gomeza J., Zafra F., Olivares L., Giménez C., and Aragón C. Regulation by phorbol ester of the glycine transporter (GLYT1) in glioblastoma cells. Biochim. Biophys. Acta 1233 (1995) 41-46
    • (1995) Biochim. Biophys. Acta , vol.1233 , pp. 41-46
    • Gomeza, J.1    Zafra, F.2    Olivares, L.3    Giménez, C.4    Aragón, C.5
  • 11
    • 10744221393 scopus 로고    scopus 로고
    • Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition
    • Gomeza J., Hülsmann S., Ohno K., Eulenburg V., Szöke K., Richter D., and Betz H. Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition. Neuron. 40 (2003) 785-796
    • (2003) Neuron. , vol.40 , pp. 785-796
    • Gomeza, J.1    Hülsmann, S.2    Ohno, K.3    Eulenburg, V.4    Szöke, K.5    Richter, D.6    Betz, H.7
  • 12
    • 0036784075 scopus 로고    scopus 로고
    • Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes
    • González M.I., Kazanietz M.G., and Robinson M.B. Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol. Pharmacol. 62 (2002) 901-910
    • (2002) Mol. Pharmacol. , vol.62 , pp. 901-910
    • González, M.I.1    Kazanietz, M.G.2    Robinson, M.B.3
  • 13
    • 24144479448 scopus 로고    scopus 로고
    • Evidence that protein kinase Cα interacts with and regulates the glial glutamate transporter GLT-1
    • González M.I., Susarla B.T.S., and Robinson M.B. Evidence that protein kinase Cα interacts with and regulates the glial glutamate transporter GLT-1. J. Neurochem. 94 (2005) 1180-1188
    • (2005) J. Neurochem. , vol.94 , pp. 1180-1188
    • González, M.I.1    Susarla, B.T.S.2    Robinson, M.B.3
  • 17
    • 33947432427 scopus 로고    scopus 로고
    • High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study
    • Henjum S., and Hassel B. High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study. Neurochem. Int. 50 (2007) 696-702
    • (2007) Neurochem. Int. , vol.50 , pp. 696-702
    • Henjum, S.1    Hassel, B.2
  • 18
    • 0027322679 scopus 로고
    • Protein kinase C isoenzymes: divergence in signal transduction
    • Hug H., and Sarre T.F. Protein kinase C isoenzymes: divergence in signal transduction. Biochem. J. 291 (1993) 329-343
    • (1993) Biochem. J. , vol.291 , pp. 329-343
    • Hug, H.1    Sarre, T.F.2
  • 19
    • 0037063691 scopus 로고    scopus 로고
    • Gö6976 inhibits LPS-induced microglial TNFα release by suppressing p38 MAP kinase activation
    • Jeohn G.H., Cooper C.L., Jang K.J., Liu B., Lee D.S., Kim H.C., and Hong J.S. Gö6976 inhibits LPS-induced microglial TNFα release by suppressing p38 MAP kinase activation. Neuroscience 114 (2002) 689-697
    • (2002) Neuroscience , vol.114 , pp. 689-697
    • Jeohn, G.H.1    Cooper, C.L.2    Jang, K.J.3    Liu, B.4    Lee, D.S.5    Kim, H.C.6    Hong, J.S.7
  • 20
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson J.W., and Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325 (1987) 529-531
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 21
    • 0037195777 scopus 로고    scopus 로고
    • Protein kinase C activation decreases cell surface expression of the GLT-1 subtypes of glutamate transporter
    • Kalandadze A., Wu Y., and Robinson M.B. Protein kinase C activation decreases cell surface expression of the GLT-1 subtypes of glutamate transporter. J. Biol. Chem. 277 (2002) 45741-45750
    • (2002) J. Biol. Chem. , vol.277 , pp. 45741-45750
    • Kalandadze, A.1    Wu, Y.2    Robinson, M.B.3
  • 22
    • 0020356002 scopus 로고
    • Decrease in cytosolic calcium/phospholipids-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells
    • Kraft A.S., Anderson W.B., Cooper H.L., and Sando J.J. Decrease in cytosolic calcium/phospholipids-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells. J. Biol. Chem. 257 (1982) 13193-13196
    • (1982) J. Biol. Chem. , vol.257 , pp. 13193-13196
    • Kraft, A.S.1    Anderson, W.B.2    Cooper, H.L.3    Sando, J.J.4
  • 23
    • 0034973097 scopus 로고    scopus 로고
    • The glycinergic inhibitory synapse
    • Legendre P. The glycinergic inhibitory synapse. Cell. Mol. Life Sci. 58 (2001) 760-793
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 760-793
    • Legendre, P.1
  • 24
    • 4644370994 scopus 로고    scopus 로고
    • Blockade of glycine transporter-1 (GLYT1) potentiates NMDA receptor-mediated synaptic transmission in hypoglossal motorneurons
    • Lim R., Hoang P., and Berger A.J. Blockade of glycine transporter-1 (GLYT1) potentiates NMDA receptor-mediated synaptic transmission in hypoglossal motorneurons. J. Neurophysiol. 92 (2004) 2530-2537
    • (2004) J. Neurophysiol. , vol.92 , pp. 2530-2537
    • Lim, R.1    Hoang, P.2    Berger, A.J.3
  • 25
    • 0027438311 scopus 로고
    • Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features
    • Liu Q.R., Lopez-Corcuera B., Mandiyan S., Nelson H., and Nelson N. Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features. J. Biol. Chem. 268 (1993) 22802-22808
    • (1993) J. Biol. Chem. , vol.268 , pp. 22802-22808
    • Liu, Q.R.1    Lopez-Corcuera, B.2    Mandiyan, S.3    Nelson, H.4    Nelson, N.5
  • 26
    • 3042542923 scopus 로고    scopus 로고
    • Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
    • Martina M., Gorfinkel Y., Halman S., Lowe J.A., Periyalwar P., Schmidt C.J., and Bergeron R. Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels. J. Physiol. 557 (2004) 489-500
    • (2004) J. Physiol. , vol.557 , pp. 489-500
    • Martina, M.1    Gorfinkel, Y.2    Halman, S.3    Lowe, J.A.4    Periyalwar, P.5    Schmidt, C.J.6    Bergeron, R.7
  • 28
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor H., and Parker P.J. The extended protein kinase C superfamily. Biochem. J. 332 (1998) 281-292
    • (1998) Biochem. J. , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 29
    • 47949120019 scopus 로고    scopus 로고
    • Spinal anti-allodynia action of glycine transporter inhibitors in neuropathic pain models in mice
    • Morita K., Motoyama N., Kitayama T., Morioka N., Kifune K., and Dohi T. Spinal anti-allodynia action of glycine transporter inhibitors in neuropathic pain models in mice. J. Pharmacol. Exp. Ther. 326 (2008) 633-645
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , pp. 633-645
    • Morita, K.1    Motoyama, N.2    Kitayama, T.3    Morioka, N.4    Kifune, K.5    Dohi, T.6
  • 30
    • 0035413601 scopus 로고    scopus 로고
    • Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
    • Newton A.C. Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem. Rev. 101 (2001) 2353-2364
    • (2001) Chem. Rev. , vol.101 , pp. 2353-2364
    • Newton, A.C.1
  • 31
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334 (1988) 661-665
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 33
    • 37049030023 scopus 로고    scopus 로고
    • The synaptic and nonsynaptic glycine transporter type-1 inhibitors Org-24461 and NFPS alter single neuron firing rate in the rat dorsal raphe nucleus. Further evidence for a glutamatergic-serotonergic interaction and its role in antipsychotic action
    • Papp A., Juranyi Z., Nagymajtenyi L., Matyus P., and Harsing Jr. L.G. The synaptic and nonsynaptic glycine transporter type-1 inhibitors Org-24461 and NFPS alter single neuron firing rate in the rat dorsal raphe nucleus. Further evidence for a glutamatergic-serotonergic interaction and its role in antipsychotic action. Neurochem. Int. 52 (2008) 130-134
    • (2008) Neurochem. Int. , vol.52 , pp. 130-134
    • Papp, A.1    Juranyi, Z.2    Nagymajtenyi, L.3    Matyus, P.4    Harsing Jr., L.G.5
  • 34
    • 0037312280 scopus 로고    scopus 로고
    • Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a
    • Pearlman R.J., Aubrey K.R., and Vandenberg R.J. Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a. J. Neurochem. 84 (2003) 592-601
    • (2003) J. Neurochem. , vol.84 , pp. 592-601
    • Pearlman, R.J.1    Aubrey, K.R.2    Vandenberg, R.J.3
  • 35
    • 36849002929 scopus 로고    scopus 로고
    • Functional expression of release-regulating glycine transporters GLYT1 on GABAergic neurons and GLYT2 on astrocytes in mouse spinal cord
    • Raiteri L., Stigliani S., Usai C., Diaspro A., Paluzzi S., Milanese M., Raiteri M., and Bonanno G. Functional expression of release-regulating glycine transporters GLYT1 on GABAergic neurons and GLYT2 on astrocytes in mouse spinal cord. Neurochem. Int. 52 (2008) 103-112
    • (2008) Neurochem. Int. , vol.52 , pp. 103-112
    • Raiteri, L.1    Stigliani, S.2    Usai, C.3    Diaspro, A.4    Paluzzi, S.5    Milanese, M.6    Raiteri, M.7    Bonanno, G.8
  • 36
    • 0033516666 scopus 로고    scopus 로고
    • Protein kinase C δ is essential for etoposide-induced apoptosis in salivary gland acinar cells
    • Reyland M.E., Anderson S.M., Matassa A.A., Barzen K.A., and Quissell D.O. Protein kinase C δ is essential for etoposide-induced apoptosis in salivary gland acinar cells. J. Biol. Chem. 274 (1999) 19115-19123
    • (1999) J. Biol. Chem. , vol.274 , pp. 19115-19123
    • Reyland, M.E.1    Anderson, S.M.2    Matassa, A.A.3    Barzen, K.A.4    Quissell, D.O.5
  • 37
    • 0034213119 scopus 로고    scopus 로고
    • Involvement of the actin cytoskeleton in the regulation of serotonin transporter (SET) activity: possible mechanism underlying SET regulation by protein kinase C
    • Sakai N., Kodama N., Ohmori S., Sasaki K., and Saito N. Involvement of the actin cytoskeleton in the regulation of serotonin transporter (SET) activity: possible mechanism underlying SET regulation by protein kinase C. Neurochem. Int. 36 (2000) 567-579
    • (2000) Neurochem. Int. , vol.36 , pp. 567-579
    • Sakai, N.1    Kodama, N.2    Ohmori, S.3    Sasaki, K.4    Saito, N.5
  • 38
    • 0028818536 scopus 로고
    • Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C
    • Sato K., Adams R., Betz H., and Schloss P. Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C. J. Neurochem. 65 (1995) 1967-1973
    • (1995) J. Neurochem. , vol.65 , pp. 1967-1973
    • Sato, K.1    Adams, R.2    Betz, H.3    Schloss, P.4
  • 39
    • 36849089633 scopus 로고    scopus 로고
    • Characterization of interactions between phencyclidine and amphetamine in rodent prefrontal cortex and striatum: implications in NMDA/glycine-site-mediated dopaminergic dysregulation and dopamine transporter function
    • Sershen H., Balla A., Aspromonte J.M., Xie S., Cooper T.B., and Javitt D.C. Characterization of interactions between phencyclidine and amphetamine in rodent prefrontal cortex and striatum: implications in NMDA/glycine-site-mediated dopaminergic dysregulation and dopamine transporter function. Neurochem. Int. 52 (2008) 119-129
    • (2008) Neurochem. Int. , vol.52 , pp. 119-129
    • Sershen, H.1    Balla, A.2    Aspromonte, J.M.3    Xie, S.4    Cooper, T.B.5    Javitt, D.C.6
  • 40
    • 11244253958 scopus 로고    scopus 로고
    • The protein kinase C inhibitor Gö6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor
    • Shah B.H., Olivares-Reyes J.A., and Catt K.J. The protein kinase C inhibitor Gö6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] potentiates agonist-induced mitogen-activated protein kinase activation through tyrosine phosphorylation of the epidermal growth factor receptor. Mol. Pharmacol. 67 (2005) 184-194
    • (2005) Mol. Pharmacol. , vol.67 , pp. 184-194
    • Shah, B.H.1    Olivares-Reyes, J.A.2    Catt, K.J.3
  • 41
    • 0036310523 scopus 로고    scopus 로고
    • Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1
    • Sugiura T., Tominaga M., Katsuya H., and Mizumura K. Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J. Neurophysiol. 88 (2002) 544-548
    • (2002) J. Neurophysiol. , vol.88 , pp. 544-548
    • Sugiura, T.1    Tominaga, M.2    Katsuya, H.3    Mizumura, K.4
  • 42
    • 0041802953 scopus 로고    scopus 로고
    • Rottlerin, an inhibitor of protein kinase Cδ (PKCδ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCδ-independent
    • Susarla B.T., and Robinson M.B. Rottlerin, an inhibitor of protein kinase Cδ (PKCδ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCδ-independent. J. Neurochem. 86 (2003) 635-645
    • (2003) J. Neurochem. , vol.86 , pp. 635-645
    • Susarla, B.T.1    Robinson, M.B.2
  • 43
    • 0034194092 scopus 로고    scopus 로고
    • Identification of PKC-isoform-specific biological actions using pharmacological approaches
    • Way K.J., Chou E., and King G.L. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol. Sci. 21 (2000) 181-187
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 181-187
    • Way, K.J.1    Chou, E.2    King, G.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.